$222 Find Cheap Flights from Indianapolis to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Indianapolis to Panama departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Indianapolis to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Indianapolis to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Indianapolis to Panama

Thu, Feb 26 - Sun, Mar 1
Multiple Airlines Logo
9:28 am - 1:00 am
IND
-
PTY
15h 32m2 stops
Multiple Airlines Logo
2:55 am - 10:48 pm
PTY
-
IND
19h 53m2 stops
$450Multiple Airlines
Thu, Feb 26 - Sun, Mar 1
Multiple Airlines Logo
9:28 am - 1:00 am
IND
-
PTY
15h 32m2 stops
Multiple Airlines Logo
2:55 am - 10:48 pm
PTY
-
IND
19h 53m2 stops
$472Multiple Airlines
Mon, Feb 2 - Fri, Feb 6
Multiple Airlines Logo
10:38 am - 12:40 am
IND
-
PTY
14h 02m2 stops
Multiple Airlines Logo
2:55 am - 10:48 pm
PTY
-
IND
19h 53m2 stops
$475Multiple Airlines
Sat, Jan 24 - Wed, Jan 28
Multiple Airlines Logo
7:43 pm - 10:30 am
IND
-
PTY
14h 47m2 stops
Multiple Airlines Logo
7:50 pm - 10:28 am
PTY
-
IND
14h 38m2 stops
$487Multiple Airlines
Tue, Mar 24 - Wed, Apr 1
United Airlines Logo
9:00 am - 4:07 pm
IND
-
PTY
8h 07m1 stop
United Airlines Logo
9:45 am - 8:33 pm
PTY
-
IND
9h 48m1 stop
$491United Airlines
Sat, Jan 24 - Wed, Jan 28
Avianca Logo
7:43 pm - 2:55 pm
IND
-
PTY
19h 12m3 stops
Avianca Logo
3:50 pm - 10:28 am
PTY
-
IND
18h 38m2 stops
$494Avianca
Tue, Mar 24 - Wed, Apr 1
United Airlines Logo
6:00 am - 6:38 pm
IND
-
PTY
13h 38m2 stops
United Airlines Logo
9:45 am - 8:33 pm
PTY
-
IND
9h 48m1 stop
$495United Airlines
Mon, Feb 2 - Sun, Feb 8
Multiple Airlines Logo
10:38 am - 12:40 am
IND
-
PTY
14h 02m2 stops
Multiple Airlines Logo
2:55 am - 10:48 pm
PTY
-
IND
19h 53m2 stops
$496Multiple Airlines
Mon, Mar 30 - Fri, Apr 3
American Airlines Logo
5:38 pm - 12:40 pm
IND
-
PTY
20h 02m2 stops
American Airlines Logo
1:40 pm - 10:42 am
PTY
-
IND
20h 02m2 stops
$500American Airlines
Sat, Mar 21 - Wed, Apr 8
Copa Airlines Logo
6:00 am - 4:10 am
IND
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PTY
23h 10m1 stop
Copa Airlines Logo
7:55 am - 9:32 pm
PTY
-
IND
12h 37m1 stop
$501Copa Airlines
Booking Insights

KAYAK's insights & trends for Indianapolis to Panama flights

Get data-powered insights and trends into flights from Indianapolis to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Indianapolis to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Indianapolis to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Indianapolis to Panama is September, when tickets cost $489 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $1,364 and $673 respectively.

How far in advance should I book a flight from Indianapolis to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Indianapolis to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Indianapolis to Panama, you should book around 6 weeks before departure, which saves you about 4% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 20 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$222
Best time to beat the crowds with an average 12% drop in price.
Flight from Indianapolis to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Indianapolis to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Indianapolis to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Indianapolis to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Indianapolis to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Indianapolis to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Indianapolis to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Indianapolis to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Indianapolis to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Indianapolis to Panama

 
Need help choosing which airline to fly with from Indianapolis to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8022 reviews
7.9Comfort
8.5Crew
7.2Food
8.1Boarding
7.8Entertainment
Airline reviews

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

8.0 ExcellentG, Jan 2026
ATL - FLL
Read more Delta reviews

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Flight was late from Newark to Atlanta, I asked flight attendant to please let my family of 3 out first when we landed to Atlanta because we were late for our connecting flight to Quito. She didn't and we were late for 5 minutes we couldn't board the plane and spend hours trying to get another flight with customer service for the next day.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Late delayed flight delays boarding and delays leaving and delays on arrival too. Cramped plane no room no food.

