$218 Find Cheap Flights from Indianapolis to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Indianapolis to South America departing on 7/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy, 0 bags

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Cheap Flights from Indianapolis to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$562
Bogotá
Bogotá1 stop$609
Sao Paulo
Sao Paulo2 stops$722
Santiago
Santiago1 stop$1,083
Cartagena
Cartagena1 stop$572
Quito
Quito1 stop$687
Guayaquil
Guayaquil1 stop$472
Cali
Cali2 stops$582
Cusco
Cusco2 stops$1,174
Lima
Lima1 stop$562
Bogotá
Bogotá1 stop$609
Sao Paulo
Sao Paulo2 stops$722
Santiago
Santiago1 stop$1,083
Cartagena
Cartagena1 stop$572
Quito
Quito1 stop$687
Guayaquil
Guayaquil1 stop$472
Cali
Cali2 stops$582
Cusco
Cusco2 stops$1,174

Book Cheap Indianapolis to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Indianapolis to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Indianapolis to South America

Thu, Dec 3 - Mon, Dec 7
Air Canada Logo
6:45 pm - 6:10 am
IND
-
LIM
11h 25m
1 stop
Air Canada Logo
8:00 am - 6:05 pm
LIM
-
IND
34h 05m
2 stops
$562Air Canada
Thu, Dec 3 - Mon, Dec 7
Air Canada Logo
6:45 pm - 3:15 am
IND
-
LIM
32h 30m
2 stops
Air Canada Logo
8:00 am - 6:05 pm
LIM
-
IND
34h 05m
2 stops
$566Air Canada
Wed, Aug 19 - Sat, Aug 29
American Airlines Logo
6:00 am - 2:15 pm
IND
-
CTG
9h 15m
1 stop
American Airlines Logo
1:35 pm - 11:38 am
CTG
-
IND
21h 03m
2 stops
$572American Airlines
Wed, Dec 2 - Thu, Dec 3
LATAM Airlines Logo
8:00 pm - 6:10 pm
IND
-
CLO
22h 10m
2 stops
LATAM Airlines Logo
8:20 pm - 5:00 pm
CLO
-
IND
20h 40m
2 stops
$582LATAM Airlines
Thu, Aug 6 - Thu, Aug 13
American Airlines Logo
6:48 pm - 12:35 pm
IND
-
CTG
18h 47m
2 stops
American Airlines Logo
1:35 pm - 10:27 am
CTG
-
IND
19h 52m
2 stops
$592American Airlines
Mon, Sep 7 - Tue, Sep 22
Delta Logo
6:00 am - 7:15 pm
IND
-
BOG
14h 15m
1 stop
Delta Logo
2:55 pm - 12:35 am
BOG
-
IND
8h 40m
1 stop
$619Delta
Wed, Sep 9 - Thu, Sep 24
Delta Logo
10:41 am - 6:45 pm
IND
-
BOG
9h 04m
2 stops
Delta Logo
2:55 pm - 12:35 am
BOG
-
IND
8h 40m
1 stop
$624Delta
Tue, Aug 18 - Wed, Sep 9
LATAM Airlines Logo
7:02 am - 5:05 am
IND
-
MDE
23h 03m
2 stops
LATAM Airlines Logo
7:45 am - 12:35 am
MDE
-
IND
15h 50m
2 stops
$635LATAM Airlines
Sun, Jul 26 - Sun, Aug 2
GOL Logo
6:40 pm - 1:17 pm
IND
-
CLO
19h 37m
1 stop
GOL Logo
11:59 pm - 6:28 pm
CLO
-
IND
17h 29m
2 stops
$776GOL
Fri, Aug 21 - Sun, Aug 30
GOL Logo
6:00 am - 7:15 am
IND
-
BSB
24h 15m
1 stop
GOL Logo
9:55 am - 11:52 pm
BSB
-
IND
14h 57m
1 stop
$836GOL
Booking Insights

KAYAK's insights & trends for Indianapolis to South America flights

Get data-powered insights and trends into flights from Indianapolis to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Indianapolis to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Indianapolis to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Indianapolis to South America is December, when tickets cost $129 (return) on average. On the other hand, the most expensive months are May and June, when the average cost of round-trip tickets is $555 and $429 respectively.

