TYS - CHI

$100 Find Cheap Flights from Knoxville to Chicago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Chicago departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Chicago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Chicago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Chicago, as well as popular online travel agencies
Travelers love KAYAK
41.299.237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$189
Overall average: $244
United Airlines
Fri 2/20Mon 2/23
TYS - ORD • Non-stop
Cheapest one-way
$100
Typical prices: $145-$360
Multiple Airlines
Tue 3/17
TYS - ORD • 1 stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
United's Economy Plus offers extra legroom on this route.
Allegiant's Legroom+ provides more space and faster exit.
Expert advice
Expert advice
Expert advice
Expert advice
Video guide: How to find cheap flights to Chicago
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Top airlines
United Airlines
Cheapest • from $189 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top routes
TYS
-
MDW
Cheapest • 18% average savings
TYS
-
ORD
Most popular
Insights
Insights
Insights
Insights
When to book
4 weeks
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 25% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
February
Cheapest • 17% price drop
May
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Chicago!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Knoxville to Chicago (TYS-CHI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Chicago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Chicago

Fri, Feb 20 - Mon, Feb 23
United Airlines Logo
6:45 am - 7:47 am
TYS
-
ORD
2h 02mnonstop
United Airlines Logo
7:35 am - 10:19 am
ORD
-
TYS
1h 44mnonstop
$189United Airlines
Fri, Feb 13 - Tue, Feb 17
United Airlines Logo
6:45 am - 7:47 am
TYS
-
ORD
2h 02mnonstop
United Airlines Logo
6:00 pm - 8:37 pm
ORD
-
TYS
1h 37mnonstop
$204United Airlines
Thu, Feb 26 - Mon, Mar 2
Delta Logo
1:00 pm - 5:37 pm
TYS
-
MDW
5h 37m
1 stop
Delta Logo
10:49 am - 3:15 pm
MDW
-
TYS
3h 26m
1 stop
$209Delta
Fri, Feb 20 - Sun, Feb 22
Delta Logo
6:41 pm - 11:56 pm
TYS
-
ORD
6h 15m
1 stop
Delta Logo
5:25 am - 11:08 am
ORD
-
TYS
4h 43m
1 stop
$209Delta
Thu, Feb 26 - Sat, Feb 28
Multiple Airlines Logo
7:00 am - 7:37 pm
TYS
-
ORD
13h 37m
1 stop
Multiple Airlines Logo
4:42 pm - 10:07 pm
ORD
-
TYS
28h 25m
2 stops
$211Multiple Airlines
Mon, Mar 30 - Wed, Apr 8
Southwest Logo
7:25 pm - 12:05 am
TYS
-
MDW
5h 40m
1 stop
Southwest Logo
12:50 pm - 8:50 pm
MDW
-
TYS
7h 00m
2 stops
$214Southwest
Mon, Feb 23 - Mon, Mar 2
Multiple Airlines Logo
7:22 pm - 4:52 pm
TYS
-
ORD
22h 30m
2 stops
Multiple Airlines Logo
10:19 am - 11:36 pm
ORD
-
TYS
12h 17m
1 stop
$216Multiple Airlines
Thu, Feb 26 - Sat, Feb 28
Multiple Airlines Logo
7:00 am - 7:37 pm
TYS
-
ORD
13h 37m
1 stop
Multiple Airlines Logo
4:42 pm - 10:07 pm
ORD
-
TYS
28h 25m
2 stops
$217Multiple Airlines
Wed, Feb 11 - Sun, Feb 15
United Airlines Logo
1:59 pm - 2:55 pm
TYS
-
ORD
1h 56mnonstop
United Airlines Logo
7:35 am - 10:19 am
ORD
-
TYS
1h 44mnonstop
$219United Airlines
Wed, Apr 15 - Sun, Apr 19
Southwest Logo
12:50 pm - 5:30 pm
TYS
-
MDW
5h 40m
1 stop
Southwest Logo
5:00 am - 2:05 pm
MDW
-
TYS
8h 05m
1 stop
$263Southwest
Booking Insights

KAYAK's insights & trends for Knoxville to Chicago flights

Get data-powered insights and trends into flights from Knoxville to Chicago to help you find the cheapest flights, the best time to fly and much more.

