CHI - TYS

$49 Find Cheap Flights from Chicago to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Knoxville departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Knoxville, as well as popular online travel agencies
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Cheap Flights from Chicago to Knoxville (CHI-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Knoxville

Fri, Sep 12 - Mon, Sep 15
Allegiant Air Logo
7:50 pm - 10:21 pmMDW-TYS
1h 31mnonstop
Allegiant Air Logo
6:24 pm - 7:00 pmTYS-MDW
1h 36mnonstop
$77Allegiant Air
Find Deal
Fri, Sep 12 - Mon, Sep 15
Allegiant Air Logo
7:50 pm - 10:21 pmMDW-TYS
1h 31mnonstop
Allegiant Air Logo
6:24 pm - 7:00 pmTYS-MDW
1h 36mnonstop
$78Allegiant Air
Find Deal
Sat, Sep 6 - Sat, Sep 13
American Airlines Logo
6:14 pm - 9:00 pmORD-TYS
1h 46mnonstop
American Airlines Logo
3:10 pm - 4:10 pmTYS-ORD
2h 00mnonstop
$189American Airlines
Find Deal
Sat, Aug 16 - Thu, Aug 21
American Airlines Logo
6:29 pm - 9:13 pmORD-TYS
1h 44mnonstop
American Airlines Logo
12:56 pm - 1:49 pmTYS-ORD
1h 53mnonstop
$194American Airlines
Find Deal
Fri, Aug 15 - Tue, Aug 19
United Airlines Logo
7:52 pm - 10:37 pmORD-TYS
1h 45mnonstop
United Airlines Logo
7:00 am - 7:56 amTYS-ORD
1h 56mnonstop
$199United Airlines
Find Deal
Tue, Aug 19 - Fri, Aug 22
 Logo
8:12 pm - 10:04 amORD-TYS
12h 52m1 stop
 Logo
1:22 pm - 10:22 pmTYS-ORD
10h 00m1 stop
Sun, Aug 17 - Sat, Aug 23
United Airlines Logo
7:50 pm - 10:35 pmORD-TYS
1h 45mnonstop
United Airlines Logo
5:45 am - 9:36 amTYS-ORD
4h 51m1 stop
$204United Airlines
Find Deal
Wed, Oct 1 - Sun, Oct 5
 Logo
5:17 pm - 8:40 amORD-TYS
14h 23m1 stop
 Logo
7:20 am - 7:50 pmTYS-ORD
13h 30m1 stop
Sat, Aug 30 - Wed, Sep 3
Delta Logo
5:45 am - 10:27 amORD-TYS
3h 42m1 stop
Delta Logo
5:19 pm - 10:20 pmTYS-ORD
6h 01m1 stop
$209Delta
Find Deal
Wed, Aug 27 - Mon, Sep 8
Delta Logo
6:00 am - 10:42 amMDW-TYS
3h 42m1 stop
Delta Logo
6:14 pm - 9:26 pmTYS-MDW
4h 12m1 stop
$209Delta
Find Deal
Expert advice

Expert advice for your flight from Chicago to Knoxville

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
American Airlines

Main Cabin Extra offers early boarding and complimentary drinks for a small fee.


Basic Economy has late boarding and no free checked bags, consider Main Cabin for flexibility.

United Airlines

Economy Plus offers extra legroom with up to six inches more than standard economy.


Purchase Priority Boarding to ensure overhead bin space for carry-ons.

Allegiant Air

Choose Legroom+ for extra space and faster deplaning on select flights.


Use the Allegiant app for mobile boarding passes to avoid printing fees.

Our travel experts
Harriet Baskas

Harriet Baskas

Expert on American Airlines

Harriet Baskas

Harriet Baskas

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more
Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek

Stefanie Waldek

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Read more
Daniel Scheffler

Daniel Scheffler

Expert on Allegiant Air

Daniel Scheffler

Daniel Scheffler

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more
Booking Insights

KAYAK's insights & trends for Chicago to Knoxville flights

Get data-powered insights and trends into flights from Chicago to Knoxville to help you find the cheapest flights, the best time to fly and much more.

Find cheap flights to Knoxville
Find cheap flights to Knoxville

Planning a trip from Chicago to Knoxville? KAYAK’s data-powered insights will help you find cheap flights. Learn the best time to fly, how early to book your ticket, and other tips to secure great prices.

What is the cheapest Chicago to Knoxville flight route?

The cheapest price for flight routes found by users searching on KAYAK in the last 2 weeks for round-trip flights from Chicago to Knoxville.

Our data shows that the cheapest route for a return flight from Chicago to Knoxville cost $76 and was between Chicago Midway Airport (MDW) and Knoxville (TYS). On average, the best prices are found if you fly this route. The average price for a return flight for this route is $76.

What’s the cheapest day of the week to fly from Chicago to Knoxville?

The average price of all round-trip flights from Chicago to Knoxville clicked on KAYAK for each day over the last 12 months.

For Chicago to Knoxville, Wednesday is the cheapest day to fly on average and Friday is the most expensive. Flying from Knoxville back to Chicago, the best deals are generally found on Thursday, with Sunday being the most expensive.

What is the cheapest month to fly from Chicago to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to Knoxville is August, where tickets cost $216 (return) on average. On the other hand, the most expensive months are December and March, where the average cost of round-trip tickets is $334 and $319 respectively.

How far in advance should I book a flight from Chicago to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to Knoxville, you should book around 3 weeks before departure, which saves you about 24% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$49
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from Chicago Midway Airport to Knoxville

When to book flights from Chicago to Knoxville

Are your dates flexible? Find out the best times to travel from Chicago to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Chicago to Knoxville

  • What are the different kinds of flights that are usually available between Chicago and Knoxville?

    You can find a few different daily flights between Chicago and Knoxville that are non-stop. These flights are usually operated by Allegiant Air and American Airlines. Some flights may include a layover, and these are typically serviced by Delta Airlines. Your layover may be in a city such as Charlotte or Detroit.

  • How can I best go between central Chicago and Chicago Midway International Airport?

    The easiest and most efficient way to get from downtown Chicago to Chicago Midway International Airport is by driving. Unless there is extra traffic, the trip will normally take around 15 to 20min in total. Public transportation does not connect these two locations, so you will either need to have your own vehicle or grab a local taxi to go to the airport.

  • What type of transportation is best for going from McGhee Tyson Airport to the city center?

    The most common way of going from McGhee Tyson Airport to the city center is by driving, which will usually take around 20min in total. Public transportation does not connect these two locations, so you will either need to have your own vehicle or grab a local taxi from the airport.

  • Do I have the option of renting a vehicle directly from McGhee Tyson Airport?

    McGhee Tyson Airport has a car rental facility that is placed on the lower level of the Arrivals Terminal near the baggage claim. You will find desks for several different rental companies in this area, including Avis, Dollar, and National. All of these companies conveniently keep their fleets on airport property.

  • What is the cheapest flight from Chicago to Knoxville?

    In the last 3 days, the lowest price for a flight from Chicago to Knoxville was $49 for a one-way ticket and $77 for a round-trip.

  • Do I need a passport to fly between Chicago and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Chicago to Knoxville?

    Chicago is served by 2 major airports and there is only 1 main airport in Knoxville. You will leave Chicago from one of these airports: Chicago Midway or Chicago O'Hare Intl. You will be arriving at Knoxville McGhee Tyson.

  • Which airlines offer Wi-Fi service onboard planes from Chicago to Knoxville?

    American Airlines, and Delta offer inflight Wi-Fi service on the Chicago to Knoxville flight route.

  • Which aircraft models fly most regularly from Chicago to Knoxville?

    The Canadair (Bombardier) Regional Jet CRJ-550 is the aircraft model that flies most regularly on the Chicago to Knoxville flight route.

