ISP - GSP

$159 Find Cheap Flights from Islip to Greenville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Islip to Greenville departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Greenville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Islip to Greenville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Islip to Greenville, as well as popular online travel agencies
Travelers love KAYAK
41’299’237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$252
Southwest
Wed 4/22Wed 4/29
ISP - GSP • 1 stop
Cheapest one-way
$159
Southwest
Sat 4/18
ISP - GSP • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Islip and Greenville. You'll need at least 1 connection.
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We hope you love your trip to Greenville!
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Booking Insights
Flight Deals

Cheap Flights from Islip to Greenville (ISP-GSP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Islip to Greenville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Islip to Greenville

Wed, Apr 22 - Wed, Apr 29
Southwest Logo
9:00 am - 1:10 pm
ISP
-
GSP
4h 10m
1 stop
Southwest Logo
8:20 am - 1:50 pm
GSP
-
ISP
5h 30m
1 stop
$252Southwest
Wed, Apr 22 - Wed, Apr 29
Southwest Logo
9:00 am - 1:10 pm
ISP
-
GSP
4h 10m
1 stop
Southwest Logo
12:50 pm - 10:10 pm
GSP
-
ISP
9h 20m
2 stops
$258Southwest
Wed, Apr 22 - Wed, Apr 29
Southwest Logo
12:30 pm - 9:40 pm
ISP
-
GSP
9h 10m
2 stops
Southwest Logo
12:50 pm - 10:10 pm
GSP
-
ISP
9h 20m
2 stops
$263Southwest
Wed, Apr 22 - Fri, Apr 24
Southwest Logo
6:30 am - 1:10 pm
ISP
-
GSP
6h 40m
1 stop
Southwest Logo
1:50 pm - 8:25 pm
GSP
-
ISP
6h 35m
1 stop
$303Southwest
Wed, Apr 22 - Fri, Apr 24
Southwest Logo
12:30 pm - 9:40 pm
ISP
-
GSP
9h 10m
2 stops
Southwest Logo
1:50 pm - 8:25 pm
GSP
-
ISP
6h 35m
1 stop
$308Southwest
Mon, Jun 1 - Sat, Jun 6
Southwest Logo
4:30 pm - 10:35 pm
ISP
-
GSP
6h 05m
2 stops
Southwest Logo
8:15 am - 10:55 pm
GSP
-
ISP
14h 40m
2 stops
$319Southwest
Wed, Apr 22 - Fri, Apr 24
Southwest Logo
12:30 pm - 9:40 pm
ISP
-
GSP
9h 10m
2 stops
Southwest Logo
6:25 am - 4:30 pm
GSP
-
ISP
10h 05m
2 stops
$330Southwest
Thu, Apr 9 - Mon, Apr 13
Multiple Airlines Logo
5:30 am - 1:12 pm
ISP
-
GSP
7h 42m
1 stop
Multiple Airlines Logo
8:18 pm - 11:10 am
GSP
-
ISP
38h 52m
2 stops
$371Multiple Airlines
Tue, Jun 2 - Fri, Jun 5
Southwest Logo
6:30 am - 1:10 pm
ISP
-
GSP
6h 40m
1 stop
Southwest Logo
1:55 pm - 5:15 pm
GSP
-
ISP
3h 20m
1 stop
$382Southwest
Wed, Jul 15 - Sat, Jul 18
Southwest Logo
2:55 pm - 8:15 pm
ISP
-
GSP
5h 20m
1 stop
Southwest Logo
8:15 am - 2:50 pm
GSP
-
ISP
6h 35m
1 stop
$387Southwest
Booking Insights

Good to know

Low seasonAugust
Cheapest flight$159
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly and prices are also 13% lower on average.
Flight from Islip to Greenville

When to book flights from Islip to Greenville

Are your dates flexible? Find out the best times to travel from Islip to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Islip to Greenville

  • What is the cheapest flight from Islip to Greenville?

    In the last 3 days, the lowest price for a flight from Islip to Greenville was $159 for a one-way ticket and $252 for a round-trip.

  • Do I need a passport to fly between Islip and Greenville?

    No

  • Which airports will I be using when flying from Islip to Greenville?

    When flying out of Islip you will be using Islip Long Island. You will be landing at Greenville, also known as Greenville.

  • Which aircraft models fly most regularly from Islip to Greenville?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Islip to Greenville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Islip to Greenville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Islip to Greenville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Greenville from Islip is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Islip to Greenville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Greenville with an airline and back to Islip with another airline. Booking your flights between Islip and GSP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Islip to Greenville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Greenville from Islip up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Islip to Greenville

 
See real verified KAYAK customer reviews for airlines flying from Islip to Greenville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Islip to Greenville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4331 reviews
7.5Entertainment
7.0Food
8.1Boarding
8.0Comfort
8.6Crew
Airline reviews

Southwest continues to do less for more money. Flight attendants used to be fun and friendly. But now it’s like they don’t even see you. Such a shame.

6.0 GoodDavid, Mar 2026
RSW - BWI
Read more Southwest reviews

Southwest continues to do less for more money. Flight attendants used to be fun and friendly. But now it’s like they don’t even see you. Such a shame.

Great flight. Good snacks and drinks. Grateful it was free. The flight from Nashville to louisville, i think her name was Tracy (not sure that's right) super awesome, nice and cheerful. She really enjoyed being at work today! She was the person who scanned the boarding pass on flight wn941. She should be recommended for a raise !

I liked it better when you were truer to your roots Am paying more for less fun

Southwest was greaat! The most expensive but the least upsetting for those we were flying to see.

I flew twice this week on Southwest, was delayed over 2 hours both ways. From Pittsburgh to Chicago it was due to weather but the gate agents, pilot etc were great at updating everyone. Today from Midway to Pittsburgh the plane had come from an international location, kept getting delayed, no information was given until we were delayed for the third time. It was ridiculous, whoever scheduled that plane to fly to Pittsburgh after didn’t consider a lot of things.

Boarding was easy. The seats are small and fairly uncomfortable

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

We had a 5 hour delay on the tarmac in Baltimore

Long layover between flights to Long Island from BWI - need better coordination between flights

I elected to pay for the upgrades and found very little difference

Everything you need to know for your flight from Islip to Greenville

Information on your arrival and departure airports