$249 Find Cheap Flights from Ithaca to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Ithaca to South Carolina departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Ithaca to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Ithaca to South Carolina, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Ithaca to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$279
Myrtle Beach
Myrtle Beach2 stops$289
Greenville
Greenville1 stop$441
Columbia
Columbia1 stop$344
Charlotte
Charlotte1 stop$269
Charleston
Charleston1 stop$279
Myrtle Beach
Myrtle Beach2 stops$289
Greenville
Greenville1 stop$441
Columbia
Columbia1 stop$344
Charlotte
Charlotte1 stop$269

Book Cheap Ithaca to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Ithaca to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Ithaca to South Carolina

Wed, Apr 29 - Tue, May 5
Delta Logo
5:20 am - 10:14 am
ITH
-
CLT
4h 54m
1 stop
Delta Logo
6:00 am - 12:53 pm
CLT
-
ITH
6h 53m
1 stop
$269Delta
Wed, Apr 29 - Tue, May 5
Delta Logo
1:34 pm - 7:19 pm
ITH
-
CLT
5h 45m
1 stop
Delta Logo
2:30 pm - 11:46 pm
CLT
-
ITH
9h 16m
2 stops
$274Delta
Sat, Feb 28 - Wed, Mar 4
Delta Logo
5:29 am - 11:18 am
ITH
-
CHS
5h 49m
1 stop
Delta Logo
5:55 pm - 11:34 pm
CHS
-
ITH
5h 39m
1 stop
$279Delta
Wed, Apr 29 - Tue, May 5
Delta Logo
1:34 pm - 8:44 pm
ITH
-
CLT
7h 10m
2 stops
Delta Logo
12:49 pm - 11:46 pm
CLT
-
ITH
10h 57m
2 stops
$279Delta
Sat, Feb 28 - Wed, Mar 4
Delta Logo
3:03 pm - 10:04 pm
ITH
-
CHS
7h 01m
1 stop
Delta Logo
6:30 am - 2:23 pm
CHS
-
ITH
7h 53m
2 stops
$284Delta
Sat, Feb 28 - Wed, Mar 4
United Airlines Logo
6:00 am - 1:52 pm
ITH
-
CHS
7h 52m
2 stops
United Airlines Logo
10:20 am - 6:27 pm
CHS
-
ITH
8h 07m
2 stops
$289United Airlines
Sat, Apr 25 - Tue, Apr 28
United Airlines Logo
6:00 am - 2:17 pm
ITH
-
MYR
8h 17m
2 stops
United Airlines Logo
11:00 am - 11:59 pm
MYR
-
ITH
12h 59m
2 stops
$289United Airlines
Thu, Feb 26 - Mon, Mar 2
Delta Logo
3:03 pm - 10:30 pm
ITH
-
CLT
7h 27m
1 stop
Delta Logo
10:32 am - 2:23 pm
CLT
-
ITH
3h 51m
1 stop
$289Delta
Fri, Apr 17 - Mon, Apr 20
Delta Logo
1:34 pm - 11:53 pm
ITH
-
CLT
10h 19m
2 stops
Delta Logo
6:00 am - 12:53 pm
CLT
-
ITH
6h 53m
1 stop
$309Delta
Thu, Apr 16 - Mon, Apr 20
Delta Logo
5:20 am - 10:14 am
ITH
-
CLT
4h 54m
1 stop
Delta Logo
6:00 am - 12:53 pm
CLT
-
ITH
6h 53m
1 stop
$314Delta
Booking Insights

KAYAK's insights & trends for Ithaca to South Carolina flights

Get data-powered insights and trends into flights from Ithaca to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Ithaca to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Ithaca to South Carolina were found on Delta ($269) and United Airlines ($289).

Good to know

Cheapest flight$249
Flight from Ithaca to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Ithaca to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Ithaca to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Ithaca to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Ithaca to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Ithaca to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Ithaca to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Ithaca to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Ithaca to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Ithaca to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Ithaca to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Ithaca to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8203 reviews
8.1Boarding
7.9Comfort
7.2Food
7.8Entertainment
8.5Crew
Airline reviews

boarded at 5:30 pm, pushed away from gate at 6pm ... takeoff was not until ~6:45pm; disappointing

4.0 OkayLawrence, Feb 2026
LGA - JAX
Read more Delta reviews

boarded at 5:30 pm, pushed away from gate at 6pm ... takeoff was not until ~6:45pm; disappointing

Smooth boarding, pleasant and professional lady checking us in. Crew service was excellent, again pleasant, but professional. Nice touch-down on landing! Thank you Delta. 💗

Paid for wifi that didn't work. No plug in seat to work. No entertainment.

We departed early and made up time in the air allowing us to arrive 30 minutes early. Capt was incredibly genuine and thanked every passenger for flying with Delta. Completely humble and professional!

They double booked seats, the gate staff changed my ticket as I was boarding she went over to the computer and changed it without telling me. She messed up an entire three row section for me and others. Other travelers were outraged but the gate staff were so rude, so condescending saying it wasn't their problem to solve. I would rate this a zero if I could. Will not fly Delta again I'll stick with United and American.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

The entertainment screens were not working and there was no air condition the entire flight. Very uncomfortable.

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Very old flight - time to retire it for newer airplanes

2+ hours delayed Outlet in row 12 did not work Tv monitors did not work Lights kept off the entire flight for at 5pm-7pm flight

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Both of my flights arrived early and check in process was smooth

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Much better than Spirit. I was please by the easy fast check in and boarding

Everything you need to know for your flight from Ithaca to South Carolina

Information on your arrival and departure airports