$72 Find Cheap Flights from Iowa to Missouri

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1 adult, Economy, 0 bags

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Good to know

Low seasonJanuary
Cheapest flight$72
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly with an average 1% increase in price.
Flight from Des Moines to St. Louis

FAQs for booking flights from Iowa to Missouri

  • How does KAYAK find such low prices on flights from Iowa to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Iowa to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Iowa to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Iowa to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Iowa to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Iowa to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Iowa to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Iowa to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many airports are there in Missouri?

    There are 8 airports in Missouri. The busiest airport is St. Louis Lambert Airport (STL), with 49% of all flights arriving there.

  • Which is the cheapest airport to fly into in Missouri?

    Prices will differ depending on the departure airport, but generally, the cheapest airport to fly to in Missouri is Lambert-St Louis Airport (STL), with an average flight price of $256.

  • What is the cheapest day to fly to Missouri?

    Based on KAYAK data, the cheapest day to fly to Missouri is Wednesday where round-trip tickets can be as cheap as $361. On the other hand, the most expensive day to fly is Sunday, where round-trip prices are $418 on average.

  • What is the cheapest time of day to fly to Missouri?

    The cheapest time of day to fly to Missouri is generally in the evening, when round-trip flights cost $385 on average. Morning departures are around 5% more expensive than evening flights, on average. The most expensive time of day to fly to Missouri is generally in the morning, which is peak travel time and where the average cost of a ticket is $405.

  • What is the cheapest flight to Missouri?

    The cheapest ticket to Missouri from Iowa found in the last 72 hours was to St. Louis, at $104 round-trip. The most popular route is Burlington (BRL) to St. Louis (STL) and the cheapest round-trip airline ticket found on this route in the last 72 hours was $104.

  • How many cities have direct flights to Missouri?

    From Iowa, there are direct flights to Missouri from 1 city. This city is Des Moines and there are 23 direct flights each week.

  • How many direct flights to Missouri are there each day?

    There are around 4 direct flights from within Iowa to Missouri every day. Most flights (35%) depart in the afternoon.

  • How many direct flights to Missouri are there each week?

    Each week there are around 23 direct flights from within Iowa to Missouri. The most common day for departures is Friday, with 26% of flights taking off on this day.

  • How long is the flight to Missouri?

    An average nonstop flight from Iowa to Missouri takes 4h 27m, covering a distance of 280 miles. The shortest route is Des Moines (DSM) to St. Louis (STL) with an average flight time of 1h 10m.

  • How many long-haul flights are there to Missouri each week?

    There are not any long-haul (6-12 hour flight duration) or medium-haul (3-6 hour flight duration) flights to Missouri. Instead, there are 23 short-haul flights (up to 3 hour flight duration), with the most arriving from Des Moines.

  • What are the most popular destinations in Missouri?

    Based on KAYAK flight searches, the most popular destination is St. Louis (62% of total searches to Missouri). The next most popular destination is Kansas City (38%).

Reviews of the top 4 airlines serving from Iowa to Missouri

 
Need help choosing which airline to fly with from Iowa to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4248 reviews
8.0Comfort
7.5Entertainment
7.0Food
8.1Boarding
8.6Crew
Airline reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

2.0 MediocreMatthew, Jan 2026
DAL - SAN
Read more Southwest reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Pretty seamless, just a tad bit late in taking off and landing.

Flight was fine other than there was a gate change that I was not notified of. By chance I happened to check my phone and saw the change, otherwise, we would have missed our connecting flight.

Haven’t flown on SW in years. Flight was on time departing and arriving. Served vegan butter onion flavored pretzels which were bad. Coke served was in a tiny paper cup. Crew was not engaging. Felt like they were going through the motions. Old plane, tight seats and no leg room.

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Flight was on time. Wi-fi was a little spotty/slow. Boarding and exit were efficient.

Okay, not wonderful. Short flight. Wi-fi didn't work properly. Stuck waiting for a gate to open upon arrival for 20 or so minutes.

They sent a notice that they were boarding an hour early. We had to leave the club and run to the gate. They said sorry, that came from corporate and was a mistake. They did not have enough seating because the flight before it had not taken off on time. They moved our gate and delayed it for an hour.

