EYW - SFO

$211 Find Cheap Flights from Key West to San Francisco - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Key West to San Francisco departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$369
Delta
Thu 8/20Mon 8/24
EYW - SFO • 1 stop
Cheapest one-way
$211
Typical prices: $400-$608
Multiple Airlines
Wed 7/15
EYW - SFO • 2 stops
Top airlines
Delta
Cheapest • from $369 (round-trip)
American Airlines
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Key West and San Francisco. You'll need at least 1 connection.
Insights
Insights
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Insights
Top layover airports
Dallas (DFW)
Cheapest • Avg $348 (round-trip)
Dallas (DFW)
Shortest trip • 8h 02m (one-way)
Insights
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We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Key West to San Francisco (EYW-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Key West to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Key West to San Francisco

Thu, Aug 20 - Mon, Aug 24
Delta Logo
1:59 pm - 10:00 pm
EYW
-
SFO
11h 01m
1 stop
Delta Logo
10:00 pm - 10:50 am
SFO
-
EYW
9h 50m
1 stop
$369Delta
Wed, Jul 15 - Sun, Jul 19
American Airlines Logo
2:21 pm - 7:39 pm
EYW
-
SFO
8h 18m
1 stop
American Airlines Logo
11:49 pm - 10:55 am
SFO
-
EYW
8h 06m
1 stop
$420American Airlines
Tue, Jul 14 - Sat, Jul 18
American Airlines Logo
11:28 am - 7:28 pm
EYW
-
SFO
11h 00m
2 stops
American Airlines Logo
7:20 am - 7:23 pm
SFO
-
EYW
9h 03m
1 stop
$428American Airlines
Wed, Jul 15 - Sun, Jul 19
American Airlines Logo
2:21 pm - 10:14 pm
EYW
-
SFO
10h 53m
2 stops
American Airlines Logo
11:49 pm - 12:14 pm
SFO
-
EYW
9h 25m
1 stop
$457American Airlines
Thu, Aug 20 - Mon, Aug 24
American Airlines Logo
1:41 pm - 10:20 pm
EYW
-
SFO
11h 39m
2 stops
American Airlines Logo
5:05 am - 4:18 pm
SFO
-
EYW
8h 13m
1 stop
$522American Airlines
Tue, Jul 14 - Sat, Jul 18
American Airlines Logo
11:28 am - 7:28 pm
EYW
-
SFO
11h 00m
2 stops
American Airlines Logo
8:11 pm - 10:55 am
SFO
-
EYW
11h 44m
2 stops
$529American Airlines
Tue, Jul 14 - Sat, Jul 18
American Airlines Logo
4:41 pm - 10:48 pm
EYW
-
SFO
9h 07m
1 stop
American Airlines Logo
11:49 pm - 12:14 pm
SFO
-
EYW
9h 25m
1 stop
$535American Airlines
Wed, Jul 15 - Sun, Jul 19
United Airlines Logo
4:00 pm - 12:32 am
EYW
-
SFO
11h 32m
1 stop
United Airlines Logo
10:35 pm - 1:30 pm
SFO
-
EYW
11h 55m
1 stop
$584United Airlines
Wed, Jul 15 - Sun, Jul 19
American Airlines Logo
2:21 pm - 10:14 pm
EYW
-
SFO
10h 53m
2 stops
American Airlines Logo
5:50 am - 7:06 pm
SFO
-
EYW
10h 16m
2 stops
$632American Airlines
Mon, Nov 2 - Fri, Nov 6
American Airlines Logo
1:23 pm - 11:59 pm
EYW
-
SFO
13h 36m
1 stop
American Airlines Logo
5:27 pm - 12:51 pm
SFO
-
EYW
16h 24m
1 stop
$669American Airlines
Booking Insights

KAYAK's insights & trends for Key West to San Francisco flights

Get data-powered insights and trends into flights from Key West to San Francisco to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Key West to San Francisco?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Key West to San Francisco were found on Delta ($369) and American Airlines ($420).

Find deals

Good to know

Cheapest flight$211
Flight from Key West to San Francisco

When to book flights from Key West to San Francisco

Are your dates flexible? Find out the best times to travel from Key West to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Key West to San Francisco

  • What is the cheapest flight from Key West to San Francisco?

    In the last 5 days, the lowest price for a flight from Key West to San Francisco was $211 for a one-way ticket and $369 for a round-trip.

  • Do I need a passport to fly between Key West and San Francisco?

    No

  • Which aircraft models fly most regularly from Key West to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Key West to San Francisco?

    oneworld is the only airline alliance operating flights between Key West and San Francisco.

  • How does KAYAK find such low prices on flights from Key West to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Key West to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Key West to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Key West is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Key West to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Key West with another airline. Booking your flights between Key West and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Key West to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Key West up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Key West to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Key West to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Key West to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11764 reviews
7.5Boarding
6.8Entertainment
7.9Crew
6.4Food
7.2Comfort
Airline reviews

The flight attendant was very polite and attentive. The food was good.

10.0 ExcellentAnonymous, Jun 2026
JFK - SFO
Read more American Airlines reviews

The flight attendant was very polite and attentive. The food was good.

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Long 5 hour and 45 min flight and only one drink service and cookie snack

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

Plane felt so crowded and tightly packed. The chair itself was not comfortable.

Everything you need to know for your flight from Key West to San Francisco

Information on your arrival and departure airports

Key West (EYW)
San Francisco (SFO)