Find cheap flights to Chicago
Find cheap flights to Chicago

Planning a trip from Knoxville to Chicago? KAYAK’s data-powered insights will help you find cheap flights. Learn the best time to fly, how early to book your ticket, and other tips to secure great prices.

What is the cheapest Knoxville to Chicago flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest return flight from Knoxville to Chicago costs $129 on the route between Knoxville (TYS) and Chicago Midway Airport (MDW). Over the past month, this route was, on average, 18% cheaper than other Knoxville-Chicago routes. The most popular route is between Knoxville (TYS) and Chicago O'Hare Intl Airport (ORD).

What’s the cheapest day of the week to fly from Knoxville to Chicago?

The average price of all round-trip flights from Knoxville to Chicago clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Chicago on a Friday and more expensive on a Sunday. On your return trip to Knoxville, you should consider flying back on a Saturday, and avoid Fridays for better deals.

What is the cheapest month to fly from Knoxville to Chicago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Chicago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Chicago is February, where tickets cost $214 (return) on average. On the other hand, the most expensive months are July and March, where the average cost of round-trip tickets is $335 and $284 respectively.

Can I save money by flying with a layover from Knoxville to Chicago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $201, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Knoxville to Chicago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Knoxville to Chicago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Knoxville to Chicago, you should book around 4 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Expert advice

Expert advice for your flight from Knoxville to Chicago

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Harriet Baskas

Harriet Baskas

Expert on American Airlines

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Daniel Scheffler

Daniel Scheffler

Expert on Allegiant Air

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Good to know

Low seasonJune
Cheapest flight$100
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Knoxville to Chicago O'Hare Airport

When to book flights from Knoxville to Chicago

Are your dates flexible? Find out the best times to travel from Knoxville to Chicago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Chicago

  • What parking options are available at the Knoxville McGhee Tyson Airport?

    Knoxville's McGhee Tyson Airport (TYS) offers both short-term and long-term parking options. Short-term parking is available in the hourly lot and can be used for up to 24 hours. This lot is located near the terminal building and features direct access to the terminal via an elevated walkway. Long-term parking is also available at McGhee Tyson Airport and can be used for up to 30 days. The long-term parking lot is located on the east side of the airport. There's valet parking available for those who would like to have their car parked for them while they're traveling.

  • Can I get a rental car at Chicago O'Hare International Airport (ORD)?

    You can choose from a number of car-rental companies, including National, Avis, Enterprise, Hertz, Budget Dollar, and Alamo. If you're looking for a great deal on a rental car, Hertz is the way to go. Hertz has convenient locations at Chicago O'Hare International Airport (ORD). And if you're looking for some extra room or luxury while traveling, then National Car Rental is the way to go. National Car Rental has convenient locations at Chicago O'Hare International Airport (ORD).

  • What check-in options do I have for my flight from Knoxville to Chicago?

    Frontier Airlines requires you to check in online up to 60 minutes before your departure. For the physical check-in at the airport, you should arrive at the airport at least two hours before departure and have your boarding pass printed and validated.

  • Are there kid-friendly facilities at the Knoxville McGhee Tyson Airport?

    If you're traveling through Knoxville's McGhee Tyson Airport, you may be wondering where you can nurse your baby. The McGhee Tyson Airport provides a Mamava pod past the food-concession area. This nursing room is equipped with an electric breast pump, changing table, private sink, and electrical outlets to facilitate electrical breast pumps.

  • What is the cheapest flight from Knoxville to Chicago?

    In the last 3 days, the lowest price for a flight from Knoxville to Chicago was $100 for a one-way ticket and $189 for a round-trip.

