TYS - CHI

$55 Find Cheap Flights from Knoxville to Chicago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Chicago departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Chicago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Chicago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Chicago, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$176
Overall average: $211
Multiple Airlines
Fri 11/14Sun 11/16
TYS - MDW • Non-stop
Cheapest non-stop
$189
Typical prices: $219-$418
American Airlines
Fri 12/12Thu 1/15
TYS - ORD • Non-stop
Our travelers' advice
AI-generated summary based on content written by travel experts
United's Economy Plus offers extra legroom on this route.
Allegiant's Legroom+ provides more space and faster exit.
Expert advice
Expert advice
Expert advice
Expert advice
Video guide: How to find cheap flights to Chicago
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Top airlines
American Airlines
Cheapest • from $189 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top routes
TYS-MDW
Cheapest • 41% average savings
TYS-ORD
Most popular
Insights
Insights
Insights
Insights
When to book
4 weeks
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 33% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
February
Cheapest • 21% price drop
November
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Chicago!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Knoxville to Chicago (TYS-CHI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Chicago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Chicago

Fri, Nov 14 - Sun, Nov 16
Multiple Airlines Logo
2:02 pm - 2:37 pmTYS-MDW
1h 35mnonstop
Multiple Airlines Logo
6:06 pm - 8:29 pmMDW-TYS
25h 23m1 stop
$176Multiple Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
Multiple Airlines Logo
9:00 am - 10:10 pmTYS-MDW
14h 10m1 stop
Multiple Airlines Logo
4:12 pm - 6:37 pmMDW-TYS
1h 25mnonstop
$185Multiple Airlines
Find Deal
Fri, Dec 12 - Thu, Jan 15
American Airlines Logo
6:29 pm - 7:33 pmTYS-ORD
2h 04mnonstop
American Airlines Logo
7:29 pm - 10:09 pmORD-TYS
1h 40mnonstop
$189American Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
American Airlines Logo
6:16 pm - 7:20 pmTYS-ORD
2h 04mnonstop
American Airlines Logo
3:01 pm - 5:46 pmORD-TYS
1h 45mnonstop
$199American Airlines
Find Deal
Fri, Dec 12 - Sun, Dec 14
Delta Logo
7:59 pm - 11:47 pmTYS-MDW
4h 48m1 stop
Delta Logo
5:13 pm - 11:28 pmMDW-TYS
5h 15m1 stop
$209Delta
Find Deal
Fri, Dec 12 - Sun, Dec 14
Delta Logo
7:59 pm - 12:01 amTYS-ORD
5h 02m1 stop
Delta Logo
6:45 am - 11:47 amORD-TYS
4h 02m1 stop
$209Delta
Find Deal
Fri, Nov 14 - Sun, Nov 16
United Airlines Logo
5:52 pm - 6:53 pmTYS-ORD
2h 01mnonstop
United Airlines Logo
5:50 pm - 8:33 pmORD-TYS
1h 43mnonstop
$219United Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
Allegiant Air Logo
12:45 pm - 1:21 pmTYS-MDW
1h 36mnonstop
Allegiant Air Logo
7:36 pm - 12:16 pmMDW-TYS
39h 40m2 stops
$243Allegiant Air
Find Deal
Sat, Dec 6 - Mon, Dec 15
United Airlines Logo
7:00 am - 8:01 amTYS-ORD
2h 01mnonstop
United Airlines Logo
7:30 am - 10:13 amORD-TYS
1h 43mnonstop
$249United Airlines
Find Deal
Wed, Nov 26 - Sun, Nov 30
Allegiant Air Logo
6:18 pm - 6:54 pmTYS-MDW
1h 36mnonstop
Allegiant Air Logo
4:24 pm - 6:49 pmMDW-TYS
1h 25mnonstop
$293Allegiant Air
Find Deal
Booking Insights

KAYAK's insights & trends for Knoxville to Chicago flights

Get data-powered insights and trends into flights from Knoxville to Chicago to help you find the cheapest flights, the best time to fly and much more.

