$284 Find Cheap Flights from Ithaca to South Carolina - Compare and Save
This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Ithaca to South Carolina departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
Cheap Flights from Ithaca to South Carolina
Cheapest round-trip prices found by our users on KAYAK in the last 5 daysBook Cheap Ithaca to South Carolina Plane Tickets
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Ithaca to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Cheap flights from Ithaca to South Carolina with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.
Thu, Jan 21 - Mon, Jan 25
5:55 am - 12:10 pmITH Ithaca Tompkins County-CHS Charleston
6h 15m1 stop New York John F Kennedy Intl
6:00 am - 1:15 pmCHS Charleston-ITH Ithaca Tompkins County
7h 15m1 stop New York John F Kennedy Intl
$339Delta
Tue, Jan 19 - Thu, Jan 28
2:00 pm - 8:42 pmITH Ithaca Tompkins County-CHS Charleston
6h 42m1 stop New York John F Kennedy Intl
5:25 pm - 11:21 pmCHS Charleston-ITH Ithaca Tompkins County
5h 56m1 stop New York John F Kennedy Intl
$339Delta
Mon, Jan 18 - Sat, Jan 30
5:55 am - 12:10 pmITH Ithaca Tompkins County-CHS Charleston
6h 15m1 stop New York John F Kennedy Intl
6:00 am - 1:15 pmCHS Charleston-ITH Ithaca Tompkins County
7h 15m1 stop New York John F Kennedy Intl
$339Delta
Sat, Jan 23 - Thu, Jan 28
5:55 am - 12:10 pmITH Ithaca Tompkins County-CHS Charleston
6h 15m1 stop New York John F Kennedy Intl
5:25 pm - 11:21 pmCHS Charleston-ITH Ithaca Tompkins County
5h 56m1 stop New York John F Kennedy Intl
$339Delta
Wed, Jan 20 - Thu, Jan 28
5:55 am - 12:10 pmITH Ithaca Tompkins County-CHS Charleston
6h 15m1 stop New York John F Kennedy Intl
5:25 pm - 11:21 pmCHS Charleston-ITH Ithaca Tompkins County
5h 56m1 stop New York John F Kennedy Intl
$339Delta
Tue, Jan 19 - Wed, Jan 27
5:55 am - 12:10 pmITH Ithaca Tompkins County-CHS Charleston
6h 15m1 stop New York John F Kennedy Intl
6:00 am - 1:15 pmCHS Charleston-ITH Ithaca Tompkins County
7h 15m1 stop New York John F Kennedy Intl
$339Delta
Thu, Jan 21 - Thu, Jan 28
5:55 am - 12:10 pmITH Ithaca Tompkins County-CHS Charleston
6h 15m1 stop New York John F Kennedy Intl
5:25 pm - 11:21 pmCHS Charleston-ITH Ithaca Tompkins County
5h 56m1 stop New York John F Kennedy Intl
$339Delta
Fri, Jan 22 - Thu, Jan 28
2:00 pm - 8:42 pmITH Ithaca Tompkins County-CHS Charleston
6h 42m1 stop New York John F Kennedy Intl
6:00 am - 1:15 pmCHS Charleston-ITH Ithaca Tompkins County
7h 15m1 stop New York John F Kennedy Intl
$339Delta
Sat, Oct 24 - Wed, Oct 28
6:15 am - 3:01 pmITH Ithaca Tompkins County-GSP Greenville
8h 46m2 stops Washington, D.C. Dulles Intl Newark
7:43 pm - 11:44 pmGSP Greenville-ITH Ithaca Tompkins County
4h 01m1 stop Washington, D.C. Dulles Intl
$374United Airlines
Sat, Oct 24 - Wed, Oct 28
6:15 am - 3:01 pmITH Ithaca Tompkins County-GSP Greenville
8h 46m2 stops Washington, D.C. Dulles Intl Newark
11:51 am - 7:02 pmGSP Greenville-ITH Ithaca Tompkins County
7h 11m2 stops Newark Washington, D.C. Dulles Intl
$398United Airlines
Thu, Jan 7
9:45 am - 2:22 pmITH Ithaca Tompkins County-GSP Greenville
4h 37m1 stop Washington, D.C. Dulles Intl
$284United Airlines
Tue, Jan 5
5:55 am - 2:49 pmITH Ithaca Tompkins County-GSP Greenville
8h 54m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
$289Delta
Wed, Jan 6
5:55 am - 2:49 pmITH Ithaca Tompkins County-GSP Greenville
8h 54m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
$289Delta
Sun, Jan 10
2:00 pm - 11:37 pmITH Ithaca Tompkins County-GSP Greenville
9h 37m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
$289Delta
Sat, Jan 9
5:55 am - 3:07 pmITH Ithaca Tompkins County-GSP Greenville
9h 12m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
$289Delta
Fri, Jan 8
2:00 pm - 11:37 pmITH Ithaca Tompkins County-GSP Greenville
9h 37m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
$289Delta
Thu, Jan 7
2:00 pm - 11:37 pmITH Ithaca Tompkins County-GSP Greenville
9h 37m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
$289Delta
Fri, Nov 6
6:00 am - 10:06 amITH Ithaca Tompkins County-CHS Charleston
4h 06m1 stop Washington, D.C. Dulles Intl
$296United Airlines
Mon, Dec 28
5:45 am - 11:48 amITH Ithaca Tompkins County-CHS Charleston
6h 03m1 stop New York John F Kennedy Intl
$324Delta
Thu, Nov 5
6:00 am - 10:06 amITH Ithaca Tompkins County-CHS Charleston
4h 06m1 stop Washington, D.C. Dulles Intl
$333United Airlines
Thu, Oct 15 - Mon, Oct 19
