$171 Find Cheap Flights from Indianapolis to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Indianapolis to South America departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Indianapolis to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$594
Bogotá
Bogotá1 stop$313
Sao Paulo
Sao Paulo2 stops$796
Santiago
Santiago2 stops$815
Cartagena
Cartagena1 stop$366
Quito
Quito1 stop$576
Guayaquil
Guayaquil1 stop$455
Cali
Cali2 stops$451
Cusco
Cusco3 stops$848
Lima
Lima2 stops$594
Bogotá
Bogotá1 stop$313
Sao Paulo
Sao Paulo2 stops$796
Santiago
Santiago2 stops$815
Cartagena
Cartagena1 stop$366
Quito
Quito1 stop$576
Guayaquil
Guayaquil1 stop$455
Cali
Cali2 stops$451
Cusco
Cusco3 stops$848

Book Cheap Indianapolis to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Indianapolis to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Indianapolis to South America

Fri, Apr 10 - Sat, Apr 18
Spirit Airlines Logo
5:45 am - 1:11 pm
IND
-
BOG
8h 26m
1 stop
Spirit Airlines Logo
2:07 pm - 11:59 pm
BOG
-
IND
8h 52m
1 stop
$313Spirit Airlines
Fri, Apr 24 - Sun, May 10
Multiple Airlines Logo
6:40 pm - 1:12 pm
IND
-
BOG
19h 32m
1 stop
Multiple Airlines Logo
2:07 pm - 11:23 am
BOG
-
IND
20h 16m
2 stops
$321Multiple Airlines
Tue, Jun 9 - Wed, Aug 19
American Airlines Logo
6:00 am - 11:58 pm
IND
-
UIO
18h 58m
1 stop
American Airlines Logo
6:09 am - 6:42 pm
UIO
-
IND
11h 33m
1 stop
$680American Airlines
Tue, Jun 9 - Wed, Aug 19
American Airlines Logo
12:11 pm - 11:58 pm
IND
-
UIO
12h 47m
2 stops
American Airlines Logo
6:09 am - 12:12 am
UIO
-
IND
17h 03m
2 stops
$685American Airlines
Thu, Jun 18 - Sun, Jul 19
United Airlines Logo
7:00 am - 11:25 pm
IND
-
UIO
17h 25m
1 stop
United Airlines Logo
7:25 am - 4:30 pm
UIO
-
IND
32h 05m
2 stops
$731United Airlines
Thu, Jun 18 - Sun, Jul 19
United Airlines Logo
11:40 am - 5:00 am
IND
-
UIO
18h 20m
2 stops
United Airlines Logo
7:25 am - 4:30 pm
UIO
-
IND
32h 05m
2 stops
$734United Airlines
Thu, Sep 10 - Wed, Sep 23
Air Canada Logo
4:25 pm - 9:05 am
IND
-
GRU
15h 40m
1 stop
Air Canada Logo
9:35 pm - 8:36 pm
GRU
-
IND
24h 01m
1 stop
$884Air Canada
Thu, Sep 10 - Mon, Sep 21
Air Canada Logo
4:25 pm - 9:05 am
IND
-
GRU
15h 40m
1 stop
Air Canada Logo
9:00 pm - 3:41 pm
GRU
-
IND
19h 41m
2 stops
$888Air Canada
Tue, Sep 1 - Tue, Sep 8
LATAM Airlines Logo
4:15 pm - 6:55 am
IND
-
SCL
14h 40m
2 stops
LATAM Airlines Logo
10:55 pm - 4:12 pm
SCL
-
IND
18h 17m
1 stop
$916LATAM Airlines
Tue, Apr 28 - Tue, May 5
LATAM Airlines Logo
12:55 pm - 6:25 am
IND
-
SCL
17h 30m
1 stop
LATAM Airlines Logo
5:40 am - 12:41 am
SCL
-
IND
19h 01m
2 stops
$958LATAM Airlines
Booking Insights

KAYAK's insights & trends for Indianapolis to South America flights

Get data-powered insights and trends into flights from Indianapolis to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Indianapolis to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Indianapolis to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Indianapolis to South America is October, when tickets cost $676 (return) on average. On the other hand, the most expensive months are December and November, when the average cost of round-trip tickets is $1,110 and $871 respectively.

