$161 Find Cheap Flights from Jacksonville to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Jacksonville to South America departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Jacksonville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$616
Bogotá
Bogotá1 stop$556
Buenos Aires
Buenos Aires2 stops$1,033
Santiago
Santiago2 stops$921
Cartagena
Cartagena1 stop$377
Quito
Quito1 stop$494
Guayaquil
Guayaquil1 stop$418
Cali
Cali2 stops$584
Cusco
Cusco2 stops$979
Barranquilla
Barranquilla1 stop$426
Montevideo
Montevideo2 stops$1,507
Lima
Lima1 stop$616
Bogotá
Bogotá1 stop$556
Buenos Aires
Buenos Aires2 stops$1,033
Santiago
Santiago2 stops$921
Cartagena
Cartagena1 stop$377
Quito
Quito1 stop$494
Guayaquil
Guayaquil1 stop$418
Cali
Cali2 stops$584
Cusco
Cusco2 stops$979
Barranquilla
Barranquilla1 stop$426
Montevideo
Montevideo2 stops$1,507

Book Cheap Jacksonville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Jacksonville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Jacksonville to South America

Mon, Aug 31 - Thu, Sep 3
JetBlue Logo
7:10 am - 11:35 am
JAX
-
CTG
5h 25m
1 stop
JetBlue Logo
12:35 pm - 7:57 pm
CTG
-
JAX
6h 22m
1 stop
$377JetBlue
Sat, Aug 29 - Wed, Sep 2
American Airlines Logo
4:35 pm - 12:35 pm
JAX
-
CTG
21h 00m
2 stops
American Airlines Logo
1:35 pm - 11:39 pm
CTG
-
JAX
9h 04m
1 stop
$396American Airlines
Thu, Nov 5 - Mon, Nov 16
United Airlines Logo
7:00 am - 10:10 pm
JAX
-
MDE
15h 10m
1 stop
United Airlines Logo
10:40 am - 11:13 pm
MDE
-
JAX
12h 33m
1 stop
$397United Airlines
Thu, Nov 5 - Mon, Nov 16
United Airlines Logo
7:00 am - 10:10 pm
JAX
-
MDE
15h 10m
1 stop
United Airlines Logo
10:40 am - 11:11 am
MDE
-
JAX
24h 31m
2 stops
$402United Airlines
Sun, Jan 17 - Wed, Jan 20
Delta Logo
7:30 am - 11:55 pm
JAX
-
MDE
16h 25m
2 stops
Delta Logo
5:05 am - 9:38 pm
MDE
-
JAX
16h 33m
2 stops
$410Delta
Sun, Nov 1 - Sat, Nov 14
Multiple Airlines Logo
11:15 am - 6:55 am
JAX
-
UIO
19h 40m
1 stop
Multiple Airlines Logo
5:20 pm - 9:52 am
UIO
-
JAX
16h 32m
1 stop
$494Multiple Airlines
Fri, Sep 4 - Fri, Sep 11
Multiple Airlines Logo
5:35 pm - 6:35 am
JAX
-
UIO
14h 00m
1 stop
Multiple Airlines Logo
5:25 pm - 2:26 pm
UIO
-
JAX
20h 01m
1 stop
$525Multiple Airlines
Wed, Jan 13 - Thu, Jan 21
Delta Logo
5:30 am - 6:00 pm
JAX
-
BOG
12h 30m
2 stops
Delta Logo
3:40 pm - 8:47 am
BOG
-
JAX
17h 07m
1 stop
$565Delta
Mon, Oct 26 - Mon, Nov 2
LATAM Airlines Logo
7:59 pm - 5:00 am
JAX
-
LIM
10h 01m
1 stop
LATAM Airlines Logo
12:00 pm - 11:56 pm
LIM
-
JAX
11h 56m
1 stop
$616LATAM Airlines
Mon, Oct 26 - Sun, Nov 1
LATAM Airlines Logo
7:59 pm - 5:00 am
JAX
-
LIM
10h 01m
1 stop
LATAM Airlines Logo
12:15 am - 5:54 pm
LIM
-
JAX
17h 39m
2 stops
$634LATAM Airlines
Booking Insights

KAYAK's insights & trends for Jacksonville to South America flights

Get data-powered insights and trends into flights from Jacksonville to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Jacksonville to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Jacksonville to South America is April, when tickets cost $627 (return) on average. On the other hand, the most expensive months are December and June, when the average cost of round-trip tickets is $856 and $831 respectively.

