$68 Find Cheap Flights from Iowa to Missouri

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Good to know

Low seasonJanuary
Cheapest flight$68
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly with an average 4% increase in price.
Flight from Des Moines to St. Louis

FAQs for booking flights from Iowa to Missouri

  • How does KAYAK find such low prices on flights from Iowa to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Iowa to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Iowa to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Iowa to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Iowa to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Iowa to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Iowa to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Iowa to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many airports are there in Missouri?

    There are 8 airports in Missouri. The busiest airport is St. Louis Lambert Airport (STL), with 47% of all flights arriving there.

  • Which is the cheapest airport to fly into in Missouri?

    Prices will differ depending on the departure airport, but generally, the cheapest airport to fly to in Missouri is Lambert-St Louis Airport (STL), with an average flight price of $233.

  • What is the cheapest day to fly to Missouri?

    Based on KAYAK data, the cheapest day to fly to Missouri is Tuesday where round-trip tickets can be as cheap as $375. On the other hand, the most expensive day to fly is Saturday, where round-trip prices are $427 on average.

  • What is the cheapest time of day to fly to Missouri?

    The cheapest time of day to fly to Missouri is generally in the evening, when round-trip flights cost $394 on average. Morning departures are around 5% more expensive than evening flights, on average. The most expensive time of day to fly to Missouri is generally in the morning, which is peak travel time and where the average cost of a ticket is $413.

  • What is the cheapest flight to Missouri?

    The cheapest ticket to Missouri from Iowa found in the last 72 hours was to St. Louis, at $104 round-trip. The most popular route is Burlington (BRL) to St. Louis (STL) and the cheapest round-trip airline ticket found on this route in the last 72 hours was $104.

  • What is the cheapest month to fly from Iowa to Missouri?

    The cheapest month for flights from Iowa to Missouri is September, when tickets cost $182 (return) on average. On the other hand, the most expensive months are November and July, when the average cost of round-trip tickets is $643 and $570 respectively.

  • How many cities have direct flights to Missouri?

    From Iowa, there are direct flights to Missouri from 1 city. This city is Des Moines and there are 17 direct flights each week.

  • How many direct flights to Missouri are there each day?

    There are around 3 direct flights from within Iowa to Missouri every day. Most flights (53%) depart at night.

  • How many direct flights to Missouri are there each week?

    Each week there are around 17 direct flights from within Iowa to Missouri. The most common day for departures is Monday, with 24% of flights taking off on this day.

  • How long is the flight to Missouri?

    An average nonstop flight from Iowa to Missouri takes 4h 14m, covering a distance of 280 miles. The shortest route is Des Moines (DSM) to St. Louis (STL) with an average flight time of 1h 05m.

  • How many long-haul flights are there to Missouri each week?

    There are not any long-haul (6-12 hour flight duration) or medium-haul (3-6 hour flight duration) flights to Missouri. Instead, there are 17 short-haul flights (up to 3 hour flight duration), with the most arriving from Des Moines.

  • What are the most popular destinations in Missouri?

    Based on KAYAK flight searches, the most popular destination is St. Louis (64% of total searches to Missouri). The next most popular destination is Kansas City (36%).

Reviews of the top 4 airlines serving from Iowa to Missouri

 
Need help choosing which airline to fly with from Iowa to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4252 reviews
7.0Food
8.1Boarding
8.0Comfort
8.6Crew
7.5Entertainment
Airline reviews

No delays and arrived to destination 30 min early. Staff was super friendly.

10.0 ExcellentIlevba, Nov 2025DCA - DAL
Read more Southwest reviews

No delays and arrived to destination 30 min early. Staff was super friendly.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

It was rough. The staff was unprofessional, the choice of on board drinks terrible, it was cramped in space at every airport, they always ran out of overhead bin space so they pressured people to check bags for free or we couldn’t leave on the plane— so I did check my bag to help, and they nearly lost my bag. My bag did not arrive on the luggage belt, another man on my flight and I had to waste our time going to the baggage office to search for our bags. I would only fly southwest again if it was my last choice. Also, my flights were consistently delayed over and over again— at one point they straight up told us we were waiting for the pilot to arrive.

Crew could have been friendlier, maybe I'm spoiled by SW crews. In flight wifi was good. Would be nice to have more food offerings on a 4 plus hour flight

Had to get off plane from prior flight even though I had to reboard same plane to continue to my final destination.

Everything a cheap airline should be at normal airline rates.

Plane crashed into a bus or some other vehicle on the ground while pulling out of the gate. No injuries, but wing tip was damaged and returned to gate for “maintenance issues” and we departed 5 hours later because the plane went out of service and new plane was flown in from a nearby airport, Midway.

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Full cans of soda would be nice. A choice between two snacks would be appreciated.

Tried watching free movie and it kept freezing so I couldn’t finish.

Very thoughtful flight attendant offered me water immediately since I had run to make my connection.

Door to door, the crew and staff were amazing. It was a stressful travel day with delays, but they were focused on customers and doing what they could to get us to our destinations.

Even though we were delayed, we were able to make our connection

Starlink wifi on the Embraer E175 is an excellent experience. I was able to connect and work from IAD all the way to approach into BTV.

Older aircraft, no meal, only food was for purchase. Not impressed United.

United needs to step up their game. Delayed flight leaving Seattle, San Francisco. Older aircraft, not very comfortable.

Always wish for more healthy, gluten free options. We have to bring our own.

Having a long layover, I was very appreciative of the ability to stand by for an earlier flight. Other airlines like Delta have refused this to me in the past, just to be mean (because my ticket class wasn't high enough). United went out of their way to help me get to my destination early, which I really appreciated given that it was the third leg of a 24+ hour journey for me.

Other than a way way too cold cabinets for the entire flight, all was great

One bag is incorrect and not acceptable for an international flight. The food was not just good. I won't fly with them again.

The flight was delayed multiple times, again no fault of American but again the extra cost, for everything makes it feel like a cheap airline! Especially when flights are outrageously expensive already

Horrible. Both legs of my flight were delayed more than 6 hours. No compensation, no screens on the plane, and the plane was not clean.

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

We were told the flight was delayed 5 times, then it was moved to the next day.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Totally great experience. Would definitely travel with them again. Thanks.

Both my fights got cancelled. Said mechanical issues but on flight tracker the flights came in and left! We were lied to!!

Was very impressed they called to confirm he would be on the flight. Great customer service!

We had a wonderful flight due to the care of our experienced pilot and copilot and the magnificent air views from our comfortable seats. What excitement to be in such a small plane with such magnificent around us.

Multiple time changes, then we left earlier than we were told.

Communication could be better but the staff and crew were over the top friendly and helpful, The flight itself was smooth.

flight was cancelled literally at 10pm the night before an early morning flight with hardly any time to reschedule. Will never book with kayak again.

My flight was cancelled 12 hours before takeoff. I was not able to reschedule another flight to make connections and had to cancel the entire trip. The ticket that was supposed to replace the cancelled flight had no boarding pass and I was unable to get one at the airport so I was denied access to the rescheduled flight. I was refunded but I missed my daughter's birthday.

I had a family emergency and couldn’t make the flight, and they wouldn’t let me cancel/refund it (a *month* ahead of time), were especially difficult with me on the phone, and wouldn’t let me even so much as reschedule the flight or get credit.

Flight was cancelled, communication was poor and should have canceled flight much earlier.

Everything you need to know for your flight to Missouri

Cabin class types available on flights to Iowa

Cabin classes available on flights to Iowa. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.