Find Deals on Flights from Islip Long Island to Buffalo (ISP - BUF)

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
Students
under 26
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Islip Long Island to Buffalo

(Round-trip)
Depart: Thu Jan 5 2017 Return: Tue Jan 10 2017 Trip spans 6 days
American Airlines
American Airlines
ISP
6:50a
BUF
10:11a
3h 21m
1 stop
BUF
8:06a
ISP
12:15p
4h 09m
1 stop
Depart: Wed Jan 4 2017 Return: Mon Jan 9 2017 Trip spans 6 days
Southwest
Southwest
ISP
2:35a
BUF
7:00a
4h 25m
1 stop
BUF
3:20a
ISP
6:35a
3h 15m
1 stop
Depart: Mon May 1 2017 Return: Tue May 2 2017 Trip spans 2 days
Southwest
Southwest
ISP
1:40p
BUF
6:30p
4h 50m
1 stop
BUF
1:25p
ISP
4:35p
3h 10m
1 stop
Depart: Tue Dec 20 2016 Return: Wed Jan 4 2017 Trip spans 16 days
American Airlines
American Airlines
ISP
2:05a
BUF
5:44a
3h 39m
1 stop
BUF
1:55a
ISP
6:22a
4h 27m
1 stop
Depart: Tue May 2 2017 Return: Wed May 3 2017 Trip spans 2 days
Southwest
Southwest
ISP
1:40p
BUF
6:30p
4h 50m
1 stop
BUF
8:20a
ISP
11:25a
3h 05m
1 stop
Depart: Wed Dec 21 2016 Return: Wed Dec 28 2016 Trip spans 8 days
American Airlines
American Airlines
ISP
2:05a
BUF
5:44a
3h 39m
1 stop
BUF
1:55a
ISP
6:22a
4h 27m
1 stop
Depart: Wed May 3 2017 Return: Thu May 4 2017 Trip spans 2 days
Southwest
Southwest
ISP
1:40p
BUF
6:30p
4h 50m
1 stop
BUF
3:35a
ISP
7:40a
4h 05m
1 stop
Depart: Thu Dec 29 2016 Return: Sat Dec 31 2016 Trip spans 3 days
American Airlines
American Airlines
ISP
2:05a
BUF
5:44a
3h 39m
1 stop
BUF
6:10a
ISP
9:53a
3h 43m
1 stop
Depart: Fri Jan 6 2017 Return: Wed Jan 11 2017 Trip spans 6 days
American Airlines
American Airlines
ISP
6:50a
BUF
10:11a
3h 21m
1 stop
BUF
3:15a
ISP
7:25a
4h 10m
1 stop
Depart: Sun Jan 1 2017 Return: Wed Jan 4 2017 Trip spans 4 days
Southwest
Southwest
ISP
12:40a
BUF
5:30a
4h 50m
1 stop
BUF
1:00a
ISP
6:00a
5h 00m
1 stop
Depart: Sat Dec 17 2016 Return: Mon Dec 19 2016 Trip spans 3 days
American Airlines
American Airlines
ISP
6:50a
BUF
10:11a
3h 21m
1 stop
BUF
6:10a
ISP
9:53a
3h 43m
1 stop
Depart: Tue Feb 21 2017 Return: Thu Feb 23 2017 Trip spans 3 days
Southwest
Southwest
ISP
3:45a
BUF
8:30a
4h 45m
1 stop
BUF
3:20a
ISP
6:35a
3h 15m
1 stop
Depart: Sun Jan 8 2017 Return: Tue Jan 10 2017 Trip spans 3 days
American Airlines
American Airlines
ISP
2:05a
BUF
5:44a
3h 39m
1 stop
BUF
8:06a
ISP
12:15p
4h 09m
1 stop
Depart: Sun Dec 11 2016 Return: Tue Dec 13 2016 Trip spans 3 days
American Airlines
American Airlines
ISP
1:15p
BUF
5:11p
3h 56m
1 stop
BUF
1:55a
ISP
6:22a
4h 27m
1 stop
Depart: Thu Apr 13 2017 Return: Sat Apr 15 2017 Trip spans 3 days
Southwest
Southwest
ISP
7:50a
BUF
12:25p
4h 35m
1 stop
BUF
1:15p
ISP
6:45p
5h 30m
1 stop
Depart: Thu Dec 22 2016 Return: Thu Dec 29 2016 Trip spans 8 days
American Airlines
American Airlines
ISP
6:50a
BUF
10:11a
3h 21m
1 stop
BUF
1:55a
ISP
6:22a
4h 27m
1 stop
Depart: Sat Dec 24 2016 Return: Wed Jan 4 2017 Trip spans 12 days
American Airlines
American Airlines
ISP
2:45a
BUF
7:44a
4h 59m
1 stop
BUF
6:10a
ISP
9:53a
3h 43m
1 stop
Depart: Sun Dec 25 2016 Return: Sat Dec 31 2016 Trip spans 7 days
American Airlines
American Airlines
ISP
2:05a
BUF
6:33a
4h 28m
1 stop
BUF
8:20a
ISP
2:00p
5h 40m
1 stop
Depart: Sat Feb 18 2017 Return: Sun Feb 19 2017 Trip spans 2 days
Southwest
Southwest
ISP
1:25a
BUF
6:45a
5h 20m
1 stop
BUF
1:05p
ISP
6:35p
5h 30m
1 stop
Depart: Mon Dec 26 2016 Return: Fri Jan 6 2017 Trip spans 12 days
American Airlines
American Airlines
ISP
2:05a
BUF
5:44a
3h 39m
1 stop
BUF
6:10a
ISP
9:53a
3h 43m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Islip
$286
Destination

Buffalo
$286