How far in advance should I book a flight from Indianapolis to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Indianapolis to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Indianapolis to South America, you should book around 4 weeks before departure, which saves you about 26% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 16 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$218
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly with an average 15% increase in price.
Flight from Indianapolis to Cali

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Indianapolis to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Indianapolis to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Indianapolis to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Indianapolis to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Indianapolis to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Indianapolis to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Indianapolis to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Indianapolis to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Indianapolis to South America

 
Need help choosing which airline to fly with from Indianapolis to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8424 reviews
7.2Food
8.1Boarding
7.8Entertainment
8.5Crew
7.8Comfort
Airline reviews

Very good flight. Crew was great. No issues and we even arrived early.

10.0 ExcellentAnonymous, Jun 2026
SAN - DTW
Read more Delta reviews

Very good flight. Crew was great. No issues and we even arrived early.

The flights are constantly late anymore, and they won't even give you a glass of water on the plane. For years, they were able to do a service on this flight from Atlanta to Knoxville and Knoxville Atlanta now they say it's too short of a flight. You can't even get a quick drink of water.

Flight got canceled 4 times, missed my connecting flight due to delays, have to wait to go home tomorrow

Third flight in two months where the crew was not there. Comfort seating does not guarantee overhead bin space. Passengers with children are allowed on the plane first - if you are flying to and from Orlando, this means half the plane has boarded before you get on. And somehow all the bin space is taken up. 3 out of 5 flights have had issues with equipment or procedure. Some of these instances caused the flight to be delayed because of a "nuisance" light. One time it was a bag that had been brought on board but did not belong to anyone so we had to return to the gate. Last night we were told the "AC" on the plane doesn't work well and we're 10th for take off- because the crew was late - and that it will get cool when we're in the air. Not sure if this is usual, but I didn't think flight crew could jump seat in first class. Movie and TV selection has not been refreshed for several months- flying one to two round trips each month easily exhausts the list of content.

Great experience nice pilot very soft and easy landing and take off

We sat on the runway for over an hour before departure. That was unwelcome.

Horrible. Faucet in sink not working, wifi not working. Didn’t bring food or snacks

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

From checking to boarding, it was a seamless experience. The service agents were so helpful. The flight crew was so pleasant.

Gate agent showed up 20 minutes before boarding and was not at all friendly. Had to take this flight due to the one on the day before being cancelled and any later options were already full with long standby lists. Despite having paid for Delta Comfort seats, Delta did not allow me (or anyone) to choose their seat. The agent assigned them for everyone just prior to boarding. Self seat selection was allowed on the original flight. Flight staff was great - very friendly.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Great experience. Boarding was fast, staff were very nice and funny, everything at the seat worked well.

Boarding was great, and the crew were very friendly. The seats must have been a bit on the older side and you could feel some of the seat components through the padding. Also, the plugs did not work on the row's entertainment screen or charging ports. Checked bag was transferred for connecting flight, and we appreciated how early we had the connecting gate information.

Lost one piece of luggage even though I checked in 2.5 hours before the flight

It was Swiss. Our kosher meals were literally frozen solid and therefore inedible, and the crew didnt care.

For the expense of first class, the seats could have been nicer and higher tier snacks would have been nice.

The boarding process on the departure from LA was rather slow even though I was in Group 1. For first class, I was not expecting to have to pay for Wi-fi but I did and then the wi-fi was spotty. The entree was surprisingly good and so that was a pleasant surprise. However, once I got to Houston, it was terrible. Unfortunately there was bad weather but the constant gate changes for my connecting flight was difficult to manage due to having to navigate back and forth between different terminals.

We used Kayak to reserve our tickets and specifically checked the luggage option which was a more expensive option. When we arrived at the terminal we had to pay an extra $90 per suitcase for the three passengers. This has been a pattern for the past 3 years. Why charge for a more expensive luggage option, and the ticket price not include luggage?

They delayed the flight 3 hours because it wasn't full they moved us to 5 different gates probably the worst airline ever not even spirit is this bad.

Very easy ! Use the kiosk and bag drop and right to security within 10 min

Checking bag at terminal was horrible. No agents to check us in and only 1 kiosk working. Boarding went ok. Crew onboard was very scattered rained. Missed our row while serving and then didn’t see them hardly again.

Was given all 3 boarding passes. Was refused boarding to Brasilia in Miami even though I had up to date Brazilian Visa and US passport. Had to return to Phoenix as trip was cancelled. Waiting for refund of the fare. Missed my son's birthday and visit with him and his wife.

The pilots landing and taking off was very bad on the first flight, the second one taking off was great but landing was also rough

The check in and on the ground experience is very poor. Their online check and trip management is the worst I have ever seen and they have long lines to check in at the airport, technology is glitchy/unusable and have exorbitant baggage fees. The flight itself is fine, although the food is about what you would expect and their was no functioning entertainment for an international flight.

