TYS - SCL

$878 Find Cheap Flights from Knoxville to Santiago

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Santiago departing on 7/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Santiago, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Knoxville to Santiago (TYS-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Santiago

dom., jul. 20 - sáb., jul. 26
Copa Airlines Logo
6:58 pm - 7:24 pmTYS-SCL
24h 26m2 stops
Copa Airlines Logo
11:27 am - 10:27 amSCL-TYS
23h 00m2 stops
$878Copa Airlines
Find Deal
mar., ago. 5 - lun., ago. 18
American Airlines Logo
12:14 pm - 7:05 amTYS-SCL
18h 51m2 stops
American Airlines Logo
9:55 pm - 4:48 pmSCL-TYS
18h 53m2 stops
$903American Airlines
Find Deal
mar., ago. 5 - lun., ago. 18
American Airlines Logo
6:00 pm - 7:05 amTYS-SCL
13h 05m2 stops
American Airlines Logo
9:55 pm - 11:41 pmSCL-TYS
25h 46m1 stop
$913American Airlines
Find Deal
mar., ago. 5 - lun., ago. 18
Delta Logo
5:57 pm - 7:00 amTYS-SCL
13h 03m1 stop
Delta Logo
8:40 pm - 3:08 pmSCL-TYS
18h 28m1 stop
$944Delta
Find Deal
dom., jun. 29 - dom., jul. 6
 Logo
9:08 pm - 1:45 pmTYS-SCL
40h 37m3 stops
 Logo
6:10 am - 4:47 pmSCL-TYS
34h 37m2 stops
dom., jun. 29 - dom., jul. 6
 Logo
9:08 pm - 1:45 pmTYS-SCL
40h 37m3 stops
 Logo
8:40 pm - 11:59 pmSCL-TYS
27h 19m3 stops
$1,219
Find Deal
dom., jun. 29 - sáb., jul. 5
LATAM Airlines Logo
5:57 pm - 7:00 amTYS-SCL
13h 03m1 stop
LATAM Airlines Logo
12:37 am - 10:11 pmSCL-TYS
21h 34m2 stops
$1,689LATAM Airlines
Find Deal
sáb., jun. 7 - dom., jun. 15
LATAM Airlines Logo
4:20 pm - 12:35 pmTYS-SCL
20h 15m3 stops
LATAM Airlines Logo
11:25 pm - 6:59 pmSCL-TYS
19h 34m2 stops
$1,818LATAM Airlines
Find Deal
mié., ago. 6 - dom., ago. 17
Delta Logo
2:33 pm - 7:00 amTYS-SCL
16h 27m1 stop
Delta Logo
12:40 am - 9:45 pmSCL-TYS
21h 05m2 stops
$2,219Delta
Find Deal
mar., ago. 26 - mar., sep. 2
Avianca Logo
7:00 am - 4:15 amTYS-SCL
21h 15m2 stops
Avianca Logo
11:55 pm - 10:35 pmSCL-TYS
22h 40m2 stops
$2,780Avianca
Find Deal
Useful Info

KAYAK's insights & trends for Knoxville to Santiago flights

Get data-powered insights and trends into flights from Knoxville to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Santiago?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Santiago were found on Copa Airlines ($878) and American Airlines ($903).

Good to know

Cheapest flight$878
Flight from Knoxville to Santiago

When to book flights from Knoxville to Santiago

Are your dates flexible? Find out the best times to travel from Knoxville to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Santiago

  • What is the cheapest flight from Knoxville to Santiago?

    In the last 3 days, the lowest price for a flight from Knoxville to Santiago was $878 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Knoxville and on arrival in Santiago.

  • Which aircraft models fly most regularly from Knoxville to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Santiago?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Knoxville and Santiago, with Star Alliance being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Knoxville to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top airline flying from Knoxville to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
6.9Entertainment
7.2Comfort
7.5Boarding
6.5Food
8.0Crew
Airline reviews

Waited on the runway for takeoff for 2.5 hours. Air traffic rerouted us. The plane didn't have enough fuel, so had to go back to the gate. Had to wait for a new pilot. Should have landed at 5:22. Didn't land until 9:10. Trash flight.

2.0 MediocreAnonymous, May 2025LGA - MCO
Read more American Airlines reviews

Waited on the runway for takeoff for 2.5 hours. Air traffic rerouted us. The plane didn't have enough fuel, so had to go back to the gate. Had to wait for a new pilot. Should have landed at 5:22. Didn't land until 9:10. Trash flight.

DFW-LHR Toilets not kept clean Too cramped. Aisles so narrow crew were constantly banging into people on the aisle seats. Even then, the carts used are reduced width. Other than that it was a decent flight on both legs

Eventless. It was a good flight and good crew. Can’t complaint.

At the beginning of the flight there was some turbulence and the announcement was made that there would be no beverage service. The turbulence only last about 5 minutes then it was smooth sailing. I noticed that first class got their service, but the rest of us did not.

Update departure times in a more timely manner. We are not boarding on time if the plane isn’t arriving until after our scheduled departure time.

Update.us on flight information in a more timely manner. Don’t say we are boarding on time ten minutes before the boarding time when the aircraft isn’t arriving for another forty minutes.

The boarding was pretty easy. However, the first class seats are not lay flat as other airlines (like JetBlue) has and therefore sleeping was a challenge.

It was nobody’s fault - but the plane came 4-hrs late and we were updated randomly in 20-30 mins increments which left us hostage to sit and wait expectantly. It was very long and got very late. Our plane didn’t land until nearly 1 am! Also the toilet wasn’t working. The hosts were nice enough but were clearly “about to pass out” as one told me. Lastly, there was no snack or even time for it. Just a bad experience overall.

Was a normal flight but it was delayed, and there wasn't an explanation.

In flight connectivity (via T-Mobile) was often not working.

Everything you need to know for your flight from Knoxville to Santiago

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