EYW - SAN

$178 Find Cheap Flights from Key West to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Key West to San Diego departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Key West to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Key West to San Diego, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Key West to San Diego (EYW-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Key West to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Key West to San Diego

Tue, Sep 30 - Sat, Oct 4
Delta Logo
2:00 pm - 6:10 pmEYW-SAN
7h 10m1 stop
Delta Logo
10:30 pm - 10:55 amSAN-EYW
9h 25m1 stop
$465Delta
Find Deal
Fri, Mar 6 - Tue, Mar 10
Delta Logo
6:00 pm - 11:11 pmEYW-SAN
8h 11m1 stop
Delta Logo
8:00 am - 7:44 pmSAN-EYW
8h 44m1 stop
$468Delta
Find Deal
Tue, Sep 30 - Sat, Oct 4
American Airlines Logo
11:25 am - 8:20 pmEYW-SAN
11h 55m2 stops
American Airlines Logo
10:32 pm - 12:05 pmSAN-EYW
10h 33m1 stop
$470American Airlines
Find Deal
Fri, Mar 6 - Tue, Mar 10
United Airlines Logo
4:53 pm - 9:53 pmEYW-SAN
8h 00m1 stop
United Airlines Logo
6:30 pm - 12:46 pmSAN-EYW
15h 16m2 stops
$474United Airlines
Find Deal
Tue, Sep 30 - Sat, Oct 4
American Airlines Logo
11:25 am - 8:20 pmEYW-SAN
11h 55m2 stops
American Airlines Logo
9:19 pm - 1:29 pmSAN-EYW
13h 10m2 stops
$475American Airlines
Find Deal
Fri, Mar 6 - Tue, Mar 10
United Airlines Logo
4:53 pm - 8:30 amEYW-SAN
18h 37m2 stops
United Airlines Logo
6:30 pm - 12:46 pmSAN-EYW
15h 16m2 stops
$513United Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 11
United Airlines Logo
4:53 pm - 9:53 pmEYW-SAN
8h 00m1 stop
United Airlines Logo
9:55 pm - 12:05 pmSAN-EYW
11h 10m1 stop
$785United Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 11
United Airlines Logo
4:53 pm - 11:44 pmEYW-SAN
9h 51m2 stops
United Airlines Logo
9:55 pm - 12:05 pmSAN-EYW
11h 10m1 stop
$790United Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 11
United Airlines Logo
4:53 pm - 11:44 pmEYW-SAN
9h 51m2 stops
United Airlines Logo
6:30 pm - 12:46 pmSAN-EYW
15h 16m2 stops
$841United Airlines
Find Deal
Tue, Sep 30 - Sat, Oct 4
Breeze Airways Logo
9:47 am - 12:36 pmEYW-SAN
53h 49m2 stops
Breeze Airways Logo
1:12 pm - 10:31 amSAN-EYW
42h 19m3 stops
$972Breeze Airways
Find Deal

Everything you should know

Top airlines
Delta
Cheapest • from $465 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$465
Delta
Tue 9/30Sat 10/4
EYW - SAN • 1 stop
Cheapest one-way
$178
Typical prices: $329-538
Multiple Airlines
Wed 10/15
EYW - SAN • 2 stops
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Diego!
Booking Insights

KAYAK's insights & trends for Key West to San Diego flights

Get data-powered insights and trends into flights from Key West to San Diego to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Key West to San Diego?

The average price of all round-trip flights from Key West to San Diego clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to San Diego on a Friday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Key West to San Diego. For your return ticket, we recommend flying on a Wednesday and avoiding Thursdays for the best deals.

Good to know

Cheapest flight$178
Flight from Key West to San Diego

When to book flights from Key West to San Diego

Are your dates flexible? Find out the best times to travel from Key West to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Key West to San Diego

  • What is the cheapest flight from Key West to San Diego?

    In the last 3 days, the lowest price for a flight from Key West to San Diego was $178 for a one-way ticket and $465 for a round-trip.

  • Do I need a passport to fly between Key West and San Diego?

    No

  • Which aircraft models fly most regularly from Key West to San Diego?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Key West to San Diego?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Key West and San Diego, with SkyTeam being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Key West to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Key West to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Key West to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Key West is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Key West to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Key West with another airline. Booking your flights between Key West and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Key West to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Key West up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Key West to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Key West to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Key West to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
7.5Boarding
8.0Crew
6.4Food
7.2Comfort
6.9Entertainment
Airline reviews

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

10.0 ExcellentEnchantress, Sep 2025JFK - SFO
Read more American Airlines reviews

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

There is no room, no gluten free options, or any free internet/entertainment. You have to bring your own tablet or smartphone because there are no screens.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Everything you need to know for your flight from Key West to San Diego

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