How far in advance should I book a flight from Jacksonville to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Jacksonville to South America, you should book around 5 weeks before departure, which saves you about 26% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low season

January

Cheapest flight

$161
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from Jacksonville to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Jacksonville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Jacksonville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Jacksonville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Jacksonville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Jacksonville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Jacksonville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Jacksonville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Jacksonville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Jacksonville to South America

 
Need help choosing which airline to fly with from Jacksonville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8483 reviews
7.8Entertainment
7.8Comfort
7.2Food
8.5Crew
8.1Boarding
Airline reviews

My flight was canceled, and instead of rebooking me on a non-stop first-class flight for the same day, which I originally had, Delta rebooked me on a one-stop flight for the following day. When I checked the Delta app, I noticed that there were available flights for both the same day and the next day. I believe this indicates poor management on their part.

2.0 MediocreAnonymous, Jul 2026
FLL - LGA
Read more Delta reviews

My flight was canceled, and instead of rebooking me on a non-stop first-class flight for the same day, which I originally had, Delta rebooked me on a one-stop flight for the following day. When I checked the Delta app, I noticed that there were available flights for both the same day and the next day. I believe this indicates poor management on their part.

My flight was delayed and I got back around 3.5 hours later than expected. I had to get a new connecting flight

I had only one problem. The temperature on the flight was too COLD. I froze throughout the flight. I thought it might be only my problem but when I went to the restroom during the flight, I saw several people huddling in their jackets. A couple had their winter coats on and I was jealous since I had only a very light jacket.

Aside from a completely packed plane, I really have no complaints.

The flight was very good and the staff was very friendly and helpful!

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The food is terrible. The staff is wonderful. Comfort is good.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

Flight was on time, the staff was personable & professional, & the plane arrived on time.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Very slow boarding, 1 hour late - uncomfortable chairs and crew barely speaking english even at the airport!

It was fine. no food or entertainment , but was only a 40 minute flight.

Everything was as you would expect in coach - fine. Flight was close to on time.

There was a piece of plastic baked into my buttermilk biscuit! I have a pictures. The flight attendants in first class were really apologetic, and tried to rectify the situation. I I am very appreciative that they were able to give me some packets of pretzels and gummy bears. I understand they don't personally handle the food until warming it up so I know it wasn't their fault. I don't know whether it was a newer aircraft, or different food packaging, but I was happy that when the food was being warmed up - it didn't smell like plastic. Jokes on me with finding plastic in my food.

Horrible experience. They delayed our flight 7 hours!! We had to seat at the airport with kids on 4th July all day!

Horrible I am at almost 2,000,000 miles on United. This was probably the worst flight ever. An hour and a half before takeoff I get a message that they’re changing the plane and I no longer have a seat in Polaris business Supposedly, there was a problem with the plane, but then there was no other plane Finally, they decided to bring a plane from Newark to Washington Dulles Of course the original flight was at 10:45 PM so by the time the plane got there it was 12:30 AM. It had not been cleaned. It had not been catered. They don’t really have people available to do those things when it’s not pre-programmed at 1 o’clock in the morning. The crew had to be changed And the new plane held 28 fewer people than the scheduled plane There is no way you can hate United Airlines enough The people at the gate were actually just fine, but it was management who was completely useless And did they send extra help to the people at the gate? Did they send supervisors? Of course not. Just don’t take United find somebody else or buy a boat

We used Kayak to reserve our tickets and specifically checked the luggage option which was a more expensive option. When we arrived at the terminal we had to pay an extra $90 per suitcase for the three passengers. This has been a pattern for the past 3 years. Why charge for a more expensive luggage option, and the ticket price not include luggage?

6 1/2 hours from Tampa to SFO on a Boeing 737. Cramped. No Service. No real food. One pass for coffee at the beginning and a second pass THREE hours later. And check-in in Tampa was nasty even by United standards. And I am at almost TWO million miles on United. It's a non-stop. But terrible service.

This is for UA2274 from Houston to Sacramento. The flight was delayed arriving due to mechanical issues so we left about 3 hours later than scheduled. When boarding the plane the temperature inside was excessive - likely close to 100. Pilot apologized and said it was going to improve at altitude, which it did. But before that I honestly thought there might have been more delays removing passengers made ill from the heat. We were delayed leaving due to another mechanical issue. There was not water on the plane due to a panel that was not secured. They did that quickly, but the combination of mechanical issues was rather disturbing and did not reflect well on United.

