DSM - SAT

$163 Find Cheap Flights from Des Moines to San Antonio

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to San Antonio departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Antonio

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Antonio, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Antonio, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$181
Overall average: $442
American Airlines
Wed 1/7Wed 1/14
DSM - SAT • 1 stop
Cheapest one-way
$163
Typical prices: $180-$223
Multiple Airlines
Wed 12/17
DSM - SAT • 1 stop
Top airlines
American Airlines
Cheapest • from $207 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 49% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
August
Cheapest • 20% price drop
March
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Antonio!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to San Antonio (DSM-SAT)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to San Antonio that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to San Antonio

Wed, Jan 7 - Wed, Jan 14
American Airlines Logo
4:00 pm - 10:58 pm
DSM
-
SAT
6h 58m1 stop
American Airlines Logo
1:08 pm - 5:06 pm
SAT
-
DSM
3h 58m1 stop
$181American Airlines
Mon, Feb 2 - Wed, Feb 11
American Airlines Logo
4:25 pm - 11:58 pm
DSM
-
SAT
7h 33m1 stop
American Airlines Logo
8:16 am - 3:15 pm
SAT
-
DSM
6h 59m1 stop
$207American Airlines
Wed, Jan 7 - Wed, Jan 14
Southwest Logo
6:10 am - 12:50 pm
DSM
-
SAT
6h 40m1 stop
Southwest Logo
12:25 pm - 9:10 pm
SAT
-
DSM
8h 45m2 stops
$224Southwest
Wed, Jan 7 - Wed, Jan 14
Southwest Logo
3:20 pm - 11:05 pm
DSM
-
SAT
7h 45m2 stops
Southwest Logo
12:25 pm - 9:10 pm
SAT
-
DSM
8h 45m2 stops
$229Southwest
Sat, Jan 17 - Sat, Jan 24
Delta Logo
1:03 pm - 8:43 pm
DSM
-
SAT
7h 40m1 stop
Delta Logo
5:20 am - 12:15 pm
SAT
-
DSM
6h 55m1 stop
$233Delta
Fri, Jan 9 - Sun, Jan 11
Multiple Airlines Logo
8:17 pm - 3:00 pm
DSM
-
SAT
18h 43m1 stop
Multiple Airlines Logo
6:30 am - 10:09 pm
SAT
-
DSM
15h 39m2 stops
$235Multiple Airlines
Sat, Feb 21 - Tue, Feb 24
American Airlines Logo
10:09 am - 6:01 pm
DSM
-
SAT
7h 52m2 stops
American Airlines Logo
6:00 am - 10:47 am
SAT
-
DSM
4h 47m1 stop
$236American Airlines
Sat, Jan 17 - Sat, Jan 24
United Airlines Logo
3:04 pm - 7:41 pm
DSM
-
SAT
4h 37m1 stop
United Airlines Logo
5:25 am - 2:33 pm
SAT
-
DSM
9h 08m2 stops
$238United Airlines
Tue, Feb 3 - Mon, Feb 9
Southwest Logo
6:10 am - 12:50 pm
DSM
-
SAT
6h 40m1 stop
Southwest Logo
2:45 pm - 10:15 pm
SAT
-
DSM
7h 30m2 stops
$239Southwest
Tue, Feb 3 - Mon, Feb 9
Southwest Logo
8:35 am - 4:05 pm
DSM
-
SAT
7h 30m2 stops
Southwest Logo
3:55 pm - 10:15 pm
SAT
-
DSM
6h 20m2 stops
$244Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to San Antonio flights

Get data-powered insights and trends into flights from Des Moines to San Antonio to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to San Antonio?

The average price of all round-trip flights from Des Moines to San Antonio clicked on KAYAK for each day over the last 12 months.

For Des Moines to San Antonio, Wednesday is the cheapest day to fly on average and Monday is the most expensive. Flying from San Antonio back to Des Moines, the best deals are generally found on Tuesday, with Sunday being the most expensive.

What is the cheapest month to fly from Des Moines to San Antonio?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to San Antonio, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to San Antonio is August, where tickets cost $324 (return) on average. On the other hand, the most expensive months are March and June, where the average cost of round-trip tickets is $496 and $479 respectively.

How far in advance should I book a flight from Des Moines to San Antonio?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to San Antonio, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to San Antonio, you should book around 3 weeks before departure, which saves you about 49% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$163
Best time to beat the crowds but there is an average 15% increase in price.
Most popular time to fly with an average 22% increase in price.
Flight from Des Moines to San Antonio

When to book flights from Des Moines to San Antonio

Are your dates flexible? Find out the best times to travel from Des Moines to San Antonio based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to San Antonio

  • What is the cheapest flight from Des Moines to San Antonio?

    In the last 3 days, the lowest price for a flight from Des Moines to San Antonio was $163 for a one-way ticket and $181 for a round-trip.

  • Do I need a passport to fly between Des Moines and San Antonio?

    A passport is not required to fly from Des Moines to San Antonio.

  • Which airports will I be using when flying from Des Moines to San Antonio?

    When flying out of Des Moines you will be using Des Moines. You will be landing at San Antonio, also known as San Antonio.

