$547 Find Cheap Flights from Europe to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Panama City departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Europe to Panama City

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Europe to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Europe to Panama City

Mon, Apr 20 - Mon, Apr 27
United Airlines Logo
9:30 am - 9:59 pm
LHR
-
ECP
18h 29m
2 stops
United Airlines Logo
4:57 pm - 11:35 am
ECP
-
LHR
12h 38m
1 stop
$688United Airlines
Tue, Apr 21 - Tue, Apr 28
United Airlines Logo
9:30 am - 9:59 pm
LHR
-
ECP
18h 29m
2 stops
United Airlines Logo
6:30 am - 6:45 am
ECP
-
LHR
18h 15m
2 stops
$689United Airlines
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
9:20 am - 10:00 pm
FRA
-
ECP
19h 40m
2 stops
American Airlines Logo
2:33 pm - 1:50 pm
ECP
-
FRA
16h 17m
2 stops
$700American Airlines
Sat, Apr 4 - Tue, Apr 14
Delta Logo
6:00 am - 11:04 pm
IST
-
ECP
25h 04m
2 stops
Delta Logo
7:05 am - 1:20 am
ECP
-
IST
34h 15m
2 stops
$701Delta
Thu, Jun 25 - Mon, Jun 29
American Airlines Logo
6:40 am - 10:36 pm
FRA
-
ECP
22h 56m
2 stops
American Airlines Logo
3:14 pm - 10:20 pm
ECP
-
FRA
24h 06m
2 stops
$708American Airlines
Mon, Apr 20 - Mon, Apr 27
Virgin Atlantic Logo
9:20 am - 7:36 pm
LHR
-
ECP
16h 16m
1 stop
Virgin Atlantic Logo
9:21 am - 6:25 am
ECP
-
LHR
15h 04m
1 stop
$710Virgin Atlantic
Mon, Apr 13 - Sun, Apr 19
Virgin Atlantic Logo
11:15 am - 9:22 pm
LHR
-
ECP
16h 07m
1 stop
Virgin Atlantic Logo
6:46 pm - 7:15 am
ECP
-
LHR
30h 29m
1 stop
$717Virgin Atlantic
Tue, Apr 21 - Tue, Apr 28
Multiple Airlines Logo
12:55 pm - 9:58 pm
LHR
-
ECP
15h 03m
1 stop
Multiple Airlines Logo
1:08 pm - 6:50 am
ECP
-
LHR
11h 42m
1 stop
$720Multiple Airlines
Tue, Apr 21 - Tue, Apr 28
Delta Logo
11:45 am - 11:12 pm
LHR
-
ECP
17h 27m
2 stops
Delta Logo
5:10 pm - 1:15 pm
ECP
-
LHR
14h 05m
1 stop
$725Delta
Sun, Apr 5 - Sun, Apr 12
Multiple Airlines Logo
1:05 pm - 11:04 pm
MAD
-
ECP
16h 59m
2 stops
Multiple Airlines Logo
6:43 pm - 4:45 pm
ECP
-
MAD
15h 02m
2 stops
$996Multiple Airlines
Useful Info

Good to know

Low seasonFebruary
Cheapest flight$547
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 28% increase in price.
Flight from Madrid to Panama City

FAQs for booking flights from Europe to Panama City

  • How does KAYAK find such low prices on flights from Europe to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Europe to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Europe to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Europe is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Europe to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Europe with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Europe to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Europe up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Europe to Panama City

 
Need help choosing which airline to fly with from Europe to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Virgin AtlanticOverall score based on 680 reviews
7.7Boarding
7.6Entertainment
8.2Crew
7.3Comfort
6.9Food
Airline reviews

My seat 3G did not go down fully and the buttons were not working properly

8.0 ExcellentAditya, Feb 2026
LHR - JFK
Read more Virgin Atlantic reviews

My seat 3G did not go down fully and the buttons were not working properly

Food has been disappointing in both legs of flight to india

Great staff great experience, made a 2 hour delay very bearable

Great staff, great experience, made a 2 hour delay very bearable

Food was the worst I’ve had on a VA flight. Normally it’s a lot better

I was my pleasure to fly virgin on my birthday for my first solo trip ever 🫶🏼

These are one of the older seat arrangements facing away from the windows! Not particularly convenient sets. No storage spaces. NO COAT HANGING HOOKS. Inconvenient business class seat compared to any other airlines of similar class. Staff are excellent! Extremely professional, friendly. Food is good too.

Overall, flight was excellent but check in was very slow for Premium Economy. Economy queue was shorter but we weren't allowed to use it.

The staff was not very polite but the flight was very very nice and comfortable and the entertainment was great

Great crew - old style upper class seats on the older fleet now feels dated

Traveling to a place near Panama City?

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Freeport

Everything you need to know for your flight to Panama City

Information on the airport you'll fly into in Panama City

Panama City (ECP)