GSP - SCL

$627 Find Cheap Flights from Greenville to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Santiago departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$829
Multiple Airlines
Fri 5/1Fri 5/15
GSP - SCL • 2 stops
Cheapest one-way
$627
American Airlines
Sat 5/2
GSP - SCL • 2 stops
Top airlines
Cheapest • from $1,163 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Greenville and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $1,113 (round-trip)
Shortest trip • 11h 19m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Greenville to Santiago (GSP-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Santiago

Fri, May 1 - Fri, May 15
Multiple Airlines Logo
8:18 pm - 10:43 pm
GSP
-
SCL
50h 25m
2 stops
Multiple Airlines Logo
11:17 am - 1:18 pm
SCL
-
GSP
50h 01m
2 stops
$829Multiple Airlines
Thu, Aug 20 - Tue, Aug 25
LATAM Airlines Logo
5:05 pm - 6:55 am
GSP
-
SCL
13h 50m
2 stops
LATAM Airlines Logo
12:40 am - 6:52 pm
SCL
-
GSP
18h 12m
2 stops
$1,163LATAM Airlines
Sat, May 30 - Sat, Jun 6
LATAM Airlines Logo
5:05 pm - 6:55 am
GSP
-
SCL
13h 50m
2 stops
LATAM Airlines Logo
7:45 am - 11:43 pm
SCL
-
GSP
15h 58m
2 stops
$1,170LATAM Airlines
Sat, May 30 - Sat, Jun 6
American Airlines Logo
12:12 pm - 7:05 am
GSP
-
SCL
18h 53m
1 stop
American Airlines Logo
9:00 pm - 6:59 pm
SCL
-
GSP
21h 59m
2 stops
$1,180American Airlines
Sat, May 30 - Sat, Jun 6
American Airlines Logo
12:12 pm - 7:05 am
GSP
-
SCL
18h 53m
1 stop
American Airlines Logo
9:00 pm - 7:45 pm
SCL
-
GSP
22h 45m
1 stop
$1,186American Airlines
Thu, Aug 20 - Wed, Aug 26
American Airlines Logo
6:44 pm - 6:50 am
GSP
-
SCL
12h 06m
1 stop
American Airlines Logo
8:30 pm - 6:14 pm
SCL
-
GSP
21h 44m
1 stop
$1,195American Airlines
Thu, Aug 20 - Wed, Aug 26
American Airlines Logo
2:35 pm - 6:50 am
GSP
-
SCL
16h 15m
2 stops
American Airlines Logo
8:30 pm - 6:14 pm
SCL
-
GSP
21h 44m
1 stop
$1,200American Airlines
Sat, May 30 - Sat, Jun 6
LATAM Airlines Logo
6:45 am - 10:49 am
GSP
-
SCL
28h 04m
3 stops
LATAM Airlines Logo
7:45 am - 9:18 am
SCL
-
GSP
25h 33m
2 stops
$1,207LATAM Airlines
Sat, May 16 - Sat, May 23
American Airlines Logo
12:49 pm - 7:05 am
GSP
-
SCL
18h 16m
2 stops
American Airlines Logo
9:00 pm - 12:10 pm
SCL
-
GSP
15h 10m
2 stops
$1,230American Airlines
Thu, Aug 20 - Wed, Aug 26
LATAM Airlines Logo
5:05 pm - 1:25 pm
GSP
-
SCL
20h 20m
3 stops
LATAM Airlines Logo
4:10 am - 11:38 pm
SCL
-
GSP
19h 28m
2 stops
$1,232LATAM Airlines
Booking Insights

KAYAK's insights & trends for Greenville to Santiago flights

Get data-powered insights and trends into flights from Greenville to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Greenville to Santiago?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Greenville to Santiago were found on LATAM Airlines ($1,163) and American Airlines ($1,180).

Good to know

Cheapest flight$627
Flight from Greenville to Santiago

When to book flights from Greenville to Santiago

Are your dates flexible? Find out the best times to travel from Greenville to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Greenville to Santiago

  • What is the cheapest flight from Greenville to Santiago?

    In the last 3 days, the lowest price for a flight from Greenville to Santiago was $627 for a one-way ticket and $829 for a round-trip.

  • Do I need a passport to fly between Greenville and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Greenville and on arrival in Santiago.

  • Which airports will I be using when flying from Greenville to Santiago?

    Greenville airport is called Greenville and the only airport in Santiago is Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Greenville to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Greenville to Santiago?

    SkyTeam is the only airline alliance operating flights between Greenville and Santiago.

  • Which is the best airline for flights from Greenville to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Greenville to Santiago are Delta and LATAM Airlines. With an average price for the route of $948 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $1,185 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Greenville to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Greenville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Greenville with another airline. Booking your flights between Greenville and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Greenville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Greenville to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Greenville to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Greenville to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8365 reviews
8.1Boarding
7.2Food
7.8Entertainment
7.9Comfort
8.5Crew
Airline reviews

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

10.0 ExcellentViraj, Apr 2026
JFK - SFO
Read more Delta reviews

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

On the return flight, flight attendant Britt went out of her way to inform passengers that several of us had tight connections.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Staff at the check-in counter were friendly, happy and helpful. They tagged our bags and sent us to “bag drop off” but were not very clear about where that was. The airport was busy we headed off in what we thought was the right direction until a gentleman waved us down and actually came after us. He was the baggage handler for Delta and recognized our “deer in the headlights “ look-he brought us to the right area (which was marked as the Southwest Airlines Drop Off) and sent us on our way. Wonderful guy, low key and working with a big smile on his face. Loved it. Loved him.

During the flight, the only refreshments provided were crackers and soft drinks; no substantial food was offered despite the international route. Furthermore, our initial flight was delayed, causing us to miss the connecting flight in Atlanta. The airline did not hold the connection, and we were informed that the next available flight is not for another 24 hours. While I am aware of alternative options via JetBlue, they operate out of JFK, which is not a viable solution for us as a resident of New Jersey.

Arlene was a great flight attendant. I also liked how one of the other flight attendants gave us a heads up about snacks and asked everyone to remove their headphones when it was their turn to order. Good idea.

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I haven’t flown economy in over 20 years but it was not bad. Room by my feet for my bag and seat was roomy enough. Surprised in a good way.

The flight was delayed 90 minutes The Gate was wrong The Restroom on Aircraft was not clean There was a half used water bottle in my seat

Delta is always a wonderful experience. A clean plane and the crew is really friendly.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Everything you need to know for your flight from Greenville to Santiago

Information on your arrival and departure airports