ISP - TYS

$194 Find Cheap Flights from Islip to Knoxville - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Islip to Knoxville departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Islip to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Islip to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$303
Southwest
Fri 9/11Mon 9/14
ISP - TYS • 1 stop
Cheapest one-way
$194
Southwest
Sun 7/12
ISP - TYS • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Islip and Knoxville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Baltimore (BWI)
Cheapest • Avg $450 (round-trip)
Washington, D.C. (IAD)
Shortest trip • 4h 23m (one-way)
Insights
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Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Islip to Knoxville (ISP-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Islip to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Islip to Knoxville

Fri, Sep 11 - Mon, Sep 14
Southwest Logo
4:05 pm - 7:55 pm
ISP
-
TYS
3h 50m
1 stop
Southwest Logo
8:25 am - 12:35 pm
TYS
-
ISP
4h 10m
1 stop
$303Southwest
Fri, Sep 11 - Mon, Sep 14
Southwest Logo
4:05 pm - 7:55 pm
ISP
-
TYS
3h 50m
1 stop
Southwest Logo
8:25 am - 9:30 pm
TYS
-
ISP
13h 05m
2 stops
$314Southwest
Wed, Jul 22 - Sat, Jul 25
Southwest Logo
2:55 pm - 9:20 pm
ISP
-
TYS
6h 25m
1 stop
Southwest Logo
8:00 am - 11:35 am
TYS
-
ISP
3h 35m
1 stop
$318Southwest
Wed, Jul 22 - Sat, Jul 25
Southwest Logo
4:40 pm - 9:20 pm
ISP
-
TYS
4h 40m
1 stop
Southwest Logo
1:35 pm - 11:15 pm
TYS
-
ISP
9h 40m
2 stops
$323Southwest
Wed, Jul 22 - Sat, Jul 25
Southwest Logo
6:00 am - 5:00 pm
ISP
-
TYS
11h 00m
2 stops
Southwest Logo
1:35 pm - 11:15 pm
TYS
-
ISP
9h 40m
2 stops
$328Southwest
Fri, Sep 11 - Mon, Sep 14
Southwest Logo
10:20 am - 6:35 pm
ISP
-
TYS
8h 15m
2 stops
Southwest Logo
8:25 am - 9:30 pm
TYS
-
ISP
13h 05m
2 stops
$335Southwest
Mon, Sep 28 - Fri, Oct 2
Southwest Logo
4:05 pm - 7:55 pm
ISP
-
TYS
3h 50m
1 stop
Southwest Logo
8:15 am - 12:00 pm
TYS
-
ISP
3h 45m
1 stop
$336Southwest
Mon, Sep 28 - Fri, Oct 2
Southwest Logo
6:10 am - 5:10 pm
ISP
-
TYS
11h 00m
2 stops
Southwest Logo
8:15 am - 12:00 pm
TYS
-
ISP
3h 45m
1 stop
$341Southwest
Mon, Sep 28 - Fri, Oct 2
Southwest Logo
6:10 am - 5:10 pm
ISP
-
TYS
11h 00m
2 stops
Southwest Logo
8:15 am - 10:00 pm
TYS
-
ISP
13h 45m
2 stops
$352Southwest
Fri, Aug 7 - Wed, Aug 12
Southwest Logo
4:05 pm - 7:55 pm
ISP
-
TYS
3h 50m
1 stop
Southwest Logo
8:05 am - 4:55 pm
TYS
-
ISP
8h 50m
1 stop
$362Southwest
Booking Insights

KAYAK's insights & trends for Islip to Knoxville flights

Get data-powered insights and trends into flights from Islip to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What is the most popular layover airport when flying from Islip to Knoxville?

Percentage of 1-stop round-trip flights from Islip to Knoxville chosen by KAYAK users via each layover airport in the last 12 months (only includes trips with the same layover airport on both legs).

