$107 Find Cheap Flights from Des Moines to Mississippi

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Mississippi departing on 11/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Mississippi

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Mississippi, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Mississippi, as well as popular online travel agencies
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Cheap Flights from Des Moines to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson1 stop$297
Gulfport
Gulfport1 stop$279
Memphis
Memphis1 stop$213
Jackson
Jackson1 stop$297
Gulfport
Gulfport1 stop$279
Memphis
Memphis1 stop$213

Book Cheap Des Moines to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Mississippi

Sat, Jan 17 - Tue, Jan 20
Delta Logo
6:20 am - 11:29 amDSM-MEM
5h 09m1 stop
Delta Logo
6:00 am - 10:22 amMEM-DSM
4h 22m1 stop
$213Delta
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Sat, Jan 17 - Wed, Jan 21
Delta Logo
6:20 am - 11:29 amDSM-MEM
5h 09m1 stop
Delta Logo
6:00 am - 10:23 amMEM-DSM
4h 23m1 stop
$232Delta
Find Deal
Thu, Nov 6 - Fri, Nov 14
American Airlines Logo
4:03 pm - 11:56 pmDSM-MOB
7h 53m1 stop
American Airlines Logo
5:08 am - 10:40 amMOB-DSM
5h 32m1 stop
$249American Airlines
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Thu, Oct 30 - Mon, Nov 3
American Airlines Logo
5:04 am - 10:16 amDSM-MOB
5h 12m1 stop
American Airlines Logo
5:30 pm - 11:30 pmMOB-DSM
6h 00m1 stop
$259American Airlines
Find Deal
Thu, Nov 13 - Thu, Nov 20
United Airlines Logo
5:45 am - 2:22 pmDSM-MOB
8h 37m2 stops
United Airlines Logo
9:05 am - 8:45 pmMOB-DSM
11h 40m2 stops
$288United Airlines
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Mon, Nov 3 - Fri, Nov 7
Multiple Airlines Logo
3:40 pm - 8:38 pmDSM-MEM
28h 58m1 stop
Multiple Airlines Logo
12:23 pm - 10:40 pmMEM-DSM
10h 17m1 stop
$293Multiple Airlines
Find Deal
Fri, Jan 16 - Wed, Jan 21
Southwest Logo
6:25 am - 5:40 pmDSM-MEM
11h 15m2 stops
Southwest Logo
8:15 am - 7:20 pmMEM-DSM
11h 05m2 stops
$306Southwest
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Fri, Nov 14 - Sat, Nov 15
United Airlines Logo
2:52 pm - 9:31 pmDSM-BTR
6h 39m1 stop
United Airlines Logo
3:56 pm - 10:20 pmBTR-DSM
6h 24m1 stop
$312United Airlines
Find Deal
Sun, Nov 30 - Sun, Dec 7
Multiple Airlines Logo
12:51 pm - 8:21 pmDSM-MEM
31h 30m1 stop
Multiple Airlines Logo
8:07 pm - 7:03 pmMEM-DSM
22h 56m1 stop
$326Multiple Airlines
Find Deal
Fri, Nov 7 - Sat, Nov 8
Southwest Logo
8:00 am - 9:55 pmDSM-MEM
13h 55m2 stops
Southwest Logo
10:40 am - 8:25 pmMEM-DSM
9h 45m1 stop
$340Southwest
Find Deal
Booking Insights

KAYAK's insights & trends for Des Moines to Mississippi flights

Get data-powered insights and trends into flights from Des Moines to Mississippi to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to Mississippi?

The average price of all round-trip flights from Des Moines to Mississippi clicked on KAYAK for each day over the last 12 months.

When flying from Des Moines to Mississippi, you should consider leaving on a Saturday and avoid Wednesdays if you are looking for the best rates. For your return to Des Moines, you’ll find the best rates on Saturdays and the most expensive ones on Wednesdays.

Good to know

Low seasonAugust
Cheapest flight$107
Best time to beat the crowds with an average 40% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Des Moines to Memphis

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from Des Moines to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Mississippi?

    The cheapest time of day to fly to Mississippi is generally in the evening, when round-trip flights cost $296 on average. Morning departures are around 27% more expensive than evening flights, on average. The most expensive time of day to fly to Mississippi is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $560.

Reviews of the top airline flying from Des Moines to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11043 reviews
8.0Crew
7.5Boarding
6.9Entertainment
6.4Food
7.2Comfort
Airline reviews

A couple ladies from the crew were so rude and nasty. Thought they were mad at having to be there especially if you asked a question. This will make me think twice next time if I book a flight with you.

6.0 GoodJean, Oct 2025TUS - DFW
Read more American Airlines reviews

A couple ladies from the crew were so rude and nasty. Thought they were mad at having to be there especially if you asked a question. This will make me think twice next time if I book a flight with you.

Delays to take off and to leave the plane after landing added a lot of time to this flight.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Always seated jammed in rear of aircraft Admirals Club food at DFW terminal D was absolute worst food experience and I pay $600/year to eat this dried out junk

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

It was a typical flight. We had a delay which seems to be the normality now. And we had no in flight service due to conditions.

Flight attendants on this flight were very attentive and friendly

After we landed we sat on the tarmac for 1.5 hours waiting to get to our gate. Ridiculous.

the trip to madrid was uncomfortable with my legs touching the seat in front of me

Everything you need to know for your flight from Des Moines to Mississippi

Information on your arrival and departure airports

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