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Find cheap flights from Florida Keys to South Carolina from $41

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Florida Keys to South Carolina departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Thu 5/23
Thu 5/30

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Low season

January

High season

April

Cheapest flight

$41
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Miami to Charlotte

FAQs for booking flights from Florida Keys to South Carolina

  • How does KAYAK find such low prices on flights from Florida Keys to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South Carolina from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South Carolina with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South Carolina from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top 5 airlines serving from Florida Keys to South Carolina

 
Need help choosing which airline to fly with from Florida Keys to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
Copa AirlinesOverall score based on 2902 reviews
7.7comfort
8.1boarding
7.4food
8.3crew
7.2entertainment
Airline reviews

Captain and Crew were excellent. The Boeing 737-800 was showing its age. In flight entertainment system was sluggish and my Business Class seat on the outbound flight had some mechanical issues. Only real problem was the location of the Gate in Panama PTY. It was a 40 minute hike from Security to the Gate. There should have been some sort of warning about the distance.

10.0 ExcellentAnonymous, Mar 2024PTY - BWI
Read more about Copa Airlines reviews

Captain and Crew were excellent. The Boeing 737-800 was showing its age. In flight entertainment system was sluggish and my Business Class seat on the outbound flight had some mechanical issues. Only real problem was the location of the Gate in Panama PTY. It was a 40 minute hike from Security to the Gate. There should have been some sort of warning about the distance.

landed in panama it was in terminal one. We had to take a bus to terminal two for customs. Then back to terminal one. It was very frustrating. Then, on the way back from panama it was the same situation. We had to go back and forth between terminals to check in and drop our bags and then to board. When we were leaving, we had to wait in line for the boarding area and go through another gate security process. They told the bottles of water and coffee were bought while in line in the airport after we passed the main security. Ridiculous (and expensive). A much better communication system is needed.

This was my first time flying Copa but I'll definitely be back! Great service, professional agents, and delicious food for a fair price. Thanks for a great trip!

Horrible experience from start to end. Copa costumer service is non existent. They treat you bad. Everybody tells you different information. We didn’t received our luggage in the 1 day stop we did even we they said if was not going to be a problem. They didn’t respect the seats that we had and spread our family leaving in between of two big people who didn’t leave any space for me and crush me from side to side. I’ll never recommend Copa to anybody.

No cumpli mencionado trayecto por reasignacion de Copa Pero extraviaron mis maletas por su culpa

I was fortunate enough to have an entire row to myself and that was the highlight. Unfortunately, the flight was really turbulent which had no impact on how effective the crew was. However, I am disabled and should have boarded the flight first, but that wasn't the case. They also decided to take my bag at the gate because I had one too many and upon my picking it up at JFK it along with my rollator had been damaged. I am a vegan so the didn't have a proper meal for me and I was unable to view the entertainment because I didn't receive a set of headphones and if I needed to supply my own I wasn't made aware of that either. The crew was great, but overall everything was pretty lackluster.

LOCKED MY BAG WITHOUT CONSENT. Had to have my zippers cut upon arrival in Costa Rica.

Pros: "The seats in economy were confortable. The best thing was Copa gave us seats in the second line and my family traveled together."
Cons: "Coffe service could better the experience"
Cons: "Sure. I had booked a two week vacation in Brazil. All hotels, car rental and guides booked. Copa changed my fligjt at the last minute and out of the 14 days vacatipn I had in Brazil, they would have me spend 6 days in Panama City!!! Lost of small fortune with hotels, car rentals amd had to buy another ticket with Latam. They are a scam!!"
Cons: "Due the COVID-19 El Salvador closed its boarders, leaving me unable to fly. I have sent two emails, called and spoke to a customer service representative who treated me unprofessionally and rude. After that I have been calling numerous times with a wait of over 25 minutes each time and I still have to answer from you as a company. I am extremely disappointed and want an answer soon."

That flight was smooth, and staff we courteous. it was a full flight so very tight. The boarding through security was not properly controlled. it was rushed and the scanning process for our bags, etc. was pilling up at the other end with no time to empty our belonging my personal items almost toppled over on the floor if i hadn't caught it rapidly. Was it just that time, or always like this - cant say. other than that all else was fine.

Boarding was friendly and quick. While the plane model was older with no live tv, the entertainment was full of movies and tv shows. All food was available. Pilots were very communicative with status of the flight. Flight landed on time.

It was terrible because the flight was delayed for 3 hours.

Crowded flight, but upbeat and kind crew. Pilot greeted us at door, flight attendant thanked a number of “special” passengers for their business, another addressed an eight-year old boy as “young man.” United obviously trying to up their game, but though all of that is nice and notable, flying still feels like moving along a human assembly line, being herded into one small space after another (boarding areas with too few seats, planes with limited personal space, shuttles (IAD) packed too full.

Did not like the seat spacing. The seat was very narrow and tight.

United domestic flight was better than international flight. There was no switch to control Ac In international united flight. Food was also average, Air canada food was much better than united.