  • Which airline alliances offer flights from Chicago to Knoxville?

    oneworld, and Star Alliance are the airline alliances operating flights between Chicago and Knoxville, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Chicago to Knoxville?

    There are nonstop flights from Chicago to Knoxville on a daily basis.

  • Which is the best airline for flights from Chicago to Knoxville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Chicago to Knoxville are Delta and United Airlines. With an average price for the route of $243 and an overall rating of 8.0, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $306 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Chicago to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Chicago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Chicago with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Chicago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Chicago to Knoxville

  • Looking for a cheap flight? 25% of our users found flights on this route for $175 or less one-way and $160 or less round-trip.
  • Those that will be flying out of the Chicago region can choose from two different airports to depart from. There is Chicago O'Hare International Airport (ORD) which is around 17 miles from the city center and Chicago Midway International Airport (MDW) that is around 12 miles from downtown.
  • If you’ll be traveling with an infant, take note of the Mamava pods that are spread throughout McGhee Tyson Airport (TYS). These pods provide parents with a few different amenities, including comfortable seating, running water, changing tables, outlets, and plenty of room to put a stroller.
  • Travelers that will be departing early in the morning from Chicago O'Hare International Airport may find it convenient to stay directly at the airport the night before. The Hilton Chicago O’Hare Airport Hotel can be found directly across from Terminal 2 and is connected to each terminal via an underground walkway and a free shuttle service.
  • When traveling with pets, keep in mind that McGhee Tyson Airport has an animal relief area that is placed outside of the lower level of the terminal building before the Airport Hilton. This relief area has plenty of grass, as well as a sitting area and trash cans.
  • To fuel up before a long day of traveling, head to one of the many dining options in Chicago Midway International Airport. There are a few different choices spread throughout the terminals, including Dunkin Donuts, Gold Coast Dogs, and Pegasus On The Fly.

Prefer to fly direct from Chicago to Knoxville?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Chicago to Knoxville McGhee Tyson.
Find which airlines fly direct from Chicago to Knoxville McGhee Tyson Airport, which days they fly and book direct flights.

Direct departures

Chicago to Knoxville McGhee Tyson

Monday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Tuesday

American Airlines, United Airlines

American Airlines, United Airlines

Wednesday

American Airlines, United Airlines

American Airlines, United Airlines

Thursday

American Airlines, United Airlines

American Airlines, United Airlines

Friday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Saturday

American Airlines, United Airlines

American Airlines, United Airlines

Sunday

American Airlines, United Airlines

American Airlines, United Airlines

See more direct flights

Direct returns

Knoxville McGhee Tyson to Chicago

Monday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Tuesday

American Airlines, United Airlines

American Airlines, United Airlines

Wednesday

American Airlines, United Airlines

American Airlines, United Airlines

Thursday

American Airlines, United Airlines

American Airlines, United Airlines

Friday

Allegiant Air, American Airlines, United Airlines

Allegiant Air, American Airlines, +1 more

Saturday

American Airlines, United Airlines

American Airlines, United Airlines

Sunday

American Airlines, United Airlines

American Airlines, United Airlines

See more direct flights

Reviews of the top 4 airlines serving from Chicago to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Chicago to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7980 reviews
7.9Comfort
8.2Boarding
8.5Crew
7.9Entertainment
7.3Food
Airline reviews

My experience on any Delta flight is always overshadowed by the time Delta removed me from a flight for no apparent reason.

2.0 MediocreGim, Jul 2025BGM - DTW
Read more Delta reviews

My experience on any Delta flight is always overshadowed by the time Delta removed me from a flight for no apparent reason.

Delayed and took off even later than the scheduled delay time

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Great experience on Delta. Staff from baggage check to flight attendants were very courteous and professional. My only issue was a personal preference for pretzels instead of the chips and cookies that were offered.

There was no problems, just a little uncomfortable with seats that do not lay back a little

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

Flight was delayed, 30+ bags had to be gate checked. Crew were very friendly!

