ISP - GSP

$271 Find Cheap Flights from Islip to Greenville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Islip to Greenville departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Greenville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Islip to Greenville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Islip to Greenville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$345
Southwest
Fri 2/6Tue 2/10
ISP - GSP • 1 stop
Cheapest one-way
$271
Southwest
Sat 2/14
ISP - GSP • 1 stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Greenville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Islip to Greenville (ISP-GSP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Islip to Greenville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Islip to Greenville

Fri, Feb 6 - Tue, Feb 10
Southwest Logo
5:55 am - 10:10 am
ISP
-
GSP
4h 15m
1 stop
Southwest Logo
6:15 pm - 9:55 pm
GSP
-
ISP
3h 40m
1 stop
$345Southwest
Fri, Jan 30 - Mon, Feb 2
Southwest Logo
6:00 am - 10:40 am
ISP
-
GSP
4h 40m
1 stop
Southwest Logo
10:05 am - 4:15 pm
GSP
-
ISP
6h 10m
1 stop
$346Southwest
Fri, Feb 6 - Tue, Feb 10
Southwest Logo
5:55 am - 6:00 pm
ISP
-
GSP
12h 05m
2 stops
Southwest Logo
10:05 am - 4:15 pm
GSP
-
ISP
6h 10m
1 stop
$350Southwest
Fri, Jan 30 - Mon, Feb 2
Southwest Logo
6:00 am - 10:40 am
ISP
-
GSP
4h 40m
1 stop
Southwest Logo
11:15 am - 9:55 pm
GSP
-
ISP
10h 40m
2 stops
$351Southwest
Fri, Feb 6 - Tue, Feb 10
Southwest Logo
5:55 am - 6:00 pm
ISP
-
GSP
12h 05m
2 stops
Southwest Logo
11:15 am - 9:55 pm
GSP
-
ISP
10h 40m
2 stops
$356Southwest
Fri, Feb 6 - Sun, Feb 8
Southwest Logo
5:55 am - 10:10 am
ISP
-
GSP
4h 15m
1 stop
Southwest Logo
10:05 am - 4:15 pm
GSP
-
ISP
6h 10m
1 stop
$387Southwest
Fri, Feb 6 - Sun, Feb 8
Southwest Logo
5:55 am - 6:00 pm
ISP
-
GSP
12h 05m
2 stops
Southwest Logo
10:05 am - 4:15 pm
GSP
-
ISP
6h 10m
1 stop
$392Southwest
Fri, Jan 30 - Mon, Feb 2
Southwest Logo
6:00 am - 5:35 pm
ISP
-
GSP
11h 35m
2 stops
Southwest Logo
11:15 am - 9:55 pm
GSP
-
ISP
10h 40m
2 stops
$397Southwest
Fri, Feb 6 - Sun, Feb 8
Southwest Logo
5:55 am - 6:00 pm
ISP
-
GSP
12h 05m
2 stops
Southwest Logo
11:15 am - 9:55 pm
GSP
-
ISP
10h 40m
2 stops
$408Southwest
Wed, Feb 18 - Sun, Feb 22
Multiple Airlines Logo
7:35 pm - 9:07 pm
ISP
-
GSP
25h 32m
1 stop
Multiple Airlines Logo
5:17 pm - 7:38 am
GSP
-
ISP
14h 21m
2 stops
$468Multiple Airlines
Booking Insights

KAYAK's insights & trends for Islip to Greenville flights

Get data-powered insights and trends into flights from Islip to Greenville to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Islip and Greenville?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Islip to Greenville.

There is just one airline that flies from Islip to Greenville direct and that is Southwest. The best round-trip deal found from Southwest for the route is $218.

Good to know

Low seasonApril
Cheapest flight$271
Best time to beat the crowds with an average 46% drop in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Islip to Greenville

When to book flights from Islip to Greenville

Are your dates flexible? Find out the best times to travel from Islip to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Islip to Greenville

  • What is the cheapest flight from Islip to Greenville?

    In the last 3 days, the lowest price for a flight from Islip to Greenville was $271 for a one-way ticket and $345 for a round-trip.

  • Do I need a passport to fly between Islip and Greenville?

    No

  • Which airports will I be using when flying from Islip to Greenville?

    When flying out of Islip you will be using Islip Long Island. You will be landing at Greenville, also known as Greenville.

  • Which aircraft models fly most regularly from Islip to Greenville?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Islip to Greenville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Islip to Greenville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Islip to Greenville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Greenville from Islip is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Islip to Greenville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Greenville with an airline and back to Islip with another airline. Booking your flights between Islip and GSP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Islip to Greenville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Greenville from Islip up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Islip to Greenville

 
See real verified KAYAK customer reviews for airlines flying from Islip to Greenville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Islip to Greenville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4257 reviews
7.5Entertainment
8.1Boarding
8.6Crew
8.0Comfort
7.0Food
Airline reviews

3 hour delay. Had to change plans and was still delayed.

2.0 MediocreAnonymous, Jan 2026
SFO - SAN
Read more Southwest reviews

3 hour delay. Had to change plans and was still delayed.

The staff was very friendly, professional, and courteous. The overall flight was a great experience.

The crew canceled the complementary snack and drink in anticipation of turbulence that never materialized. I was counting on the drink (water) to take the the doses of medication - prescribed for my heart condition - that were due during the flight. Since no snack or meal was served on this flight, I cannot rate the food quality. Otherwise, this flight was excellent.

Departure was delayed more than 1/2 hour while we waited for luggage (only) transfer from another flight/plane. Once approved for takeoff, the flight was excellent.

We got exit row seats both flights. Everything was running on time

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Pretty seamless, just a tad bit late in taking off and landing.

Flight was fine other than there was a gate change that I was not notified of. By chance I happened to check my phone and saw the change, otherwise, we would have missed our connecting flight.

Haven’t flown on SW in years. Flight was on time departing and arriving. Served vegan butter onion flavored pretzels which were bad. Coke served was in a tiny paper cup. Crew was not engaging. Felt like they were going through the motions. Old plane, tight seats and no leg room.

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Everything you need to know for your flight from Islip to Greenville

Information on your arrival and departure airports