CHS

$88 Find Cheap Flights from Florida Keys to Charleston

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Charleston departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Charleston

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Useful Info
Flight Deals

Cheap Flights from Florida Keys to Charleston

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Florida Keys to Charleston that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Florida Keys to Charleston

Fri, Jun 5 - Sun, Jun 7
Breeze Airways Logo
12:07 pm - 8:48 am
EYW
-
CHS
20h 41m
1 stop
Breeze Airways Logo
2:53 pm - 11:27 am
CHS
-
EYW
20h 34m
1 stop
$273Breeze Airways
Wed, Sep 23 - Sat, Sep 26
American Airlines Logo
9:20 pm - 11:05 pm
MIA
-
CHS
1h 45mnonstop
American Airlines Logo
11:18 am - 12:55 pm
CHS
-
MIA
1h 37mnonstop
$277American Airlines
Sat, May 16 - Mon, May 18
Multiple Airlines Logo
10:57 am - 1:44 pm
MIA
-
CHS
26h 47m
1 stop
Multiple Airlines Logo
4:57 pm - 2:44 pm
CHS
-
MIA
21h 47m
2 stops
$280Multiple Airlines
Wed, Sep 23 - Sat, Sep 26
American Airlines Logo
5:30 pm - 7:17 pm
MIA
-
CHS
1h 47mnonstop
American Airlines Logo
5:34 am - 9:11 am
CHS
-
MIA
3h 37m
1 stop
$287American Airlines
Tue, Jun 16 - Tue, Jun 23
Southwest Logo
1:45 pm - 8:40 pm
MIA
-
CHS
6h 55m
1 stop
Southwest Logo
2:10 pm - 9:50 pm
CHS
-
MIA
7h 40m
1 stop
$297Southwest
Sat, Jun 20 - Sat, Jun 27
American Airlines Logo
10:15 pm - 11:59 pm
MIA
-
CHS
1h 44mnonstop
American Airlines Logo
8:09 pm - 9:55 pm
CHS
-
MIA
1h 46mnonstop
$298American Airlines
Sun, May 24 - Wed, May 27
Southwest Logo
7:00 am - 2:30 pm
MIA
-
CHS
7h 30m
1 stop
Southwest Logo
12:00 pm - 9:55 pm
CHS
-
MIA
9h 55m
2 stops
$302Southwest
Mon, Jun 1 - Fri, Jun 5
Multiple Airlines Logo
1:11 pm - 9:37 am
EYW
-
CHS
20h 26m
1 stop
Multiple Airlines Logo
9:25 pm - 1:16 pm
CHS
-
EYW
39h 51m
2 stops
$303Multiple Airlines
Mon, Jun 1 - Fri, Jun 5
United Airlines Logo
2:26 pm - 10:16 am
EYW
-
CHS
19h 50m
2 stops
United Airlines Logo
7:47 pm - 1:30 pm
CHS
-
EYW
17h 43m
2 stops
$845United Airlines
Fri, Aug 21 - Mon, Aug 24
United Airlines Logo
2:20 pm - 2:54 pm
EYW
-
CHS
24h 34m
1 stop
United Airlines Logo
11:08 am - 1:34 pm
CHS
-
EYW
26h 26m
1 stop
$1,169United Airlines
Useful Info

Good to know

Low seasonJanuary
Cheapest flight$88
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 19% increase in price.
Flight from Key West to Charleston

FAQs for booking flights from Florida Keys to Charleston

  • How does KAYAK find such low prices on flights from Florida Keys to Charleston?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to Charleston.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to Charleston?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Charleston from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to Charleston?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Charleston with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to Charleston?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Charleston from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Florida Keys to Charleston

 
Need help choosing which airline to fly with from Florida Keys to Charleston? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11669 reviews
7.2Comfort
6.9Entertainment
7.9Crew
7.5Boarding
6.4Food
Airline reviews

The seats need better cushioning for a nearly 5-hour flight, it was a bit uncomfortable. I'm glad American has free wi-fi but there were was a bout 30 minutes in the middle of the flight when there was no connection which was frustrating.

8.0 ExcellentJoseph, Apr 2026
TPA - PHX
Read more American Airlines reviews

The seats need better cushioning for a nearly 5-hour flight, it was a bit uncomfortable. I'm glad American has free wi-fi but there were was a bout 30 minutes in the middle of the flight when there was no connection which was frustrating.

