GSP - SCL

$324 Find Cheap Flights from Greenville to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Santiago departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$804
American Airlines
Wed 4/1Wed 4/15
GSP - SCL • 1 stop
Cheapest one-way
$324
Multiple Airlines
Mon 1/12
GSP - SCL • 2 stops
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We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Greenville to Santiago (GSP-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Santiago

Wed, Apr 1 - Wed, Apr 15
American Airlines Logo
7:12 pm - 8:05 am
GSP
-
SCL
11h 53m1 stop
American Airlines Logo
8:50 pm - 6:11 pm
SCL
-
GSP
21h 21m1 stop
$804American Airlines
Wed, Apr 1 - Wed, Apr 15
American Airlines Logo
10:58 am - 8:05 am
GSP
-
SCL
20h 07m2 stops
American Airlines Logo
8:50 pm - 6:11 pm
SCL
-
GSP
21h 21m1 stop
$809American Airlines
Wed, Apr 1 - Wed, Apr 15
American Airlines Logo
3:58 pm - 8:05 am
GSP
-
SCL
15h 07m2 stops
American Airlines Logo
8:50 pm - 6:59 pm
SCL
-
GSP
22h 09m2 stops
$859American Airlines
Mon, Mar 23 - Wed, Mar 25
United Airlines Logo
4:55 pm - 7:50 am
GSP
-
SCL
13h 55m1 stop
United Airlines Logo
9:45 pm - 3:45 pm
SCL
-
GSP
19h 00m1 stop
$1,074United Airlines
Mon, Mar 23 - Wed, Mar 25
United Airlines Logo
6:30 am - 7:50 am
GSP
-
SCL
24h 20m2 stops
United Airlines Logo
9:45 pm - 2:17 pm
SCL
-
GSP
17h 32m2 stops
$1,079United Airlines
Mon, Mar 23 - Wed, Mar 25
LATAM Airlines Logo
5:23 pm - 2:10 pm
GSP
-
SCL
19h 47m3 stops
LATAM Airlines Logo
6:00 am - 9:52 pm
SCL
-
GSP
16h 52m2 stops
$1,366LATAM Airlines
Booking Insights

KAYAK's insights & trends for Greenville to Santiago flights

Get data-powered insights and trends into flights from Greenville to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Greenville and Santiago?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Greenville to Santiago.

There are 2 airlines that fly nonstop from Greenville to Santiago. They are Delta and LATAM Airlines. The cheapest airline for this route is LATAM Airlines, with the best round-trip deal found costing $793. On average, the best prices for this route can be found at LATAM Airlines.

Good to know

Cheapest flight$324
Flight from Greenville to Santiago

When to book flights from Greenville to Santiago

Are your dates flexible? Find out the best times to travel from Greenville to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Greenville to Santiago

  • What is the cheapest flight from Greenville to Santiago?

    In the last 3 days, the lowest price for a flight from Greenville to Santiago was $324 for a one-way ticket and $804 for a round-trip.

  • Do I need a passport to fly between Greenville and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Greenville and on arrival in Santiago.

  • Which airports will I be using when flying from Greenville to Santiago?

    Greenville airport is called Greenville and the only airport in Santiago is Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Greenville to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Greenville to Santiago?

    SkyTeam is the only airline alliance operating flights between Greenville and Santiago.

  • Which is the best airline for flights from Greenville to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Greenville to Santiago are Delta and LATAM Airlines. With an average price for the route of $948 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $944 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Greenville to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Greenville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Greenville with another airline. Booking your flights between Greenville and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Greenville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Greenville to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Greenville to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Greenville to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8008 reviews
8.1Boarding
7.3Food
7.9Entertainment
7.9Comfort
8.5Crew
Airline reviews

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

10.0 ExcellentVenkata Krishna, Dec 2025
ATL - SDF
Read more Delta reviews

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Everything you need to know for your flight from Greenville to Santiago

Information on your arrival and departure airports