  • Which aircraft models fly most regularly from Des Moines to San Antonio?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to San Antonio?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Des Moines and San Antonio, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to San Antonio, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Des Moines to San Antonio are Southwest and Delta. With an average price for the route of $421 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $365 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Des Moines to San Antonio?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to San Antonio.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to San Antonio?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Antonio from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to San Antonio?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Antonio with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SAT can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to San Antonio?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Antonio from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Des Moines to San Antonio

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to San Antonio. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to San Antonio? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4251 reviews
8.6Crew
8.0Comfort
7.5Entertainment
7.0Food
8.1Boarding
Airline reviews

Airline travel is always too cramped to really be pleasant, but the cabin crew on this flight did a pretty good job of making up for it by putting on some music during boarding and sprinkling a few funny remarks into the safety briefing and announcements, and just generally being friendly and helpful. It definitely reminded me of why I prefer the in-flight experience on Southwest!

10.0 ExcellentDavid, Nov 2025
BUF - PHX
Read more Southwest reviews

Airline travel is always too cramped to really be pleasant, but the cabin crew on this flight did a pretty good job of making up for it by putting on some music during boarding and sprinkling a few funny remarks into the safety briefing and announcements, and just generally being friendly and helpful. It definitely reminded me of why I prefer the in-flight experience on Southwest!

No delays and arrived to destination 30 min early. Staff was super friendly.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

It was rough. The staff was unprofessional, the choice of on board drinks terrible, it was cramped in space at every airport, they always ran out of overhead bin space so they pressured people to check bags for free or we couldn’t leave on the plane— so I did check my bag to help, and they nearly lost my bag. My bag did not arrive on the luggage belt, another man on my flight and I had to waste our time going to the baggage office to search for our bags. I would only fly southwest again if it was my last choice. Also, my flights were consistently delayed over and over again— at one point they straight up told us we were waiting for the pilot to arrive.

Crew could have been friendlier, maybe I'm spoiled by SW crews. In flight wifi was good. Would be nice to have more food offerings on a 4 plus hour flight

Everything a cheap airline should be at normal airline rates.

Full cans of soda would be nice. A choice between two snacks would be appreciated.

Tried watching free movie and it kept freezing so I couldn’t finish.

I was re-booked onto another flight because my original flight was delayed and I would have missed my connector. I ended up in the “C” group after paying extra to be in the “A “ group on the original flight. At least if you’re going to re-book people, re-book them into the same group.

Was good. I miss the free 2 checked bags. That was part of what made Southwest special

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

Ot was overall fine. Left on time and had basic snacks. Weather was finicky but that’s not the airlines fault.

Even though we were delayed, we were able to make our connection

Crew and customer service were excellent. This flight also had plenty of leg room and seat mounted screens for entertainment. A very pleasant flight all around!

I was in first class. The outlets at my seat did not work. The plane was shabby and run down. I had prepurchsed a day subscription for internet that was not redeemable. I had to repurchase the internet for my flight and then it didn’t work anyway. Quite disappointed in what was supposed to be the launch of a great vacation.

Flight was good and crew was super polite. However, there were around 5 kids screaming the WHOLE 2 hours. I understand kids have to come but parents need to do something to control their children. They make the experience terrible, especially after finishing 16 hour shifts at the hospital I needed some sleep, which I did not get.

Armrest controller on my seat 35D and nextbooennseat 35E did not work right. Hard to press buttons to recognize and 35D had constantnpressure either upmost down somit was nearly impossible to make selections. .

I flew with my dog and had already purchased my dog’s ticket. Even that morning I had called costumer service to insure that my husband and I had seats together since the website was giving me an error when choosing our seats and the representative mentioned our dog. I showed up early to the airport and when I got to the gate and we started boarding I was help back and told that I was supposed to have a yellow tag and that I should have checked in at the counter for them to give me that tag. I was not aware of this, the representative on the phone did not say anything. Nor did I see it anywhere in the checking process online, so if you travel with a pet and are not checking in luggage, just know that you still have to go to the check in counter when arriving at the airport unless you want to be the last one to board and not have room for your carry on in the overhead bins. Other than that, I had a great experience.

This flight was perfect. No complaints and only the highest regard for the crew and ground staff and how they executed perfectly. I fly a lot with United and would request predictability and transparency in their operations instead of last minute changes.

This is for UA2274 from Houston to Sacramento. The flight was delayed arriving due to mechanical issues so we left about 3 hours later than scheduled. When boarding the plane the temperature inside was excessive - likely close to 100. Pilot apologized and said it was going to improve at altitude, which it did. But before that I honestly thought there might have been more delays removing passengers made ill from the heat. We were delayed leaving due to another mechanical issue. There was not water on the plane due to a panel that was not secured. They did that quickly, but the combination of mechanical issues was rather disturbing and did not reflect well on United.

United sent me a mileage plus number last year but that number is invalid so I can’t use it to check into flights or collect mileage. There is human to speak about the problem, only computers who keep asking me if I am using the correct email. It’s so frustrating and I cannot resolve it.

A little late at the start but all worked out well.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

I appreciated that it was on time, safe and professional. I didn’t like that I wasn’t in a place where I had a window at my window seat. It would have been nice to know that in advance. If it was mentioned in the ticketing, I didn’t notice it.

I have a gluten allergy so didn't have any food

Baggage handling poor. Second time this has happened. My bag went to San Francisco instead of Fiji. No apology. Luckily Nadi airport staff are fantastic. My bag arrived in Fiji the next day.

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

Flight delayed and missed connection. Rescheduled flight cancelled after 6 hrs wait. Rerouted thru ORD, flight cancelled, overnight stay in ORD. Still in the air on new flight!

Delayed delayed delayed and no offer for food or vouchers

A couple ladies from the crew were so rude and nasty. Thought they were mad at having to be there especially if you asked a question. This will make me think twice next time if I book a flight with you.

Everything you need to know for your flight from Des Moines to San Antonio

Information on your arrival and departure airports