Which airports can I use when flying from Des Moines to St. Louis?

Flights from Des Moines to St. Louis usually depart from Des Moines (DSM) and arrive at Lambert-St Louis (STL).

What cabin classes can I book on flights from Des Moines to St. Louis?

Only Economy Class is available on flights from Des Moines to St. Louis.

How much can I save by taking a layover when flying from Des Moines to St. Louis?

On this route, nonstop and layover fares are close on average, with nonstop at $310 round-trip and layover options via Minneapolis St Paul (MSP) at $315.

Which aircraft model is used most often on flights from Des Moines to St. Louis?

The Airbus A319 family is used most often on this route, operated mainly by United Airlines and Allegiant Air. Other aircraft seen on the route include Airbus A320-100/200 variants.

Which airports do connecting flights from Des Moines to St. Louis pass through?

One-stop flights from Des Moines to St. Louis most commonly connect through: • Chicago O'Hare Intl (ORD) - 55% of one-stop connections • Minneapolis St Paul (MSP) - 32% of one-stop connections • Chicago Midway (MDW) - 13% of one-stop connections

Can I save money by using flexible dates for flights from Des Moines to St. Louis?

Yes. Flexible dates can save you up to 52% on flights from Des Moines to St. Louis. Tuesday is the cheapest departure day at $204 round-trip on average, while Thursday is the most expensive at $419, a difference of $215. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

What popular places can I visit in St. Louis?

Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

How long is a flight from Des Moines to St. Louis?

There are currently no nonstop flights available from Des Moines to St. Louis. Flights with 1 layover take between 3h 43m and 4h 45m in total, depending on the connection.

Do I need a passport to fly from Des Moines to St. Louis?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Des Moines to St. Louis changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $220 to $1,789. That means the highest observed fare was about 8x higher than the lowest one.

How are flight prices from Des Moines to St. Louis looking right now?

One-way fares from Des Moines to St. Louis are currently lower than usual. Average one-way flight prices are about $182, which is 13% below the typical average for this route.

How much time can I save by choosing a different layover airport from Des Moines to St. Louis?

Flying via Minneapolis St Paul (MSP) gives the shortest average 1-stop total travel time at 3h 43m, compared with 4h 09m via Chicago O'Hare Intl (ORD) and 4h 45m via Chicago Midway (MDW).

What car rental options are available at Lambert-St Louis Airport (STL)?

Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates averaging $78 for economy cars. Top options include: • Hertz • Budget • Alamo • Enterprise Rent-A-Car • Payless

How much should I expect to pay for a Des Moines to St. Louis flight?

Round-trip flights from Des Moines to St. Louis range from $281 to $398, with an average of $314 over the past 12 months. Anything below $281 counts as a good deal.

How much is a round-trip flight from Des Moines to St. Louis?

Round-trip flights from Des Moines to St. Louis typically range from $281 to $398. The lowest price found in the past 5 days was $220, on Frontier.

Which airline is the cheapest to fly from Des Moines to St. Louis?

Frontier ($220) and American Airlines ($237) are the cheapest airlines to fly round-trip from Des Moines to St. Louis according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Des Moines to St. Louis?

Chicago O'Hare Intl (ORD) is the most popular layover for the Des Moines to St. Louis route. 55% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ORD.

What is the cheapest layover airport when flying from Des Moines to St. Louis?

Flights via Minneapolis St Paul (MSP) offer the most affordable fares, with an average round-trip price of $315. Based on KAYAK data over the past 3 months.

When flying from Des Moines to St. Louis which airport offers the shortest layover?

Minneapolis St Paul (MSP) had the shortest average connection time for Des Moines to St. Louis layovers at 2h 16m over the past 3 months.

