DSM - ECP

$170 Find Cheap Flights from Des Moines to Panama City - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$339
Typical prices: $358-$515
United Airlines
Sun 1/7Thu 1/11
DSM - ECP • 1 stop
Cheapest one-way
$170
Typical prices: $203-$383
Delta
Mon 2/26
DSM - ECP • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Panama City. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
September
Cheapest • 24% price drop
April
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Washington, D.C. Reagan-National (DCA)
Cheapest • Avg $304 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 4h 47m (one-way)
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Insights
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Flight Deals

Cheap Flights from Des Moines to Panama City (DSM-ECP)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Panama City

Tue, Dec 1 - Fri, Dec 4
American Airlines Logo
3:25 pm - 8:39 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
5h 14m1 stop Dallas/Fort Worth
American Airlines Logo
3:56 pm - 11:05 pmECP  Panama City NW Florida Beaches-DSM Des Moines
7h 09m1 stop Dallas/Fort Worth
$339American Airlines
Thu, Jan 7 - Mon, Jan 11
United Airlines Logo
8:00 am - 2:21 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
6h 21m1 stop Houston George Bush Intcntl
United Airlines Logo
2:56 pm - 10:30 pmECP  Panama City NW Florida Beaches-DSM Des Moines
7h 34m1 stop Houston George Bush Intcntl
$339United Airlines
Tue, Jan 5 - Tue, Jan 12
United Airlines Logo
8:00 am - 1:27 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
5h 27m1 stop Chicago O'Hare Intl
United Airlines Logo
4:40 pm - 10:30 pmECP  Panama City NW Florida Beaches-DSM Des Moines
5h 50m1 stop Houston George Bush Intcntl
$339United Airlines
Tue, Dec 1 - Fri, Dec 4
United Airlines Logo
8:00 am - 1:17 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
5h 17m1 stop Chicago O'Hare Intl
United Airlines Logo
1:30 pm - 11:15 pmECP  Panama City NW Florida Beaches-DSM Des Moines
9h 45m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$344United Airlines
Tue, Jan 5 - Tue, Jan 12
Southwest Logo
6:00 am - 6:15 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
12h 15m2 stops Chicago Midway Nashville Intl
Southwest Logo
7:50 am - 9:30 pmECP  Panama City NW Florida Beaches-DSM Des Moines
13h 40m2 stops Nashville Intl Chicago Midway
$371Southwest
Wed, Feb 3 - Sun, Feb 7
American Airlines Logo
10:57 am - 5:26 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
6h 29m1 stop Charlotte Douglas
American Airlines Logo
5:59 pm - 11:03 pmECP  Panama City NW Florida Beaches-DSM Des Moines
5h 04m1 stop Charlotte Douglas
$371American Airlines
Wed, Feb 3 - Sun, Feb 7
Southwest Logo
6:55 am - 3:15 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
8h 20m2 stops Denver Intl Dallas Love Field
Southwest Logo
1:05 pm - 11:05 pmECP  Panama City NW Florida Beaches-DSM Des Moines
10h 00m2 stops Nashville Intl Chicago Midway
$397Southwest
Fri, Jan 1 - Tue, Mar 23
Delta Logo
4:00 pm - 9:32 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
5h 32m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 10:18 amECP  Panama City NW Florida Beaches-DSM Des Moines
4h 18m1 stop Atlanta Hartsfield-Jackson
$418Delta
Fri, Jan 1 - Wed, Mar 24
Delta Logo
4:00 pm - 9:32 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
5h 32m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 10:18 amECP  Panama City NW Florida Beaches-DSM Des Moines
4h 18m1 stop Atlanta Hartsfield-Jackson
$418Delta
Sat, Feb 27 - Sat, Mar 6
American Airlines Logo
7:18 am - 2:03 pmDSM  Des Moines-ECP Panama City NW Florida Beaches
6h 45m1 stop Chicago O'Hare Intl
American Airlines Logo
3:48 pm - 9:53 pmECP  Panama City NW Florida Beaches-DSM Des Moines
6h 05m1 stop Washington, D.C. Reagan-National
$438American Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Panama City flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to Panama City?

Round-trip flights from Des Moines to Panama City typically range from $358 to $515. The lowest price found in the past 5 days was $339, on United Airlines.

What's the cheapest day of the week to fly from Des Moines to Panama City?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Des Moines to Panama City. It’s 16% cheaper than the average day, while Tuesday is the most expensive, with prices 116% higher.

Find deals

Key details for Des Moines to Panama City flights

Low season

November

Cheapest flight

$170
Beat the crowds with an average 77% drop in travelers.
The most popular month to fly with an average 90% increase in travelers.
One-way flight from Des Moines to Panama City

When to book flights from Des Moines to Panama City

Are your dates flexible? Find out the best times to travel from Des Moines to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Panama City flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Panama City?

    Only Economy Class is available on flights from Des Moines to Panama City.

  • How long is a flight from Des Moines to Panama City?

    A nonstop flight from Des Moines to Panama City takes 00m, covering 887 miles.

  • Do I need a passport to fly from Des Moines to Panama City?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Des Moines to Panama City flight?

    Round-trip flights from Des Moines to Panama City range from $358 to $515, with an average of $426 over the past 12 months. Anything below $358 counts as a good deal.

  • Have flight prices from Des Moines to Panama City changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $339 to $1,174. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Des Moines to Panama City looking right now?

    One-way fares from Des Moines to Panama City are currently higher than usual. Average one-way flight prices are about $272, which is 7% above the typical average for this route.

  • What car rental options are available at Panama City NW Florida Beaches Airport (ECP)?

    Panama City NW Florida Beaches Airport (ECP) hosts 5 major car rental companies, with daily rates averaging $67 for economy cars. Top options include:

    • Dollar
    • Hertz
    • Budget
    • Alamo
    • Avis

  • Which airports can I use when flying from Des Moines to Panama City?

    Flights from Des Moines to Panama City usually depart from Des Moines (DSM) and arrive at Panama City NW Florida Beaches (ECP).

  • Which airports do connecting flights from Des Moines to Panama City pass through?

    One-stop flights from Des Moines to Panama City most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 49% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 26% of one-stop connections
    • Chicago Midway (MDW) - 8% of one-stop connections
    • Dallas/Fort Worth (DFW) - 5% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to Panama City?

    Yes. Flexible dates can save you up to 62% on flights from Des Moines to Panama City. Saturday is the cheapest departure day at $358 round-trip on average, while Tuesday is the most expensive at $922, a difference of $564.

    Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How much time can I save by choosing a different layover airport from Des Moines to Panama City?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 4h 47m, compared with 6h 02m via Dallas/Fort Worth (DFW) and 6h 05m via Chicago Midway (MDW).

Your guide to booking Des Moines to Panama City flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Saturday departure and avoid flying on Tuesday. On this route, Saturday flights average $358, about $564 less than Tuesday fares (61% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Panama City trip for September. Fares historically average $324 round-trip in that month - typically $234 less than the most expensive month, which is July (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Panama City NW Florida Beaches Airport.

    • Hilton Garden Inn Panama City Airport

More options for your flight from Des Moines to Panama City

Complete your trip to Panama City with a hotel stay or car rental

Car rentals in Panama City
Hotels in Panama City