$173 Find Cheap Flights from Jacksonville to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Jacksonville to South America departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Jacksonville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$693
Bogotá
Bogotá1 stop$527
Buenos Aires
Buenos Aires2 stops$982
Santiago
Santiago2 stops$874
Cartagena
Cartagena1 stop$295
Quito
Quito1 stop$501
Guayaquil
Guayaquil1 stop$398
Cali
Cali2 stops$573
Cusco
Cusco3 stops$939
Barranquilla
Barranquilla1 stop$550
Montevideo
Montevideo2 stops$1,145
Lima
Lima1 stop$693
Bogotá
Bogotá1 stop$527
Buenos Aires
Buenos Aires2 stops$982
Santiago
Santiago2 stops$874
Cartagena
Cartagena1 stop$295
Quito
Quito1 stop$501
Guayaquil
Guayaquil1 stop$398
Cali
Cali2 stops$573
Cusco
Cusco3 stops$939
Barranquilla
Barranquilla1 stop$550
Montevideo
Montevideo2 stops$1,145

Book Cheap Jacksonville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Jacksonville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Jacksonville to South America

Sun, Aug 30 - Thu, Sep 3
JetBlue Logo
7:10 am - 11:35 am
JAX
-
CTG
5h 25m
1 stop
JetBlue Logo
12:35 pm - 7:57 pm
CTG
-
JAX
6h 22m
1 stop
$295JetBlue
Sat, Aug 29 - Wed, Sep 2
American Airlines Logo
6:00 am - 2:15 pm
JAX
-
CTG
9h 15m
1 stop
American Airlines Logo
1:35 pm - 12:34 am
CTG
-
JAX
9h 59m
1 stop
$321American Airlines
Sun, Sep 20 - Thu, Sep 24
United Airlines Logo
7:05 am - 9:10 pm
JAX
-
MDE
15h 05m
1 stop
United Airlines Logo
9:45 am - 11:20 pm
MDE
-
JAX
12h 35m
1 stop
$397United Airlines
Tue, Sep 8 - Tue, Sep 15
United Airlines Logo
7:05 am - 9:10 pm
JAX
-
MDE
15h 05m
1 stop
United Airlines Logo
9:45 am - 8:54 pm
MDE
-
JAX
34h 09m
3 stops
$402United Airlines
Mon, Oct 19 - Sun, Nov 15
Multiple Airlines Logo
7:00 pm - 6:35 am
JAX
-
UIO
12h 35m
1 stop
Multiple Airlines Logo
5:20 pm - 2:41 pm
UIO
-
JAX
21h 21m
1 stop
$501Multiple Airlines
Sat, Oct 24 - Sun, Nov 22
Multiple Airlines Logo
7:00 pm - 6:55 am
JAX
-
UIO
12h 55m
1 stop
Multiple Airlines Logo
5:20 pm - 11:13 am
UIO
-
JAX
17h 53m
1 stop
$510Multiple Airlines
Wed, Oct 7 - Mon, Oct 12
Delta Logo
7:15 am - 5:50 pm
JAX
-
BOG
11h 35m
2 stops
Delta Logo
8:40 am - 11:56 pm
BOG
-
JAX
14h 16m
2 stops
$589Delta
Fri, Oct 16 - Mon, Oct 19
Delta Logo
5:05 am - 5:50 pm
JAX
-
BOG
13h 45m
2 stops
Delta Logo
8:40 am - 8:37 am
BOG
-
JAX
22h 57m
2 stops
$599Delta
Tue, Sep 1 - Thu, Sep 10
LATAM Airlines Logo
12:59 pm - 5:00 am
JAX
-
LIM
17h 01m
1 stop
LATAM Airlines Logo
12:05 pm - 9:38 am
LIM
-
JAX
20h 33m
1 stop
$693LATAM Airlines
Sun, Dec 6 - Wed, Dec 9
LATAM Airlines Logo
7:30 am - 6:00 am
JAX
-
LIM
22h 30m
2 stops
LATAM Airlines Logo
12:00 pm - 12:02 am
LIM
-
JAX
12h 02m
1 stop
$702LATAM Airlines
Booking Insights

KAYAK's insights & trends for Jacksonville to South America flights

Get data-powered insights and trends into flights from Jacksonville to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Jacksonville to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Jacksonville to South America is February, when tickets cost $154 (return) on average. On the other hand, the most expensive months are January and October, when the average cost of round-trip tickets is $426 and $426 respectively.

Good to know

Low seasonJanuary
Cheapest flight$173
Best time to beat the crowds with an average 8% drop in price.
Flight from Jacksonville to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Jacksonville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Jacksonville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Jacksonville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Jacksonville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Jacksonville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Jacksonville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Jacksonville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Jacksonville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Jacksonville to South America

 
Need help choosing which airline to fly with from Jacksonville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8465 reviews
7.8Entertainment
7.2Food
8.1Boarding
8.5Crew
7.8Comfort
Airline reviews

I had only one problem. The temperature on the flight was too COLD. I froze throughout the flight. I thought it might be only my problem but when I went to the restroom during the flight, I saw several people huddling in their jackets. A couple had their winter coats on and I was jealous since I had only a very light jacket.

