$77 Find Cheap Flights from Florida Keys to South Carolina - Compare and Save

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Low season

January

Cheapest flight

$77
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from Key West to Charleston

FAQs for booking flights from Florida Keys to South Carolina

  • How does KAYAK find such low prices on flights from Florida Keys to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Florida Keys to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Florida Keys to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Florida Keys to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • Which airlines fly most frequently to South Carolina?

    Florida Keys and South Carolina are connected by different airlines. The airlines that fly that route the most regularly are American Airlines (34 flights per week), GOL (30 flights per week), and Qatar Airways (23 flights per week).

  • How many airports are there in South Carolina?

    There are 6 airports in South Carolina. The busiest airport is Charleston Municipal Airport (CHS), with 40% of all flights arriving there.

  • What is the cheapest month to fly from Florida Keys to South Carolina?

    The cheapest month for flights from Florida Keys to South Carolina is November, when tickets cost $210 (return) on average. On the other hand, the most expensive months are August and January, when the average cost of round-trip tickets is $371 and $296 respectively.

  • How far in advance should I book a flight from Florida Keys to South Carolina?

    To get a below average price on the flight from Florida Keys to South Carolina, you should book around 3 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 12 weeks before departure.

  • How many cities have direct flights to South Carolina?

    From Florida Keys, there are direct flights to South Carolina from 1 city. This city is Miami and there are 99 direct flights each week.

  • How many direct flights to South Carolina are there each day?

    There are around 15 direct flights from within Florida Keys to South Carolina every day. Most flights (62%) depart in the evening.

  • How many direct flights to South Carolina are there each week?

    Each week there are around 99 direct flights from within Florida Keys to South Carolina. The most common day for departures is Thursday, with 19% of flights taking off on this day.

  • How long is the flight to South Carolina?

    An average nonstop flight from Florida Keys to South Carolina takes 5h 13m, covering a distance of 565 miles. The shortest route is Miami (MIA) to Savannah (SAV) with an average flight time of 1h 32m.

  • How many long-haul flights are there to South Carolina each week?

    There are not any long-haul (6-12 hour flight duration) or medium-haul (3-6 hour flight duration) flights to South Carolina. Instead, there are 99 short-haul flights (up to 3 hour flight duration), with the most arriving from Miami.

  • What is the most popular destination in South Carolina?

    Based on KAYAK flight searches, the most popular destination is Charlotte (100% of total searches to South Carolina).

Reviews of the top 4 airlines serving from Florida Keys to South Carolina

 
Need help choosing which airline to fly with from Florida Keys to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8554 reviews
8.5Crew
7.8Entertainment
7.8Comfort
8.1Boarding
7.2Food
Airline reviews

Both legs on the way were smaller planes, each had a mechanical issue causing a delay

4.0 OkayAlexander, Sep 2026
Read more Delta reviews

Both legs on the way were smaller planes, each had a mechanical issue causing a delay

Delayed flight. Dirty seats, dirty seat belts with food stuck on it from previous passengers maybe. No one cleaned the seats or flight.

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

The landing the pilot was very smooth. The flight attendant was kind of rude.The boarding the plane in punta Gorda was not great made us wait out in the heat 😞

My exit seat was very comfortable Coffee was to be purchased but sodas free 😏

This is a no frills, get it done, efficient airline. The seat is a lawn chair. You better bring your own entertainment. If you want something other than water you need to pay for it. But they will get you to your destination quickly, on time, and then they will turn the flight around and go right back where they came from. Reliably. Couple times a week tops. If it fits into your schedule, you can’t get there cheaper or faster.

Allegiant actually impressed me, original inbound flight from PBG was so late they gave us a bird inbound from Des Moines and only left 1h late and gained 40 minutes back in the air. Comfortable flight with no frills but no complaints.

Flight was delayed. Crew was good but hot coffee was not available.

