RSW - DSM

$76 Find Cheap Flights from Fort Myers to Des Moines - Compare and Save

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Everything you should know

Cheapest round-trip
$76
Typical prices: $202-$495
Allegiant Air
Tue 12/4Fri 12/7
RSW - DSM • Non-stop
Cheapest one-way
$119
Typical prices: $156-$362
Allegiant Air
Fri 11/9
RSW - DSM • Non-stop
Nonstop flights
2 days a week
You can fly direct with Allegiant Air. Average duration is 3h 21m
Direct flights
+1
Direct flights
+1
When to travel
December
Cheapest • 64% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Chicago O'Hare Intl (ORD)
Cheapest • Avg $359 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 5h 19m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Fort Myers to Des Moines (RSW-DSM)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Fort Myers to Des Moines

Fri, Dec 4 - Mon, Dec 7
Allegiant Air Logo
7:53 pm - 10:21 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
3h 28mnonstop
Allegiant Air Logo
3:05 pm - 7:03 pmDSM  Des Moines-RSW Fort Myers SW Florida Intl
2h 58mnonstop
$76Allegiant Air
Fri, Dec 4 - Mon, Dec 7
Allegiant Air Logo
7:53 pm - 10:21 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
3h 28mnonstop
Allegiant Air Logo
3:05 pm - 7:03 pmDSM  Des Moines-RSW Fort Myers SW Florida Intl
2h 58mnonstop
$81Allegiant Air
Fri, Dec 4 - Mon, Dec 7
Allegiant Air Logo
7:53 pm - 10:21 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
3h 28mnonstop
Allegiant Air Logo
3:05 pm - 7:03 pmDSM  Des Moines-RSW Fort Myers SW Florida Intl
2h 58mnonstop
$83Allegiant Air
Fri, Dec 4 - Mon, Dec 7
Multiple Airlines Logo
7:53 pm - 10:21 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
3h 28mnonstop
Multiple Airlines Logo
10:40 am - 6:48 pmDSM  Des Moines-RSW Fort Myers SW Florida Intl
31h 08m3 stops Nashville Intl Orlando Raleigh-Durham
$237Multiple Airlines
Fri, Dec 4 - Mon, Dec 7
Multiple Airlines Logo
7:53 pm - 10:21 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
3h 28mnonstop
Multiple Airlines Logo
10:40 am - 6:48 pmDSM  Des Moines-RSW Fort Myers SW Florida Intl
31h 08m3 stops Nashville Intl Orlando Raleigh-Durham
$253Multiple Airlines
Mon, Dec 7 - Mon, Dec 14
Multiple Airlines Logo
7:53 pm - 10:21 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
3h 28mnonstop
Multiple Airlines Logo
9:18 pm - 7:47 pmDSM  Des Moines-RSW Fort Myers SW Florida Intl
21h 29m3 stops Las Vegas Harry Reid Intl Dallas/Fort Worth Detroit Metropolitan Wayne County
$261Multiple Airlines
Sat, Dec 12 - Mon, Dec 14
American Airlines Logo
8:37 am - 1:35 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
5h 58m1 stop Chicago O'Hare Intl
American Airlines Logo
9:23 am - 6:33 pmDSM  Des Moines-RSW Fort Myers SW Florida Intl
8h 10m1 stop Chicago O'Hare Intl
$295American Airlines
Wed, Jan 13 - Tue, Jan 19
Delta Logo
10:12 am - 5:19 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
8h 07m1 stop Detroit Metropolitan Wayne County
Delta Logo
5:22 pm - 12:35 amDSM  Des Moines-RSW Fort Myers SW Florida Intl
6h 13m1 stop Atlanta Hartsfield-Jackson
$339Delta
Wed, Jan 13 - Tue, Jan 19
Delta Logo
10:12 am - 5:19 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
8h 07m1 stop Detroit Metropolitan Wayne County
Delta Logo
5:22 pm - 12:35 amDSM  Des Moines-RSW Fort Myers SW Florida Intl
6h 13m1 stop Atlanta Hartsfield-Jackson
$355Delta
Wed, Jan 13 - Tue, Jan 19
American Airlines Logo
11:11 am - 7:13 pmRSW  Fort Myers SW Florida Intl-DSM Des Moines
9h 02m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
10:26 am - 6:41 pmDSM  Des Moines-RSW Fort Myers SW Florida Intl
7h 15m1 stop Chicago O'Hare Intl
$366American Airlines
Booking Insights

Price, demand and travel trends for Fort Myers to Des Moines flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Fort Myers to Des Moines?

Round-trip flights from Fort Myers to Des Moines typically range from $202 to $495. The lowest price found in the past 5 days was $76, on Allegiant Air.

What’s the cheapest month to fly from Fort Myers to Des Moines?

