DSM - CLE

$163 Find Cheap Flights from Des Moines to Cleveland - Compare and Save

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Everything you should know

Cheapest round-trip
$298
Typical prices: $320-$466
Delta
Fri 11/23Fri 12/21
DSM - CLE • 1 stop
Cheapest one-way
$163
Typical prices: $148-$288
Delta
Mon 2/5
DSM - CLE • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Cleveland. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
November
Cheapest • 22% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Atlanta Hartsfield-Jackson (ATL)
Cheapest • Avg $308 (round-trip)
Chicago Midway (MDW)
Shortest trip • 3h 50m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Cleveland (DSM-CLE)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Cleveland

Mon, Nov 23 - Mon, Dec 21
Delta Logo
5:30 am - 12:02 pmDSM  Des Moines-CLE Cleveland Hopkins Intl
5h 32m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:55 am - 11:56 amCLE  Cleveland Hopkins Intl-DSM Des Moines
6h 01m1 stop Minneapolis St Paul
$298Delta
Fri, Nov 27 - Fri, Dec 4
American Airlines Logo
1:58 pm - 9:54 pmDSM  Des Moines-CLE Cleveland Hopkins Intl
6h 56m1 stop Chicago O'Hare Intl
American Airlines Logo
9:04 pm - 8:52 amCLE  Cleveland Hopkins Intl-DSM Des Moines
12h 48m1 stop Chicago O'Hare Intl
$306American Airlines
Fri, Nov 27 - Fri, Dec 4
Southwest Logo
5:25 am - 10:10 amDSM  Des Moines-CLE Cleveland Hopkins Intl
3h 45m1 stop Chicago Midway
Southwest Logo
3:50 pm - 10:05 pmCLE  Cleveland Hopkins Intl-DSM Des Moines
7h 15m2 stops Baltimore/Washington Chicago Midway
$316Southwest
Fri, Dec 11 - Fri, Dec 18
Delta Logo
5:29 pm - 11:59 pmDSM  Des Moines-CLE Cleveland Hopkins Intl
5h 30m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:10 am - 9:50 amCLE  Cleveland Hopkins Intl-DSM Des Moines
4h 40m1 stop Detroit Metropolitan Wayne County
$318Delta
Fri, Dec 11 - Fri, Dec 18
Southwest Logo
4:25 pm - 11:15 pmDSM  Des Moines-CLE Cleveland Hopkins Intl
5h 50m2 stops Chicago Midway Lambert-St Louis
Southwest Logo
8:05 pm - 11:35 pmCLE  Cleveland Hopkins Intl-DSM Des Moines
4h 30m1 stop Chicago Midway
$323Southwest
Tue, Jan 19 - Sat, Jan 23
United Airlines Logo
4:46 pm - 10:28 pmDSM  Des Moines-CLE Cleveland Hopkins Intl
4h 42m1 stop Chicago O'Hare Intl
United Airlines Logo
8:31 am - 12:17 pmCLE  Cleveland Hopkins Intl-DSM Des Moines
4h 46m1 stop Chicago O'Hare Intl
$325United Airlines
Fri, Feb 5 - Mon, Feb 8
American Airlines Logo
2:39 pm - 10:34 pmDSM  Des Moines-CLE Cleveland Hopkins Intl
6h 55m1 stop Chicago O'Hare Intl
American Airlines Logo
5:06 am - 9:56 amCLE  Cleveland Hopkins Intl-DSM Des Moines
5h 50m1 stop Chicago O'Hare Intl
$325American Airlines
Wed, Nov 25 - Tue, Dec 1
Delta Logo
6:52 pm - 12:57 amDSM  Des Moines-CLE Cleveland Hopkins Intl
5h 05m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:10 am - 9:50 amCLE  Cleveland Hopkins Intl-DSM Des Moines
4h 40m1 stop Detroit Metropolitan Wayne County
$325Delta
Sat, Nov 28 - Sat, Dec 5
United Airlines Logo
8:00 am - 1:08 pmDSM  Des Moines-CLE Cleveland Hopkins Intl
4h 08m1 stop Chicago O'Hare Intl
United Airlines Logo
4:02 pm - 7:19 pmCLE  Cleveland Hopkins Intl-DSM Des Moines
4h 17m1 stop Chicago O'Hare Intl
$327United Airlines
Mon, Nov 9 - Thu, Nov 12
Multiple Airlines Logo
8:04 pm - 3:40 pmDSM  Des Moines-CLE Cleveland Hopkins Intl
18h 36m2 stops Las Vegas Harry Reid Intl Denver Intl
Multiple Airlines Logo
7:18 am - 3:25 pmCLE  Cleveland Hopkins Intl-DSM Des Moines
9h 07m1 stop Fort Lauderdale
$380Multiple Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Cleveland flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to Cleveland?