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

Check-in, boarding and the flight from Phoenix to Houston was quick and easy. The flight from Houston to Shreveport was delayed 5 hours. It was frustrating but I think United handled it the best they could.

They lost my luggage, so, not happy. The crew was nice but my suitcases never made it, still trying to find out what happened!

The staff was hospitable and professional. The seat had a bit of wear. The winner shade was stuck 1/4 open. I received the best of both worlds. The morning sun was able to come in and blind the screen i was trying to use while at the same time it was too low to look out and enjoy the view. Rather embarrassing for a 1st class ticket.

Perfect flight. Smooth flight. Arrived 20 minutes early at destination. Excellent service.

The flights were on time which was great give. It was holiday travel season and there’d been some weather issues. The only complaint and this is every time with United is the terrible seat design. The head rest is not built for comfort and having my neck bent forward for a cross country trip reminded me while I try not to take United flights as a rule.

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

The flight was delayed by two de-icings. The seatbelt did not work correctly. It did not stay tight.

Everything was absolutely wonderful from check in to baggage claim. Staff was very professional and sweet. Will definitely recommend United to family and friends.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Hotter than Hades in August. Why, why do crews think that in the winter when we are already dressed for cold weather we need a cabin that is 82 degrees. Even the vents were blowing hot air.

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

The flight was on time and arrived early. The crew were friendly and helpful.

My carry on baggage was damaged. Entire trip, I had to carry the baggage. When complained to the boarding crew, they got mad at me and still asked me to valet check in the cabin baggage. Rude boarding crew!!!

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

Nothing to write home about, average flight experience. Seats were spacious enough, crew friendly enough. Loved the AA entertainment/wifi service.

Kayak was among the missing. There was not the usual advice regarding next gate after arriving in Dallas. No communication after the reminder to check in before the Moline flight. What happened?

They should have allowed for extra time to de-ice the plane before boarding passengers. This delayed us about 10-15 mins after we boarded. Overall experience was fine. Crew was friendly and on top of everything. We didn’t have any issues during the flight.

Experience was good. We were delayed in leaving by 15 mins because the flight was waiting on a family that was late in getting to the gate. Food and drink options were as expected. I highly recommend checking in ahead of time using the airline’s app so that it’s quicker to get your luggage tags as soon as you arrive at the terminal. No more waiting in long lines!

Overall experience was great. Flights were almost on time in departing and we arrived at our destination as scheduled. No issues with amenities or flight crew. Everything went well as as expected. Will fly again with American Airlines in the future!

We never made it due to delays on both ends. Gate attendant said it was mechanical but the system said otherwise, so no compensation. That’s not right.

Both were great flights with wonderful pilots! It was not fancy, very simple. But boarding was super easy and the flight was smooth. Pick up in DFW was at corporate terminal which was the only confusing part for uber but if you call the uber driver and drop a pin they come right to it.

Totally great experience. Would definitely travel with them again. Thanks.

Both my fights got cancelled. Said mechanical issues but on flight tracker the flights came in and left! We were lied to!!

Was very impressed they called to confirm he would be on the flight. Great customer service!

We had a wonderful flight due to the care of our experienced pilot and copilot and the magnificent air views from our comfortable seats. What excitement to be in such a small plane with such magnificent around us.

Multiple time changes, then we left earlier than we were told.

Communication could be better but the staff and crew were over the top friendly and helpful, The flight itself was smooth.

flight was cancelled literally at 10pm the night before an early morning flight with hardly any time to reschedule. Will never book with kayak again.

My flight was cancelled 12 hours before takeoff. I was not able to reschedule another flight to make connections and had to cancel the entire trip. The ticket that was supposed to replace the cancelled flight had no boarding pass and I was unable to get one at the airport so I was denied access to the rescheduled flight. I was refunded but I missed my daughter's birthday.

I had a family emergency and couldn’t make the flight, and they wouldn’t let me cancel/refund it (a *month* ahead of time), were especially difficult with me on the phone, and wouldn’t let me even so much as reschedule the flight or get credit.

Everything you need to know for your flight to Missouri

Cabin class types available on flights to Iowa

Cabin classes available on flights to Iowa. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.