•December is the cheapest month to fly from Fort Myers to Des Moines at $140 round-trip.
•April ($536) and July ($522) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 282% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Fort Myers to Des Moines flights

Low season

February

Cheapest flight

$76
Beat the crowds with an average 49% drop in travelers.
The most popular month to fly with an average 36% increase in travelers.
Round-trip flight from Fort Myers to Des Moines

When to book flights from Fort Myers to Des Moines

Are your dates flexible? Find out the best times to travel from Fort Myers to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Fort Myers to Des Moines flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What are the earliest and latest flights from Fort Myers to Des Moines?

    These are the earliest and latest flight times available from Fort Myers to Des Moines:

    • Earliest: departs at 10:45 am and lands at 2:06 pm
    • Latest: departs at 8:00 pm and lands at 11:21 pm.

    The flight takes about 3h 21m.

  • What cabin classes can I book on flights from Fort Myers to Des Moines?

    Only Economy Class is available on flights from Fort Myers to Des Moines.

  • How long is a flight from Fort Myers to Des Moines?

    A nonstop flight from Fort Myers to Des Moines takes 3h 21m, covering 1,237 miles.

  • Do I need a passport to fly from Fort Myers to Des Moines?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Fort Myers to Des Moines flight?

    Round-trip flights from Fort Myers to Des Moines range from $202 to $495, with an average of $384 over the past 12 months. Anything below $202 counts as a good deal.

  • How much can I save by taking a layover when flying from Fort Myers to Des Moines?

    On this route, nonstop flights are cheaper than layover options on average. Nonstop fares average $122 round-trip, compared to $359 via a layover through Chicago O'Hare Intl (ORD).

  • What is the standard checked-bag allowance on flights from Fort Myers to Des Moines?

    There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $45–$90 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from Fort Myers to Des Moines?

    The Airbus A320-100/200 family is used most often on this route, operated mainly by Allegiant Air. Other aircraft seen on the route include Airbus A319 variants.

  • How are flight prices from Fort Myers to Des Moines looking right now?

    One-way fares from Fort Myers to Des Moines are currently higher than usual. Average one-way flight prices are about $287, which is 37% above the typical average for this route.

  • What car rental options are available at Des Moines Airport (DSM)?

    Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates averaging $81 for economy cars. Top options include:

    • Hertz
    • Payless
    • Budget
    • Alamo
    • Avis

  • Which airports can I use when flying from Fort Myers to Des Moines?

    Flights from Fort Myers to Des Moines usually depart from Fort Myers SW Florida Intl (RSW) and arrive at Des Moines (DSM).

  • Which airports do connecting flights from Fort Myers to Des Moines pass through?

    One-stop flights from Fort Myers to Des Moines most commonly connect through:

    • Charlotte Douglas (CLT) - 35% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 30% of one-stop connections
    • Minneapolis St Paul (MSP) - 15% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 15% of one-stop connections

  • Can I save money by using flexible dates for flights from Fort Myers to Des Moines?

    Yes. Flexible dates can save you up to 82% on flights from Fort Myers to Des Moines. Friday is the cheapest departure day at $122 round-trip on average, while Tuesday is the most expensive at $649, a difference of $527.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What airlines fly from Fort Myers to Des Moines?

    Only Allegiant Air operates flights between Fort Myers and Des Moines.

  • How much time can I save by choosing a different layover airport from Fort Myers to Des Moines?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 5h 19m, compared with 5h 22m via Chicago Midway (MDW) and 5h 39m via Charlotte Douglas (CLT).

  • What is the time difference between Fort Myers and Des Moines?

    Des Moines is 1 hour behind Fort Myers (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Des Moines?

    Some of the most popular sights in Des Moines are UnityPoint Health - Des Moines, Science Center of Iowa and Hy Vee Hall. These are among the most viewed places in Des Moines on KAYAK.

Your guide to booking Fort Myers to Des Moines flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Friday departure and avoid flying on Tuesday. On this route, Friday flights average $122, about $527 less than Tuesday fares (81% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Fort Myers to Des Moines trip for December. Fares historically average $140 round-trip in that month - typically $396 less than the most expensive month, which is April (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Des Moines Airport.

    • Days Inn & Suites by Wyndham Des Moines Airport
    • Quality Inn & Suites Des Moines Airport
    • Homewood Suites by Hilton - Des Moines Airport

Prefer to fly direct from Fort Myers to Des Moines?

 
Find which airlines fly direct from Fort Myers SW Florida Intl Airport to Des Moines Airport, which days they fly and book direct flights.

Direct departures

Fort Myers SW Florida Intl to Des Moines

Monday

Allegiant Air

Allegiant Air

Wednesday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Des Moines to Fort Myers SW Florida Intl

Monday

Allegiant Air

Allegiant Air

Wednesday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

More options for your flight from Fort Myers to Des Moines

Complete your trip to Des Moines with a hotel stay or car rental

Car rentals in Des Moines
Hotels in Des Moines
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