TYS - ISP

$179 Find Cheap Flights from Knoxville to Islip

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Islip departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Islip

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Islip, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Islip, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$300
Southwest
Wed 5/20Wed 5/27
TYS - ISP • 2 stops
Cheapest one-way
$108
Multiple Airlines
Fri 5/8
TYS - ISP • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Islip. You'll need at least 1 connection.
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Booking Insights
Flight Deals

Cheap Flights from Knoxville to Islip (TYS-ISP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Islip that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Islip

Wed, May 20 - Wed, May 27
Southwest Logo
12:50 pm - 10:10 pm
TYS
-
ISP
9h 20m
2 stops
Southwest Logo
4:10 pm - 8:50 pm
ISP
-
TYS
4h 40m
1 stop
$300Southwest
Wed, May 20 - Wed, May 27
Southwest Logo
12:50 pm - 10:10 pm
TYS
-
ISP
9h 20m
2 stops
Southwest Logo
6:30 am - 5:10 pm
ISP
-
TYS
10h 40m
2 stops
$305Southwest
Mon, May 18 - Mon, May 25
Multiple Airlines Logo
1:15 pm - 11:00 am
TYS
-
ISP
21h 45m
1 stop
Multiple Airlines Logo
11:00 am - 11:37 pm
ISP
-
TYS
12h 37m
1 stop
$323Multiple Airlines
Tue, May 26 - Sat, May 30
Multiple Airlines Logo
5:00 pm - 10:05 am
TYS
-
ISP
17h 05m
1 stop
Multiple Airlines Logo
6:43 pm - 12:26 pm
ISP
-
TYS
17h 43m
1 stop
$340Multiple Airlines
Tue, May 26 - Sat, May 30
Multiple Airlines Logo
5:00 pm - 1:33 pm
TYS
-
ISP
20h 33m
2 stops
Multiple Airlines Logo
6:43 pm - 6:37 pm
ISP
-
TYS
23h 54m
1 stop
$343Multiple Airlines
Mon, May 18 - Mon, May 25
Multiple Airlines Logo
1:15 pm - 11:00 am
TYS
-
ISP
21h 45m
1 stop
Multiple Airlines Logo
2:28 pm - 4:15 pm
ISP
-
TYS
25h 47m
2 stops
$365Multiple Airlines
Tue, May 26 - Sat, May 30
Southwest Logo
12:50 pm - 10:10 pm
TYS
-
ISP
9h 20m
2 stops
Southwest Logo
6:00 am - 6:30 pm
ISP
-
TYS
12h 30m
2 stops
$393Southwest
Wed, May 13 - Sun, May 17
Southwest Logo
8:15 am - 1:50 pm
TYS
-
ISP
5h 35m
1 stop
Southwest Logo
5:25 pm - 10:00 pm
ISP
-
TYS
4h 35m
1 stop
$437Southwest
Wed, May 13 - Sun, May 17
Southwest Logo
12:50 pm - 10:10 pm
TYS
-
ISP
9h 20m
2 stops
Southwest Logo
5:25 pm - 10:00 pm
ISP
-
TYS
4h 35m
1 stop
$442Southwest
Mon, May 18 - Mon, May 25
Southwest Logo
2:45 pm - 11:30 pm
TYS
-
ISP
8h 45m
2 stops
Southwest Logo
8:35 am - 6:10 pm
ISP
-
TYS
9h 35m
2 stops
$447Southwest
Booking Insights

Good to know

Cheapest flight$108
Flight from Knoxville to Islip

When to book flights from Knoxville to Islip

Are your dates flexible? Find out the best times to travel from Knoxville to Islip based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Islip

  • What is the cheapest flight from Knoxville to Islip?

    In the last 3 days, the lowest price for a flight from Knoxville to Islip was $179 for a one-way ticket and $300 for a round-trip.

  • Do I need a passport to fly between Knoxville and Islip?

    No

  • Which aircraft models fly most regularly from Knoxville to Islip?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Knoxville to Islip?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Islip.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Islip?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Islip from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Islip?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Islip with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and ISP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Islip?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Islip from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Islip

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Islip. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Islip? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4314 reviews
8.1Boarding
7.0Food
8.6Crew
7.5Entertainment
8.0Comfort
Airline reviews

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

10.0 Excellentlarry, Apr 2026
LGB - PHX
Read more Southwest reviews

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

no service at all due to turbulence. they should've at least given us snacks, there were only 10 people on the entire flight.

First time I've had to use the disabled accommodations. And I could not have had a better experience with Southwest, i was having trouble getting from one terminal to another due to my heart failure. And the next thing I know a Southwest agent had made sure. I had a wheelchair at all my flights. Can't thank them enough.

Delayed flight, lack of information, boarding process is a mess as is the carryon luggage causing issues when leaving the plane….just a poor experience.

Comfortable. Easy. No problems. Just wish they had gf options for snacks.

The crew was very kind and made going to Hawaii relaxing and fun to look forward to! Thank you Southwest for a pleasant flight!

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

We waited in the airplane for over 45 min for a southwest employee to make the flight. This cause over half the plane to miss their connecting flight in Denver. When we confronted the desk upon arrival, they told us the only flight they had was the next day leaving at 8:50 pm!!! Or they offered to get us to Burbank or LA, but after that we were on our own to get back to Santa Barbara. I paid for a flight from sba to bna bna to sba. My re entry into mom mode has been 💯 rough because of southwest mistake with my flight. And now I’m leaving to Reno tomorrow for a vballl tournament and just discovered that my leg in Vegas has me and my 3 kids on a stand by flight even though I had booked these ticket last year November!! Do better southwest!

Southwest is kind of a slum airline. It’s gotten more expensive over the years for less and less service. I am a Southwest Chase Visa card holder and was forced to choose a seat in the 26th row in the middle seat. However my wife who is a rewards member but doesn’t hold a card or anything else, gets randomly assigned a normally paid seat in row 6! How does that work?

For the first time in a long time, the Wi-Fi actually worked the entire flight! The flight crew was amazing as usual.

Everything you need to know for your flight from Knoxville to Islip

Information on your arrival and departure airports