The flight was clean and on time, the crew were all very nice and we got the seats we booked. Plenty of food and beverages. The seats are too close so it’s very difficult to try and sleep comfortably.

Any flight that gets from point A to B with no drama is excellent.

They cancelled our flight at the last minute due to mechanical issues. Rather, they “delayed” it till the next morning. A pain in the neck when traveling with two young children. Crew was really nice, which made up for it somewhat. This is the second flight from delta that was cancelled this year. Definitely going to fly another airline when possible

Boarding did not give first class prefernce, ahead of othwr group passengers. Cabin crew were ok, food was mediocre.

The Flight attendant had an attitude and didn't allow anyone any time to prepare for landing despite being absent throughout the entire trip

Horrible people at the gate, they force me to check in my carry on, even thought no one behind me has to do it. I had to get out of the airport in NY to get my bag and go thru security again on my way to Honk Kong. The worst part is the employee threatened me with loosing the flights if don’t comply.

Delayed flight, few announcements with information, no comps, cluster f boarding because zones weren’t spread out and announced loud and repeatedly, staff did their job -nothing more nothing less, annoying kids were speaking and kicking the heck out of the back of my seat and parents weren’t willing to parent… so another typical day of air travel in the US.,

Flight was delayed until Next day as crew timed out

The flight was great until towards the end when the flight attendant read an excessively long commercial for purchasing an american airlines credit card. The worst part is that we are doing a lot of traveling this year so i was actually interested in getting the credit card, but I was so annoyed with the long commercial that I completely dismissed the flight attendant bringing around the information. Next time, keep the sales pitch to 10 seconds and then pass around the brochures!!

I was able to get on standby with relative ease

6 plus hour delay with no explanation. No wheelchairs to transport us on arrival. Very disappointed.

Me and my husband experienced very bad in American Airlines. We missed our flight going to Doha. The American Airlines was delayed we arrived already 10:27pm. Supposed to be 9:40 pm. So what they did they rebooked our flight and they gave us a hotel. When we arrived at the hotel the front desk said it was fully booked already. Oh my gosh! I said why did you accept the booking if it's fully booked. The guy said that's American Airlines they just book even it's already full. That's 2am already, we have nothing to do so, we decided to go another hotel. We pay the room, food and taxi. Pls give an action on this matter. Refund our expenses and give us more compensation. Not only our room, food, taxi but also our efforts, tiredness looking for a room that can accommodate us.

Food choice is limited, entertainment better than average, seat leg room terrible

Horrible. Flight was delayed and very bumpy. I was super unhappy

I paid just under 200 for flight and luggage, then paid 200 to change the flight, then paid 100 for a carry on. Then the cancelled the flight. Of the 500 I spent they refunded 250. I bought a delta flight for 270 never flew with spirit, but spirit kept 250, not even refunding the 100 for the carry on though they cancelled the flight (for weather on a day with only a slight rain ).

Flight attendants heavily pushed their affinity credit card. Very annoying

On time and fast. Overall it was a pleasant experience.

The seat are terrible. Don’t even think of sleeping on a Spirit flight. The kids that run the plane aka flight attendants are pretty rude and straight forward. They get the job done but without class.

I had a death in my family and booked my flight on Spirit. My flight was cancelled the morning of my flight, no explanation, no help to rebook, nobody to talk to. The next available flight was 2days later !!!! Terrible airline, will NEVER fly with them again!

Flight was canceled. Knew there was weather, and were notified of 20 min delayed, and then suddenly canceled. Next reschedule was for 2 days. No help other than to refund. Thankfully full refund and appreciate that. I appreciate discounted airline but felt they could've done more for customer inconvenience.

They seemingly have no respect for their customers, on any level. Avoid flying spirit, they will bump you to another flight without thinking twice so they can sell your seat, no joke.

Flying on Spirit Airline is a penny-pinching beat down.

Seats are very small and extremely hard. Too close together. The person next to me had average shoulders and was very far into my 'space'.

Bag self drop off was terrible! No staff there to help. Almost missed my flight. Would never check a bag in with Spirit again.

Crew members are very rude and not cooperate with passengers.

30 minute delay due to boarding and settling of a family.

I am HIGHLY unhappy with the amount of money I spent on the flight. Paid in advance only to find the flight at a discount price a week or so before the flight. I will not fly frontier again and have bad mouthed your business since to anyone I have spoken with about flying (which has been many a people). Crew was mediocre and instead of moving me to a spot where I could gain some leg room they sat their flight attendant there. Won’t be flying frontier in the future.

Well, I didn’t have food! So NA wasn’t an option. I’ll be back!

First time flying with Frontier . From buying tickets ,getting boarding pass and boarding plane was super easy. Definitely would fly again with Frontier .

Our flight was on time and unremarkable which I'm grateful for, as it is not the norm traveling these days. Frontier is a low-cost carrier and it really shows when compared to other "normal" carriers. They don't even give you water during the flight. The coach seats are decent, however it was not as clean as it should be. We had crumbs all over the floor by our seats.

They lost my baggage on my connection flight, it’s been 24 hours since I put my claim in and still no update on my bags.

they charge too much when you arrive in the air port

The flight was canceled, then delayed twice, we were moved gates twice. Short staff at the counter and check in. We waited for our flight 9 hours. Will never use Frontier ever again, or Spirit.

The flight was delayed 1 hour. The Seats are the worst most uncomfortable chairs I have ever sat in. I have folding chairs in my Garage that are more comfortable.

Book cheap flights from Florida Keys to South Carolina

Recent round-trip flight deals

5/8Wed
nonstopSpirit Airlines
2h 13mMIA-CLT
5/15Wed
nonstopSpirit Airlines
2h 14mCLT-MIA
$85
5/22Wed
nonstopSpirit Airlines
2h 13mMIA-CLT
5/29Wed
nonstopSpirit Airlines
2h 14mCLT-MIA
$87
5/9Thu
nonstopSpirit Airlines
2h 13mMIA-CLT
5/13Mon
nonstopSpirit Airlines
2h 14mCLT-MIA
$88
5/8Wed
1 stopFrontier
10h 09mMIA-CLT
5/15Wed
1 stopFrontier
6h 56mCLT-MIA
$95
5/18Sat
1 stopFrontier
8h 27mMIA-CHS
5/20Mon
1 stopFrontier
8h 08mCHS-MIA
$98
5/1Wed
nonstopAmerican Airlines
1h 45mMIA-CHS
5/3Fri
nonstopAmerican Airlines
1h 46mCHS-MIA
$137
5/26Sun
nonstopAmerican Airlines
1h 47mMIA-CHS
5/29Wed
nonstopAmerican Airlines
1h 41mCHS-MIA
$141
5/11Sat
1 stopJetBlue
8h 08mMIA-CHS
5/14Tue
1 stopJetBlue
9h 55mCHS-MIA
$275
5/3Fri
1 stopUnited Airlines
6h 47mMIA-GSP
5/7Tue
1 stopUnited Airlines
6h 13mGSP-MIA
$411
5/14Tue
2 stopsUnited Airlines
12h 05mEYW-CLT
5/15Wed
2 stopsUnited Airlines
10h 40mCLT-EYW
$479

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Recent one-way flight deals

5/22Wed
nonstopSpirit Airlines
2h 13mMIA-CLT
$41
4/29Mon
nonstopSpirit Airlines
2h 16mMIA-CLT
$43
5/25Sat
nonstopSpirit Airlines
2h 13mMIA-CLT
$48
5/22Wed
1 stopFrontier
8h 55mMIA-CLT
$55
5/18Sat
1 stopFrontier
9h 45mMIA-MYR
$55
4/29Mon
1 stopAmerican Airlines
4h 25mMIA-CHS
$77
4/30Tue
nonstopAmerican Airlines
2h 09mMIA-CLT
$90
5/20Mon
2 stopsUnited Airlines
26h 52mMIA-GSP
$278
5/18Sat
2 stopsUnited Airlines
31h 59mMIA-CAE
$279
4/28Sun
1 stopJetBlue
6h 41mEYW-CHS
$370

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Last minute flights from Florida Keys to South Carolina

Last minute flight, train and bus deals

4/27Sat
multi-stopSpirit Airlines
24h 19mMIA-CLT
4/29Mon
nonstopSpirit Airlines
2h 08mCLT-MIA
$153
4/27Sat
multi-stop
8h 33mMIA-CLT
4/28Sun
nonstop
2h 08mCLT-MIA
$172
4/26Fri
multi-stopDelta
4h 20mMIA-CHS
4/29Mon
multi-stopDelta
4h 27mCHS-MIA
$185
4/26Fri
nonstopAmerican Airlines
1h 51mMIA-CHS
4/29Mon
nonstopAmerican Airlines
1h 42mCHS-MIA
$187
4/27Sat
multi-stopFrontier
8h 33mMIA-CLT
4/29Mon
multi-stopFrontier
6h 27mCLT-MIA
$188
4/26Fri
multi-stopAmerican Airlines
6h 34mMIA-CHS
4/29Mon
nonstopAmerican Airlines
1h 42mCHS-MIA
$195
4/27Sat
multi-stopFrontier
8h 33mMIA-CLT
4/27Sat
multi-stopFrontier
12h 27mCLT-MIA
$199
4/26Fri
multi-stopDelta
4h 20mMIA-CHS
4/28Sun
multi-stopDelta
4h 17mCHS-MIA
$235
4/24Wed
multi-stopUnited Airlines
8h 51mMIA-GSP
4/29Mon
multi-stopUnited Airlines
15h 36mGSP-MIA
$648
4/26Fri
multi-stopUnited Airlines
22h 36mMIA-GSP
5/1Wed
multi-stopUnited Airlines
6h 39mGSP-MIA
$653

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Flights to South Carolina

Return flight deals:

South Carolina - Florida Keys

Cabin classes:

$381
$373
$348
$39