$125 Find Cheap Flights from Iowa to Mississippi

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Good to know

Low seasonJanuary
High seasonNovember
Cheapest flight$125
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Des Moines to Memphis

FAQs for booking flights from Iowa to Mississippi

  • How does KAYAK find such low prices on flights from Iowa to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Iowa to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Iowa to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Iowa to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Iowa to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Iowa to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Iowa to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Iowa to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest day to fly to Mississippi?

    Based on KAYAK data, the cheapest day to fly to Mississippi is Saturday where round-trip tickets can be as cheap as $296. On the other hand, the most expensive day to fly is Wednesday, where round-trip prices are $508 on average.

  • What is the cheapest time of day to fly to Mississippi?

    The cheapest time of day to fly to Mississippi is generally in the evening, when round-trip flights cost $296 on average. Morning departures are around 27% more expensive than evening flights, on average. The most expensive time of day to fly to Mississippi is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $560.

  • What is the cheapest month to fly from Iowa to Mississippi?

    The cheapest month for flights from Iowa to Mississippi is January, when tickets cost $253 (return) on average. On the other hand, the most expensive months are February and December, when the average cost of round-trip tickets is $443 and $443 respectively.

  • How long is the flight to Mississippi?

    An average nonstop flight from Iowa to Mississippi takes 7h 30m, covering a distance of 747 miles. The shortest route is Omaha (OMA) to Memphis (MEM) with an average flight time of 4h 25m.

  • What are the most popular destinations in Mississippi?

    Based on KAYAK flight searches, the most popular destination is Mobile (39% of total searches to Mississippi). The next most popular destinations are Baton Rouge (24%) and Memphis (21%). Searches for flights to Gulfport (7%), to Alexandria (4%) and to Jackson (3%) are also popular.

Top airlines flying from Iowa to Mississippi

 
Need help choosing which airline to fly with from Iowa to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7950 reviews
7.3Food
8.2Boarding
8.5Crew
7.9Entertainment
7.9Comfort
Airline reviews

Great service. Flight was delayed while we sat on the runway for a couple of hours. Weather related. Staff made is very bearable. The steward servicing the first class cabin was exceptional. Thank you! 💗

10.0 ExcellentHartaj, Jun 2025EWR - RDU
Read more Delta reviews

Great service. Flight was delayed while we sat on the runway for a couple of hours. Weather related. Staff made is very bearable. The steward servicing the first class cabin was exceptional. Thank you! 💗

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

My flight was 6 pm 6/6. Every hour they delayed it again - air condition issues then no pilot then the crew had worked too many hours and cancelled the flight at 11 pm. Sent customers to NJ a 45 minutes uber ride to a hotel. Had to be back by 5 am for a 7 am flight and again no pilot etc with another three hours of delays.

The entertainment and wifi mostly didn't work on this flight.

Terrible entertainment system - kept freezing and audio kept cutting out. Snacks were mediocre at best for a 5 hour flight.

The check in and bag drop off for Sky Priority members is slow. The Clear security was also slow - a TSA issue.

I am still upset that my bag was lost on a recent trip to Rome ; we were inconvenienced and out €150 Euros ; delta has refused to reimburse us

I am very bothered by the events today. I can't believe the flight attendants allowed someone to take my seat and made me move. It was embarrassing. I was in the right. The lady just didn't want move. I can't believe delta would allow this to stand and disrespect my rights as a passenger. The lady complained about her leg and that she couldn't move. Firstly somehow she was able to make it to row 24. Not sure how much her leg could have hurt. Secondly, I'm in plenty of pain myself. I just finished chemotherapy a several weeks ago. My body is constantly sore. Yet deltas flight attendants didn't appropriately protect my rights. In the end they found me a seat on the plane but I want to understand how delta can operate this way. They in essence allowed a bully to get their way.

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

Most miserable flight ever. We waited almost 2 hours on the runway because the flight was oversold. American offered $1200 credit. Then there was some nonsense about weight distribution. Ridiculous. No food for 8 plus hours on the flight. I will be writing a letter.

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

The plane was probably full boarding was easy. We were able to check our carry-on luggage for free. It was a return flight through Philly to LA. Never saw a stewardess do a demonstration of emergency Procedures. I think my flight was pretty full

Plane, flight, crew, captain were all great. The first flight had a Chipotle box lunch...delicious.

Plane, flight, crew, captain were all great. The first flight had a Chipotle box lunch...delicious. this return flight not as tasty, but filling.

The flight was 2 hour delayed, otherwise everything was excellent. The delay was due to the hourly limit requirement so given that as a reason, I'm happy with the flight!

