DSM - SAT

$124 Find Cheap Flights from Des Moines to San Antonio

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to San Antonio departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Antonio

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Antonio, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Antonio, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Des Moines to San Antonio (DSM-SAT)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to San Antonio that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to San Antonio

Wed, Oct 15 - Tue, Oct 21
Delta Logo
6:39 pm - 12:20 amDSM-SAT
5h 41m1 stop
Delta Logo
6:25 am - 1:59 pmSAT-DSM
7h 34m1 stop
$255Delta
Find Deal
Thu, Oct 30 - Tue, Nov 4
Delta Logo
10:00 am - 3:56 pmDSM-SAT
5h 56m1 stop
Delta Logo
5:14 am - 1:28 pmSAT-DSM
8h 14m1 stop
$263Delta
Find Deal
Thu, Oct 23 - Tue, Oct 28
Southwest Logo
4:35 pm - 11:40 pmDSM-SAT
7h 05m1 stop
Southwest Logo
11:55 am - 8:55 pmSAT-DSM
9h 00m2 stops
$268Southwest
Find Deal
Thu, Oct 23 - Mon, Oct 27
Southwest Logo
4:35 pm - 11:40 pmDSM-SAT
7h 05m1 stop
Southwest Logo
5:05 pm - 11:30 pmSAT-DSM
6h 25m1 stop
$271Southwest
Find Deal
Thu, Oct 16 - Tue, Oct 21
Frontier Logo
2:37 pm - 7:41 pmDSM-SAT
5h 04m1 stop
Frontier Logo
3:59 pm - 1:52 pmSAT-DSM
21h 53m1 stop
$292Frontier
Find Deal
Thu, Dec 25 - Tue, Dec 30
American Airlines Logo
8:45 am - 5:26 pmDSM-SAT
8h 41m1 stop
American Airlines Logo
6:41 am - 1:21 pmSAT-DSM
6h 40m1 stop
$298American Airlines
Find Deal
Fri, Sep 19 - Sun, Sep 21
Frontier Logo
2:25 pm - 2:27 pmDSM-SAT
24h 02m1 stop
Frontier Logo
8:20 pm - 1:40 pmSAT-DSM
17h 20m1 stop
$309Frontier
Find Deal
Fri, Oct 3 - Fri, Oct 17
American Airlines Logo
7:08 am - 12:14 pmDSM-SAT
5h 06m1 stop
American Airlines Logo
6:24 pm - 11:23 pmSAT-DSM
4h 59m1 stop
$335American Airlines
Find Deal
Thu, Oct 30 - Tue, Nov 4
United Airlines Logo
9:01 am - 4:58 pmDSM-SAT
7h 57m1 stop
United Airlines Logo
5:30 am - 4:07 pmSAT-DSM
10h 37m2 stops
$338United Airlines
Find Deal
Wed, Oct 15 - Mon, Oct 20
United Airlines Logo
3:05 pm - 9:29 pmDSM-SAT
6h 24m1 stop
United Airlines Logo
5:56 pm - 10:28 pmSAT-DSM
4h 32m1 stop
$411United Airlines
Find Deal

Everything you should know

Top airlines
Delta
Cheapest • from $255 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 38% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
August
Cheapest • 16% price drop
March
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$255
Overall average: $372
Delta
Wed 10/15Tue 10/21
DSM - SAT • 1 stop
Cheapest one-way
$124
Typical prices: $283-426
Frontier
Thu 10/2
DSM - SAT • 1 stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Antonio!
Booking Insights

KAYAK's insights & trends for Des Moines to San Antonio flights

Get data-powered insights and trends into flights from Des Moines to San Antonio to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to San Antonio?

The average price of all round-trip flights from Des Moines to San Antonio clicked on KAYAK for each day over the last 12 months.

For Des Moines to San Antonio, Wednesday is the cheapest day to fly on average and Monday is the most expensive. Flying from San Antonio back to Des Moines, the best deals are generally found on Tuesday, with Sunday being the most expensive.

