$159 Find Cheap Flights from Jacksonville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Jacksonville to South America departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Jacksonville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$592
Bogotá
Bogotá1 stop$452
Buenos Aires
Buenos Aires2 stops$1,157
Santiago
Santiago1 stop$771
Cartagena
Cartagena1 stop$283
Quito
Quito2 stops$449
Guayaquil
Guayaquil1 stop$369
Cali
Cali2 stops$536
Montevideo
Montevideo2 stops$1,053
Barranquilla
Barranquilla2 stops$622
Lima
Lima1 stop$592
Bogotá
Bogotá1 stop$452
Buenos Aires
Buenos Aires2 stops$1,157
Santiago
Santiago1 stop$771
Cartagena
Cartagena1 stop$283
Quito
Quito2 stops$449
Guayaquil
Guayaquil1 stop$369
Cali
Cali2 stops$536
Montevideo
Montevideo2 stops$1,053
Barranquilla
Barranquilla2 stops$622

Book Cheap Jacksonville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Jacksonville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Jacksonville to South America

Sun, Feb 22 - Sat, Feb 28
American Airlines Logo
6:00 am - 1:30 pm
JAX
-
CTG
7h 30m
1 stop
American Airlines Logo
4:30 pm - 9:03 am
CTG
-
JAX
16h 33m
1 stop
$283American Airlines
Sun, Feb 22 - Sat, Feb 28
American Airlines Logo
9:43 am - 1:30 pm
JAX
-
CTG
27h 47m
1 stop
American Airlines Logo
4:30 pm - 9:03 am
CTG
-
JAX
16h 33m
1 stop
$286American Airlines
Sun, Feb 22 - Thu, Feb 26
United Airlines Logo
6:25 am - 10:05 pm
JAX
-
MDE
15h 40m
1 stop
United Airlines Logo
10:45 am - 9:32 pm
MDE
-
JAX
10h 47m
1 stop
$306United Airlines
Sat, Feb 28 - Mon, Mar 2
United Airlines Logo
6:25 am - 10:05 pm
JAX
-
MDE
15h 40m
1 stop
United Airlines Logo
10:45 am - 10:49 am
MDE
-
JAX
24h 04m
2 stops
$311United Airlines
Wed, Feb 25 - Sat, Mar 7
Delta Logo
5:30 am - 2:17 pm
JAX
-
CTG
8h 47m
1 stop
Delta Logo
3:32 pm - 10:58 pm
CTG
-
JAX
7h 26m
1 stop
$329Delta
Wed, Feb 25 - Wed, Mar 4
Delta Logo
6:30 am - 2:17 pm
JAX
-
CTG
7h 47m
1 stop
Delta Logo
7:05 am - 8:44 am
CTG
-
JAX
25h 39m
2 stops
$332Delta
Tue, Apr 21 - Mon, May 4
Multiple Airlines Logo
11:12 am - 11:40 pm
JAX
-
UIO
13h 28m
2 stops
Multiple Airlines Logo
5:25 pm - 10:16 am
UIO
-
JAX
15h 51m
1 stop
$449Multiple Airlines
Tue, May 12 - Tue, May 19
Multiple Airlines Logo
6:10 pm - 5:30 am
JAX
-
BOG
12h 20m
1 stop
Multiple Airlines Logo
7:10 am - 9:19 pm
BOG
-
JAX
13h 09m
1 stop
$452Multiple Airlines
Sat, May 2 - Fri, May 8
LATAM Airlines Logo
11:27 am - 8:15 am
JAX
-
LIM
21h 48m
2 stops
LATAM Airlines Logo
12:00 pm - 12:02 am
LIM
-
JAX
11h 02m
1 stop
$630LATAM Airlines
Wed, Mar 25 - Mon, Mar 30
LATAM Airlines Logo
1:17 pm - 9:20 pm
JAX
-
LIM
9h 03m
1 stop
LATAM Airlines Logo
12:15 am - 5:43 pm
LIM
-
JAX
16h 28m
2 stops
$637LATAM Airlines
Booking Insights

KAYAK's insights & trends for Jacksonville to South America flights

Get data-powered insights and trends into flights from Jacksonville to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Jacksonville to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Jacksonville to South America is September, when tickets cost $606 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $798 and $783 respectively.

How far in advance should I book a flight from Jacksonville to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Jacksonville to South America, you should book around 7 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$159
Best time to beat the crowds with an average 10% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Jacksonville to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Jacksonville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Jacksonville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Jacksonville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Jacksonville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Jacksonville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Jacksonville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Jacksonville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Jacksonville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Jacksonville to South America

 
Need help choosing which airline to fly with from Jacksonville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8128 reviews
8.5Crew
7.8Entertainment
8.1Boarding
7.2Food
7.9Comfort
Airline reviews

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

10.0 ExcellentSteven, Jan 2026
FLL - CVG
Read more Delta reviews

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

No WiFi. Comfort plus should have alcohol provided, crew only offered water or tea. Who the heck wants tea?

I have diamond medallion status and usually we are in comfort plus . We were in main this time ( which was fine ) and my husband wanted wine . I have at least 10 vouchers for drinks that are good for this year and next! The attendant would not take the picture of the voucher as proof and never came back to check as She asked me to pull it up on delta Wi-Fi. Instead my husband just used his Amex to buy the wine . Disappointing!!!

Food is basically Sun Chips, cookies or Cheezits. I had an exit row seat so I had plenty of room. The crew was very nice and efficient. Pilot kept us informed. Pretty good flight.

The only thing nice I can say is the flight crew was really nice and apologetic about the situation. They shared as much information as they had and advised us on what we could do about missing connecting flights. The boarding process was so slow. The gate agent was working by herself and should have had someone working with her. It took almost an hour to board because she was trying to board a full flight of people and provide customer service to everyone who was flying standby and/or had questions. It was really chaotic. This didn't help the fact that we were delayed and folks were missing connections the longer it took.

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

Little warm on the plane and delayed for an hour

UGH I HAD TO MISS MY FIRST FLIGHT TO TAMPA CAUSE OF THE 10 MINUTE DELAY OF THE ORLANDO TO MIAMI ONE SO THEY HAD ME GET ANOTHER TICKET. I AM NOT HAPPY AT ALL BECAUSE IT MADE ME MISS MY CONNECTING FLIGHT FROM TAMPA TO LONDON AND FORCED ME TO MISS A DAY AT MY ROOM IN THE UK.

Wish they didnt delay off-boarding for 10 minutes so i could connect to my flight from miami to tampa

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

Boarding was organized and timely. Food was mediocre, especially for first class travel.

We were 4+ hours delayed. AA is absolutely obnoxious. They just kept pushing back the time to the point where we did not get into Vegas until after midnight when we were supposed to arrive like 845pm.

My last flight on 25 Dec, it’s Christmas Day, everyone happy and very good mood. I really enjoy traveling with Americans Airlines from Miami to Minneapolis my home town after long flight from lhe to Doha then Miami. Thank you again to make my travels comfortable and relaxed. Best regards

Everything you need to know for your flight to South America

Information on your arrival and departure airports