My experience with this flight was extremely negative and resulted in serious financial and personal consequences. The flight departed with a significant delay, which caused me to miss my international connecting flight. As a direct result of this delay — which was entirely beyond my control — I was unable to reach my final destination on time, causing me to lose a previously scheduled hair transplant surgery that had been arranged months in advance. This was not a minor inconvenience. The surgery involved: • A reserved operating room • Medical and technical staff scheduled specifically for that date • Surgical instruments prepared in advance • Strict scheduling that does not allow for easy rescheduling Due to the airline’s delay and poor handling of the situation: • I lost already paid international flight tickets • I was forced to purchase new tickets, incurring duplicate expenses • I spent over six additional hours in airports, under stressful conditions • I incurred unexpected costs for meals and transportation • I lost a medical opportunity that cannot be easily recovered, along with the emotional distress associated with it Although the airline covered one night of hotel accommodation, this did not address the real impact of the delay, nor the significant damages caused by missing a critical medical procedure. The lack of punctuality, planning, and effective solutions reflects a serious lack of responsibility toward passengers, especially when international connections and time-sensitive medical commitments are involved. I do not recommend this airline for travelers with important schedules, medical appointments, or critical connections. In my case, the delay did not merely cause inconvenience — it resulted in the loss of a surgery and substantial financial damage.

I was not able to get on the flight due to delays out of Philadelphia. I arrived in MIA at 10:30pm and there was no one at the GOL Desk. Is there any flight credit available for this flight?

I have a hand injury and the flight attendant denied to help me with luggage, she said "she couldn't help me because I should manage my own way to put the luggage on the plane" SO RUDE

I had two around 6 hours flight and they did not even offer water to us.

Overall it was good. The food was not great quality and seats were very uncomfortable. But overall the staff was very friendly and helpful.

We flew with Avianca, some how they are not n sync, making the process a bit uncomfortable.

Unfortunately it was very disappointed experience. Our first flight our was delayed 2 hours, as a consequence we missed our connecting international flight. Customer server at Miami American Airlines was very disrespectful, gave us the worst replace itenarary for the next day that we had to spend 2 hours calling Gol to get a better itinerary otherwise we wouldn't make it on time to fulfill our trip purpose. We would have missed the reason to travel all the way to Brazil if we didn't change for a better itinerary. The worst thing is that our baggage was missing for 4 days. We had no cloths for all this time, plus the aggravation to locate our baggage. Nobody knew where our baggage was. We ended up picking it up at the airport when they said that they will bring them home. Unfortunately our experience was very dissatisfied.

American Airlines is a great dependable airline, on time arrival and departure with polite crew and staff.

I think since I am an AA Advantage member, my checked bags should have been free, but I paid for all 4 of us.

This flight moved Gates several times in a short time period, from B to C, which required a substantial walk or rail ride. Then the flight was delayed more than 2 hours and the food was subpar compared to other flights.

Flight was delayed multiple times without giving any particular reason and the only thing that was communicated was that 'Aircraft is getting ready'. I was stuck at SFO airport for 15 hours and finally took Southwest Airlines flight back home to Dallas.

Hydraulic leak caused the flight to be cancelled. Auto system scheduled us on a 3 am flight. Wevhsedvrebook on the app and hit schedules later in the afternoon. Our luggage per gate and ticket agent would be rescanned and put in our new flight. Did not happen. Our luggage stayed in hsv. Baggage claim in wash dc unable to help. We filed a claim. Several emails about our luggage were in conflict with one another. Called as baggage and was on hold 30 minutes. Oscar said one of 2 was out fir delivery then cancelled. About 45 minutes later both pieces were delivered. Their system is suspect

I was not clear if food was offered or not.

Because I bought my ticket from Underpricer, I could not check in online. I could only check in at the airport and that was deeply frustrating because I had to arrive very early. The flight also departed 45 min late and passengers were given no explanations about why we were delayed. I was worried I would miss my connecting flight. Once on board, however, the flight was fine.

Absolutely terrible. They boarded the plane, supposedly realized they didn't refuel the plane or load the luggage so we sat as the gate inside the plane for over 2 hours while they supposedly did things that should have been done before having passengers board the planem

Flight cancelled. Twice. And no communication. No gate agent. Went past boarding time and had to go and see email from AA. Airport communication was bad

I love the e fact that the staff communicated swiftly when my flight was delayed and gate number changed

Everything you need to know for your flight to South America

Information on your arrival and departure airports