DSM - SAT

$122 Find Cheap Flights from Des Moines to San Antonio - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$281
Typical prices: $354-$551
Southwest
Fri 12/7Mon 12/10
DSM - SAT • 1 stop
Cheapest one-way
$122
Typical prices: $182-$388
Frontier
Mon 12/10
DSM - SAT • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and San Antonio. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
April
Cheapest • 22% price drop
March
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Denver Intl (DEN)
Cheapest • Avg $436 (round-trip)
Dallas/Fort Worth (DFW)
Shortest trip • 4h 35m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Antonio!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to San Antonio (DSM-SAT)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to San Antonio

Mon, Dec 7 - Thu, Dec 10
Southwest Logo
3:25 pm - 11:45 pmDSM  Des Moines-SAT San Antonio
8h 20m1 stop Chicago Midway
Southwest Logo
2:40 pm - 10:05 pmSAT  San Antonio-DSM Des Moines
7h 25m1 stop Chicago Midway
$281Southwest
Tue, Dec 8 - Thu, Dec 10
Delta Logo
2:58 pm - 10:19 pmDSM  Des Moines-SAT San Antonio
7h 21m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:16 am - 10:53 amSAT  San Antonio-DSM Des Moines
5h 37m1 stop Atlanta Hartsfield-Jackson
$281Delta
Thu, Dec 3 - Mon, Dec 7
United Airlines Logo
2:56 pm - 9:26 pmDSM  Des Moines-SAT San Antonio
6h 30m1 stop Houston George Bush Intcntl
United Airlines Logo
5:45 pm - 10:21 pmSAT  San Antonio-DSM Des Moines
4h 36m1 stop Houston George Bush Intcntl
$281United Airlines
Mon, Dec 14 - Thu, Dec 17
United Airlines Logo
2:56 pm - 9:26 pmDSM  Des Moines-SAT San Antonio
6h 30m1 stop Houston George Bush Intcntl
United Airlines Logo
5:58 pm - 10:29 pmSAT  San Antonio-DSM Des Moines
4h 31m1 stop Houston George Bush Intcntl
$281United Airlines
Mon, Dec 7 - Thu, Dec 10
Southwest Logo
3:25 pm - 11:45 pmDSM  Des Moines-SAT San Antonio
8h 20m1 stop Chicago Midway
Southwest Logo
12:50 pm - 8:50 pmSAT  San Antonio-DSM Des Moines
8h 00m2 stops Houston Hobby Denver Intl
$286Southwest
Thu, Dec 3 - Mon, Dec 7
Southwest Logo
3:30 pm - 11:45 pmDSM  Des Moines-SAT San Antonio
8h 15m1 stop Chicago Midway
Southwest Logo
1:00 pm - 8:50 pmSAT  San Antonio-DSM Des Moines
7h 50m2 stops Dallas Love Field Denver Intl
$286Southwest
Fri, Nov 27 - Tue, Dec 1
American Airlines Logo
5:23 am - 9:48 amDSM  Des Moines-SAT San Antonio
4h 25m1 stop Dallas/Fort Worth
American Airlines Logo
5:37 pm - 11:23 pmSAT  San Antonio-DSM Des Moines
5h 46m1 stop Dallas/Fort Worth
$301American Airlines
Fri, Nov 27 - Tue, Dec 1
American Airlines Logo
7:16 pm - 12:06 amDSM  Des Moines-SAT San Antonio
4h 50m1 stop Dallas/Fort Worth
American Airlines Logo
2:03 pm - 6:27 pmSAT  San Antonio-DSM Des Moines
4h 24m1 stop Dallas/Fort Worth
$316American Airlines
Fri, Dec 11 - Fri, Dec 18
Delta Logo
6:53 pm - 12:35 amDSM  Des Moines-SAT San Antonio
5h 42m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:29 pm - 9:31 pmSAT  San Antonio-DSM Des Moines
7h 02m1 stop Minneapolis St Paul
$370Delta
Wed, Nov 11 - Sun, Nov 15
Multiple Airlines Logo
2:45 pm - 9:34 pmDSM  Des Moines-SAT San Antonio
30h 49m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
10:29 pm - 7:35 pmSAT  San Antonio-DSM Des Moines
21h 06m2 stops Las Vegas Harry Reid Intl Denver Intl
$468Multiple Airlines
Booking Insights

Price, demand and travel trends for Des Moines to San Antonio flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to San Antonio?