  • Do I need a passport to fly between Knoxville and Chicago?

    No

  • Which airports will I be using when flying from Knoxville to Chicago?

    Knoxville is served by only 1 airport and there are 2 airports in Chicago. You will leave Knoxville from Knoxville McGhee Tyson and you will be arriving in Chicago at one of these airports: Chicago Midway or Chicago O'Hare Intl.

  • Which airlines offer Wi-Fi service onboard planes from Knoxville to Chicago?

    American Airlines, and Delta offer inflight Wi-Fi service on the Knoxville to Chicago flight route.

  • Which aircraft models fly most regularly from Knoxville to Chicago?

    The Canadair (Bombardier) Regional Jet 700 is the aircraft model that flies most regularly on the Knoxville to Chicago flight route.

  • Which airline alliances offer flights from Knoxville to Chicago?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Knoxville and Chicago, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Knoxville to Chicago?

    There are nonstop flights from Knoxville to Chicago on a daily basis.

  • Which is the best airline for flights from Knoxville to Chicago, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Chicago are United Airlines and American Airlines. With an average price for the route of $290 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $260 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Knoxville to Chicago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Chicago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Chicago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Chicago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to Knoxville with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Chicago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Knoxville to Chicago

  • Looking for a cheap flight? 25% of our users found flights on this route for $204 or less one-way and $346 or less round-trip.
  • If you love to travel, the Delta Air Lines companion ticket could be a dream come true. You’ll get to take your friend or family member along with you on your next trip. With American Express, there are two individual Delta credit cards that include a companion certificate.
  • If you're looking for a place to relax, unwind, and take your mind off of the hustle and bustle of air travel, look no further than the USO Lounge at Chicago Midway Airport (MDW). Located in the center of Concourse C, this lounge is open to military personnel, veterans, and their families. All guests are welcome to enjoy free Wi-Fi, snacks and drinks, TVs with cable, and a children's play area.
  • Finnair provides passengers with a nice variety of in-flight entertainment options, allowing you to choose from a wide range of movies and TV shows. The entertainment system offers several audio channels, including news, music, and sports channels. There are also several games available for you to play while you're onboard Finnair flights.
  • McGhee Tyson Airport (TYS) offers services for people with disabilities to make their trip as easy as possible. They have handicap parking spaces, restrooms, and seating areas, as well as wheelchair-accessible ramps and elevators in the terminal building.
  • Bensenville, Schiller Park, Franklin Park, and Wood Dale are all suburbs of Chicago near the Chicago O'Hare International Airport (ORD). To get to the suburbs, you can take the Blue Line train.

Prefer to fly direct from Knoxville to Chicago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Knoxville McGhee Tyson to Chicago.
Find which airlines fly direct from Knoxville McGhee Tyson Airport to Chicago, which days they fly and book direct flights.

Direct departures

Knoxville McGhee Tyson to Chicago

Monday

American Airlines, United Airlines

American Airlines, United Airlines

Tuesday

American Airlines, United Airlines

American Airlines, United Airlines

Wednesday

American Airlines, United Airlines

American Airlines, United Airlines

Thursday

American Airlines, United Airlines

American Airlines, United Airlines

Friday

American Airlines, United Airlines

American Airlines, United Airlines

Saturday

American Airlines, United Airlines

American Airlines, United Airlines

Sunday

American Airlines, United Airlines

American Airlines, United Airlines

See more direct flights

Direct returns

Chicago to Knoxville McGhee Tyson

Monday

American Airlines, United Airlines

American Airlines, United Airlines

Tuesday

American Airlines, United Airlines

American Airlines, United Airlines

Wednesday

American Airlines, United Airlines

American Airlines, United Airlines

Thursday

American Airlines, United Airlines

American Airlines, United Airlines

Friday

American Airlines, United Airlines

American Airlines, United Airlines

Saturday

American Airlines, United Airlines

American Airlines, United Airlines

Sunday

American Airlines, United Airlines

American Airlines, United Airlines

See more direct flights

Reviews of the top 3 airlines serving from Knoxville to Chicago

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Chicago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Chicago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9205 reviews
7.7Boarding
8.1Crew
6.6Food
7.3Comfort
7.1Entertainment
Airline reviews

