DSM - SAN

$128 Find Cheap Flights from Des Moines to San Diego - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$253
Typical prices: $351-$494
Multiple Airlines
Fri 9/28Mon 10/1
DSM - SAN • 2 stops
Cheapest one-way
$128
Typical prices: $175-$321
Frontier
Fri 11/2
DSM - SAN • 1 stop
Nonstop flights
There are currently no direct flights between Des Moines and San Diego. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 15 weeks in advance save around 56% compared to booking last minute.
Insights
Insights
When to travel
Cheapest • 13% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $347 (round-trip)
Shortest trip • 5h 37m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Diego!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to San Diego (DSM-SAN)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to San Diego

Mon, Sep 28 - Thu, Oct 1
Multiple Airlines Logo
9:31 pm - 6:19 pmDSM  Des Moines-SAN San Diego
22h 48m2 stops Las Vegas Harry Reid Intl San Francisco
Multiple Airlines Logo
9:03 pm - 10:57 amSAN  San Diego-DSM Des Moines
11h 54m1 stop Las Vegas Harry Reid Intl
$253Multiple Airlines
Mon, Sep 28 - Thu, Oct 1
Multiple Airlines Logo
9:31 pm - 4:59 pmDSM  Des Moines-SAN San Diego
21h 28m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
9:03 pm - 10:57 amSAN  San Diego-DSM Des Moines
11h 54m1 stop Las Vegas Harry Reid Intl
$271Multiple Airlines
Mon, Oct 19 - Mon, Oct 26
Frontier Logo
8:25 pm - 3:58 pmDSM  Des Moines-SAN San Diego
21h 33m1 stop Denver Intl
Frontier Logo
6:25 am - 7:30 pmSAN  San Diego-DSM Des Moines
11h 05m1 stop Denver Intl
$274Frontier
Sun, Sep 27 - Mon, Sep 28
Frontier Logo
11:29 am - 11:51 pmDSM  Des Moines-SAN San Diego
14h 22m1 stop Denver Intl
Frontier Logo
6:25 am - 7:33 pmSAN  San Diego-DSM Des Moines
11h 08m1 stop Denver Intl
$302Frontier
Wed, Oct 21 - Sat, Oct 24
American Airlines Logo
2:30 pm - 6:17 pmDSM  Des Moines-SAN San Diego
5h 47m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
10:40 pm - 8:56 amSAN  San Diego-DSM Des Moines
8h 16m1 stop Chicago O'Hare Intl
$355American Airlines
Tue, Sep 29 - Mon, Oct 5
American Airlines Logo
5:30 am - 8:56 amDSM  Des Moines-SAN San Diego
5h 26m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
4:29 pm - 11:45 pmSAN  San Diego-DSM Des Moines
5h 16m1 stop Phoenix Sky Harbor Intl
$355American Airlines
Wed, Jan 20 - Sat, Jan 23
United Airlines Logo
1:45 pm - 5:10 pmDSM  Des Moines-SAN San Diego
5h 25m1 stop Denver Intl
United Airlines Logo
11:20 am - 8:32 pmSAN  San Diego-DSM Des Moines
7h 12m1 stop Denver Intl
$355United Airlines
Tue, Oct 27 - Sat, Oct 31
United Airlines Logo
5:12 pm - 8:36 pmDSM  Des Moines-SAN San Diego
5h 24m1 stop Denver Intl
United Airlines Logo
6:45 am - 4:07 pmSAN  San Diego-DSM Des Moines
7h 22m1 stop Denver Intl
$355United Airlines
Mon, Dec 7 - Thu, Dec 10
Southwest Logo
6:30 pm - 9:50 pmDSM  Des Moines-SAN San Diego
5h 20m1 stop Denver Intl
Southwest Logo
10:55 am - 8:45 pmSAN  San Diego-DSM Des Moines
7h 50m2 stops Phoenix Sky Harbor Intl Denver Intl
$360Southwest
Tue, Oct 6 - Tue, Oct 27
Southwest Logo
6:35 pm - 10:05 pmDSM  Des Moines-SAN San Diego
5h 30m1 stop Denver Intl
Southwest Logo
10:50 am - 8:40 pmSAN  San Diego-DSM Des Moines
7h 50m2 stops Las Vegas Harry Reid Intl Denver Intl
$360Southwest
Booking Insights

Price, demand and travel trends for Des Moines to San Diego flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Des Moines to San Diego with more confidence.