Round-trip flights from Des Moines to Cleveland typically range from $320 to $466. The lowest price found in the past 5 days was $298, on Delta.

What's the cheapest day of the week to fly from Des Moines to Cleveland?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Des Moines to Cleveland. It’s 19% cheaper than the average day, while Thursday is the most expensive, with prices 23% higher.

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Key details for Des Moines to Cleveland flights

Low season

February

Cheapest flight

$163
Beat the crowds with an average 64% drop in travelers.
The most popular month to fly with an average 51% increase in travelers.
One-way flight from Des Moines to Cleveland

When to book flights from Des Moines to Cleveland

Are your dates flexible? Find out the best times to travel from Des Moines to Cleveland based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Cleveland flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Cleveland?

    Two cabin classes are available on flights from Des Moines to Cleveland:

    • Economy Class
    • First Class

  • How long is a flight from Des Moines to Cleveland?

    A nonstop flight from Des Moines to Cleveland takes 00m, covering 610 miles.

  • Do I need a passport to fly from Des Moines to Cleveland?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Des Moines to Cleveland flight?

    Round-trip flights from Des Moines to Cleveland range from $320 to $466, with an average of $378 over the past 12 months. Anything below $320 counts as a good deal.

  • Have flight prices from Des Moines to Cleveland changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $298 to $2,773. That means the highest observed fare was about 9x higher than the lowest one.

  • How are flight prices from Des Moines to Cleveland looking right now?

    One-way fares from Des Moines to Cleveland are currently in line with typical prices for this route. Average one-way fares are about $195.

  • What car rental options are available at Cleveland Hopkins Intl Airport (CLE)?

    Cleveland Hopkins Intl Airport (CLE) hosts 5 major car rental companies, with daily rates averaging $71 for economy cars. Top options include:

    • Hertz
    • Budget
    • Alamo
    • Dollar
    • Thrifty

  • Which airports can I use when flying from Des Moines to Cleveland?

    Flights from Des Moines to Cleveland usually depart from Des Moines (DSM) and arrive at Cleveland Hopkins Intl (CLE).

  • Which airports do connecting flights from Des Moines to Cleveland pass through?

    One-stop flights from Des Moines to Cleveland most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 60% of one-stop connections
    • Chicago Midway (MDW) - 21% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 10% of one-stop connections
    • Minneapolis St Paul (MSP) - 6% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to Cleveland?

    Yes. Flexible dates can save you up to 34% on flights from Des Moines to Cleveland. Tuesday is the cheapest departure day at $308 round-trip on average, while Thursday is the most expensive at $466, a difference of $158.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Des Moines to Cleveland?

    Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 3h 50m, compared with 4h 26m via Minneapolis St Paul (MSP) and 4h 30m via Detroit Metropolitan Wayne County (DTW).

  • What is the time difference between Des Moines and Cleveland?

    Cleveland is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Cleveland?

    Some of the most popular sights in Cleveland are Progressive Field, Huntington Bank Field and Rock and Roll Hall of Fame. These are among the most viewed places in Cleveland on KAYAK.

Your guide to booking Des Moines to Cleveland flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Thursday. On this route, Tuesday flights average $308, about $158 less than Thursday fares (34% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Cleveland trip for November. Fares historically average $296 round-trip in that month - typically $640 less than the most expensive month, which is April (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Cleveland Hopkins Intl Airport.

    • Hilton Garden Inn Cleveland Airport
    • Extended Stay America Select Suites - Cleveland - Airport

More options for your flight from Des Moines to Cleveland

Complete your trip to Cleveland with a hotel stay or car rental

Car rentals in Cleveland
Hotels in Cleveland
Vacations in Cleveland