Seated dude next to me even though lots of empty rows. But main thing was we sat on the tarmac after landing for 30 minutes because of, in the words of the dude who sat next to me, “operational incompetence”. We got changing directions about where to pick up gate checked bags. Pilot and flight attendant were awesome though.

4.0 OkaySean, Jan 2026
BOS - ORD
Read more United Airlines reviews

Seated dude next to me even though lots of empty rows. But main thing was we sat on the tarmac after landing for 30 minutes because of, in the words of the dude who sat next to me, “operational incompetence”. We got changing directions about where to pick up gate checked bags. Pilot and flight attendant were awesome though.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

Perfect flight. Smooth flight. Arrived 20 minutes early at destination. Excellent service.

The flights were on time which was great give. It was holiday travel season and there’d been some weather issues. The only complaint and this is every time with United is the terrible seat design. The head rest is not built for comfort and having my neck bent forward for a cross country trip reminded me while I try not to take United flights as a rule.

Everything was absolutely wonderful from check in to baggage claim. Staff was very professional and sweet. Will definitely recommend United to family and friends.

They did the one thing that really matters - got to Chicago early.

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

Very bad! They kept delaying my flight and wouldn’t do anything about it

Door to door, the crew and staff were amazing. It was a stressful travel day with delays, but they were focused on customers and doing what they could to get us to our destinations.

Pilot navigated severe weather/snow storm with skill. Described his intentions clearly

Little warm on the plane and delayed for an hour

So excited very proud first of all I wanna thank kayak all updates very professional and fast alart And amazing cabin crew so nice to me they deserve big salute

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

I enjoyed the extra leg room compared to other airlines. The first stewards made my daughter’s birthday special by giving her an extra snack. Then the last one coming home from Chicago to Appleton made our night really enjoyable Thanks for making our trip enjoyable

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

It was good..clean, comfy seat. Friendly warm welcoming crew. Was able to check my cabin luggage at the gate which I was able to pickup in a decent time from baggage claim. The app gave all updates from delays to baggage claim info. Overall smooth flight.

It was a typical flight. We had a delay which seems to be the normality now. And we had no in flight service due to conditions.

It was fine. Nobody was outstandingly friendly but no one was rude and everything was smooth . The captain thanked us for flying but no one greeted me as I walked on the plane or as I exited which is the least they could do lol

Clean, friendly, roomy. But check-in from the phone link was terrible. Repeated attempts wouldn’t save at the final step. Just kept spinning! It was very frustrating. Finally, I used the app (vs website link) to check-in which worked very smoothly on the first attempt.

Check in on the web portal was cumbersome! After several attempts I finally got the boarding pass.

Excellent flight and even arrived 23 min early. No entertainment , or wi fi on board, but I downloaded a couple of movies beforehand which kept me entertained. Really like flying Allegiant airlines.

WE were delayed about an hour and never any communications from the employees working the gate. We also were moved to a total of three gates.

I love how they show love to their customers and care about them too.

I liked how when I got on board how fast we ended up taking off but what I truly disliked was how uncomfortable the seats were. There was truly never a time that I could ever get comfortable during both of my flights. The seats could get away during shorter flights but flights 3 hour plus makes it hard to enjoy.

The crew was great and the flight was very smooth. Can’t really judge food since I did not get any because it costs money. The seat was comfortable for what we bought. Thanks!

Crew was great. No entertainment and food and beverage was for purchase only, even water

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

Everything you need to know for your flight from Knoxville to Chicago

Information on your arrival and departure airports