Find cheap flights to Chicago
Find cheap flights to Chicago

Planning a trip from Knoxville to Chicago? KAYAK’s data-powered insights will help you find cheap flights. Learn the best time to fly, how early to book your ticket, and other tips to secure great prices.

How much is a round-trip flight from Knoxville to Chicago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Chicago departing in November.

What is the cheapest Knoxville to Chicago flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest return flight from Knoxville to Chicago costs $78 on the route between Knoxville (TYS) and Chicago Midway Airport (MDW). Over the past month, this route was, on average, 41% cheaper than other Knoxville-Chicago routes. The most popular route is between Knoxville (TYS) and Chicago O'Hare Intl Airport (ORD).

What’s the cheapest day of the week to fly from Knoxville to Chicago?

The average price of all round-trip flights from Knoxville to Chicago clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Chicago on a Friday and more expensive on a Monday. On your return trip to Knoxville, you should consider flying back on a Wednesday, and avoid Mondays for better deals.

What is the cheapest month to fly from Knoxville to Chicago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Chicago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Chicago is February, where tickets cost $204 (return) on average. On the other hand, the most expensive months are July and April, where the average cost of round-trip tickets is $334 and $289 respectively.

Can I save money by flying with a layover from Knoxville to Chicago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $220, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Knoxville to Chicago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Knoxville to Chicago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Knoxville to Chicago, you should book around 4 weeks before departure, which saves you about 33% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Expert advice

Expert advice for your flight from Knoxville to Chicago

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
American Airlines

Main Cabin Extra offers early boarding and complimentary alcoholic drinks.


Download the American Airlines app for inflight entertainment access.

United Airlines

United's Economy Plus offers up to 6 inches more legroom than standard economy seats.


Purchase Priority Boarding to avoid gate-checking your carry-on bag.

Allegiant Air

Allegiant's Legroom+ seating offers extra space and faster deplaning.


Use Allegiant's app for mobile boarding passes to avoid extra charges.

Our travel experts
Harriet Baskas

Harriet Baskas

Expert on American Airlines

Harriet Baskas

Harriet Baskas

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more
Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek

Stefanie Waldek

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Read more
Daniel Scheffler

Daniel Scheffler

Expert on Allegiant Air

Daniel Scheffler

Daniel Scheffler

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more

Good to know

Low seasonFebruary
Cheapest flight$55
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from Knoxville to Chicago O'Hare Airport

When to book flights from Knoxville to Chicago

Are your dates flexible? Find out the best times to travel from Knoxville to Chicago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Chicago

  • What parking options are available at the Knoxville McGhee Tyson Airport?

    Knoxville's McGhee Tyson Airport (TYS) offers both short-term and long-term parking options. Short-term parking is available in the hourly lot and can be used for up to 24 hours. This lot is located near the terminal building and features direct access to the terminal via an elevated walkway. Long-term parking is also available at McGhee Tyson Airport and can be used for up to 30 days. The long-term parking lot is located on the east side of the airport. There's valet parking available for those who would like to have their car parked for them while they're traveling.

  • Can I get a rental car at Chicago O'Hare International Airport (ORD)?

    You can choose from a number of car-rental companies, including National, Avis, Enterprise, Hertz, Budget Dollar, and Alamo. If you're looking for a great deal on a rental car, Hertz is the way to go. Hertz has convenient locations at Chicago O'Hare International Airport (ORD). And if you're looking for some extra room or luxury while traveling, then National Car Rental is the way to go. National Car Rental has convenient locations at Chicago O'Hare International Airport (ORD).

  • What check-in options do I have for my flight from Knoxville to Chicago?

    Frontier Airlines requires you to check in online up to 60 minutes before your departure. For the physical check-in at the airport, you should arrive at the airport at least two hours before departure and have your boarding pass printed and validated.

  • Are there kid-friendly facilities at the Knoxville McGhee Tyson Airport?

    If you're traveling through Knoxville's McGhee Tyson Airport, you may be wondering where you can nurse your baby. The McGhee Tyson Airport provides a Mamava pod past the food-concession area. This nursing room is equipped with an electric breast pump, changing table, private sink, and electrical outlets to facilitate electrical breast pumps.

  • What is the cheapest flight from Knoxville to Chicago?

    In the last 3 days, the lowest price for a flight from Knoxville to Chicago was $55 for a one-way ticket and $176 for a round-trip.

  • Do I need a passport to fly between Knoxville and Chicago?

    No

  • Which airports will I be using when flying from Knoxville to Chicago?

    Knoxville is served by only 1 airport and there are 2 airports in Chicago. You will leave Knoxville from Knoxville McGhee Tyson and you will be arriving in Chicago at one of these airports: Chicago Midway or Chicago O'Hare Intl.

  • Which airlines offer Wi-Fi service onboard planes from Knoxville to Chicago?

    American Airlines, and Delta offer inflight Wi-Fi service on the Knoxville to Chicago flight route.

  • Which aircraft models fly most regularly from Knoxville to Chicago?

    The Canadair (Bombardier) Regional Jet 700 is the aircraft model that flies most regularly on the Knoxville to Chicago flight route.

  • Which airline alliances offer flights from Knoxville to Chicago?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Knoxville and Chicago, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Knoxville to Chicago?

    There are nonstop flights from Knoxville to Chicago on a daily basis.

  • Which is the best airline for flights from Knoxville to Chicago, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Chicago are United Airlines and American Airlines. With an average price for the route of $299 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $257 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Knoxville to Chicago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Chicago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Chicago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Chicago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to Knoxville with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Chicago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Knoxville to Chicago

  • Looking for a cheap flight? 25% of our users found flights on this route for $173 or less one-way and $210 or less round-trip.
  • If you love to travel, the Delta Air Lines companion ticket could be a dream come true. You’ll get to take your friend or family member along with you on your next trip. With American Express, there are two individual Delta credit cards that include a companion certificate.
  • If you're looking for a place to relax, unwind, and take your mind off of the hustle and bustle of air travel, look no further than the USO Lounge at Chicago Midway Airport (MDW). Located in the center of Concourse C, this lounge is open to military personnel, veterans, and their families. All guests are welcome to enjoy free Wi-Fi, snacks and drinks, TVs with cable, and a children's play area.
  • Finnair provides passengers with a nice variety of in-flight entertainment options, allowing you to choose from a wide range of movies and TV shows. The entertainment system offers several audio channels, including news, music, and sports channels. There are also several games available for you to play while you're onboard Finnair flights.
  • McGhee Tyson Airport (TYS) offers services for people with disabilities to make their trip as easy as possible. They have handicap parking spaces, restrooms, and seating areas, as well as wheelchair-accessible ramps and elevators in the terminal building.
  • Bensenville, Schiller Park, Franklin Park, and Wood Dale are all suburbs of Chicago near the Chicago O'Hare International Airport (ORD). To get to the suburbs, you can take the Blue Line train.

Prefer to fly direct from Knoxville to Chicago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Knoxville McGhee Tyson to Chicago.
Find which airlines fly direct from Knoxville McGhee Tyson Airport to Chicago, which days they fly and book direct flights.

Direct departures

Knoxville McGhee Tyson to Chicago

Monday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Tuesday

American Airlines, United Airlines

American Airlines, United Airlines

Wednesday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Thursday

American Airlines, United Airlines

American Airlines, United Airlines

Friday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Saturday

American Airlines, United Airlines

American Airlines, United Airlines

Sunday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

See more direct flights

Direct returns

Chicago to Knoxville McGhee Tyson

Monday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Tuesday

American Airlines, United Airlines

American Airlines, United Airlines

Wednesday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Thursday

American Airlines, United Airlines

American Airlines, United Airlines

Friday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Saturday

American Airlines, United Airlines

American Airlines, United Airlines

Sunday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

See more direct flights

Reviews of the top 3 airlines serving from Knoxville to Chicago

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Chicago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Chicago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 8998 reviews
7.7Boarding
7.3Comfort
8.1Crew
7.1Entertainment
6.6Food
Airline reviews

Flight was delayed only slightly before takeoff due to traffic control. However, the flight arrived early to ORD. Good flight. United has been very reliable for me.

10.0 ExcellentDr. Joseph, Oct 2025STL - ORD
Read more United Airlines reviews

Flight was delayed only slightly before takeoff due to traffic control. However, the flight arrived early to ORD. Good flight. United has been very reliable for me.

Another delayed flight. When the delays exceed the duration of the flight, it’s a problem.

After boarding the plane in Chicago, the passengers were told that there was a technical problem with the plane. Passengers remained on the plane as they tried to fix the problem. After what was probably an hour passengers were told that there was a need to change planes as the problem was not solved. Passengers disembarked and boarded another plane. After taxing to the runway and waiting for takeoff, passengers were told that owing to the thunderstorm the flight was unable to take off but would try and reroute. After some time passengers were told there wasn't enough fuel for the new route and the plane had to return to the gate for additional fuel. after another log delay the flight got underway. On the plane there was food, drinks, ice or entertainment. We were a glass of water, which appeared rationed. Flight arrived about 5 hours late. The pilot was fantastic and communicated with the passengers throughout the ordeal.

Better WiFi. I cannot understand that in 2025, United is so behind on a technology that is now a necessity and still painfully unreliable, slow and keeps disconnecting.

Trip was great. A wild landing in Ottawa with the wind and rain, but the pilot did a great job. Always love flying United.👍

Excellent experience. Starting with the agent at the Premier bag drop who noticed I was very early for my scheduled flight and offered to rebook me on an earlier flight with my seat preference. She would not let me leave the counter until she knew that all of the changes and new boarding pass showed up on my United app. At the gate, the flight boarded quickly such that we departed early and the flight was smooth. We arrived 20 minutes early at ORD and I was able to be home in time for dinner. One of the best flights I've had.

Salina to travers city was great! But the sept 24 Tranverse city was not! Traverse city to chichago was cancelled, i went to Denver & got to Salina 6 hours later!

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Flight attendant in first class gave poor service (like he didn't want to be there) and food was awful. We sat waiting for gate upon arrival over 45 mins.

Weather delay in Chicago?. No sense of urgency to make connection in Chicago for our connecting flight that wasn't delayed. Connection was missed.

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

It was good..clean, comfy seat. Friendly warm welcoming crew. Was able to check my cabin luggage at the gate which I was able to pickup in a decent time from baggage claim. The app gave all updates from delays to baggage claim info. Overall smooth flight.

It was a typical flight. We had a delay which seems to be the normality now. And we had no in flight service due to conditions.

After we landed we sat on the tarmac for 1.5 hours waiting to get to our gate. Ridiculous.

Terrible. Flight delayed for more than 8 hours with only a $12 meal voucher provided for the inconvenience. The airplane did not have breaks on arrival yet they still made us go through the motions and board on time knowing we could not take off then sit for 40+ minutes before having to get of the time. A complete waste of my time. I cannot believe they can stay business with these shenanigans. I’ll avoid this company like the plague moving forward as the lack of accountability is disgraceful.

This was the best 2 flights I have had with American out of SGF. Great crew both flights.

Excellent - explanations were clear staff was nice and flight was comfortable

Lost bag and 2 days no word leaving for cruise no clothes or stuff

Any flight to ORD after about 2pm this summer has been challenging. Flight was delayed getting in (coming from ORD) and that led to it not leaving before a ground stop due to lightening before they could fuel the plane, and so forth. They made up some time but we were still late in arriving at ORD, and that led to missed connections.

Food was ok, but not as good as I have had before on AA.

I liked how when I got on board how fast we ended up taking off but what I truly disliked was how uncomfortable the seats were. There was truly never a time that I could ever get comfortable during both of my flights. The seats could get away during shorter flights but flights 3 hour plus makes it hard to enjoy.

The crew was great and the flight was very smooth. Can’t really judge food since I did not get any because it costs money. The seat was comfortable for what we bought. Thanks!

Crew was great. No entertainment and food and beverage was for purchase only, even water

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

Everything you need to know for your flight from Knoxville to Chicago

Information on your arrival and departure airports

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