How far in advance should I book a flight from Indianapolis to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Indianapolis to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Indianapolis to South America, you should book around 4 weeks before departure, which saves you about 24% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$171
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Indianapolis to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Indianapolis to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Indianapolis to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Indianapolis to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Indianapolis to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Indianapolis to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Indianapolis to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Indianapolis to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Indianapolis to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Indianapolis to South America

 
Need help choosing which airline to fly with from Indianapolis to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8317 reviews
8.1Boarding
8.5Crew
7.9Comfort
7.8Entertainment
7.2Food
Airline reviews

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

2.0 MediocreAnonymous, Mar 2026
HNL - ATL
Read more Delta reviews

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was cencaled due with the bad weather on Sunday the crew was poorly mistaken my luggage supposed depart with my flight instead I didn’t have my luggage for almost 3 days the website is poorly respond to my complain until I have someone to do it my connection smooth their not even respon or email me even the have my luggage

Delta needs to step its game up get a more reliable internet service. Internet service was non-existent for this flight.

Mechanical Delay of over an hour with multiple gate changes. Entertainment system down for rejuvenation.

This was a Latam operated flight. Seats seemed a bit narrow in business class. Older aircraft.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

8 hours late and the plane smelled like urine, that smell in the morning when your child wet the bed in the night.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

Didn't make the flight because the first leg of my flight was canceled and the next leg was already booked.

My flight was canceled a few hours before boarding. I was rebooked on Copa airlines and missed an important meeting .

Good quick flight on a small but comfortable plane. I'm 6'3 and had plenty of space.

Experience was great - no complaints. Took off on time, landed early. Got to the gate relatively quickly - took a little bit of extra time to deplane but nothing excessive.

Business class seats felt very cramped compared to other airlines.

Economy plus was so cramped I could not use my laptop. It was beyond bad.

OK, we were delayed and had to de plane and reboard.

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

Both our flights were delayed. Almost didn’t get in the second flight. Staff was rude to the bone.

Both my flight where delayed Had 25min to make it to my transfer flight

Absolutely terrible. Would never fly American again. 2 deplaned incidents and delayed by close to 24 hours. $12 meal voucher for first class passengers was an insult to the injury. Pathetic.

Terrible planning. And even worse gate agents. Absolutely rude behavior.

Half of the TSA checkpoints at PHL are closed. Also, there is no standby for first class passengers. You can only standby for coach. Very dated policy and inconsistent with peers.

Flight was scheduled at 11:26am but they keep Delaying until midnight. They waited at airport restless.

Rough flight No beverage service due to turbulence Bottom Seat cushion was non existent

Great experience. Good dinner and service. FA's were very nice and attentive.

It was great. Smooth flight, comfortable, left on time and landed on time.

Perhaps this is an airport issue, but being in a takeoff queue for over an hour in the taxiing lane is unacceptable. We will definitely be seeking alternative avenues for air travel in the future.

We hoarded. Then we deplaned. Then we waited for 10 hours in the MSP airport due to a wheel misfunction. We understand safety but communication between crew and airport staff was horrible. When we did finally board, we were rushed on and because we were waiting for a “fresh” pilot and crew, we sat in a roasting plane with no A/C for an hour. My question is why was this flight not cancelled right away when they knew this would be a huge issue OR, why did AA not get a substitute plane, considering this was already a full flight? To me, this appears to be a complete breakdown in leadership and utter systems failure. The compensation for completely disrupting travel plans for hundreds, which we paid dearly for, was measly. While we appreciated the lodging for the night, $12 in meal vouchers isn’t going to sustain anyone for over 12 hours. “We apologize; our hands are tied” is no longer an acceptable explanation. We are so completely turned off by this experience and will definitely seek alternative avenues when we need to fly.

Mostly good. The WiFi wasn’t working so that was not great.

They cancelled our flight. 2 hours before we were supposed to take off and offered us nothing! We got our money back and that was it. No other flight to get to our cruise no working with another airline or with us to get there. Terrible customer service, no apology.

we boarded the plane and then sat for OVER AN HOUR on it, first waiting for fuel and then the crew timed out. the flight kept getting delayed longer and longer, a 9:30pm flight is still on the ground at 1:15am.

The airplane rattled near the left wing as if several screws were loose. Then after we landed in Fort Lauderdale, we had to sit and wait on the runway for quite some time. It was very scary and TOTALLY unacceptable!

Smooth flight staff very friendly and we arrived 15 mins earlier

I was in the airport when I'll check the status of my flight and it was canceled and without any reason. The worst of the worst ...

I never had an opportunity to experience them! They cancelled my flight TWICE!!!

Return flight was canceled. Needed to reschedule with another airline the next day. Cost an an additional $84. At another airport 45 miles further away

Spent seven hours in the airport with spirit pushing he flight time back two hours every two hours only to then have it canceled without explanation. The employees said, “They’ve been doing this for the last five days.” Would have been great if they told us to expect that when we arrived.

Seat do not reclined and tight space. Flight changed so many times hard to keep up.

Bad airline to travel with my flight was delayed for more than 3 hours they act like it’s normal

Everything you need to know for your flight to South America

Information on your arrival and departure airports