What's the cheapest day of the week to fly from Des Moines to San Diego?

Monday is the cheapest day of the week to fly from Des Moines to San Diego, it is 10% cheaper than the average day. Sunday is the most expensive day with flight prices 16% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Des Moines to San Diego?

  • October is the cheapest month to fly from Des Moines to San Diego at $352 round-trip.
  • December ($485) and July ($466) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 37% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Des Moines to San Diego the cheapest?

Flights from Des Moines to San Diego are cheapest 15 weeks before departure. Booking in this window typically costs about 56% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Key details for Des Moines to San Diego flights

Low season

August

Cheapest flight

$128
Best time to beat the crowds but there is an average 6% increase in price.
Most popular time to fly with an average 11% increase in price.
Flight from Des Moines to San Diego

When to book flights from Des Moines to San Diego

Are your dates flexible? Find out the best times to travel from Des Moines to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to San Diego flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Where can I park at DSM before my flight to San Diego?

    The Long-Term Premium and Long-Term Parking Lots are close enough that you can walk to the terminal. However, the more affordable options, the Blue Lot Economy 2, the Green Lot Economy 3, and the Gray Lot Economy 4, are not within walking distance. But you can take a free shuttle from the Economy Lots to the terminals. At DSM, you cannot reserve parking in advance, but the homepage on the DSM website keeps track of how much space is available in each lot and the Live Shuttle Tracker tells you when the next shuttle is coming.

  • Does DSM provide facilities for nursing moms?

    Yes. There is a Mamava lactation suite located just after the TSA checkpoint near the DSM police desk. Regardless of which concourse you're going to, everyone passes through the same security checkpoint in the main terminal. Each freestanding Mamava unit contains a fold-down table, bench seating on either side, a USB port, an electrical outlet, a coat hook, and a mirror.

  • Does SAN have a military lounge?

    Yes. The USO at SAN is in Terminal 2, landslide. If you are traveling soldier or a member of a military family who wants to relax, regroup, or refresh after your flight from Des Moines, you can visit the USO and enjoy its benefits and facilities free of charge. Amenities include showers, comfortable seating, refreshments, TV, unlimited domestic calls, and much more.

  • Where can I pick up my rental car at SAN?

    All car rental companies are located in a separate building outside the SAN airport. At the Arrivals curb, you can catch a free shuttle to whichever car rental agency you need to go to. Some car rental agencies at San Diego Airport include Avis, Enterprise, Budget, Alamo, Hertz, Firefly, National, and more.

  • Which airports can I use when flying from Des Moines to San Diego?

    Flights from Des Moines to San Diego usually depart from Des Moines (DSM) and arrive at San Diego (SAN).

  • What cabin classes can I book on flights from Des Moines to San Diego?

    Two cabin classes are available on flights from Des Moines to San Diego:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Des Moines to San Diego pass through?

    One-stop flights from Des Moines to San Diego most commonly connect through:

    • Denver Intl (DEN) - 52% of one-stop connections
    • Phoenix Sky Harbor Intl (PHX) - 31% of one-stop connections
    • Las Vegas Harry Reid Intl (LAS) - 5% of one-stop connections
    • Minneapolis St Paul (MSP) - 5% of one-stop connections

    Denver Intl (DEN) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Des Moines to San Diego?

