Find Deals on Flights from Des Moines to San Antonio (DSM - SAT)

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to San Antonio

(Round-trip)
Depart: Wed Mar 22 2017 Return: Tue Mar 28 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
9:37a
SAT
1:32p
3h 55m
1 stop
SAT
2:30a
DSM
8:57a
6h 27m
1 stop
Depart: Tue Mar 28 2017 Return: Wed Mar 29 2017 Trip spans 2 days
United
United
DSM
1:55p
SAT
6:45p
4h 50m
1 stop
SAT
3:39p
DSM
7:59p
4h 20m
1 stop
Depart: Wed Mar 29 2017 Return: Tue Apr 4 2017 Trip spans 7 days
Delta
Delta
DSM
1:09p
SAT
7:23p
6h 14m
1 stop
SAT
4:00a
DSM
12:30p
8h 30m
1 stop
Depart: Fri May 12 2017 Return: Sun May 14 2017 Trip spans 3 days
Major Airline
Major Airline
DSM
1:00a
SAT
2:44a
1h 44m
nonstop
SAT
1:00a
DSM
2:44a
1h 44m
nonstop
Depart: Tue May 9 2017 Return: Wed May 17 2017 Trip spans 9 days
American Airlines
American Airlines
DSM
9:37a
SAT
3:09p
5h 32m
1 stop
SAT
2:35p
DSM
6:21p
3h 46m
1 stop
Depart: Thu Mar 30 2017 Return: Tue Apr 4 2017 Trip spans 6 days
United
United
DSM
1:30a
SAT
9:04a
7h 34m
1 stop
SAT
8:39a
DSM
1:25p
4h 46m
1 stop
Depart: Sat May 13 2017 Return: Sat May 20 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
9:37a
SAT
1:33p
3h 56m
1 stop
SAT
3:45a
DSM
8:57a
5h 12m
1 stop
Depart: Wed May 10 2017 Return: Mon May 15 2017 Trip spans 6 days
United
United
DSM
1:40p
SAT
7:59p
6h 19m
1 stop
SAT
3:32p
DSM
7:39p
4h 07m
1 stop
Depart: Sat Apr 22 2017 Return: Sat Apr 29 2017 Trip spans 8 days
Major Airline
Major Airline
DSM
2:00a
SAT
3:44a
1h 44m
nonstop
SAT
2:00a
DSM
3:44a
1h 44m
nonstop
Depart: Mon Mar 20 2017 Return: Wed Mar 22 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
9:37a
SAT
2:53p
5h 16m
1 stop
SAT
4:05a
DSM
8:57a
4h 52m
1 stop
Depart: Thu Apr 27 2017 Return: Mon May 1 2017 Trip spans 5 days
United
United
DSM
1:55p
SAT
7:55p
6h 00m
1 stop
SAT
3:38p
DSM
7:44p
4h 06m
1 stop
Depart: Mon Mar 27 2017 Return: Wed Mar 29 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
9:37a
SAT
2:14p
4h 37m
1 stop
SAT
2:30a
DSM
8:57a
6h 27m
1 stop
Depart: Mon Apr 10 2017 Return: Tue Apr 11 2017 Trip spans 2 days
American Airlines
American Airlines
DSM
3:13p
SAT
7:31p
4h 18m
1 stop
SAT
4:10a
DSM
9:37a
5h 27m
1 stop
Depart: Thu Mar 23 2017 Return: Tue Mar 28 2017 Trip spans 6 days
United
United
DSM
1:30a
SAT
9:04a
7h 34m
1 stop
SAT
9:55a
DSM
2:55p
5h 00m
1 stop
Depart: Tue Apr 18 2017 Return: Mon Apr 24 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
3:13p
SAT
7:31p
4h 18m
1 stop
SAT
2:35p
DSM
6:37p
4h 02m
1 stop
Depart: Wed Apr 19 2017 Return: Mon Apr 24 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
9:37a
SAT
3:09p
5h 32m
1 stop
SAT
2:35p
DSM
6:37p
4h 02m
1 stop
Depart: Wed Jun 7 2017 Return: Tue Jun 13 2017 Trip spans 7 days
United
United
DSM
1:40p
SAT
7:59p
6h 19m
1 stop
SAT
3:35p
DSM
7:40p
4h 05m
1 stop
Depart: Mon Mar 6 2017 Return: Mon Mar 13 2017 Trip spans 7 days
Major Airline
Major Airline
DSM
12:00a
SAT
1:44a
1h 44m
nonstop
SAT
9:00a
DSM
10:44a
1h 44m
nonstop
Depart: Thu Apr 20 2017 Return: Tue Apr 25 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
3:13p
SAT
7:31p
4h 18m
1 stop
SAT
12:30p
DSM
6:37p
6h 07m
1 stop
Depart: Sun May 14 2017 Return: Mon May 15 2017 Trip spans 2 days
United
United
DSM
1:40p
SAT
6:44p
5h 04m
1 stop
SAT
3:32p
DSM
7:39p
4h 07m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Des Moines
$216
Destination

San Antonio
$216