Flight was delayed in the gate by 5 hours and ultimately cancelled- rebooking service by United agents was terrible

United domestic flight was better than international flight. There was no switch to control Ac In international united flight. Food was also average, Air canada food was much better than united.

They cancelled our flight at the last minute due to mechanical issues. Rather, they “delayed” it till the next morning. A pain in the neck when traveling with two young children. Crew was really nice, which made up for it somewhat. This is the second flight from delta that was cancelled this year. Definitely going to fly another airline when possible

Noticing spectacular about the flight. It got me fro m point a to b. High priced

Quick flight. No time to stress over it. Over before it begins.

- flight was delayed several hours due to weather (understandable) - flight delayed further and we were told by attendants "we are not sure where the pilots are but they are on their way" as we have to find different pilots for the flight - announcements over the PA were somewhat unprofessional by the attendants, seems they need more training and were not reading off the script. They showed their young age and immaturity in their communications with the passengers. They were not clear and lacked professional communication language. - going from a hub to hub we were also parked at the tarmac at ohare for an additional hour and kept being told "few more minutes". Please just let the passengers know the real wait time instead of hiding the truth. We understand there is traffic and weather delays, but we just want transparency. There are several logistics of our lives that revolve around what the attendants and pilots are sharing with us but they are not being transparant.

Not great. I understand delays happen due to weather and crew issues, but it was unacceptable that no agents were available at the counters inside the airport for customer service or help getting on a standby list. The app was not helpful either. I stood in line for an hour waiting for someone to show up at the gate to help me get on a standby flight. Customer care does not seem to be a priority.

As I said I never took the flight back from due to earlier delayed that prevented from taking the second trip back and nobody helped me to rebook from kayak

Awful. Original flight was delayed 5 hours. Had to to take a connecting flight instead of direct. Had a 4 hour layover. I missed all of my morning meetings getting in 5 hours later than I was supposed to and had to change to take a later flight the next day to get them back in which cia time another $150.

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

I was late from Jacksonville, FL but the limited interaction I had with the Philly crew was great.

Delayed 4 hours from Charlotte to Nashville. Could have driven there faster. Information provided by AA was sparse.

Gate change was a little tough but it was a good flight otherwise

Great flight, great service but most of all- our luggage made the trip with us.,

My checked in luggage cost was $59, almost ticket price. The first 13 rows were empty, but fly attendant did not alow women with little boy change her middle sit, sweet boy was crying, I am so sorry for mother and passengers. At the end of the flight the cabin became impossible cold. Only good was timing of departure and early landing, but it suppose to be normal.

I tried to book a flight with Jet Blue. Your third party company hijacked my attempt with a website that looked like I was booking with Jet Blue. I realized it when I paid. I tried to cancel and was told by a man in India that there were no refunds. $735 stolen, Thanks Kayak!

The flight out was delayed from 3:40pm to 5pm and again to 8pm. We boarded after 5pm, had to disembark because they could not get the Engine started, then we switched gates and got a new plane and did not board until after 8pm.

Boarding was easy. Provided drinks and snacks. Good aircraft and staff

Flight was quick, less time than expected, and the attendants all friendly and helpful. We had paid extra for more leg room and were very comfortable. Haven't flown JetBlue in quite a while. Glad to be back!

JetBlue not only has the most comfortable planes, but also used to have the best customer service. Lorie Wright, the lady at the gate was very rude not only to me, but to other passengers as well. Her colleague, the gentleman was also not very friendly. They both were acting like they were doing passengers a favor. The crew on board was very nice.

Direct tv did not work on flight Short flight so no good service offered Arrived early to destination and had to wait for gate to open. Deplaned LATER than if we arrived on time!! Poor planning Jet blue has had something go wrong on every flight I’ve taken with them in last five years. Terribly run airline

My experience with JetBlue was fine BUT I am very upset with Kayak! JetBlue had delayed our scheduled departure by an hour and you NEVER notified me of the change. I did not hear directly from JetBlue because the trip was booked through Kayak, a mistake I will not repeat. Your reminder of the our trip last week still had the WRONG departure time. Our return trip has also changed, and again no notice from you.

Not having an assigned seat until boarding and then having to check my bag.

I purchased ticket so our daughter ( a minor) can sit next to her mother. No help at gate after kayak insisted that this could be done. She ended sitting by herself

Everything you need to know for your flight to South America

Information on your arrival and departure airports