6:15 am - 9:47 amITH Ithaca Tompkins County-CAE Columbia Metropolitan
3h 32m1 stop Washington, D.C. Dulles Intl
3:03 pm - 6:53 pmCAE Columbia Metropolitan-ITH Ithaca Tompkins County
3h 50m1 stop Washington, D.C. Dulles Intl
$446United Airlines
Thu, Oct 15 - Mon, Oct 19
6:15 am - 9:47 amITH Ithaca Tompkins County-CAE Columbia Metropolitan
3h 32m1 stop Washington, D.C. Dulles Intl
6:15 am - 6:53 pmCAE Columbia Metropolitan-ITH Ithaca Tompkins County
12h 38m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$685United Airlines
Thu, Oct 15 - Mon, Oct 19
10:27 am - 9:09 pmITH Ithaca Tompkins County-CAE Columbia Metropolitan
10h 42m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
6:15 am - 6:53 pmCAE Columbia Metropolitan-ITH Ithaca Tompkins County
12h 38m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$840United Airlines
Sun, Oct 11 - Sun, Oct 11
5:40 am - 12:11 pmITH Ithaca Tompkins County-CHS Charleston
6h 31m1 stop New York John F Kennedy Intl
5:40 pm - 11:01 pmCHS Charleston-ITH Ithaca Tompkins County
5h 21m1 stop New York John F Kennedy Intl
$1,258Delta
Sun, Oct 11 - Sun, Oct 11
5:40 am - 1:11 pmITH Ithaca Tompkins County-CHS Charleston
7h 31m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
5:40 pm - 11:01 pmCHS Charleston-ITH Ithaca Tompkins County
5h 21m1 stop New York John F Kennedy Intl
$1,263Delta
Sun, Oct 11 - Sun, Oct 11
6:15 am - 2:02 pmITH Ithaca Tompkins County-CHS Charleston
7h 47m2 stops Washington, D.C. Dulles Intl Newark
3:10 pm - 11:44 pmCHS Charleston-ITH Ithaca Tompkins County
8h 34m2 stops Newark Washington, D.C. Dulles Intl
$1,651United Airlines
KAYAK's insights & trends for Ithaca to South Carolina flights
Get data-powered insights and trends into flights from Ithaca to South Carolina to help you find the cheapest flights, the best time to fly and much more.
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Cheapest flight | $284 |
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Reviews of the top airline flying from Ithaca to South Carolina
See real verified KAYAK customer reviews for airlines flying from Ithaca to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
7.8
DeltaOverall score based on 8654 reviews
7.2Food
8.1Boarding
8.5Crew
7.8Comfort
7.8Entertainment
Airline reviews
Flight was very delayed so I was able to get on an earlier flight via stand-by. Crew communicated effectively around delay and worked to make customers comfortable. Wifi was ok, streaming TV was great. App functionality broke down once I was moved to stand-by on earlier flight.
6.0 GoodElliot, Oct 2026
Flight was very delayed so I was able to get on an earlier flight via stand-by. Crew communicated effectively around delay and worked to make customers comfortable. Wifi was ok, streaming TV was great. App functionality broke down once I was moved to stand-by on earlier flight.
Late flight, screens not working and still had to pay for a drink
Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.
For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.
I am still at the Airport! Delayed Delayed and Delyaed
The landing was the worst I’ve experienced with a flight.
It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.
All good on Delta's part. Passengers could be a little more courteous to each other.
The pilots were good. Disappointing when planes don't have electrical ports
No complaints - left 20 minutes later than planned but still arrived on time.
More options for your flight from Ithaca to South Carolina
Complete your trip to South Carolina with a hotel stay or car rental
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Cabin class types available on flights to South Carolina
Cabin classes available on flights to South Carolina. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights from other airports in Ithaca to South Carolina
Flights from all airports in Ithaca to South Carolina. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights to other popular destinations
The most popular flights on KAYAK according to clicks in the last 2 weeks. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights from Ithaca to popular cities in South Carolina
Flights from Ithaca to Charlestonfrom $498
Flights from Ithaca to Charlottefrom $339
Flights from Ithaca to Columbiafrom $446
Flights from Ithaca to Greenvillefrom $572
Flights from Ithaca to Myrtle Beachfrom $518
Flights from Ithaca to Savannahfrom $548