$542 Find Cheap Flights from Knoxville to Chile

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Chile departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Knoxville to Chile

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Santiago
Santiago3 stops$680
Santiago
Santiago3 stops$680

Book Cheap Knoxville to Chile Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Chile that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Chile

Thu, Aug 21 - Mon, Aug 25
 Logo
9:12 pm - 4:45 amTYS-SCL
31h 33m3 stops
 Logo
4:11 am - 11:12 pmSCL-TYS
19h 01m2 stops
Thu, Aug 21 - Mon, Aug 25
 Logo
7:30 am - 5:02 amTYS-SCL
21h 32m2 stops
 Logo
4:11 am - 11:12 pmSCL-TYS
19h 01m2 stops
Thu, Aug 21 - Mon, Aug 25
American Airlines Logo
7:00 am - 6:55 amTYS-SCL
23h 55m1 stop
American Airlines Logo
9:55 pm - 11:46 pmSCL-TYS
25h 51m1 stop
$732American Airlines
Find Deal
Thu, Aug 21 - Mon, Aug 25
American Airlines Logo
12:56 pm - 6:55 amTYS-SCL
17h 59m2 stops
American Airlines Logo
9:55 pm - 11:46 pmSCL-TYS
25h 51m1 stop
$737American Airlines
Find Deal
Thu, Aug 21 - Mon, Aug 25
 Logo
9:12 pm - 5:25 amTYS-SCL
32h 13m3 stops
 Logo
2:30 pm - 7:24 pmSCL-TYS
28h 54m3 stops
Mon, Aug 18 - Fri, Aug 22
LATAM Airlines Logo
7:16 pm - 12:20 pmTYS-SCL
17h 04m2 stops
LATAM Airlines Logo
5:35 am - 11:48 pmSCL-TYS
18h 13m2 stops
$914LATAM Airlines
Find Deal
Mon, Aug 18 - Fri, Aug 22
LATAM Airlines Logo
7:16 pm - 12:20 pmTYS-SCL
17h 04m2 stops
LATAM Airlines Logo
5:35 am - 11:48 pmSCL-TYS
18h 13m2 stops
$934LATAM Airlines
Find Deal
Thu, Aug 21 - Sun, Aug 24
Copa Airlines Logo
7:25 pm - 7:24 pmTYS-SCL
23h 59m2 stops
Copa Airlines Logo
2:26 am - 8:56 pmSCL-TYS
18h 30m2 stops
$1,179Copa Airlines
Find Deal
Mon, Aug 18 - Thu, Aug 21
Copa Airlines Logo
5:45 am - 10:44 pmTYS-SCL
16h 59m2 stops
Copa Airlines Logo
12:13 am - 8:56 pmSCL-TYS
20h 43m2 stops
$1,277Copa Airlines
Find Deal
Tue, Aug 26 - Tue, Sep 2
Delta Logo
4:19 pm - 2:00 pmTYS-SCL
21h 41m2 stops
Delta Logo
8:40 pm - 10:42 amSCL-TYS
14h 02m1 stop
$3,034Delta
Find Deal
Booking Insights

KAYAK's insights & trends for Knoxville to Chile flights

Get data-powered insights and trends into flights from Knoxville to Chile to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Chile?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Chile were found on American Airlines ($732) and LATAM Airlines ($914).


Good to know

Cheapest flight$542
Flight from Knoxville to Santiago

FAQs - booking Chile flights

  • How does KAYAK find such low prices on flights from Knoxville to Chile?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Chile.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Chile?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to Chile is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Chile?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to Chile with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Chile?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to Chile up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Chile?

    The cheapest time of day to fly to Chile is generally in the evening, when round-trip flights cost $970 on average. On average, there is no price difference when choosing to fly in the morning or the evening on this flight route. The most expensive time of day to fly to Chile is generally at night, which is peak travel time and where the average cost of a ticket is $1,327.

Reviews of the top airline flying from Knoxville to Chile

 
Need help choosing which airline to fly with from Knoxville to Chile? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
6.9Entertainment
8.0Crew
6.5Food
7.5Boarding
7.2Comfort
Airline reviews

We had to turn around and head back to Manchester. Problem with a plane engine.

2.0 MediocreAnonymous, Jul 2025MHT - CLT
Read more American Airlines reviews

We had to turn around and head back to Manchester. Problem with a plane engine.

Flight was delayed. Staff at the gate effectively and proactively communicated about the delay.

Very poor delay in dfw was really bad n long

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

Everything you need to know for your flight from Knoxville to Chile

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