$119 CHEAP FLIGHTS from Des Moines to St. Louis (DSM - STL)

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Cheapest round-trip

$220

Typical prices: $281-$398

Frontier

Mon 11/26Sun 12/2

DSM - STL • 1 stop

Cheapest one-way

$119

Typical prices: $159-$279

Southwest

Sat 11/24

DSM - STL • 1 stop

When to travel

December

Cheapest • 16% price drop

March

Most popular

Good to know

Top layover airports

Minneapolis St Paul (MSP)

Cheapest • Avg $315 (round-trip)

Chicago O'Hare Intl (ORD)

Shortest trip • 4h 09m (one-way)

Insights

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Flight Deals

Cheap Flights from Des Moines to St. Louis (DSM-STL)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Des Moines to St. Louis

Thu, Nov 26 - Wed, Dec 2

8:28 pm - 11:03 amDSM Des Moines-STL Lambert-St Louis

14h 35m1 stop Denver Intl

7:58 pm - 7:40 pmSTL Lambert-St Louis-DSM Des Moines

23h 42m1 stop Denver Intl

$220Frontier

Thu, Dec 3 - Wed, Dec 9

8:35 pm - 10:57 amDSM Des Moines-STL Lambert-St Louis

14h 22m1 stop Denver Intl

7:54 pm - 7:42 pmSTL Lambert-St Louis-DSM Des Moines

23h 48m1 stop Denver Intl

$234Frontier

Thu, Nov 26 - Thu, Dec 3

9:31 am - 4:34 pmDSM Des Moines-STL Lambert-St Louis

7h 03m1 stop Chicago O'Hare Intl

5:02 am - 8:53 amSTL Lambert-St Louis-DSM Des Moines

3h 51m1 stop Chicago O'Hare Intl

$237American Airlines

Thu, Nov 26 - Wed, Dec 2

2:48 pm - 7:31 pmDSM Des Moines-STL Lambert-St Louis

4h 43m1 stop Minneapolis St Paul

6:03 am - 10:21 amSTL Lambert-St Louis-DSM Des Moines

4h 18m1 stop Minneapolis St Paul

$237Delta

Thu, Nov 26 - Thu, Dec 3

1:30 pm - 4:55 pmDSM Des Moines-STL Lambert-St Louis

3h 25m1 stop Chicago Midway

2:20 pm - 10:05 pmSTL Lambert-St Louis-DSM Des Moines

7h 45m2 stops Atlanta Hartsfield-Jackson Chicago Midway

$242Southwest

Fri, Jan 8 - Sat, Jan 9

8:00 am - 12:13 pmDSM Des Moines-STL Lambert-St Louis

4h 13m1 stop Chicago O'Hare Intl

6:45 pm - 11:14 pmSTL Lambert-St Louis-DSM Des Moines

4h 29m1 stop Chicago O'Hare Intl

$287United Airlines

Fri, Nov 20 - Sun, Nov 22

8:00 am - 12:10 pmDSM Des Moines-STL Lambert-St Louis

4h 10m1 stop Chicago O'Hare Intl

6:50 pm - 10:59 pmSTL Lambert-St Louis-DSM Des Moines

4h 09m1 stop Chicago O'Hare Intl

$302United Airlines

Mon, Nov 23 - Sat, Nov 28

11:00 am - 4:31 pmDSM Des Moines-STL Lambert-St Louis

5h 31m1 stop Minneapolis St Paul

9:45 am - 2:08 pmSTL Lambert-St Louis-DSM Des Moines

4h 23m1 stop Minneapolis St Paul

$308Delta

Sat, Nov 14 - Sat, Nov 21

7:23 pm - 11:59 pmDSM Des Moines-STL Lambert-St Louis

4h 36m1 stop Chicago O'Hare Intl

8:12 pm - 12:19 amSTL Lambert-St Louis-DSM Des Moines

4h 07m1 stop Chicago O'Hare Intl

$326American Airlines

Tue, Nov 17 - Thu, Nov 19

1:58 pm - 6:17 pmDSM Des Moines-STL Lambert-St Louis

4h 19m1 stop Chicago O'Hare Intl

5:00 am - 9:01 amSTL Lambert-St Louis-DSM Des Moines

4h 01m1 stop Chicago O'Hare Intl

$326American Airlines

Booking Insights

Price, demand and travel trends for Des Moines to St. Louis flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Des Moines to St. Louis? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to St. Louis departing in november.

Find deals

Low season	June
High season	March
Cheapest flight	$119

Beat the crowds with an average 55% drop in travelers.

The most popular month to fly with an average 44% increase in travelers.

