DSM - STL

$49 Find Cheap Flights from Des Moines to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to St. Louis departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to St. Louis, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Des Moines to St. Louis (DSM-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to St. Louis

Tue, Aug 12 - Thu, Aug 14
Southwest Logo
8:25 am - 9:30 amDSM-STL
1h 05mnonstop
Southwest Logo
9:40 pm - 10:50 pmSTL-DSM
1h 10mnonstop
$97Southwest
Find Deal
Tue, Aug 12 - Thu, Aug 14
Southwest Logo
8:25 am - 9:30 amDSM-STL
1h 05mnonstop
Southwest Logo
9:40 pm - 10:50 pmSTL-DSM
1h 10mnonstop
$124Southwest
Find Deal
Tue, Aug 12 - Thu, Aug 14
Delta Logo
5:25 pm - 11:22 pmDSM-STL
5h 57m1 stop
Delta Logo
5:11 pm - 10:39 pmSTL-DSM
5h 28m1 stop
$167Delta
Find Deal
Wed, Aug 13 - Thu, Aug 14
Delta Logo
6:00 am - 2:41 pmDSM-STL
8h 41m2 stops
Delta Logo
6:00 am - 10:16 amSTL-DSM
4h 16m1 stop
$172Delta
Find Deal
Mon, Aug 11 - Wed, Aug 13
American Airlines Logo
3:20 pm - 8:18 pmDSM-STL
4h 58m1 stop
American Airlines Logo
8:40 am - 4:48 pmSTL-DSM
8h 08m1 stop
$220American Airlines
Find Deal
Wed, Aug 13 - Sat, Aug 16
United Airlines Logo
6:50 pm - 10:45 pmDSM-STL
3h 55m1 stop
United Airlines Logo
4:45 pm - 11:59 pmSTL-DSM
7h 14m1 stop
$223United Airlines
Find Deal
Thu, Aug 14 - Sat, Aug 16
American Airlines Logo
7:32 am - 1:12 pmDSM-STL
5h 40m1 stop
American Airlines Logo
4:32 pm - 11:45 pmSTL-DSM
7h 13m1 stop
$224American Airlines
Find Deal
Sat, Aug 9 - Wed, Aug 13
United Airlines Logo
6:50 pm - 10:45 pmDSM-STL
3h 55m1 stop
United Airlines Logo
8:00 am - 2:41 pmSTL-DSM
6h 41m1 stop
$255United Airlines
Find Deal
Thu, Jul 24 - Sun, Jul 27
 Logo
6:32 pm - 6:41 pmDSM-STL
24h 09m2 stops
 Logo
10:47 am - 6:06 pmSTL-DSM
31h 19m2 stops
Wed, Jul 23 - Wed, Jul 30
 Logo
11:00 am - 9:52 amDSM-STL
22h 52m3 stops
 Logo
11:24 am - 10:38 pmSTL-DSM
35h 14m2 stops
Useful Info

KAYAK's insights & trends for Des Moines to St. Louis flights

Get data-powered insights and trends into flights from Des Moines to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to St. Louis?

The average price of all round-trip flights from Des Moines to St. Louis clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to St. Louis on a Tuesday, as we generally find the cheapest rates on that day for this route. On the other hand, Saturday is the most expensive day to fly from Des Moines to St. Louis. For your return ticket, we recommend flying on a Saturday and avoiding Thursdays for the best deals.

What is the cheapest month to fly from Des Moines to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to St. Louis is August, where tickets cost $258 (return) on average. On the other hand, the most expensive months are September and February, where the average cost of round-trip tickets is $482 and $393 respectively.

Can I save money by flying with a layover from Des Moines to St. Louis?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $564, prices are generally cheapest when you fly direct.

Good to know

Low seasonJuly
High seasonNovember
Cheapest flight$49
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Des Moines to St. Louis

When to book flights from Des Moines to St. Louis

Are your dates flexible? Find out the best times to travel from Des Moines to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to St. Louis

  • What is the cheapest flight from Des Moines to St. Louis?

    In the last 3 days, the lowest price for a flight from Des Moines to St. Louis was $49 for a one-way ticket and $97 for a round-trip.

  • Do I need a passport to fly between Des Moines and St. Louis?

    No

  • Which airports will I be using when flying from Des Moines to St. Louis?

    When flying out of Des Moines you will be using Des Moines. You will be landing at St. Louis, also known as Lambert-St Louis.

  • Which airlines offer Wi-Fi service onboard planes from Des Moines to St. Louis?

    Delta, and American Airlines offer inflight Wi-Fi service on the Des Moines to St. Louis flight route.

  • Which aircraft models fly most regularly from Des Moines to St. Louis?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Des Moines to St. Louis flight route.

