$176 Find Cheap Flights from Jacksonville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Jacksonville to South America departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Jacksonville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$567
Bogotá
Bogotá1 stop$498
Buenos Aires
Buenos Aires1 stop$1,055
Cartagena
Cartagena2 stops$512
Santiago
Santiago1 stop$684
Quito
Quito1 stop$583
Cali
Cali2 stops$530
Guayaquil
Guayaquil2 stops$556
Cusco
Cusco2 stops$887
Montevideo
Montevideo2 stops$1,026
Barranquilla
Barranquilla2 stops$632
Lima
Lima1 stop$567
Bogotá
Bogotá1 stop$498
Buenos Aires
Buenos Aires1 stop$1,055
Cartagena
Cartagena2 stops$512
Santiago
Santiago1 stop$684
Quito
Quito1 stop$583
Cali
Cali2 stops$530
Guayaquil
Guayaquil2 stops$556
Cusco
Cusco2 stops$887
Montevideo
Montevideo2 stops$1,026
Barranquilla
Barranquilla2 stops$632

Book Cheap Jacksonville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Jacksonville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Jacksonville to South America

Sat, Sep 6 - Wed, Sep 10
JetBlue Logo
12:50 pm - 2:05 pmJAX-MDE
26h 15m2 stops
JetBlue Logo
1:30 pm - 11:55 amMDE-JAX
21h 25m2 stops
$474JetBlue
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Tue, Oct 14 - Wed, Oct 22
Delta Logo
10:04 am - 7:15 pmJAX-BOG
10h 11m1 stop
Delta Logo
9:00 am - 10:22 pmBOG-JAX
12h 22m1 stop
$498Delta
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Sun, Sep 21 - Wed, Sep 24
American Airlines Logo
2:02 pm - 12:25 pmJAX-CTG
23h 23m2 stops
American Airlines Logo
1:25 pm - 9:10 amCTG-JAX
18h 45m2 stops
$512American Airlines
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Sun, Sep 21 - Wed, Sep 24
American Airlines Logo
3:25 pm - 12:25 pmJAX-CTG
22h 00m1 stop
American Airlines Logo
1:25 pm - 11:14 pmCTG-JAX
8h 49m1 stop
$516American Airlines
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Tue, Oct 14 - Mon, Oct 20
United Airlines Logo
7:00 am - 4:54 amJAX-BOG
22h 54m1 stop
United Airlines Logo
12:14 am - 10:41 amBOG-JAX
9h 27m1 stop
$519United Airlines
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Thu, Oct 23 - Sun, Oct 26
United Airlines Logo
7:00 am - 5:29 pmJAX-CLO
35h 29m2 stops
United Airlines Logo
5:01 am - 10:42 amCLO-JAX
28h 41m2 stops
$530United Airlines
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Thu, Dec 25 - Sun, Jan 4
LATAM Airlines Logo
7:00 am - 1:50 pmJAX-CTG
6h 50m1 stop
LATAM Airlines Logo
3:10 pm - 11:55 pmCTG-JAX
8h 45m1 stop
$541LATAM Airlines
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Thu, Oct 23 - Sat, Oct 25
 Logo
8:44 am - 1:11 pmJAX-MDE
29h 27m2 stops
 Logo
1:12 am - 11:07 amMDE-JAX
32h 55m3 stops
Thu, Oct 23 - Sat, Oct 25
 Logo
8:44 am - 4:39 pmJAX-MDE
32h 55m3 stops
 Logo
1:12 am - 11:07 amMDE-JAX
32h 55m3 stops
Fri, Oct 17 - Mon, Oct 20
LATAM Airlines Logo
8:11 pm - 10:55 amJAX-BOG
15h 44m2 stops
LATAM Airlines Logo
1:35 am - 6:05 pmBOG-JAX
15h 30m2 stops
$572LATAM Airlines
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Booking Insights

KAYAK's insights & trends for Jacksonville to South America flights

Get data-powered insights and trends into flights from Jacksonville to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Jacksonville to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Jacksonville to South America is January, when tickets cost $623 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $1,085 and $785 respectively.

What’s the cheapest day of the week to fly from Jacksonville to South America?

The average price of all round-trip flights from Jacksonville to South America clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Jacksonville to South America, look for departures on Mondays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from South America, Monday is the cheapest day to fly and Sunday is the most expensive.

How far in advance should I book a flight from Jacksonville to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Jacksonville to South America, you should book around 8 weeks before departure, which saves you about 26% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$176
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Jacksonville to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Jacksonville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Jacksonville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Jacksonville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Jacksonville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Jacksonville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Jacksonville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Jacksonville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Jacksonville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the morning, when round-trip flights cost $655 on average. On average, there is no price difference when choosing to fly in the morning or the evening on this flight route. The most expensive time of day to fly to South America is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $687.

Reviews of the top 3 airlines serving from Jacksonville to South America

 
Need help choosing which airline to fly with from Jacksonville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7981 reviews
7.3Food
8.2Boarding
7.9Comfort
8.5Crew
7.9Entertainment
Airline reviews

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

2.0 MediocreRosa, Jul 2025TPA - JFK
Read more Delta reviews

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

Friendly flight attendants, smooth 8-9 hours flight. Economy seats are small and uncomfortable as usual.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Flight left early and arrived early. the whole trip was excellent.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

entertainment was not good; the shoulder strap on Business class seat did not sit well across the body (more like across the neck); the food was not hot and the special meal promoted by insert in the menu was not available to us

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Food was ok, but not as good as I have had before on AA.

Pretty good. The food was just mediocre, the boarding and crew were good.

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

The plane was broken so we had to change planes.

Food was terrible, all served at once, poor quality . Wine and bread offered only once.

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

No entertainment yatem in flight at seat 51H. Would not shut down either leaving a self moving and openin and changing menus with changes in colors,images brightness levels sort of the type when you get sleep deprivation and image overload when being tortured during an interrogation. 8 hours worth of it. Unable to place backpack underneath seat on that chair. One female stewardess was excellent as she gave up her carryon's space for my backpack but the rest of the iberia crew were very sharp an chtting during the whole flight. The plane did not have hot water so nobody had coffee nor tea. The plane was not up to par to be flying.

I was late from Jacksonville, FL but the limited interaction I had with the Philly crew was great.

The delays and cancellations kept me stuck in Miami for an additional 24 hours, and the whole thing seemed extremely disorganized

The chicken adobo was a little too spicy but good otherwise. My personal opinion. Movie selection could be improved, too many horror movies. Could add a few more chick flicks! The flight was bumpy at times. We arrived a little early too! Flight attendants friendly.

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