My original flight got delayed day of so I had to rebook it from one layover to two layovers. The flight also left earlier which was a slight inconvenience but manageable. Then my first connection flight got delayed 3 separate times for a total of 2 hours delayed, causing me to miss my second connection flight back to Santa Barbara. Now, because of this missed flight, I am missing my college classes that I pay for.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

This short sector between Miami and JFK was undertaken purely for business purposes, with efficiency as the primary objective rather than a full inflight experience. Overall, the journey met its intended purpose; however, the ground experience at Miami stood out significantly. During check-in, I was unable to link my frequent flyer details from Qatar Airways (oneworld alliance) through either the self-service kiosk or web check-in. The situation was handled exceptionally well by the check-in agent, who demonstrated remarkable ownership. She coordinated across multiple counters, ensured my frequent flyer number was correctly reflected, reissued the boarding pass, and confirmed that mileage accrual would be recognized. Additionally, she ensured the boarding pass reflected priority status, enabling a seamless priority check-in experience without delays. This level of proactive service was both commendable and impactful. Boarding and the inflight experience, operated by American Airlines under a codeshare arrangement, were efficient but largely transactional. While operational delivery was smooth, there was no visible recognition of oneworld frequent flyer status onboard. In comparison to the consistently personalized engagement typically experienced with Qatar Airways, this absence was noticeable—though understandably a potential limitation of codeshare alignment rather than a direct service shortfall. In summary, while the flight itself fulfilled its operational intent, the exceptional professionalism and commitment demonstrated at the Miami check-in counter was the defining highlight of this journey. Greater consistency in elite recognition across partner airlines would further enhance the overall experience.

Business class was very good, one of my best flights

Incredibly delayed. First delay was due to plane coming in being late. Resulted in 30 minute delay. Boarded and then had multiple mechanical issues. Was on plane for an hour until they told people they could get off if they wanted but couldn't come back. Then gate agent rushed in and said they had lost control of who went off and we would all have to deplane and then get back on. They said flight had not been cancelled. Then while sitting waiting to board again they announced it would take two hours to get new plane and to wait at new gate. New plane arrived, reboarded only to find out that pilots had timed out. Waited for new pilots. In that time one of the flight attendants timed out. Never received food or water while waiting. Was confusing mess as to what was happening. Even flight attendants and gate agents were getting frustrated. Almost 6 hours delayed. Called American to received flight credit but can't get anywhere as Kayak reservation and don't have a ticket number. Reached out to Kayak but never heard back.

The new planes (American Eagle) are beautiful and especially comfortable. The flight attendants are consistently professional and courteous. And, while it may seem inconsequential, the new liquid tube of coffee creamer—in contrast to the powdered coffee creamer—makes all the difference in a cup of coffee.

Flight was delayed and they gave up my seat on my connection, even when I could still make the flight

Bag drop was very disorganized in Miami. All main cabin passengers were shunted to just a few lanes and they had an equal number of lanes for first class passengers but there was nobody on those lines. They did nothing to bring the main cab and passengers over to the open lines and they just had employees standing there and doing nothing

Crew at the gate was very crabby and not at all polite. The plane was very hot the entire flight. And the seat cushion was very worn out.

There was a crack in my window seal. And Spirit is now closed forever.

They closed the doors earlier than posted. I missed my flight with a slim 5 minutes bc they closed the doors earlier than earlier. My luggage never made it onto the flight and I had to find a new flight to Dallas bc the only option they could rebook me on was for leaving miami.

The AC broke and we were onboard for 2 hrs waiting for them to fix it. It was so hot and we could not get any water or anything to drink. They finally let us off the plane after the second attempt and we boarded a new plane. We didn't land till 12:15am!

There was no flight. Call the airline and confirmed. I have no idea why you think that I flew on the days that you say I did.

Easy to get our TSA pre check #added. Flight crew was great and entertaining and we landed early!

baggage drop off was a bit much. I felt like I worked for spirit airlines since I did all the work.

Gate changed multiple times. The staff seemed annoyed that we asked for water. We had to pay for the water as well.

We didn't get on the flight, they canceled our flight and said there was no flights leaving this weekend and sent me our money back.

Horrible company: canceled flights and delayed flights. Spirit canceled my flight from Miami to Philadelphia the day before we were supposed to leave from Philadelphia to Miami, with no explanation. I had to rebook another flight, spending more money and instead of flying from Miami, I had to choose a flight from Fort Lauderdale because there were no direct flights available from Miami. That created additional cost. The flight with Spirit from Fort Lauderdale was scheduled to depart at 6am, so I had to wake up my 3 and 6 years old at 3am to get to the airport in time and then, at 5am while we were at the gate the delayed the flight until 7:45am with again no explanation.

Unfortunately Stuff and the stuff boarded us were so rude to many of passengers.i will never fly Spirit again .

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Walterboro
Goose Creek

Everything you need to know for your flight to Charleston

Information on the airport you'll fly into in Charleston