$156 Find Cheap Flights from Jacksonville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Jacksonville to South America departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Jacksonville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$612
Bogotá
Bogotá1 stop$515
Buenos Aires
Buenos Aires2 stops$1,213
Santiago
Santiago1 stop$874
Cartagena
Cartagena1 stop$353
Quito
Quito1 stop$472
Guayaquil
Guayaquil1 stop$335
Cali
Cali2 stops$565
Cusco
Cusco2 stops$1,189
Montevideo
Montevideo2 stops$1,278
Barranquilla
Barranquilla2 stops$490
Lima
Lima2 stops$612
Bogotá
Bogotá1 stop$515
Buenos Aires
Buenos Aires2 stops$1,213
Santiago
Santiago1 stop$874
Cartagena
Cartagena1 stop$353
Quito
Quito1 stop$472
Guayaquil
Guayaquil1 stop$335
Cali
Cali2 stops$565
Cusco
Cusco2 stops$1,189
Montevideo
Montevideo2 stops$1,278
Barranquilla
Barranquilla2 stops$490

Book Cheap Jacksonville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Jacksonville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Jacksonville to South America

Sat, May 9 - Tue, May 12
Delta Logo
7:05 am - 1:15 pm
JAX
-
CTG
7h 10m
1 stop
Delta Logo
2:13 pm - 12:22 am
CTG
-
JAX
9h 09m
1 stop
$353Delta
Sat, May 9 - Tue, May 12
American Airlines Logo
6:00 am - 2:04 pm
JAX
-
CTG
9h 04m
1 stop
American Airlines Logo
1:25 pm - 9:03 am
CTG
-
JAX
18h 38m
2 stops
$358American Airlines
Sun, May 3 - Sun, May 10
American Airlines Logo
6:00 am - 2:04 pm
JAX
-
CTG
9h 04m
1 stop
American Airlines Logo
3:10 pm - 10:10 am
CTG
-
JAX
18h 00m
1 stop
$360American Airlines
Sat, May 9 - Tue, May 12
Delta Logo
7:05 am - 1:15 pm
JAX
-
CTG
7h 10m
1 stop
Delta Logo
2:13 pm - 12:22 am
CTG
-
JAX
9h 09m
1 stop
$363Delta
Sun, May 10 - Thu, May 14
United Airlines Logo
9:00 am - 9:10 pm
JAX
-
MDE
13h 10m
1 stop
United Airlines Logo
9:45 am - 8:02 pm
MDE
-
JAX
9h 17m
1 stop
$367United Airlines
Fri, Aug 21 - Sun, Aug 23
United Airlines Logo
7:05 am - 9:10 pm
JAX
-
MDE
15h 05m
1 stop
United Airlines Logo
9:45 am - 10:16 am
MDE
-
JAX
23h 31m
2 stops
$372United Airlines
Sat, Jun 27 - Sat, Jul 4
LATAM Airlines Logo
6:30 am - 9:10 pm
JAX
-
CTG
15h 40m
2 stops
LATAM Airlines Logo
9:25 am - 12:02 am
CTG
-
JAX
13h 37m
2 stops
$374LATAM Airlines
Sat, May 9 - Tue, May 12
LATAM Airlines Logo
8:05 am - 1:15 pm
JAX
-
CTG
6h 10m
1 stop
LATAM Airlines Logo
2:13 pm - 8:41 am
CTG
-
JAX
17h 28m
1 stop
$382LATAM Airlines
Mon, Jun 15 - Tue, Jun 30
GOL Logo
6:28 pm - 1:10 pm
JAX
-
GRU
17h 42m
2 stops
GOL Logo
8:55 am - 11:59 pm
GRU
-
JAX
16h 04m
2 stops
$962GOL
Fri, Jul 3 - Sun, Jul 12
GOL Logo
7:00 am - 11:05 pm
JAX
-
GRU
15h 05m
2 stops
GOL Logo
8:40 am - 12:08 am
GRU
-
JAX
16h 28m
2 stops
$1,092GOL
Booking Insights

KAYAK's insights & trends for Jacksonville to South America flights

Get data-powered insights and trends into flights from Jacksonville to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Jacksonville to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Jacksonville to South America is September, when tickets cost $622 (return) on average. On the other hand, the most expensive months are March and December, when the average cost of round-trip tickets is $813 and $798 respectively.

How far in advance should I book a flight from Jacksonville to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Jacksonville to South America, you should book around 5 weeks before departure, which saves you about 24% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$156
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from Jacksonville to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Jacksonville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Jacksonville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Jacksonville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Jacksonville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Jacksonville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Jacksonville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Jacksonville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Jacksonville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Jacksonville to South America

 
Need help choosing which airline to fly with from Jacksonville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8313 reviews
7.9Comfort
7.8Entertainment
7.2Food
8.5Crew
8.1Boarding
Airline reviews

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

10.0 ExcellentDebra, Mar 2026
PBI - ATL
Read more Delta reviews

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

The flight was great as well as the airline staff

Comfort seating was on the tight side. Maybe it was a smaller plane(?)

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Good check in process Poor information on payments at Lima airport

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

It was great. Smooth flight, comfortable, left on time and landed on time.

Perhaps this is an airport issue, but being in a takeoff queue for over an hour in the taxiing lane is unacceptable. We will definitely be seeking alternative avenues for air travel in the future.

Really good. I accidentally left my duffel on the plane and the reps were so friendly in retrieving it.

After changing the departure gate 5 times making us mo e from one side of the airport to the other and then back the flight was delayed nearly 2 hours. The male flight attendant had a bad attitude with the guest being condescending, disrespectful with people who were already on edge.

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Flights were constantly delayed. CRW took 50 minutes to get bags

Appreciate having multiple food options for allergies. Nice to have an extra seat between us for comfort.

Where do I start!! I was delayed with my flight from Dallas to Tampa. On the way back from Tampa to Dallas the flight was delayed over 4 hours+. I was put on another flight that was also delayed but not as long. Traveling on American Airlines is becoming exhausing.

I didn't end up taking this flight. I got up at 4am for a flight that was supposed to board at 6am - at 5:55am you delayed the flight to 10am. The airport is under construction so I switched to a later flight as I wasn't going to sit in the airport for 4 hours. They said the delay was due to the crew needing rest from a flight coming in late the night before - if that was the case then I think you should have delayed the flight much sooner so that passengers wouldn't get up so early and get to the airport to sit and wait.

The flight attendants and the service is getting worse by the day.

Everything you need to know for your flight to South America

Information on your arrival and departure airports