$63 Find Cheap Flights from Detroit to St. Louis - Compare and Save

Your flight ticket price will generally be cheaper if you fly to St. Louis on a Saturday and more expensive on a Sunday. On your return trip to Detroit, you should consider flying back on a Friday, and avoid Sundays for better deals.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to St. Louis is August, where tickets cost $262 (return) on average. On the other hand, the most expensive months are April and February, where the average cost of round-trip tickets is $445 and $427 respectively.

No, with an average price for the route of $304, prices are generally cheapest when you fly direct.

To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to St. Louis, you should book around 4 weeks before departure, which saves you about 46% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 10 weeks before departure.

In the past 5 days, the cheapest round-trip tickets from Detroit to St. Louis were found on Frontier ($131) and American Airlines ($197).

There are 2 airlines that fly nonstop from Detroit Metropolitan Wayne County Airport to St. Louis. They are Delta and Southwest. The cheapest airline for this route is Delta, with the best round-trip deal found costing $177. On average, the best prices for this route can be found at Southwest.

Chicago (ORD) is the top choice – 36% of KAYAK users who clicked on 1-stop flights from Detroit to St. Louis picked an itinerary connecting there.

Flights via Denver (DEN) offer the most affordable fares, with an average round-trip price of $193.

Consider flying via Chicago (MDW) for the shortest journey. The average one-way travel time for flights connecting there is 4h 40m.

If you prefer a quick connection, Chicago (MDW) often has the shortest layovers from Detroit to St. Louis, with an average of 2h 00m.

There are 4 cabin class options for the route. These are First, Business, Economy and Prem Economy. Perform a search on KAYAK to find the latest prices and availability for all cabin fares, which differ across airlines.

Each day, there are between 5 and 6 nonstop flights that take off from Detroit Metropolitan Wayne County Airport and land in St. Louis, with an average flight time of 1h 37m. The most common departure time is 6:00 am and most flights take off in the morning. Each week, there are 41 flights. The most frequent day of departure is Monday, when 15% of all weekly flights depart. The fewest flights depart on a Saturday.