$249 Find Cheap Flights from Des Moines to Mississippi

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Mississippi departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mississippi

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Mississippi, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Mississippi, as well as popular online travel agencies
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Cheap Flights from Des Moines to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson1 stop$276
Gulfport
Gulfport1 stop$249
Memphis
Memphis1 stop$251
Jackson
Jackson1 stop$276
Gulfport
Gulfport1 stop$249
Memphis
Memphis1 stop$251

Book Cheap Des Moines to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Mississippi

Wed, Apr 1 - Wed, Apr 8
Delta Logo
5:35 am - 11:55 am
DSM
-
MOB
6h 20m1 stop
Delta Logo
6:00 am - 10:39 am
MOB
-
DSM
4h 39m1 stop
$249Delta
Fri, Jan 9 - Fri, Jan 16
American Airlines Logo
4:25 pm - 10:41 pm
DSM
-
GPT
6h 16m1 stop
American Airlines Logo
5:31 am - 10:50 am
GPT
-
DSM
5h 19m1 stop
$249American Airlines
Wed, Jan 21 - Wed, Jan 28
American Airlines Logo
11:35 am - 6:04 pm
DSM
-
BTR
6h 29m1 stop
American Airlines Logo
7:07 am - 3:45 pm
BTR
-
DSM
8h 38m1 stop
$250American Airlines
Wed, Jan 21 - Wed, Jan 28
Delta Logo
5:16 pm - 11:13 pm
DSM
-
MEM
5h 57m1 stop
Delta Logo
5:50 am - 10:51 am
MEM
-
DSM
5h 01m1 stop
$251Delta
Tue, Jan 6 - Sat, Jan 10
United Airlines Logo
8:00 am - 6:24 pm
DSM
-
MOB
10h 24m2 stops
United Airlines Logo
7:00 am - 2:22 pm
MOB
-
DSM
7h 22m1 stop
$254United Airlines
Wed, Jan 21 - Wed, Jan 28
Delta Logo
5:16 pm - 10:01 pm
DSM
-
BTR
4h 45m1 stop
Delta Logo
1:37 pm - 8:54 pm
BTR
-
DSM
7h 17m2 stops
$254Delta
Wed, Jan 21 - Wed, Jan 28
American Airlines Logo
5:01 pm - 11:07 pm
DSM
-
MEM
6h 06m1 stop
American Airlines Logo
6:35 am - 4:24 pm
MEM
-
DSM
9h 49m2 stops
$257American Airlines
Tue, Jan 6 - Sat, Jan 10
United Airlines Logo
8:00 am - 6:24 pm
DSM
-
MOB
10h 24m2 stops
United Airlines Logo
9:00 am - 8:34 pm
MOB
-
DSM
11h 34m2 stops
$259United Airlines
Wed, Jan 21 - Wed, Jan 28
Delta Logo
6:24 am - 3:59 pm
DSM
-
BTR
9h 35m2 stops
Delta Logo
1:37 pm - 8:54 pm
BTR
-
DSM
7h 17m2 stops
$259Delta
Tue, Jan 27 - Wed, Jan 28
United Airlines Logo
3:04 pm - 9:57 pm
DSM
-
JAN
6h 53m1 stop
United Airlines Logo
5:15 pm - 10:30 pm
JAN
-
DSM
5h 15m1 stop
$293United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Mississippi flights

Get data-powered insights and trends into flights from Des Moines to Mississippi to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to Mississippi?

The average price of all round-trip flights from Des Moines to Mississippi clicked on KAYAK for each day over the last 12 months.

When flying from Des Moines to Mississippi, you should consider leaving on a Saturday and avoid Wednesdays if you are looking for the best rates. For your return to Des Moines, you’ll find the best rates on Saturdays and the most expensive ones on Wednesdays.

Good to know

Low seasonAugust
Cheapest flight$249
Best time to beat the crowds with an average 37% drop in price.
Most popular time to fly with an average 35% increase in price.
Flight from Des Moines to Mobile

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from Des Moines to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Mississippi?

    The cheapest time of day to fly to Mississippi is generally in the evening, when round-trip flights cost $296 on average. Morning departures are around 27% more expensive than evening flights, on average. The most expensive time of day to fly to Mississippi is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $560.

Reviews of the top airline flying from Des Moines to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11046 reviews
8.0Crew
6.9Entertainment
6.5Food
7.5Boarding
7.2Comfort
Airline reviews

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

2.0 MediocreJeremy, Dec 2025
CLT - GNV
Read more American Airlines reviews

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

AA delayed the flight for 3 hours and 50 minutes, but delayed the last 2 hours, 30 minutes at a time, so if we knew before, could have stayed at home and worked instead of being at the airport wasting time... The plane's crew was excellent, not their fault.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

RIC Staff was not enough. Elderly passengers had to wait 30 minutes to deplane, so we could board and still had to walk as no chairs were provided. And, passenger in front of my seat assignment rammed seat against my legs entire flight time. Was mildly bruised and left thigh still sore.

Liked that it was on time. Staff professional and friendly.

Things were delayed a little. But that didn’t affect my plans. It was fine. I was surprised it was so full thanksgiving day. The crew were friendly and professional.

Everything you need to know for your flight from Des Moines to Mississippi

Information on your arrival and departure airports