$378 Find Cheap Flights from Panama to Indianapolis - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama to Indianapolis

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to Indianapolis

Thu, Dec 17 - Wed, Dec 30
United Airlines Logo
11:55 pm - 1:05 pmPTY  Panama City Tocumen Intl-IND Indianapolis
13h 10m2 stops Newark Chicago O'Hare Intl
United Airlines Logo
5:10 pm - 7:38 pmIND  Indianapolis-PTY Panama City Tocumen Intl
26h 28m1 stop Houston George Bush Intcntl
$658United Airlines
Tue, Dec 15 - Mon, Jan 18
United Airlines Logo
8:55 am - 8:01 pmPTY  Panama City Tocumen Intl-IND Indianapolis
11h 06m1 stop Houston George Bush Intcntl
United Airlines Logo
8:00 pm - 8:02 pmIND  Indianapolis-PTY Panama City Tocumen Intl
24h 02m2 stops Chicago O'Hare Intl Newark
$658United Airlines
Tue, Dec 15 - Mon, Jan 18
United Airlines Logo
4:41 pm - 4:26 pmPTY  Panama City Tocumen Intl-IND Indianapolis
23h 45m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
7:00 am - 7:38 pmIND  Indianapolis-PTY Panama City Tocumen Intl
12h 38m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$658United Airlines
Thu, Dec 17 - Wed, Dec 30
United Airlines Logo
4:41 pm - 3:44 pmPTY  Panama City Tocumen Intl-IND Indianapolis
23h 03m1 stop Houston George Bush Intcntl
United Airlines Logo
5:10 pm - 7:38 pmIND  Indianapolis-PTY Panama City Tocumen Intl
26h 28m1 stop Houston George Bush Intcntl
$658United Airlines
Tue, Dec 15 - Mon, Jan 18
American Airlines Logo
3:13 pm - 11:18 pmPTY  Panama City Tocumen Intl-IND Indianapolis
8h 05m1 stop Miami
American Airlines Logo
7:20 pm - 1:26 pmIND  Indianapolis-PTY Panama City Tocumen Intl
18h 06m1 stop Miami
$667American Airlines
Fri, Jan 8 - Mon, Jan 11
Delta Logo
8:00 am - 3:29 pmPTY  Panama City Tocumen Intl-IND Indianapolis
7h 29m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 2:04 pmIND  Indianapolis-PTY Panama City Tocumen Intl
8h 04m1 stop Atlanta Hartsfield-Jackson
$783Delta
Fri, Nov 20 - Fri, Nov 27
Multiple Airlines Logo
6:15 pm - 6:35 pmPTY  Panama City Tocumen Intl-IND Indianapolis
24h 20m2 stops Miami Atlanta Hartsfield-Jackson
Multiple Airlines Logo
6:53 pm - 8:19 pmIND  Indianapolis-PTY Panama City Tocumen Intl
25h 26m1 stop Fort Lauderdale
$805Multiple Airlines
Fri, Nov 20 - Fri, Nov 27
Multiple Airlines Logo
12:03 pm - 10:41 pmPTY  Panama City Tocumen Intl-IND Indianapolis
10h 38m1 stop Fort Lauderdale
Multiple Airlines Logo
10:56 am - 8:19 pmIND  Indianapolis-PTY Panama City Tocumen Intl
9h 23m1 stop Fort Lauderdale
$822Multiple Airlines
Fri, Nov 20 - Thu, Dec 3
Copa Airlines Logo
8:55 am - 11:19 pmPTY  Panama City Tocumen Intl-IND Indianapolis
14h 24m1 stop Houston George Bush Intcntl
Copa Airlines Logo
6:00 am - 8:02 pmIND  Indianapolis-PTY Panama City Tocumen Intl
14h 02m1 stop Newark
$852Copa Airlines
Fri, Nov 20 - Thu, Dec 3
Copa Airlines Logo
10:00 am - 11:56 pmPTY  Panama City Tocumen Intl-IND Indianapolis
13h 56m2 stops Newark Chicago O'Hare Intl
Copa Airlines Logo
10:20 am - 8:02 pmIND  Indianapolis-PTY Panama City Tocumen Intl
9h 42m1 stop Newark
$857Copa Airlines
Booking Insights

KAYAK's insights & trends for flights to Indianapolis

Get data-powered insights and trends for flights to Indianapolis to help you find the cheapest flights, the best time to fly and much more.

What are the most popular airlines flying to Indianapolis?

The most popular airline among KAYAK users flying to Indianapolis is United Airlines, followed by Copa Airlines.

Good to know

Low season

June

Cheapest flight

$378
Best time to beat the crowds but there is an average 22% increase in price.
Most popular time to fly with an average 6% increase in price.
Flight from Panama City to Indianapolis

FAQs - booking Indianapolis flights

  • How far is Indianapolis Airport from central Indianapolis?

    The distance between Indianapolis Airport and downtown Indianapolis is 8 miles.

  • What is the name of Indianapolis’s airport?

    When flying to Indianapolis, you'll arrive at Indianapolis Airport (IND). The airport is also known as Indianapolis or Indianapolis Intl.

  • How does KAYAK find such low prices on flights to Indianapolis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to Indianapolis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to Indianapolis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Indianapolis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to Indianapolis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Indianapolis with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to Indianapolis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Indianapolis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many direct flights to Indianapolis are there each week?