Weather delay for 2.5 hours followed by half hour crew delay, did not have ginger ale, uncomfortable seats

So awful Unreliable Unfriendly Bad Mad Mean Smelly Hot Late Overbooked Understaffed Expensive Cramped Narcs If they were a fruit they’d be rotten durian

It’s a great flight. Service is good. Staff is awesome.

Book cheap flights from Iowa to Mississippi

Recent round-trip flight deals

10/20Mon
1 stopAmerican Airlines
11h 37mOMA-MEM
10/23Thu
1 stopAmerican Airlines
8h 16mMEM-OMA
$225
7/4Fri
2 stopsAmerican Airlines
8h 44mOMA-GPT
7/11Fri
1 stopAmerican Airlines
5h 58mGPT-OMA
$229
7/4Fri
1 stopDelta
7h 08mOMA-GPT
7/11Fri
1 stopDelta
6h 12mGPT-OMA
$243
8/26Tue
1 stopUnited Airlines
6h 39mDSM-MEM
8/27Wed
1 stopUnited Airlines
4h 53mMEM-DSM
$246
9/4Thu
1 stopDelta
6h 17mMLI-MOB
9/6Sat
1 stopDelta
7h 07mMOB-MLI
$249
6/26Thu
1 stopUnited Airlines
5h 17mOMA-BTR
6/30Mon
1 stopUnited Airlines
7h 28mBTR-OMA
$259
8/26Tue
2 stopsSouthwest
9h 00mDSM-MEM
8/27Wed
2 stopsSouthwest
6h 50mMEM-DSM
$261
10/20Mon
1 stopSouthwest
7h 45mOMA-MEM
10/23Thu
2 stopsSouthwest
8h 30mMEM-OMA
$268
7/7Mon
1 stopAllegiant Air
21h 46mDSM-MEM
7/10Thu
1 stopAllegiant Air
11h 52mMEM-DSM
$272
7/28Mon
1 stopAllegiant Air
11h 25mOMA-MEM
7/31Thu
1 stopAllegiant Air
27h 56mMEM-OMA
$275

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Recent one-way flight deals

7/9Wed
1 stopAmerican Airlines
6h 49mDSM-MEM
$125
7/9Wed
2 stops
30h 16mDSM-MEM
$142
7/9Wed
3 stops
20h 37mDSM-MEM
$175
7/30Wed
1 stopDelta
6h 30mDSM-MOB
$210
7/30Wed
2 stopsDelta
7h 38mDSM-MOB
$215
6/19Thu
2 stops
22h 59mDSM-MEM
$230
6/24Tue
1 stopAmerican Airlines
5h 42mOMA-BTR
$244
6/19Thu
1 stop
26h 56mDSM-MEM
$247
6/17Tue
1 stopAllegiant Air
21h 35mOMA-MEM
$264
6/17Tue
2 stopsSouthwest
10h 05mOMA-MEM
$281

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Last minute flights from Iowa to Mississippi

Last minute flight, train and bus deals

6/15Sun
multi-stopAmerican Airlines
4h 43mMLI-MEM
6/23Mon
multi-stopAmerican Airlines
4h 52mMEM-MLI
$279
6/15Sun
multi-stopAmerican Airlines
4h 43mMLI-MEM
7/16Wed
multi-stopAmerican Airlines
9h 07mMEM-MLI
$343
6/14Sat
multi-stopAmerican Airlines
5h 24mMLI-MOB
6/21Sat
multi-stopAmerican Airlines
5h 24mMOB-MLI
$392
6/14Sat
multi-stopDelta
6h 00mMLI-MOB
6/24Tue
multi-stopDelta
4h 54mMOB-MLI
$412
6/14Sat
multi-stopDelta
6h 00mMLI-MOB
6/19Thu
multi-stopDelta
4h 54mMOB-MLI
$452
6/15Sun
multi-stop
22h 10mMLI-MEM
7/16Wed
multi-stop
18h 12mMEM-MLI
$485
6/14Sat
multi-stopAllegiant Air
24h 35mOMA-MEM
6/16Mon
multi-stopAllegiant Air
6h 17mMEM-OMA
$490
6/14Sat
multi-stop
30h 13mDSM-MEM
6/15Sun
multi-stop
11h 47mMEM-DSM
$500
6/14Sat
multi-stopSouthwest
9h 15mDSM-MEM
6/15Sun
multi-stopSouthwest
12h 05mMEM-DSM
$585
6/14Sat
multi-stopSouthwest
9h 05mOMA-MEM
6/16Mon
multi-stopSouthwest
5h 10mMEM-OMA
$601

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Everything you need to know for your flight to Mississippi

Cabin class types available on flights to Iowa

Cabin classes available on flights to Iowa. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

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