Baltimore (BWI) is the top choice – 91% of KAYAK users who clicked on 1-stop flights from Islip to Knoxville picked an itinerary connecting there.

What is the cheapest layover airport when flying from Islip to Knoxville?

Average round-trip price for 1-stop flights from Islip to Knoxville clicked by KAYAK users in the last 12 months (only includes trips with the same layover airport on both legs).

Flights via Baltimore (BWI) offer the most affordable fares, with an average round-trip price of $450.

Which layover airport offers the shortest total travel time from Islip to Knoxville?

Shortest average total travel time for 1-stop one-way flights from Islip to Knoxville via different layover airports, based on KAYAK user data from the last 12 months.

Consider flying via Washington, D.C. (IAD) for the shortest journey. The average one-way travel time for flights connecting there is 4h 23m.

Which layover airport has the quickest connection when flying from Islip to Knoxville?

Average layover duration at different layover airports for 1-stop one-way flights from Islip to Knoxville, based on KAYAK user data from the last 12 months.

If you prefer a quick connection, Washington, D.C. (IAD) often has the shortest layovers from Islip to Knoxville, with an average of 1h 15m.

Find deals

Good to know

Cheapest flight$194
Flight from Islip to Knoxville

When to book flights from Islip to Knoxville

Are your dates flexible? Find out the best times to travel from Islip to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Islip to Knoxville

  • What is the cheapest flight from Islip to Knoxville?

    In the last 5 days, the lowest price for a flight from Islip to Knoxville was $194 for a one-way ticket and $303 for a round-trip.

  • Do I need a passport to fly between Islip and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Islip to Knoxville?

    Islip and Knoxville are both served by 1 main airport. You will leave Islip from Islip Long Island and will be arriving at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Islip to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Islip to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Islip to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Islip to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Islip is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Islip to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Islip with another airline. Booking your flights between Islip and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Islip to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Islip up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Islip to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Islip to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Islip to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4235 reviews
7.0Food
8.0Comfort
8.1Boarding
7.5Entertainment
8.6Crew
Airline reviews

Flight was delayed over 3 hours. Planes were dirty. Staff indifferent. And they serve vegan pretzels as snacks.

2.0 MediocreMatthew, Jun 2026
CVG - MDW
Read more Southwest reviews

Flight was delayed over 3 hours. Planes were dirty. Staff indifferent. And they serve vegan pretzels as snacks.

It was great. The gate staff were very helpful in Portland when my son forgot his rolling bag and had to go back to get it just in time to make it on the plane. We really appreciate that. Great job!

Airline is not very senior friendly. Flights are late, forcing us to run to the connecting flight. Food is awful. Wish they would go back to pretzels and peanuts. During flight, pressurization isn’t quite right and all of our ears get plugged. Everything is nickel and dime, charging for boarding, seat selection and legroom. While a screen at the desk in the gate area says check your roll on bag now for free due to space limitation, the employee at the desk will not check the bag without a $100 fee. Insane.

Kayak could’ve posted the correct gate number. Almost missed my flight.

Slow boarding, limited food and drink portions. Bad delays and turbulence

there were two flight attendants that were up front...that were the best! They get KUDOs for making my trip only fantastic. Tell them Jeff said that!

OKay. I sat in the back of the plane and it was really loud between babies and little kids, and adults who.like to talk a lot and loudly most of the flight.

Flight coming out of Buffalo was delayed, so we had to be rescheduled on another flight from Baltimore to Phoenix which means we had a long layover and got home 3.5 hours late. Shuttle to parking stopped at 10pm, so we had to pay for an Uber to the parking lot and got charged an extra day of parking since it was after midnight. Not the best experience. Long day!

Was fine, delayed and feels like southwest is always late

I don't know why flying out of Sarasota requires two plane changes.

Everything you need to know for your flight from Islip to Knoxville

Information on your arrival and departure airports

Islip (ISP)
Knoxville (TYS)