$375 Find Cheap Flights from Panama to Indianapolis - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Indianapolis departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Panama to Indianapolis

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to Indianapolis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to Indianapolis

Thu, Nov 5 - Tue, Nov 10
United Airlines Logo
4:41 pm - 12:44 pmPTY  Panama City Tocumen Intl-IND Indianapolis
20h 03m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
6:33 pm - 8:02 pmIND  Indianapolis-PTY Panama City Tocumen Intl
25h 29m2 stops Chicago O'Hare Intl Newark
$604United Airlines
Thu, Nov 5 - Tue, Nov 10
United Airlines Logo
4:41 pm - 11:19 pmPTY  Panama City Tocumen Intl-IND Indianapolis
30h 38m1 stop Houston George Bush Intcntl
United Airlines Logo
6:33 pm - 8:02 pmIND  Indianapolis-PTY Panama City Tocumen Intl
25h 29m2 stops Chicago O'Hare Intl Newark
$604United Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
3:30 pm - 10:48 amPTY  Panama City Tocumen Intl-IND Indianapolis
18h 18m1 stop Houston George Bush Intcntl
United Airlines Logo
9:00 am - 7:31 pmIND  Indianapolis-PTY Panama City Tocumen Intl
11h 31m1 stop Newark
$613United Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
3:30 pm - 10:48 amPTY  Panama City Tocumen Intl-IND Indianapolis
18h 18m1 stop Houston George Bush Intcntl
United Airlines Logo
7:01 pm - 2:14 pmIND  Indianapolis-PTY Panama City Tocumen Intl
20h 13m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$618United Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
3:30 pm - 4:34 pmPTY  Panama City Tocumen Intl-IND Indianapolis
24h 04m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
8:10 am - 7:31 pmIND  Indianapolis-PTY Panama City Tocumen Intl
12h 21m2 stops Chicago O'Hare Intl Newark
$618United Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
3:30 pm - 10:48 amPTY  Panama City Tocumen Intl-IND Indianapolis
18h 18m1 stop Houston George Bush Intcntl
United Airlines Logo
9:00 am - 7:31 pmIND  Indianapolis-PTY Panama City Tocumen Intl
11h 31m1 stop Newark
$635United Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
3:30 pm - 10:48 amPTY  Panama City Tocumen Intl-IND Indianapolis
18h 18m1 stop Houston George Bush Intcntl
United Airlines Logo
7:01 pm - 2:14 pmIND  Indianapolis-PTY Panama City Tocumen Intl
20h 13m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$639United Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
3:30 pm - 12:42 pmPTY  Panama City Tocumen Intl-IND Indianapolis
20h 12m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
7:01 pm - 7:31 pmIND  Indianapolis-PTY Panama City Tocumen Intl
25h 30m2 stops Chicago O'Hare Intl Newark
$639United Airlines
Thu, Nov 5 - Tue, Nov 10
American Airlines Logo
3:13 pm - 10:58 pmPTY  Panama City Tocumen Intl-IND Indianapolis
7h 45m1 stop Miami
American Airlines Logo
4:30 pm - 2:13 pmIND  Indianapolis-PTY Panama City Tocumen Intl
21h 43m1 stop Miami
$673American Airlines
Thu, Nov 5 - Tue, Nov 10
Avianca Logo
7:50 pm - 2:30 pmPTY  Panama City Tocumen Intl-IND Indianapolis
42h 40m2 stops San Salvador El Salvador Intl Washington, D.C. Dulles Intl
Avianca Logo
5:45 am - 2:55 pmIND  Indianapolis-PTY Panama City Tocumen Intl
33h 10m3 stops Washington, D.C. Dulles Intl Guatemala City La Aurora San José Juan Santamaria Intl
$1,172Avianca
Booking Insights

KAYAK's insights & trends for flights to Indianapolis

Get data-powered insights and trends for flights to Indianapolis to help you find the cheapest flights, the best time to fly and much more.

What are the most popular airlines flying to Indianapolis?

The most popular airline among KAYAK users flying to Indianapolis is United Airlines, followed by Copa Airlines.