DTW line is too long. The flights from DTW to BWI are always delayed for unknown reasons.

Delta canceled our flight and we had to scramble to find another airline to get home. Phoenix is not a delta hub so they didn’t have another plane. It would have been a red eye though Salt Lake City. Getting in at 5am. No bueno.

This flight was no comparison to our prior flight. I'm thinking it all has to do with the age of the aircraft.

This flight was a first class choice and left much to be desired. Seat backs on seats were falling apart and torn. Seats actually didn't come to a "full & upright position". Pull out table was sprung. Not any significant leg room. All in all we were on an obviously older plane and felt overcharged for what we received as first class.

A 12 hour flight during the day with one real meal service - are you kidding? Also the breakfast was one of the worst and not what was listed

Flight was delayed several times. At one point, they "pulled back" 15 minutes from the delayed boarding and sent a text saying we would board sooner than previously advised. The flight then was delayed again. And when we boarded, there was an unspecified technical issue which had us waiting in the plane for about an hour.

It was great with United overall except for two things. 1) It was a 5-hour flight and we were with kids, so we were asking for extra snacks. They were extremely reticent to dole them out even though there wasn't any meal and the kids were starting to hit their limit towards the end. 2) Baggage didn't arrive until 80 minutes after we landed.

They lost my luggage, so, not happy. The crew was nice but my suitcases never made it, still trying to find out what happened!

The staff was hospitable and professional. The seat had a bit of wear. The winner shade was stuck 1/4 open. I received the best of both worlds. The morning sun was able to come in and blind the screen i was trying to use while at the same time it was too low to look out and enjoy the view. Rather embarrassing for a 1st class ticket.

Perfect flight. Smooth flight. Arrived 20 minutes early at destination. Excellent service.

The flights were on time which was great give. It was holiday travel season and there’d been some weather issues. The only complaint and this is every time with United is the terrible seat design. The head rest is not built for comfort and having my neck bent forward for a cross country trip reminded me while I try not to take United flights as a rule.

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

The flight was delayed by two de-icings. The seatbelt did not work correctly. It did not stay tight.

Everything was absolutely wonderful from check in to baggage claim. Staff was very professional and sweet. Will definitely recommend United to family and friends.

Aircraft was noisy, old and never dimmed the lights on a night flight even on business class! I flew 17 times on United and probably another 40 on other airlines United USA /Europe flights were the worst to include luggage delayed once going to europe and once coming back

Check how old the airframe is, some older ones have inoperable seat back entertainment or power.

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

The flight was on time and arrived early. The crew were friendly and helpful.

My carry on baggage was damaged. Entire trip, I had to carry the baggage. When complained to the boarding crew, they got mad at me and still asked me to valet check in the cabin baggage. Rude boarding crew!!!

The economy seats are very cramped and the food was bizarre. However, I did like the greek yogurt option for breakfast.

While I didn’t watch much tv I would have liked a few more options of TV series from Apple TV or hbo max ..

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

Nothing to write home about, average flight experience. Seats were spacious enough, crew friendly enough. Loved the AA entertainment/wifi service.

Kayak was among the missing. There was not the usual advice regarding next gate after arriving in Dallas. No communication after the reminder to check in before the Moline flight. What happened?

They should have allowed for extra time to de-ice the plane before boarding passengers. This delayed us about 10-15 mins after we boarded. Overall experience was fine. Crew was friendly and on top of everything. We didn’t have any issues during the flight.

Experience was good. We were delayed in leaving by 15 mins because the flight was waiting on a family that was late in getting to the gate. Food and drink options were as expected. I highly recommend checking in ahead of time using the airline’s app so that it’s quicker to get your luggage tags as soon as you arrive at the terminal. No more waiting in long lines!

Everything you need to know for your flight from Indianapolis to Panama

Information on your arrival and departure airports