Everything was good until we were boarding our connection flight in Atlanta, we were told to gate check our carry-on, but when we got inside the plane, there was plenty of room in the overhead.

Did not know my son and I had different seating arrangements. He was fine, but it was disappointing.

Flight was canceled, and no effort was made to help with rebooking, no hotel vouchers, no car transportation and minimal food voucher and most places for food were closed by the time the voucher was given. Waited for 3 hours for bags. Simply the worst travel experience I have ever had

It was delayed instead of departing at 9:20pm, we departed at 11pm… putting us in Columbus after 2am! It was awful. Had I known about the delay, I could have spent some time in the United Lounge… I was starving because I started my journey in Budapest… so I was exhausted and hungry. Plus I had to make new arrangements to be picked up at the airport in Columbus, instead of midnight it was 2:30 am after getting luggage and out of airport. Not feasible. I would have just stayed in Chicago for the night and gotten a morning flight.

It was great, I’m very grateful for the pilots and crew flight attendants for everything.

Evidently, my seat had the only broken TV. I couldn’t plug it in, get it to come on, or watch anything, and of course, no one could fix it while we were on the plane. The service was good and the boarding was quick

I was charged for my daughters bag when I am supposed to receive two free checked bags with my United Explorer card.

The schedule to Moline changed 5 times. The gate changed 6 times. That is a pathetic way to run an airline. No wonder that no one in our company flies on United Express to or from Moline. Changes happen most of the time. I learned my lesson on this trip…never again!

Flight was great. Efficient boarding. Short flight. Early arrival. Friendly flight crew. The entertainment system did not work well. Could not access it until the aircraft reached 10K feet or more. Lots of glitches.

A bit rush for transit. Food and entertainment are not available

Smooth boarding process. Early departure, smooth flight, early arrival. The entertainment package has very good recent movie options. The flight crew were friendly and professional.

My flight was scheduled for about 6:05 departure. There were 11 gate changes from 4-7pm and the flight was 3 hours delayed due to operational issues. The plane taxied around the airport for about half an hour before stopping to be de-iced. It would have been nice if we were alerted of the plan to de-ice prior to the 30 minute drive around the airport. The flight attendant was friendly, which was the only redeeming thing about this flight. As a former flight attendant for United, I was extremely disappointed.

Delays took 2hours and thirty minutes making me miss my connecting flight and make me sit in the Chicago airport for 9 hours

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

After a two hour delay, my flight was CANCELLED! No pilot available. Such BS.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

I wish American Airlines would change the airline industry by loading the plane back to front instead of front to back. Planes would board so much more smoothly and quickly.

I have long legs, my foot was out in the aisle and when a flight attendant came walking by and I didn't notice, instead of saying "excuse me" or anything like that, she kicked my foot. Extremely rude

Excellent! The gate agents were kind enough to rebook me on an earlier flight saving me from a 6 hour layover. Even my luggage made it despite the fact that the connection was technically too narrow. The flight itself was very comfortable, roomy, and clean. Plenty of space for my carryon items with plugs to charge my phone. After a long international flight of 14 hours, this was an excellent way to end my travels!

At least it was a short flight. Greyhound with wings.

Great experience. Flight boarded easily. Departed early. Smooth flight. Great arrival in DC--almost no taxing! Almost direct to gate from runway. Crew was terrific. Same cookies and beverages in main cabin. I did not use the entertainment system on this flight.

Most of the delay was due to weather which is not what was at issue here. One delay was due to a missing flashlight and in the end the flashlight was actually found on the plane. The entertainment system is very limited. Live TV options offer only a few channels that are not very appealing. Boarding and deplaning are always difficult. It just takes too much time to get on and off the plane. On the plus side, I missed my connecting flight, but was easily able to book a later flight from the app while enroute.

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

Everything you need to know for your flight from Chicago to Knoxville

Information on your arrival and departure airports

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