  • On which days can I fly direct from Des Moines to St. Louis?

    There are nonstop flights from Des Moines to St. Louis on a daily basis.

  • Which is the best airline for flights from Des Moines to St. Louis, Southwest or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to St. Louis are Southwest and United Airlines. With an average price for the route of $310 and an overall rating of 8.0, Southwest is the most popular choice. United Airlines is also a great choice for the route, with an average price of $379 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Des Moines to St. Louis

  • Looking for a cheap flight? 25% of our users found flights on this route for $173 or less one-way and $317 or less round-trip.

Prefer to fly direct from Des Moines to St. Louis?

Find which airlines fly direct from Des Moines Airport to Lambert-St Louis Airport, which days they fly and book direct flights.

Direct departures

Des Moines to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Lambert-St Louis to Des Moines

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights
See more direct flights

Top airlines flying from Des Moines to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4287 reviews
8.2Boarding
7.1Food
8.6Crew
8.0Comfort
7.6Entertainment
Airline reviews

Southwest is typically delayed, and it gets wearisome. It is no longer a discount airline and you get way less than you pay for when it comes to comfort and Ce.

6.0 GoodDavid, Jun 2025BWI - COS
Read more Southwest reviews

Southwest is typically delayed, and it gets wearisome. It is no longer a discount airline and you get way less than you pay for when it comes to comfort and Ce.

We sat on the plane on the tarmac for 4 hours.

I'm not a fan of Southwest's model. I don't like the herding style of boarding.

Flight crew and cabin crew were great. I had to rearrange flights because my original flight was 3hrs delayed for weather, the rub is the flight I moved to boarded on time then we sat at the gate for 2 hours because scheduling stole our first officer for another flight, TWICE. Then our actual FO was an hour delayed. To make it worse my original flight went from a 3 hour delay to departing 15min EARLY. Just poor scheduling operations all around.

Bring back peanuts Take our drink orders when were all seated, especially after you switch to assigned seating.

Staff was far less than helpful at all times. Departure and arrival times mean nothing to Southwest. Extremely disappointed, will never fly with them again, and I’ll be sure to share my experience with all.

It is southwest seat was ok. Not the most comfortable seat

I’ve always loved Southwest. No issues at all. I was flying standby and the gate agent was extremely friendly and helpful. Boarding was smooth and I was able to get a window seat in the emergency exit row. Crew was fantastic! They were very professional and accommodating. We had to divert from our destination due to weather but the flight crew kept everyone at ease and informed us of all pertinent information. Excellent flight

The price of the tickets isn't matching the flight experience. No matter how long the flight is, you're only getting pretzels. The flight attendants looked unkept and over it.

Plz don't take away free bags and free seating

it was so bad. I tried to board my flight from vancouver to saskatoon. And to my surprise they did not board me cause the flight was changed and no email was send to me. and on my boarding pass which i got from seattle says different flight. I did not knew anyone from Vancouver, air canada crew was rude, i asked for today flight but they were rude and i had early morning dental appointment in saskatoon. I was so much in pain and my whole day is wasted today. and i suffered alot. They did provide me hotel but they did not provide me any food. I am really really disappointed first time had so bad experience with air canada. I may think twice to book it again. If i can get any reply or any composition that would be great. Thanks

It was fine, definitely older planes with no charging or anything. There’s no entertainment set up on board, but it is nice that they allow you to access the in flight entertainment from your phone without having to pay for the Wi-Fi and they do offer free texting.

Boarding was mayhem. Late boarding by 15 minutes because of lack of staff (missing 1 flight attendant. We had to wait for an arrival of another plane before we could board). Flight was a little rough, but cannot blame on airlines.

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Very comfortable (upgraded to business class). The audio on my screen didn’t work, but I managed to play the audio through my phone while watching the screen.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

I was supposed to be on business class at first class from Denver back to Miami due to weather changes. I missed my connection and it’s put on a flight to Fort Lauderdale. Instead of honoring my business class/1st class ticket, they put me in coach, but there were two first class seats open. I think it’s absolutely disgusting that I paid for first class $1300 ticket and they put me in economy and they had to open seats available and I have still not been refunded the difference. I ended up having to eat a snack box instead of the meal I was supposed to get and did not get home till 2 AM so I think that’s a little pathetic that I had to live off crackers for dinner And my poor dog ate some cheese and salami. Oh yes, apparently when they switched me to the new flight they forgot to mention I had a service dog

Excellent service despite turbulence during the flight. Flight attendants were remarkable!

I liked that the flight was nonstop from ORD to CIU for $200 round trip.

Smooth flight, especially take off and landing, and great crew on board. Really loved the stroopwaffles!

Everything you need to know for your flight from Des Moines to St. Louis

Information on your arrival and departure airports

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