One-way flight from Des Moines to St. Louis

When to book flights from Des Moines to St. Louis

Are your dates flexible? Find out the best times to travel from Des Moines to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Des Moines to St. Louis?
Only Economy Class is available on flights from Des Moines to St. Louis.
How long is a flight from Des Moines to St. Louis?
There are currently no nonstop flights available from Des Moines to St. Louis. Flights with 1 layover take between 3h 43m and 4h 45m in total, depending on the connection.
Do I need a passport to fly from Des Moines to St. Louis?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Des Moines to St. Louis flight?
Round-trip flights from Des Moines to St. Louis range from $281 to $398, with an average of $314 over the past 12 months. Anything below $281 counts as a good deal.
How much can I save by taking a layover when flying from Des Moines to St. Louis?
On this route, nonstop and layover fares are close on average, with nonstop at $310 round-trip and layover options via Minneapolis St Paul (MSP) at $315.
Which aircraft model is used most often on flights from Des Moines to St. Louis?
The Airbus A319 family is used most often on this route, operated mainly by United Airlines and Allegiant Air. Other aircraft seen on the route include Airbus A320-100/200 variants.
Have flight prices from Des Moines to St. Louis changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $220 to $1,789. That means the highest observed fare was about 8x higher than the lowest one.
How are flight prices from Des Moines to St. Louis looking right now?
One-way fares from Des Moines to St. Louis are currently lower than usual. Average one-way flight prices are about $182, which is 13% below the typical average for this route.
What car rental options are available at Lambert-St Louis Airport (STL)?
Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates averaging $78 for economy cars. Top options include:

• Hertz
• Budget
• Alamo
• Enterprise Rent-A-Car
• Payless
Which airports can I use when flying from Des Moines to St. Louis?
Flights from Des Moines to St. Louis usually depart from Des Moines (DSM) and arrive at Lambert-St Louis (STL).
Which airports do connecting flights from Des Moines to St. Louis pass through?
One-stop flights from Des Moines to St. Louis most commonly connect through:

• Chicago O'Hare Intl (ORD) - 55% of one-stop connections
• Minneapolis St Paul (MSP) - 32% of one-stop connections
• Chicago Midway (MDW) - 13% of one-stop connections
Can I save money by using flexible dates for flights from Des Moines to St. Louis?
Yes. Flexible dates can save you up to 52% on flights from Des Moines to St. Louis. Tuesday is the cheapest departure day at $204 round-trip on average, while Thursday is the most expensive at $419, a difference of $215.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Des Moines to St. Louis?
Flying via Minneapolis St Paul (MSP) gives the shortest average 1-stop total travel time at 3h 43m, compared with 4h 09m via Chicago O'Hare Intl (ORD) and 4h 45m via Chicago Midway (MDW).
What popular places can I visit in St. Louis?
Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

If your dates are flexible, aim for a Tuesday departure and avoid flying on Thursday. On this route, Tuesday flights average $204, about $215 less than Thursday fares (51% savings) based on the last 12 months.
If you can choose when to travel, plan your Des Moines to St. Louis trip for December. Fares historically average $264 round-trip in that month - typically $371 less than the most expensive month, which is February (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Lambert-St Louis Airport.

• Renaissance St. Louis Airport Hotel
• Drury Inn & Suites St. Louis Airport
• DoubleTree by Hilton St. Louis Airport

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DSM - STL

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Everything you should know

Cheap Flights from Des Moines to St. Louis (DSM-STL)

Recent round-trip flight deals from Des Moines to St. Louis

Recent one-way flight deals from Des Moines to St. Louis

Recent last minute flight deals from Des Moines to St. Louis

Price, demand and travel trends for Des Moines to St. Louis flights

How much is a round-trip flight from Des Moines to St. Louis?

Which airline is the cheapest to fly from Des Moines to St. Louis?

What’s the most popular layover airport when flying from Des Moines to St. Louis?

What is the cheapest layover airport when flying from Des Moines to St. Louis?

When flying from Des Moines to St. Louis which airport offers the shortest layover?

Key details for Des Moines to St. Louis flights

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When to book flights from Des Moines to St. Louis

Your Des Moines to St. Louis flight questions, answered

Your guide to booking Des Moines to St. Louis flights

More options for your flight from Des Moines to St. Louis

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