$130 Find Cheap Flights from Jacksonville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Jacksonville to South America departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Jacksonville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$567
Bogotá
Bogotá1 stop$493
Buenos Aires
Buenos Aires3 stops$1,151
Santiago
Santiago2 stops$719
Cartagena
Cartagena1 stop$313
Quito
Quito1 stop$403
Guayaquil
Guayaquil2 stops$390
Cali
Cali1 stop$550
Cusco
Cusco2 stops$819
Montevideo
Montevideo2 stops$841
Barranquilla
Barranquilla1 stop$475
Lima
Lima1 stop$567
Bogotá
Bogotá1 stop$493
Buenos Aires
Buenos Aires3 stops$1,151
Santiago
Santiago2 stops$719
Cartagena
Cartagena1 stop$313
Quito
Quito1 stop$403
Guayaquil
Guayaquil2 stops$390
Cali
Cali1 stop$550
Cusco
Cusco2 stops$819
Montevideo
Montevideo2 stops$841
Barranquilla
Barranquilla1 stop$475

Book Cheap Jacksonville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Jacksonville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Jacksonville to South America

Sat, May 9 - Tue, May 12
American Airlines Logo
6:00 am - 2:04 pm
JAX
-
CTG
9h 04m
1 stop
American Airlines Logo
1:25 pm - 9:15 pm
CTG
-
JAX
6h 50m
1 stop
$313American Airlines
Sat, May 9 - Tue, May 12
American Airlines Logo
8:19 pm - 2:04 pm
JAX
-
CTG
18h 45m
2 stops
American Airlines Logo
1:25 pm - 9:03 am
CTG
-
JAX
18h 38m
2 stops
$318American Airlines
Thu, Apr 9 - Thu, Apr 16
United Airlines Logo
6:35 am - 9:10 pm
JAX
-
MDE
15h 35m
1 stop
United Airlines Logo
9:45 am - 8:02 pm
MDE
-
JAX
33h 17m
3 stops
$342United Airlines
Thu, Apr 9 - Thu, Apr 16
United Airlines Logo
8:00 am - 9:10 pm
JAX
-
MDE
38h 10m
2 stops
United Airlines Logo
9:45 am - 8:02 pm
MDE
-
JAX
33h 17m
3 stops
$345United Airlines
Tue, Apr 28 - Wed, May 6
Multiple Airlines Logo
11:34 am - 6:35 am
JAX
-
UIO
20h 01m
1 stop
Multiple Airlines Logo
5:25 pm - 10:16 am
UIO
-
JAX
15h 51m
1 stop
$403Multiple Airlines
Tue, Apr 21 - Tue, May 5
Multiple Airlines Logo
11:12 am - 11:40 pm
JAX
-
UIO
13h 28m
2 stops
Multiple Airlines Logo
5:25 pm - 10:16 am
UIO
-
JAX
15h 51m
1 stop
$421Multiple Airlines
Mon, Mar 23 - Sat, Mar 28
LATAM Airlines Logo
6:30 am - 1:15 pm
JAX
-
CTG
7h 45m
1 stop
LATAM Airlines Logo
9:12 am - 9:39 am
CTG
-
JAX
23h 27m
2 stops
$426LATAM Airlines
Tue, May 12 - Tue, May 19
Delta Logo
8:05 am - 5:50 pm
JAX
-
BOG
10h 45m
2 stops
Delta Logo
11:00 am - 10:26 pm
BOG
-
JAX
10h 26m
2 stops
$515Delta
Mon, Apr 13 - Wed, Apr 22
LATAM Airlines Logo
7:59 pm - 5:00 am
JAX
-
LIM
10h 01m
1 stop
LATAM Airlines Logo
12:05 pm - 11:59 pm
LIM
-
JAX
10h 54m
1 stop
$567LATAM Airlines
Tue, May 5 - Thu, May 14
Delta Logo
11:27 am - 5:00 am
JAX
-
LIM
18h 33m
1 stop
Delta Logo
8:55 am - 12:23 am
LIM
-
JAX
14h 28m
2 stops
$615Delta
Booking Insights

KAYAK's insights & trends for Jacksonville to South America flights

Get data-powered insights and trends into flights from Jacksonville to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Jacksonville to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Jacksonville to South America is September, when tickets cost $608 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $798 and $782 respectively.

How far in advance should I book a flight from Jacksonville to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Jacksonville to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Jacksonville to South America, you should book around 6 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$130
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Jacksonville to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Jacksonville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Jacksonville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Jacksonville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Jacksonville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Jacksonville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Jacksonville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Jacksonville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Jacksonville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Jacksonville to South America

 
Need help choosing which airline to fly with from Jacksonville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8242 reviews
7.9Comfort
8.1Boarding
7.8Entertainment
7.2Food
8.5Crew
Airline reviews

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

10.0 ExcellentBob, Feb 2026
FLL - MSP
Read more Delta reviews

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

The flight was great as well as the airline staff

Comfort seating was on the tight side. Maybe it was a smaller plane(?)

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

No WiFi. Comfort plus should have alcohol provided, crew only offered water or tea. Who the heck wants tea?

I have diamond medallion status and usually we are in comfort plus . We were in main this time ( which was fine ) and my husband wanted wine . I have at least 10 vouchers for drinks that are good for this year and next! The attendant would not take the picture of the voucher as proof and never came back to check as She asked me to pull it up on delta Wi-Fi. Instead my husband just used his Amex to buy the wine . Disappointing!!!

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Good check in process Poor information on payments at Lima airport

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

For my arriving destination, we were delayed multiple times to the point that we arrived 6 hours after we were originally scheduled. On my flight home, they overbooked and involuntarily removed passengers (including me) from the plane. It was not a good experience.

Boarding is always an ordeal. Less dogs on flights. I am highly allergic to dogs and cats. Why are there so many animals these days?

Horrible. Got delayed many hours because their pilot wasn't trained for night landing at the airport and a rain delay made it a night landing. We have to wait hours for a qualified crew. They give us 12 dollar meal vouchers but most everything in the airport was closed and definitely more expensive than the vouchers.

I am an AA flyer for a very long time... AA has yet to disappoint.

Everything was good. Flight was very full so crew was busy. After we boarded and plane pulled away from the gate, we were delayed about 40 minutes- sitting on the runway - due to weather en route or at the destination. While weather is not the fault of the airline- it’s terrible to sit on a plane and not moving.

The smell from the bathroom kept wafting through the cabin. It made people sick.

Waited for oxygen tanks for 30 minutes after boarding was complete.

Awful. Original flight was delayed 5 hours. Had to to take a connecting flight instead of direct. Had a 4 hour layover. I missed all of my morning meetings getting in 5 hours later than I was supposed to and had to change to take a later flight the next day to get them back in which cia time another $150.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

Everything you need to know for your flight to South America

Information on your arrival and departure airports