$139 Find Cheap Flights from Ithaca to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Ithaca to South Carolina departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Ithaca to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Ithaca to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Ithaca to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$383
Myrtle Beach
Myrtle Beach2 stops$354
Greenville
Greenville1 stop$339
Columbia
Columbia2 stops$314
Charlotte
Charlotte1 stop$269
Charleston
Charleston1 stop$383
Myrtle Beach
Myrtle Beach2 stops$354
Greenville
Greenville1 stop$339
Columbia
Columbia2 stops$314
Charlotte
Charlotte1 stop$269

Book Cheap Ithaca to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Ithaca to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Ithaca to South Carolina

Thu, Apr 23 - Sun, Apr 26
Delta Logo
5:20 am - 10:14 am
ITH
-
CLT
4h 54m
1 stop
Delta Logo
6:00 am - 12:53 pm
CLT
-
ITH
6h 53m
1 stop
$269Delta
Thu, Mar 12 - Mon, Mar 16
United Airlines Logo
7:35 pm - 11:57 pm
ITH
-
CLT
4h 22m
1 stop
United Airlines Logo
7:40 pm - 11:42 pm
CLT
-
ITH
4h 02m
1 stop
$273United Airlines
Tue, Apr 21 - Fri, May 1
Delta Logo
5:20 am - 1:43 pm
ITH
-
CLT
8h 23m
2 stops
Delta Logo
6:00 am - 12:53 pm
CLT
-
ITH
6h 53m
1 stop
$274Delta
Sat, Apr 25 - Wed, Apr 29
Delta Logo
5:20 am - 1:43 pm
ITH
-
CLT
8h 23m
2 stops
Delta Logo
5:30 am - 12:53 pm
CLT
-
ITH
7h 23m
2 stops
$279Delta
Thu, Apr 23 - Thu, Apr 30
Delta Logo
5:20 am - 1:43 pm
ITH
-
CLT
8h 23m
2 stops
Delta Logo
6:00 am - 12:53 pm
CLT
-
ITH
6h 53m
1 stop
$309Delta
Thu, Mar 5 - Tue, Mar 10
Delta Logo
5:29 am - 2:21 pm
ITH
-
CAE
8h 52m
2 stops
Delta Logo
5:34 am - 12:53 pm
CAE
-
ITH
7h 19m
2 stops
$314Delta
Thu, Apr 23 - Tue, Apr 28
Delta Logo
5:20 am - 1:43 pm
ITH
-
CLT
8h 23m
2 stops
Delta Logo
5:30 am - 12:53 pm
CLT
-
ITH
7h 23m
2 stops
$314Delta
Tue, Feb 17 - Sat, Feb 21
Delta Logo
3:03 pm - 10:30 pm
ITH
-
CLT
7h 27m
1 stop
Delta Logo
6:00 am - 2:20 pm
CLT
-
ITH
8h 20m
2 stops
$329Delta
Fri, Apr 10 - Sun, Apr 26
Delta Logo
1:33 pm - 9:35 am
ITH
-
CLT
20h 02m
1 stop
Delta Logo
6:00 am - 12:53 pm
CLT
-
ITH
6h 53m
1 stop
$333Delta
Tue, Mar 3 - Mon, Mar 9
United Airlines Logo
7:45 pm - 11:44 pm
ITH
-
CAE
3h 59m
1 stop
United Airlines Logo
7:39 pm - 11:42 pm
CAE
-
ITH
4h 03m
1 stop
$339United Airlines
Booking Insights

KAYAK's insights & trends for Ithaca to South Carolina flights

Get data-powered insights and trends into flights from Ithaca to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Ithaca to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Ithaca to South Carolina were found on Delta ($269) and United Airlines ($339).

Good to know

Cheapest flight$139
Flight from Ithaca to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Ithaca to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Ithaca to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Ithaca to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Ithaca to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Ithaca to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Ithaca to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Ithaca to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Ithaca to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Ithaca to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Ithaca to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Ithaca to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8138 reviews
7.2Food
8.1Boarding
8.5Crew
7.9Comfort
7.8Entertainment
Airline reviews

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

10.0 ExcellentZebrina, Jan 2026
LGA - CAE
Read more Delta reviews

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

The entertainment screens were not working and there was no air condition the entire flight. Very uncomfortable.

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

I truly love flying with Delta. They have always treated me with the upmost respect

The flight was great. The gate location was way to far away!!!

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Not being stranded in Chicago for her airport to 11:30 tomorrow morning the 3rd

the whole trip was smooth, and as comfortable as flying is these days. flight crew was friendly and very courteous and helpful.

The attendant on board was amazing. She should be doing business/first international long haul.

I was fully checked in the prior night and i was unchecked and then didn’t have a seat when I boarded. Instead of an aisle seat, I was out in the middle seat of the very last row of the plane.

In overall it was a good experience, the only down point was that the entertainment screen was working properly.

HORRIBLE, my initial flight was cancelled, they made me pay $200 extra dollars and that got cancelled as well! After 6 cancellations I decided to get a refund because I needed to get home to my babies. Out of $1000+ dollars they offered me only $40 in refund! Totally unacceptable! The flight that they cancelled I was able to fly it on another airline. I had to spend $400 on one way tickets just to get home! I’m still getting the runaround.

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Seated dude next to me even though lots of empty rows. But main thing was we sat on the tarmac after landing for 30 minutes because of, in the words of the dude who sat next to me, “operational incompetence”. We got changing directions about where to pick up gate checked bags. Pilot and flight attendant were awesome though.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

Flight arrived 30 min early and bag was waiting at the baggage pickup. United Club HNL was one of the nicest in the system

Everything you need to know for your flight from Ithaca to South Carolina

Information on your arrival and departure airports