What is the cheapest month to fly from Des Moines to San Antonio?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to San Antonio, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to San Antonio is August, where tickets cost $326 (return) on average. On the other hand, the most expensive months are June and March, where the average cost of round-trip tickets is $479 and $476 respectively.

How far in advance should I book a flight from Des Moines to San Antonio?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to San Antonio, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to San Antonio, you should book around 3 weeks before departure, which saves you about 38% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$124
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 22% increase in price.
Flight from Des Moines to San Antonio

When to book flights from Des Moines to San Antonio

Are your dates flexible? Find out the best times to travel from Des Moines to San Antonio based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to San Antonio

  • What is the cheapest flight from Des Moines to San Antonio?

    In the last 3 days, the lowest price for a flight from Des Moines to San Antonio was $124 for a one-way ticket and $255 for a round-trip.

  • Do I need a passport to fly between Des Moines and San Antonio?

    A passport is not required to fly from Des Moines to San Antonio.

  • Which airports will I be using when flying from Des Moines to San Antonio?

    When flying out of Des Moines you will be using Des Moines. You will be landing at San Antonio, also known as San Antonio.

  • Which aircraft models fly most regularly from Des Moines to San Antonio?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to San Antonio?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and San Antonio, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to San Antonio, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Des Moines to San Antonio are Southwest and Delta. With an average price for the route of $386 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $361 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Des Moines to San Antonio?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to San Antonio.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to San Antonio?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Antonio from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to San Antonio?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Antonio with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SAT can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to San Antonio?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Antonio from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Des Moines to San Antonio

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to San Antonio. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to San Antonio? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4242 reviews
8.0Comfort
7.0Food
8.1Boarding
7.5Entertainment
8.6Crew
Airline reviews

As always, the entire Southwest experience was wonderful, from online booking to flight to baggage retrieval. Very grateful.

10.0 ExcellentRobert, Sep 2025SFO - LAS
Read more Southwest reviews

As always, the entire Southwest experience was wonderful, from online booking to flight to baggage retrieval. Very grateful.

The weather could have been better. There was a 40 minute ATC delay in SFO because of marine fog and a micro cell storm delayed landing and take-off at Nashville. The gate was changed 5 minutes from boarding from gate B3 to gate C23 at Nashville airport.

Was good. I miss the free 2 checked bags. That was part of what made Southwest special

After being assaulted by a flight attendant I was then brushed off as oh well because he long braids didn’t mean to whip me in the eye. I have filed complaints and will see. But like any other issue I’ve had with kayak involved it’s been trash. Last time I’ll be using your app

AC sub par. WiFi not working correctly. Ac sucked. Seats very narrow.

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

Southwest's seats are the least comfortable I have ever sat in.

The cabin was quiet for the redeye flight. The area was clean. The staff was great. The 787 Max was in good condition. Drawbacks were that the seat widths were tight for some passengers. The seat padding was at best average and for a long flight uncomfortable.

Multiple delays and gate changes. Arrived at final destination 6 hours late. All rental cars had been taken.

The movies using Southwest WiFi kept pausing and I had to restart multiple times.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

The flight attendants in SLC were rude. I arrived 40 minutes early to gate. Ticket said I needed check in for seat assignments and tried check in and attendants said they weren’t doing it. And proceeded to never call me to give me a ticket so when time to board I received the very last seat. Please relay to employees to do their job better..,

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

The seats got pretty uncomfortable pretty fast. The armrests are bigger than on other planes, so I had less room in the actual seat. My butt hurt by the end of the flight. :/ comfort was the primary issue. The crew were fantastic!

Armrest controller on my seat 35D and nextbooennseat 35E did not work right. Hard to press buttons to recognize and 35D had constantnpressure either upmost down somit was nearly impossible to make selections. .