8.0 ExcellentRoseanne, Jul 2026
FLL - ATL
Read more Delta reviews

I had only one problem. The temperature on the flight was too COLD. I froze throughout the flight. I thought it might be only my problem but when I went to the restroom during the flight, I saw several people huddling in their jackets. A couple had their winter coats on and I was jealous since I had only a very light jacket.

Five hour delays every hour, I wish it were all at once

Got rerouted from a straight flight from Orlando to Atlanta to Knoxville to a flight from Orlando to Detroit to Knoxville! Seriously!! Flight delay out of Detroit! Long day for what should have been a pretty easy travel day!

Aside from a completely packed plane, I really have no complaints.

The flight was very good and the staff was very friendly and helpful!

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The food is terrible. The staff is wonderful. Comfort is good.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

Flight was on time, the staff was personable & professional, & the plane arrived on time.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Very slow boarding, 1 hour late - uncomfortable chairs and crew barely speaking english even at the airport!

It was fine. no food or entertainment , but was only a 40 minute flight.

Everything was as you would expect in coach - fine. Flight was close to on time.

There was a piece of plastic baked into my buttermilk biscuit! I have a pictures. The flight attendants in first class were really apologetic, and tried to rectify the situation. I I am very appreciative that they were able to give me some packets of pretzels and gummy bears. I understand they don't personally handle the food until warming it up so I know it wasn't their fault. I don't know whether it was a newer aircraft, or different food packaging, but I was happy that when the food was being warmed up - it didn't smell like plastic. Jokes on me with finding plastic in my food.

Horrible experience. They delayed our flight 7 hours!! We had to seat at the airport with kids on 4th July all day!

Horrible I am at almost 2,000,000 miles on United. This was probably the worst flight ever. An hour and a half before takeoff I get a message that they’re changing the plane and I no longer have a seat in Polaris business Supposedly, there was a problem with the plane, but then there was no other plane Finally, they decided to bring a plane from Newark to Washington Dulles Of course the original flight was at 10:45 PM so by the time the plane got there it was 12:30 AM. It had not been cleaned. It had not been catered. They don’t really have people available to do those things when it’s not pre-programmed at 1 o’clock in the morning. The crew had to be changed And the new plane held 28 fewer people than the scheduled plane There is no way you can hate United Airlines enough The people at the gate were actually just fine, but it was management who was completely useless And did they send extra help to the people at the gate? Did they send supervisors? Of course not. Just don’t take United find somebody else or buy a boat

We used Kayak to reserve our tickets and specifically checked the luggage option which was a more expensive option. When we arrived at the terminal we had to pay an extra $90 per suitcase for the three passengers. This has been a pattern for the past 3 years. Why charge for a more expensive luggage option, and the ticket price not include luggage?

6 1/2 hours from Tampa to SFO on a Boeing 737. Cramped. No Service. No real food. One pass for coffee at the beginning and a second pass THREE hours later. And check-in in Tampa was nasty even by United standards. And I am at almost TWO million miles on United. It's a non-stop. But terrible service.

This is for UA2274 from Houston to Sacramento. The flight was delayed arriving due to mechanical issues so we left about 3 hours later than scheduled. When boarding the plane the temperature inside was excessive - likely close to 100. Pilot apologized and said it was going to improve at altitude, which it did. But before that I honestly thought there might have been more delays removing passengers made ill from the heat. We were delayed leaving due to another mechanical issue. There was not water on the plane due to a panel that was not secured. They did that quickly, but the combination of mechanical issues was rather disturbing and did not reflect well on United.

Flight was delayed in the gate by 5 hours and ultimately cancelled- rebooking service by United agents was terrible

United domestic flight was better than international flight. There was no switch to control Ac In international united flight. Food was also average, Air canada food was much better than united.

They cancelled our flight at the last minute due to mechanical issues. Rather, they “delayed” it till the next morning. A pain in the neck when traveling with two young children. Crew was really nice, which made up for it somewhat. This is the second flight from delta that was cancelled this year. Definitely going to fly another airline when possible

Noticing spectacular about the flight. It got me fro m point a to b. High priced

Would have been good to have the live TV outside of the continental United States as AA was promoting they are sponsors of the Fifa World Cup only for the live coverage to end.

Terrible check in experience in Miami airport by a so-called supervisor. Food came and they were picking up trash within 5 mins. Did not get fed again for about 6 hours. No chance to buy anything on board, horrible experience. Flight attendants have no control over passengers dropping off bags closer to the exit, not close to their seat.

American Airlines changed are gate no fewer than four times. Walking back and forth from one concourse to another was exhausting, especially after all the flight delays.

I cancelled this flight 2 days before departure but I followed your texts and emails and IF you were correct this flight turned into a nightmare.

Awful. Original flight was delayed 5 hours. Had to to take a connecting flight instead of direct. Had a 4 hour layover. I missed all of my morning meetings getting in 5 hours later than I was supposed to and had to change to take a later flight the next day to get them back in which cia time another $150.

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

I was late from Jacksonville, FL but the limited interaction I had with the Philly crew was great.

Delayed 4 hours from Charlotte to Nashville. Could have driven there faster. Information provided by AA was sparse.

Gate change was a little tough but it was a good flight otherwise

Great flight, great service but most of all- our luggage made the trip with us.,

Everything you need to know for your flight to South America

Information on your arrival and departure airports