ISP - TYS

$325 Find Cheap Flights from Islip to Knoxville - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$390
Typical prices: $332-$531
Southwest
Mon 11/26Mon 12/3
ISP - TYS • 1 stop
Nonstop flights
There are currently no direct flights between Islip and Knoxville. You'll need to take a connecting flight to reach the destination.
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Cheap Flights from Islip to Knoxville (ISP-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Islip to Knoxville

Thu, Nov 26 - Thu, Dec 3
Southwest Logo
5:45 am - 12:30 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
6h 45m1 stop Baltimore/Washington
Southwest Logo
7:55 am - 4:15 pmTYS  Knoxville McGhee Tyson-ISP Islip Long Island
8h 20m1 stop Baltimore/Washington
$390Southwest
Thu, Nov 26 - Thu, Dec 3
Southwest Logo
5:45 am - 3:25 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
9h 40m2 stops Baltimore/Washington Nashville Intl
Southwest Logo
7:55 am - 4:15 pmTYS  Knoxville McGhee Tyson-ISP Islip Long Island
8h 20m1 stop Baltimore/Washington
$396Southwest
Tue, Apr 20 - Sat, Apr 24
Southwest Logo
4:10 pm - 8:10 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
4h 00m1 stop Baltimore/Washington
Southwest Logo
7:55 am - 11:55 amTYS  Knoxville McGhee Tyson-ISP Islip Long Island
4h 00m1 stop Baltimore/Washington
$427Southwest
Tue, Apr 20 - Sat, Apr 24
Southwest Logo
5:45 am - 4:45 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
11h 00m2 stops Baltimore/Washington Orlando
Southwest Logo
7:55 am - 11:55 amTYS  Knoxville McGhee Tyson-ISP Islip Long Island
4h 00m1 stop Baltimore/Washington
$432Southwest
Tue, Apr 20 - Sat, Apr 24
Southwest Logo
5:45 am - 4:45 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
11h 00m2 stops Baltimore/Washington Orlando
Southwest Logo
12:55 pm - 11:00 pmTYS  Knoxville McGhee Tyson-ISP Islip Long Island
10h 05m2 stops Tampa Baltimore/Washington
$437Southwest
Mon, Apr 19 - Sat, Apr 24
Southwest Logo
4:45 pm - 9:25 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
4h 40m1 stop Baltimore/Washington
Southwest Logo
7:55 am - 11:55 amTYS  Knoxville McGhee Tyson-ISP Islip Long Island
4h 00m1 stop Baltimore/Washington
$447Southwest
Tue, Mar 16 - Fri, Mar 19
Southwest Logo
5:20 pm - 9:50 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
4h 30m1 stop Baltimore/Washington
Southwest Logo
12:40 pm - 10:00 pmTYS  Knoxville McGhee Tyson-ISP Islip Long Island
9h 20m1 stop Orlando
$452Southwest
Mon, Apr 19 - Sat, Apr 24
Southwest Logo
4:45 pm - 9:25 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
4h 40m1 stop Baltimore/Washington
Southwest Logo
12:55 pm - 11:00 pmTYS  Knoxville McGhee Tyson-ISP Islip Long Island
10h 05m2 stops Tampa Baltimore/Washington
$452Southwest
Mon, Nov 16 - Mon, Nov 23
Multiple Airlines Logo
11:13 am - 5:18 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
30h 05m2 stops Myrtle Beach Intl Fort Lauderdale
Multiple Airlines Logo
7:11 pm - 3:45 pmTYS  Knoxville McGhee Tyson-ISP Islip Long Island
20h 34m1 stop Orlando
$454Multiple Airlines
Wed, Nov 11 - Sun, Nov 15
Multiple Airlines Logo
12:00 pm - 7:43 pmISP  Islip Long Island-TYS Knoxville McGhee Tyson
31h 43m2 stops Raleigh-Durham Tampa
Multiple Airlines Logo
7:00 am - 5:31 pmTYS  Knoxville McGhee Tyson-ISP Islip Long Island
10h 31m1 stop Orlando Sanford Intl
$545Multiple Airlines
Booking Insights

Price, demand and travel trends for Islip to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Islip to Knoxville?

Round-trip flights from Islip to Knoxville typically range from $332 to $531. The lowest price found in the past 5 days was $390, on Southwest.

Key details for Islip to Knoxville flights

Cheapest flight

$390
Round-trip flight from Islip to Knoxville

When to book flights from Islip to Knoxville

Are your dates flexible? Find out the best times to travel from Islip to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Islip to Knoxville flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Islip to Knoxville?

    Only Economy Class is available on flights from Islip to Knoxville.

  • How long is a flight from Islip to Knoxville?

    A nonstop flight from Islip to Knoxville takes 00m, covering 682 miles.

  • Do I need a passport to fly from Islip to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Islip to Knoxville flight?

    Round-trip flights from Islip to Knoxville range from $332 to $531, with an average of $400 over the past 12 months. Anything below $332 counts as a good deal.

  • Have flight prices from Islip to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $390 to $864. That means the highest observed fare was about 2x higher than the lowest one.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $80 for economy cars. Top options include:

    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Thrifty
    • Avis

  • Which airports can I use when flying from Islip to Knoxville?

    Flights from Islip to Knoxville usually depart from Islip Long Island (ISP) and arrive at Knoxville McGhee Tyson (TYS).

  • Which airports do connecting flights from Islip to Knoxville pass through?

    Most connecting flights from Islip to Knoxville pass through Baltimore/Washington (BWI), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from Islip to Knoxville?

    Yes. Flexible dates can save you up to 56% on flights from Islip to Knoxville. Tuesday is the cheapest departure day at $294 round-trip on average, while Wednesday is the most expensive at $656, a difference of $362.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Your guide to booking Islip to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Wednesday. On this route, Tuesday flights average $294, about $362 less than Wednesday fares (55% savings) based on the last 12 months.

More options for your flight from Islip to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental