GSP - SCL

$966 Find Cheap Flights from Greenville to Santiago

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Santiago departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$966
LATAM Airlines
Thu 10/29Mon 11/2
GSP - SCL • 2 stops
Top airlines
LATAM Airlines
Cheapest • from $966 (round-trip)
LATAM Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Greenville and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Miami (MIA)
Cheapest • Avg $1,113 (round-trip)
Miami (MIA)
Shortest trip • 11h 19m (one-way)
Insights
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We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Greenville to Santiago (GSP-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Santiago

Thu, Oct 29 - Mon, Nov 2
LATAM Airlines Logo
5:05 pm - 5:30 pm
GSP
-
SCL
23h 25m
2 stops
LATAM Airlines Logo
11:05 pm - 11:37 pm
SCL
-
GSP
26h 32m
2 stops
$966LATAM Airlines
Mon, Jun 15 - Sun, Jun 21
Multiple Airlines Logo
8:28 pm - 3:00 am
GSP
-
SCL
30h 32m
2 stops
Multiple Airlines Logo
11:25 pm - 8:40 pm
SCL
-
GSP
21h 15m
1 stop
$1,062Multiple Airlines
Thu, Aug 20 - Sun, Aug 23
Copa Airlines Logo
7:00 am - 10:43 pm
GSP
-
SCL
15h 43m
2 stops
Copa Airlines Logo
12:06 am - 10:53 pm
SCL
-
GSP
22h 47m
2 stops
$1,075Copa Airlines
Mon, Jun 29 - Mon, Jul 6
American Airlines Logo
12:37 pm - 7:05 am
GSP
-
SCL
18h 28m
2 stops
American Airlines Logo
9:00 pm - 3:42 pm
SCL
-
GSP
18h 42m
2 stops
$1,180American Airlines
Mon, Jun 29 - Mon, Jul 6
American Airlines Logo
4:06 pm - 7:05 am
GSP
-
SCL
14h 59m
2 stops
American Airlines Logo
9:00 pm - 7:30 pm
SCL
-
GSP
22h 30m
1 stop
$1,190American Airlines
Mon, Jun 29 - Mon, Jul 6
American Airlines Logo
6:00 am - 7:05 am
GSP
-
SCL
25h 05m
1 stop
American Airlines Logo
9:00 pm - 7:30 pm
SCL
-
GSP
22h 30m
1 stop
$1,196American Airlines
Thu, Aug 13 - Mon, Aug 17
Copa Airlines Logo
5:50 am - 5:14 am
GSP
-
SCL
23h 24m
2 stops
Copa Airlines Logo
11:22 am - 9:48 am
SCL
-
GSP
22h 26m
2 stops
$1,207Copa Airlines
Tue, Jun 2 - Tue, Jun 9
Copa Airlines Logo
7:40 pm - 11:26 pm
GSP
-
SCL
27h 46m
2 stops
Copa Airlines Logo
11:17 am - 9:55 am
SCL
-
GSP
22h 38m
2 stops
$1,238Copa Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
5:15 pm - 7:50 am
GSP
-
SCL
13h 35m
1 stop
United Airlines Logo
10:45 pm - 3:18 pm
SCL
-
GSP
18h 33m
1 stop
$1,245United Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
5:15 pm - 7:50 am
GSP
-
SCL
13h 35m
1 stop
United Airlines Logo
10:45 pm - 9:11 pm
SCL
-
GSP
24h 26m
2 stops
$1,250United Airlines
Booking Insights

KAYAK's insights & trends for Greenville to Santiago flights

Get data-powered insights and trends into flights from Greenville to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Greenville to Santiago?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 7 days.

In the past 7 days, the cheapest round-trip tickets from Greenville to Santiago were found on LATAM Airlines ($966) and Copa Airlines ($1,075).

Find deals

Good to know

Cheapest flight$966
Flight from Greenville to Santiago

When to book flights from Greenville to Santiago

Are your dates flexible? Find out the best times to travel from Greenville to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Greenville to Santiago

  • What is the cheapest flight from Greenville to Santiago?

    In the last 7 days, the lowest price for a flight from Greenville to Santiago was $966 for a round-trip ticket.

  • Do I need a passport to fly between Greenville and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Greenville and on arrival in Santiago.

  • Which airports will I be using when flying from Greenville to Santiago?

    Greenville airport is called Greenville and the only airport in Santiago is Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Greenville to Santiago?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Greenville to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Greenville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Greenville with another airline. Booking your flights between Greenville and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Greenville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Greenville to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Greenville to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Greenville to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1918 reviews
7.5Boarding
8.0Crew
7.0Entertainment
6.7Food
7.3Comfort
Airline reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

10.0 ExcellentYelen, Mar 2026
ATL - TPA
Read more LATAM Airlines reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Everything you need to know for your flight from Greenville to Santiago

Information on your arrival and departure airports

Greenville (GSP)
Santiago (SCL)