Round-trip flights from Des Moines to San Antonio typically range from $354 to $551. The lowest price found in the past 5 days was $281, on Southwest.

What's the cheapest day of the week to fly from Des Moines to San Antonio?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Des Moines to San Antonio. It’s 11% cheaper than the average day, while Sunday is the most expensive, with prices 47% higher.

What’s the cheapest month to fly from Des Moines to San Antonio?

•April is the cheapest month to fly from Des Moines to San Antonio at $316 round-trip.
•June ($760) and March ($636) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 140% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Des Moines to San Antonio flights

Low season

August

Cheapest flight

$122
Beat the crowds with an average 56% drop in travelers.
The most popular month to fly with an average 31% increase in travelers.
One-way flight from Des Moines to San Antonio

When to book flights from Des Moines to San Antonio

Are your dates flexible? Find out the best times to travel from Des Moines to San Antonio based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to San Antonio flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to San Antonio?

    Two cabin classes are available on flights from Des Moines to San Antonio:

    • Economy Class
    • First Class

  • How long is a flight from Des Moines to San Antonio?

    A nonstop flight from Des Moines to San Antonio takes 00m, covering 872 miles.

  • Do I need a passport to fly from Des Moines to San Antonio?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Des Moines to San Antonio flight?

    Round-trip flights from Des Moines to San Antonio range from $354 to $551, with an average of $405 over the past 12 months. Anything below $354 counts as a good deal.

  • Have flight prices from Des Moines to San Antonio changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $281 to $935. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Des Moines to San Antonio looking right now?

    One-way fares from Des Moines to San Antonio are currently in line with typical prices for this route. Average one-way fares are about $221.

  • What car rental options are available at San Antonio Airport (SAT)?

    San Antonio Airport (SAT) hosts 5 major car rental companies, with daily rates averaging $53 for economy cars. Top options include:

    • Europcar
    • Fox
    • Dollar
    • Hertz
    • Alamo

  • Which airports can I use when flying from Des Moines to San Antonio?

    Flights from Des Moines to San Antonio usually depart from Des Moines (DSM) and arrive at San Antonio (SAT).

  • Which airports do connecting flights from Des Moines to San Antonio pass through?

    One-stop flights from Des Moines to San Antonio most commonly connect through:

    • Dallas/Fort Worth (DFW) - 58% of one-stop connections
    • Houston George Bush Intcntl (IAH) - 27% of one-stop connections
    • Denver Intl (DEN) - 8% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 5% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to San Antonio?

    Yes. Flexible dates can save you up to 40% on flights from Des Moines to San Antonio. Tuesday is the cheapest departure day at $361 round-trip on average, while Sunday is the most expensive at $597, a difference of $236.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Des Moines to San Antonio?

    Flying via Dallas/Fort Worth (DFW) gives the shortest average 1-stop total travel time at 4h 35m, compared with 4h 45m via Houston George Bush Intcntl (IAH) and 5h 41m via Minneapolis St Paul (MSP).

  • What popular places can I visit in San Antonio?

    Some of the most popular sights in San Antonio are San Antonio River Walk, SeaWorld San Antonio and Alamodome. These are among the most viewed places in San Antonio on KAYAK.

Your guide to booking Des Moines to San Antonio flights

Get tips on when to book, when to fly and what to know before your trip.

More options for your flight from Des Moines to San Antonio

Complete your trip to San Antonio with a hotel stay or car rental

Car rentals in San Antonio
Hotels in San Antonio
Vacations in San Antonio