GSP - SCL

$518 Find Cheap Flights from Greenville to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Santiago departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Santiago, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Greenville to Santiago (GSP-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Santiago

Wed, Oct 15 - Mon, Oct 27
LATAM Airlines Logo
5:36 pm - 1:55 pmGSP-SCL
19h 19m2 stops
LATAM Airlines Logo
11:25 pm - 6:56 pmSCL-GSP
20h 31m2 stops
$723LATAM Airlines
Find Deal
Wed, Oct 15 - Mon, Oct 27
Delta Logo
5:36 pm - 2:25 pmGSP-SCL
19h 49m2 stops
Delta Logo
10:10 pm - 6:56 pmSCL-GSP
21h 46m1 stop
$734Delta
Find Deal
Wed, Oct 1 - Tue, Oct 14
LATAM Airlines Logo
6:13 pm - 7:00 amGSP-SCL
11h 47m1 stop
LATAM Airlines Logo
9:40 pm - 10:09 amSCL-GSP
13h 29m1 stop
$744LATAM Airlines
Find Deal
Thu, Nov 6 - Wed, Nov 19
LATAM Airlines Logo
11:04 am - 11:05 amGSP-SCL
46h 01m3 stops
LATAM Airlines Logo
12:25 pm - 9:02 amSCL-GSP
22h 37m2 stops
$764LATAM Airlines
Find Deal
Wed, Oct 15 - Sun, Oct 26
LATAM Airlines Logo
1:45 pm - 7:00 amGSP-SCL
16h 15m1 stop
LATAM Airlines Logo
12:25 am - 6:56 pmSCL-GSP
19h 31m2 stops
$784LATAM Airlines
Find Deal
Sun, Oct 19 - Sun, Oct 26
LATAM Airlines Logo
7:41 pm - 2:30 pmGSP-SCL
41h 49m2 stops
LATAM Airlines Logo
8:50 pm - 11:55 pmSCL-GSP
28h 05m2 stops
$786LATAM Airlines
Find Deal
Sun, Oct 19 - Sun, Oct 26
LATAM Airlines Logo
5:16 pm - 7:00 amGSP-SCL
12h 44m1 stop
LATAM Airlines Logo
4:40 pm - 11:55 pmSCL-GSP
32h 15m2 stops
$809LATAM Airlines
Find Deal
Tue, Sep 23 - Fri, Oct 3
Delta Logo
2:33 pm - 7:50 amGSP-SCL
16h 17m2 stops
Delta Logo
10:55 pm - 4:16 pmSCL-GSP
18h 21m2 stops
$878Delta
Find Deal
Tue, Sep 23 - Fri, Oct 3
Delta Logo
2:33 pm - 7:00 amGSP-SCL
15h 27m1 stop
Delta Logo
9:40 pm - 1:09 pmSCL-GSP
16h 29m1 stop
$2,044Delta
Find Deal
Tue, Sep 23 - Thu, Oct 2
Copa Airlines Logo
10:15 am - 5:58 amGSP-SCL
18h 43m2 stops
Copa Airlines Logo
1:24 am - 7:06 pmSCL-GSP
18h 42m2 stops
$6,082Copa Airlines
Find Deal

Everything you should know

Top airlines
LATAM Airlines
Cheapest • from $723 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$723
LATAM Airlines
Wed 10/15Mon 10/27
GSP - SCL • 2 stops
Cheapest one-way
$518
Delta
Thu 1/1
GSP - SCL • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Booking Insights

KAYAK's insights & trends for Greenville to Santiago flights

Get data-powered insights and trends into flights from Greenville to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Greenville to Santiago?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Greenville to Santiago were found on LATAM Airlines ($723) and Delta ($734).

Good to know

Low seasonNovember
Cheapest flight$518
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from Greenville to Santiago

When to book flights from Greenville to Santiago

Are your dates flexible? Find out the best times to travel from Greenville to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Greenville to Santiago

  • What is the cheapest flight from Greenville to Santiago?

    In the last 3 days, the lowest price for a flight from Greenville to Santiago was $518 for a one-way ticket and $723 for a round-trip.

  • Do I need a passport to fly between Greenville and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Greenville and on arrival in Santiago.

  • Which airports will I be using when flying from Greenville to Santiago?

    Greenville airport is called Greenville and the only airport in Santiago is Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Greenville to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Greenville to Santiago?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Greenville and Santiago, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Greenville to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Greenville to Santiago are Delta and LATAM Airlines. With an average price for the route of $988 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $894 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Greenville to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Greenville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Greenville with another airline. Booking your flights between Greenville and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Greenville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Greenville to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Greenville to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Greenville to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7977 reviews
7.9Comfort
7.3Food
7.9Entertainment
8.5Crew
8.2Boarding
Airline reviews

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

2.0 MediocreAnonymous, Sep 2025SNA - SEA
Read more Delta reviews

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Quick check in. Everything went smooth. I don't know what can be done about airline food.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Nothing special. The crew never went out of their way for anything.

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

The flight attendants in SLC were rude. I arrived 40 minutes early to gate. Ticket said I needed check in for seat assignments and tried check in and attendants said they weren’t doing it. And proceeded to never call me to give me a ticket so when time to board I received the very last seat. Please relay to employees to do their job better..,

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

The boarding and new bag drop-off process was confusing and causing massive delays.

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

Everything you need to know for your flight from Greenville to Santiago

Information on your arrival and departure airports

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