GSP - SCL

$1,121 Find Cheap Flights from Greenville to Santiago - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$1,121
Typical prices: $965-$1,362
United Airlines
Mon 11/19Mon 11/26
GSP - SCL • 1 stop
Cheapest one-way
$1,746
Typical prices: $558-$668
LATAM Airlines
Thu 10/25
GSP - SCL • 3 stops
Nonstop flights
There are currently no direct flights between Greenville and Santiago. You'll need to take a connecting flight to reach the destination.
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Cheap Flights from Greenville to Santiago (GSP-SCL)

 

Cheap flights from Greenville to Santiago with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Thu, Nov 19 - Thu, Nov 26
United Airlines Logo
5:12 pm - 8:50 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
13h 38m1 stop Houston George Bush Intcntl
United Airlines Logo
10:45 pm - 4:28 pmSCL  Santiago Arturo Merino Benitez-GSP Greenville
19h 43m1 stop Houston George Bush Intcntl
$1,121United Airlines
Wed, Feb 24 - Sun, Mar 7
Copa Airlines Logo
7:00 am - 12:24 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
15h 24m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
Copa Airlines Logo
12:30 pm - 9:46 amSCL  Santiago Arturo Merino Benitez-GSP Greenville
23h 16m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$1,124Copa Airlines
Thu, Nov 19 - Thu, Nov 26
United Airlines Logo
5:12 pm - 8:50 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
13h 38m1 stop Houston George Bush Intcntl
United Airlines Logo
10:45 pm - 11:47 pmSCL  Santiago Arturo Merino Benitez-GSP Greenville
27h 02m2 stops Houston George Bush Intcntl Newark
$1,125United Airlines
Wed, Nov 4 - Wed, Nov 11
Copa Airlines Logo
6:49 am - 5:46 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
20h 57m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
Copa Airlines Logo
12:15 pm - 9:30 amSCL  Santiago Arturo Merino Benitez-GSP Greenville
23h 15m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$1,134Copa Airlines
Thu, Oct 22 - Wed, Nov 11
Delta Logo
10:08 am - 7:00 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
19h 52m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
Delta Logo
8:25 pm - 9:35 amSCL  Santiago Arturo Merino Benitez-GSP Greenville
15h 10m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,136Delta
Wed, Feb 24 - Sun, Mar 7
United Airlines Logo
7:00 am - 8:50 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
23h 50m1 stop Houston George Bush Intcntl
United Airlines Logo
10:45 pm - 3:18 pmSCL  Santiago Arturo Merino Benitez-GSP Greenville
18h 33m1 stop Houston George Bush Intcntl
$1,151United Airlines
Wed, Feb 24 - Sun, Mar 7
United Airlines Logo
7:00 am - 8:50 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
23h 50m1 stop Houston George Bush Intcntl
United Airlines Logo
10:45 pm - 9:11 pmSCL  Santiago Arturo Merino Benitez-GSP Greenville
24h 26m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$1,155United Airlines
Wed, Nov 4 - Wed, Nov 11
United Airlines Logo
5:12 pm - 8:50 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
13h 38m1 stop Houston George Bush Intcntl
United Airlines Logo
10:45 pm - 4:28 pmSCL  Santiago Arturo Merino Benitez-GSP Greenville
19h 43m1 stop Houston George Bush Intcntl
$1,156United Airlines
Thu, Oct 22 - Tue, Oct 27
American Airlines Logo
8:08 pm - 8:10 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
11h 02m1 stop Miami
American Airlines Logo
10:15 pm - 5:37 pmSCL  Santiago Arturo Merino Benitez-GSP Greenville
20h 22m2 stops Miami Charlotte Douglas
$1,160American Airlines
Wed, Nov 4 - Wed, Nov 11
LATAM Airlines Logo
6:00 am - 7:30 amGSP  Greenville-SCL Santiago Arturo Merino Benitez
23h 30m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
LATAM Airlines Logo
11:10 pm - 9:35 amSCL  Santiago Arturo Merino Benitez-GSP Greenville
12h 25m1 stop Atlanta Hartsfield-Jackson
$1,162LATAM Airlines

Price, demand and travel trends for Greenville to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Greenville to Santiago?

Round-trip flights from Greenville to Santiago typically range from $965 to $1,362. The lowest price found in the past 5 days was $1,121, on United Airlines.

Key details for Greenville to Santiago flights

Cheapest flight

$1,121
Round-trip flight from Greenville to Santiago

When to book flights from Greenville to Santiago

Are your dates flexible? Find out the best times to travel from Greenville to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Greenville to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Greenville to Santiago?

    Two cabin classes are available on flights from Greenville to Santiago:

    • Economy Class
    • Business Class

  • How long is a flight from Greenville to Santiago?

    A nonstop flight from Greenville to Santiago takes 00m, covering 4,773 miles.

  • Do I need a passport to fly from Greenville to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Greenville to Santiago changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $1,121 to $2,911. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Greenville to Santiago looking right now?

    One-way fares from Greenville to Santiago are currently higher than usual. Average one-way flight prices are about $3,596, which is 501% above the typical average for this route.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around $6 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Greenville to Santiago?

    Flights from Greenville to Santiago usually depart from Greenville (GSP) and arrive at Santiago Arturo Merino Benitez (SCL).

  • Which airports do connecting flights from Greenville to Santiago pass through?

    Most connecting flights from Greenville to Santiago pass through Atlanta Hartsfield-Jackson (ATL), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from Greenville to Santiago?

    Yes. Flexible dates can save you up to 27% on flights from Greenville to Santiago. Thursday is the cheapest departure day at $1,119 round-trip on average, while Wednesday is the most expensive at $1,525, a difference of $406.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between Greenville and Santiago?

    Santiago is 1 hour ahead of Greenville (Chile Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Estadio Nacional Julio Martinez Pradanos, Espacio Riesco Convention and Exhibition Center and Costanera Center. These are among the most viewed places in Santiago on KAYAK.

Your guide to booking Greenville to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Wednesday. On this route, Thursday flights average $1,119, about $406 less than Wednesday fares (27% savings) based on the last 12 months.
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

More options for your flight from Greenville to Santiago

Complete your trip to Santiago with a hotel stay or car rental