    Yes. Being flexible with your travel dates can save you up to 23% on the Des Moines to San Diego route. Monday is the cheapest departure day at $366 round-trip on average, while Sunday is the most expensive at $471, a difference of $105. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in San Diego?

    Some of the most popular sights in San Diego are Gaslamp Quarter, San Diego Convention Center and SeaWorld San Diego. These are among the most viewed places in San Diego on KAYAK.

  • How expensive are last-minute Des Moines to San Diego flights?

    Last-minute fares on this route - booked within 2 weeks of departure - run 89% above the route average of $403. Book 15 weeks before departure for the lowest fares.

  • How long is a flight from Des Moines to San Diego?

    A nonstop flight from Des Moines to San Diego takes 0h 00m, covering 1,425 miles.

  • Do I need a passport to fly from Des Moines to San Diego?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Des Moines to San Diego changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $253 to $1,471. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Des Moines to San Diego looking right now?

    One-way fares from Des Moines to San Diego are currently lower than usual. Average one-way flight prices are about $188, which is 20% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Des Moines to San Diego?

    Flying via Phoenix Sky Harbor Intl (PHX) gives the shortest average 1-stop total travel time at 5h 37m, compared with 5h 54m via Las Vegas Harry Reid Intl (LAS) and 6h 22m via Dallas/Fort Worth (DFW).

  • What is the time difference between Des Moines and San Diego?

    San Diego is 2 hours behind Des Moines (Pacific Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at San Diego Airport (SAN)?

    San Diego Airport (SAN) hosts 5 major car rental companies, with daily rates starting from around $14 for economy cars. Top options include:
    · Dollar
    · Payless
    · Europcar
    · Thrifty
    · Fox

  • How much should I expect to pay for a Des Moines to San Diego flight?

    Round-trip flights from Des Moines to San Diego range from $351 to $494, with an average of $403 over the past 12 months. Anything below $351 counts as a good deal.

Your guide to booking Des Moines to San Diego flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Monday departure instead of Sunday. On this route, Monday flights average $366 - about $105 less than Sunday (22% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 15 weeks before you fly. On this route, that window historically saves about 56% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Des Moines to San Diego trip for October. Fares historically average $352 round-trip in that month - typically $133 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Diego Airport.
    - Courtyard by Marriott San Diego Downtown Little Italy
    - Bay Club Hotel & Marina
    - Sheraton San Diego Resort
  • Located virtually in the center of the state of Iowa, the Des Moines International Airport (DSM) serves as a focus city for Allegiant Air. The San Diego International Airport (SAN), located on the Pacific coast in California just north of the Mexican border, is a hub for Southwest, Alaska Airlines, and other smaller airlines.
  • Though is unlikely you will find a direct flight from Des Moines to San Diego, you can find one-stop flights on several airlines, such as United, often with a stop in Denver. Southwest, American, and Delta also have one-stop flights with layovers in cities such as Dallas, Phoenix, Minneapolis, in Atlanta. United, American, and Delta are among the airlines offering two-stop flights as well.
  • There is one animal relief area at DSM located outside the terminal. So, remember to make sure that your service animal or your pet goes to the bathroom before you enter the airport and go through security. This animal relief area is north of the Skywalk next to the parking garage.
  • A baggage claim at SAN, you can find the service Traveler’s Aid. Open every day from 8 am to 11 pm, Travelers Aid helps passengers who are stranded or distressed. For example, if your accommodation plans have fallen through, if your money has been lost or stolen, or if you need transportation assistance, Travelers Aid is there to help.
  • If you feel stiff and sore after your flight from Des Moines, consider getting a massage at one of the two Be Relax Spa locations at the San Diego Airport. There is one spa location at Gate 26 in Terminal 2 and another location atG ate 36 in Terminal 2. These spas are open daily from 7 am to 8 pm.

More options for your flight from Des Moines to San Diego

Complete your trip to San Diego with a hotel stay or car rental