It was cold on the flight. The crew was very pleasant. I didn't order any food. We were delayed due to Captain waiting on maintenance log. He kept us informed though. The flight itself was smooth. I would definitely fly with Allegiant again!

Superb. Staff great. Great flight. As with other airlines, seating too tight and restrictive.

My 90 year old father flew with me. He needed wheel chair assistance and is nearly deaf. The staff was amazing with him.

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

No frills, value airline. This trip was exactly what I expected. The flight was on time departing and arrived ahead of schedule. The crew was very efficient at getting people on and off the plane. I think the carry-on bag charges discouraged most people from bringing one, which led to quicker de-planing. I was careful to only bring a carefully packed personal item that was under the size limit. If you keep in mind that everything costs extra with this airline (including snacks, drinks, and printing boarding passes), and go into this with the right expectations, then all will be well. For the price difference, I would fly this airline again. My flight was only 1 hr. 20 minutes though. Much longer than that and comfort might drive me to another airline. The seats are very basic and don't recline at all.

My flights were all delayed , mostly due to technical issues with AA aircrafts. I had to rebook my trip 4 times . I lost my whole day and finally arrived in LAX around midnight. This was a very bad experience with American airlines , I will always try to avoid flying with them

My flight was delayed close to 10 times over the course of the evening. I was originally scheduled to depart at 7:03 PM but did not leave until 12:33 AM, resulting in over 9 hours spent waiting at the airport. The only explanation provided was that the aircraft kept being swapped, with no clear reasoning as to why. Weather conditions at both DCA and Tampa were clear, so that was not a factor. The only accommodation offered was a $12 food voucher, which was entirely insufficient given the length of the delay. Overall, I was completely unsatisfied with this experience. A delay of this magnitude with no meaningful communication or accommodations is unacceptable, and I would have expected much more from American Airlines in terms of customer care.

if it's a mobile only entertainment experience, please provide a place to hold the device in the back of the seat.

Our flight was delayed to Louisville. What made this worse was they did not have another flight attendant to service the flight. This caused an even longer delay. Then when a flight attendant did show up, she chose to "swap" flights with another flight attendant. Therefore, we had to wait longer for the other flight attendant to come to our flight. This is information that the gate attendant should not have shared. Processes and execution at American are broken. Passengers are feeling it. Fixing this starts at the top of the organization.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

My original flight was cancelled. My replacement flight was delayed over 2 hours. I lost my whole day in NY

Delays were crazy long (over an hour) both for boarding and baggage claim

awful expereince. boarding was a mess and not communicated, then we sat on a hot plane and were at risk of getting kicked off

2 hour delay and a lack of air conditioning on the plane. Not a good combination

First time flying JetBlue and my perception changed. Love it.

Poor, had a 5+ hours delay. Kept sitting in the aircraft with three kids. It was terrible

They cancelled the flight after 5 hours at the airport and the only flight they offered was for the next day with a 7.5 layover in fll. This was not going to work for me as this was only a weekend trip and getting into providence at 10 pm a day later caused me to lose Mo ey on hotels money on airport parking a dog sitter etc. they wouldn’t offer any type of a voucher or anything else. All they did was refund the flight which didn’t help me with all the money in time I lost. I was going to see my very sick father

The flight was delayed. I upgraded to more room. I can't imagine how small the regular seats are I haven't upgraded for my return flight yet.

My checked in luggage cost was $59, almost ticket price. The first 13 rows were empty, but fly attendant did not alow women with little boy change her middle sit, sweet boy was crying, I am so sorry for mother and passengers. At the end of the flight the cabin became impossible cold. Only good was timing of departure and early landing, but it suppose to be normal.

I tried to book a flight with Jet Blue. Your third party company hijacked my attempt with a website that looked like I was booking with Jet Blue. I realized it when I paid. I tried to cancel and was told by a man in India that there were no refunds. $735 stolen, Thanks Kayak!

More options for your flight to South Carolina

Complete your trip to South Carolina with a hotel stay or car rental