Good to know

Low season

June

Cheapest flight

$375
Best time to beat the crowds but there is an average 30% increase in price.
Most popular time to fly and prices are also 17% lower on average.
Flight from Panama City to Indianapolis

FAQs - booking Indianapolis flights

  • How far is Indianapolis Airport from central Indianapolis?

    The distance between Indianapolis Airport and downtown Indianapolis is 8 miles.

  • What is the name of Indianapolis’s airport?

    When flying to Indianapolis, you'll arrive at Indianapolis Airport (IND). The airport is also known as Indianapolis or Indianapolis Intl.

  • How does KAYAK find such low prices on flights to Indianapolis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to Indianapolis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to Indianapolis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Indianapolis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to Indianapolis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Indianapolis with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to Indianapolis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Indianapolis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many direct flights to Indianapolis are there each week?

    Each week there are around 2,704 direct flights from within Panama to Indianapolis. The most common day for departures is Sunday, with 17% of flights taking off on this day.

Top tips for finding cheap flights to Indianapolis

  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest Indianapolis flight deals.

Reviews of the top airlines flying from Panama to Indianapolis

 
See real verified KAYAK customer reviews for airlines flying to Indianapolis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to Indianapolis. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to Indianapolis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1559 reviews
7.8Boarding
6.9Food
8.1Crew
7.4Comfort
6.8Entertainment
Airline reviews

Flight Crew Review The crew was absolutely amazing from start to finish! They were friendly, professional, attentive, and genuinely made the flight feel comfortable and enjoyable. Every interaction was pleasant, and they went above and beyond to make sure passengers were taken care of. You could really tell that they cared about providing great service. I truly appreciate their kindness and professionalism and would be happy to fly with this crew again!

10.0 ExcellentAnonymous, Aug 2026
Read more Copa Airlines reviews

Flight Crew Review The crew was absolutely amazing from start to finish! They were friendly, professional, attentive, and genuinely made the flight feel comfortable and enjoyable. Every interaction was pleasant, and they went above and beyond to make sure passengers were taken care of. You could really tell that they cared about providing great service. I truly appreciate their kindness and professionalism and would be happy to fly with this crew again!

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Some of the Air hostesses are not that friendly. Need improvement

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

Very kind Lufthansa agent somehow gave us all no charge extra business class seats and helped us get home rested and happy.

The lounge was not accessible because it was located before the passport control, and backtracking was impossible.

Onboard staff was courteous, helpful, responsive and friendly. The boarding process was disorganized, poorly communicated, and disheveled. Gate agents were yelling instead of using the PA system, didn’t communicate the timing delay of our flight, and created an atmosphere of chaos rather than order and communication. As far as I know, there was no reason for their. I would hate to see how it operated under extreme conditions. I’ve never seen United Airlines operations in such a state.

It was extremely hot in the cabin the entire flight, vent air was worn

It was terrible. sat on airplane 2 hours then flight was canceled. made to pick up bags and go through Panama immagration to rebook another flight. worst experice ever at a airport.

Crew was tired as we all were. Pretty abrupt. Flight was delayed. Not as enjoyable as the other 3 legs we flew.

Good until I was put on air canada flight Houston Vancouver not even one cookie

More racist flight attandants maybe because i sm an attracticted darkskin latino man but once again bad flight attamdants they ignored me the whole flight even the woman sitting next to me notice how rude they were towards me i really never want to fly united or american airlines they alawsys have the rudesslt and racist flight attandants

The check in from Panama to Houston was good. From Houston to Toronto was definitely an experience. The Pilot from Houston to Toronto was exceptional. He probably saved our lives by noticing a dent in the fuselage. Everyone was taken off the plane and we boarded a new plane

Flight was on time. Staff were friendly. I paid for Economy Plus but was required to check my standard carry-on luggage due to lack of space on the aircraft. This cost me 30 minutes, unexpectedly, in waiting at the baggage claim. This experience did not meet my expectations.

Traveling to a place near Indianapolis?

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Everything you need to know for your flight to Indianapolis

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