    Each week there are around 3,114 direct flights from within Panama to Indianapolis. The most common day for departures is Sunday, with 17% of flights taking off on this day.

Top tips for finding cheap flights to Indianapolis

  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest Indianapolis flight deals.

Reviews of the top 3 airlines serving from Panama to Indianapolis

 
Need help choosing which airline to fly with to Indianapolis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8681 reviews
8.1Boarding
8.5Crew
7.8Entertainment
7.8Comfort
7.2Food
Airline reviews

Bad. Flight was delayed due to maintenance issue with Delta. Seats were small, no service, bag got broken on initial flight. Cramped and hot. Sitting inside with no ac.

2.0 MediocreBrandon, Oct 2026
Read more Delta reviews

Bad. Flight was delayed due to maintenance issue with Delta. Seats were small, no service, bag got broken on initial flight. Cramped and hot. Sitting inside with no ac.

Flight attendent didn't let me sit in the empty window seat literally next to me. Doors had closed already so I moved over. She came over, asked for my ticket and made me switch back to the middle. The man on the aisle and I were right on top of each other. Seemed like a real power trip for no reason at all.

The flight was delayed and passengers were told that they will miss connections as flight may get 40-55 min late.

The flight from Atlanta to Tallahassee was delayed, not such a big deal because it arrived almost the same original time. Most of my complaint is that one of the boarding agents and one of the flight attendants seemed bothered and were not very friendly.

Be on time. No issues with weather etc. entirely on airline.

Good flight — left on time due to on time arrival of Pittsburgh flight

Totally organized, quick boarding, professional staff and ON TIME! Good size seats in the cabin Wonderful experience

Two delays on two separate planes with parts they could not easily find and replace.

No entertainment. Plane was so small had to pink tag a carry on ive used for 20 years easily on board. The fact the flight got in at midnight, had to wait for crew in fort wayne to allow the plane to approach the gate, THEN had to wait for bag on jet bridge made experience irritating at best.

We requested wheelchair assistance at ATL. This request was booked in advance of travel, we have requested this service before. We have had issues with accommodations for accessibility in the past, but this was beyond not having a chair on the ramp. We arrived in ATL international gates and had to search for a wheelchair for 40 mins. There were no delta or airport employees available to help. No service phones, nothing. With the help of another passenger I was able to get my elderly mother from the plane to the gate seating bench. She was able to wait there while I searched for a wheel chair.

We were made to check our carry-on luggage because it did not fit the measurements. That’s what we were told, but I saw plenty of carry-on luggage on the plane that was the same size as ours

Flight Crew Review The crew was absolutely amazing from start to finish! They were friendly, professional, attentive, and genuinely made the flight feel comfortable and enjoyable. Every interaction was pleasant, and they went above and beyond to make sure passengers were taken care of. You could really tell that they cared about providing great service. I truly appreciate their kindness and professionalism and would be happy to fly with this crew again!

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Some of the Air hostesses are not that friendly. Need improvement

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Seats needs to be wirer and food is very poor

Kayak booked this flight with only 1h 20min layover in Chicago. This made it impossible for me and several other passengers to reach this flight. Moreover, the gate closed boarding in spite of several passengers still on their way without waiting even one more minute. However, the plane departed with 20min (!) delay, i.e., there would have been at least 15 min time to let the delayed passengers board without causing any delays. I complained and as a "thank you" the attendent booked us on the last (!) flight to Indianapolis ~7h later! Thankfully, I caught the spitefulness and the United customer line rebooked the flight to an earlier flight. Although I can't grade this particular flight since I never had a chance to take it, Kayak made the mistake of a too short layover and the crew at the gate was awful.

Onboard staff was courteous, helpful, responsive and friendly. The boarding process was disorganized, poorly communicated, and disheveled. Gate agents were yelling instead of using the PA system, didn’t communicate the timing delay of our flight, and created an atmosphere of chaos rather than order and communication. As far as I know, there was no reason for their. I would hate to see how it operated under extreme conditions. I’ve never seen United Airlines operations in such a state.

It was extremely hot in the cabin the entire flight, vent air was worn

It was terrible. sat on airplane 2 hours then flight was canceled. made to pick up bags and go through Panama immagration to rebook another flight. worst experice ever at a airport.

Crew was tired as we all were. Pretty abrupt. Flight was delayed. Not as enjoyable as the other 3 legs we flew.

Good until I was put on air canada flight Houston Vancouver not even one cookie

More racist flight attandants maybe because i sm an attracticted darkskin latino man but once again bad flight attamdants they ignored me the whole flight even the woman sitting next to me notice how rude they were towards me i really never want to fly united or american airlines they alawsys have the rudesslt and racist flight attandants

The check in from Panama to Houston was good. From Houston to Toronto was definitely an experience. The Pilot from Houston to Toronto was exceptional. He probably saved our lives by noticing a dent in the fuselage. Everyone was taken off the plane and we boarded a new plane

Flight was on time. Staff were friendly. I paid for Economy Plus but was required to check my standard carry-on luggage due to lack of space on the aircraft. This cost me 30 minutes, unexpectedly, in waiting at the baggage claim. This experience did not meet my expectations.

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Carmel
Anderson
Franklin
Speedway
Mooresville
Carlisle

More options for your flight to Indianapolis