I flew with my dog and had already purchased my dog’s ticket. Even that morning I had called costumer service to insure that my husband and I had seats together since the website was giving me an error when choosing our seats and the representative mentioned our dog. I showed up early to the airport and when I got to the gate and we started boarding I was help back and told that I was supposed to have a yellow tag and that I should have checked in at the counter for them to give me that tag. I was not aware of this, the representative on the phone did not say anything. Nor did I see it anywhere in the checking process online, so if you travel with a pet and are not checking in luggage, just know that you still have to go to the check in counter when arriving at the airport unless you want to be the last one to board and not have room for your carry on in the overhead bins. Other than that, I had a great experience.

This flight was perfect. No complaints and only the highest regard for the crew and ground staff and how they executed perfectly. I fly a lot with United and would request predictability and transparency in their operations instead of last minute changes.

This is for UA2274 from Houston to Sacramento. The flight was delayed arriving due to mechanical issues so we left about 3 hours later than scheduled. When boarding the plane the temperature inside was excessive - likely close to 100. Pilot apologized and said it was going to improve at altitude, which it did. But before that I honestly thought there might have been more delays removing passengers made ill from the heat. We were delayed leaving due to another mechanical issue. There was not water on the plane due to a panel that was not secured. They did that quickly, but the combination of mechanical issues was rather disturbing and did not reflect well on United.

United sent me a mileage plus number last year but that number is invalid so I can’t use it to check into flights or collect mileage. There is human to speak about the problem, only computers who keep asking me if I am using the correct email. It’s so frustrating and I cannot resolve it.

The woman gate agent in Phoenix was none too sympathetic about my check-in process as I am relatively new with using apps. I almost did not get on because she said I did not check-in. I thought I had via Kayak where I purchased a very expensive ticket. Lesson learned but to be told I may not get on as a matter of factly was difficult to hear.

Very rough getting into denver. my kid threw up it was so rough.

Gate agent did not hold flight for connection, provided no assistance to get new flight

The plane pushed back from the gate on time. However, it stopped on the ramp, and we waited for over 20 minutes before the aircraft pulled back to the gate. Apparently, something of importance had to be removed from the aircraft by the gate agent. I found this to be odd. The delay was not significant, but I felt that whatever was on the aircraft that had to be taken off, should’ve been done before we pushed back from the gate.

Smooth boarding process. Early departure, smooth flight, early arrival. The entertainment package has very good recent movie options. The flight crew were friendly and professional.

Having to reschedule flights a day later, they loaded by luggage on the wrong plane from Little rock now I have to HOPE they deliver it to where im staying like they said would. International flight crew was very disgruntled and not very friendly.

The entertainment package was vast and the selections were very current. Keep updating it was great.

Great flight. No issues at all. I still think boarding could be more efficient but otherwise, a good experience.

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

Delayed flight, so I switched fights to SFO to Phoenix , Phoenix to DSM. Excellent service through American Airlines

The AA app really sucks ... Every flight & connecting flights were delayed over 30 mins. One connecting flight on American Eagle said it was delayed in its arrival ... when it was actually parked across from the gate for over 1 hr before they pulled it to the gate. Seats in the economy/ main cabin are packed together like sardines ... no leg room.

The flight delay in Dallas created a domino effect that impacted all connecting flights, leading to an increase in the number of connections. As a result, I missed my flight from Casablanca to Marrakech due to the tight turnaround when landing in Casablanca. CMN Airport was understaffed; only one employee was available to assist passengers while others just stood by and watched. It was an extremely frustrating situation. Many passengers were crying and banging their hands on the counter while talking to customer service representative Allabough. Unfortunately, Allabough couldn’t change my flight in the system. At the same time, I was on the phone with an American Airlines customer service representative named Solomon, who said he couldn’t make the change either. So, I decided to take an ONYA Voyages train from Casablanca to Marrakech to reach my destination on Friday, June 26. It turned out to be an unpredictable trip.

Pretty bad gate mgmt upon arrival. No open gates and we had to wait at midnight. Shouldn’t be a surprise that an aircraft is coming in.

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