$106 Find Cheap Flights from Knoxville to Florida Keys

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Florida Keys departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Florida Keys

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Florida Keys, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Florida Keys, as well as popular online travel agencies
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Cheap Flights from Knoxville to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miaminonstop$159
Key West
Key West1 stop$238
Miami
Miaminonstop$159
Key West
Key West1 stop$238

Book Cheap Knoxville to Florida Keys Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Florida Keys

Sat, Sep 13 - Sat, Sep 20
American Airlines Logo
6:10 am - 8:18 amTYS-MIA
2h 08mnonstop
American Airlines Logo
9:35 pm - 11:50 pmMIA-TYS
2h 15mnonstop
$159American Airlines
Find Deal
Wed, Aug 27 - Wed, Sep 3
American Airlines Logo
7:00 am - 9:08 amTYS-MIA
2h 08mnonstop
American Airlines Logo
9:35 pm - 11:50 pmMIA-TYS
2h 15mnonstop
$174American Airlines
Find Deal
Sun, Aug 31 - Sat, Sep 6
Delta Logo
6:14 pm - 12:24 amTYS-MIA
6h 10m1 stop
Delta Logo
7:30 am - 1:12 pmMIA-TYS
5h 42m1 stop
$193Delta
Find Deal
Wed, Aug 27 - Wed, Sep 3
Delta Logo
5:45 am - 10:52 amTYS-MIA
5h 07m1 stop
Delta Logo
2:45 pm - 7:03 pmMIA-TYS
4h 18m1 stop
$194Delta
Find Deal
Fri, Sep 19 - Mon, Sep 22
Allegiant Air Logo
7:34 pm - 9:02 amTYS-EYW
13h 28m1 stop
Allegiant Air Logo
3:44 pm - 8:59 pmEYW-TYS
5h 15m1 stop
$238Allegiant Air
Find Deal
Thu, Aug 28 - Mon, Sep 1
Frontier Logo
8:36 pm - 6:30 amTYS-MIA
9h 54m1 stop
Frontier Logo
6:00 am - 6:25 pmMIA-TYS
12h 25m1 stop
$258Frontier
Find Deal
Fri, Sep 19 - Sun, Sep 21
 Logo
1:22 pm - 12:21 pmTYS-MIA
22h 59m2 stops
 Logo
8:04 pm - 11:55 amMIA-TYS
15h 51m1 stop
Fri, Sep 19 - Sun, Sep 21
 Logo
7:15 am - 5:02 pmTYS-MIA
9h 47m1 stop
 Logo
8:04 pm - 11:55 amMIA-TYS
15h 51m1 stop
Thu, Sep 18 - Mon, Sep 22
Frontier Logo
8:40 pm - 12:44 amTYS-MIA
28h 04m1 stop
Frontier Logo
6:00 am - 7:45 pmMIA-TYS
13h 45m1 stop
$265Frontier
Find Deal
Fri, Oct 3 - Fri, Oct 10
Allegiant Air Logo
9:54 pm - 9:02 amTYS-EYW
11h 08m1 stop
Allegiant Air Logo
3:08 pm - 9:04 pmEYW-TYS
5h 56m1 stop
$273Allegiant Air
Find Deal
Booking Insights

KAYAK's insights & trends for Knoxville to Florida Keys flights

Get data-powered insights and trends into flights from Knoxville to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Knoxville to Florida Keys flight route?

The cheapest price for flight routes found by users searching on KAYAK in the last 2 weeks for round-trip flights from Knoxville to Florida Keys.

The cheapest ticket to Florida Keys from Knoxville found in the last 72 hours was to Key West, at $100 round-trip. The most popular route is from Knoxville (TYS) to Key West (EYW), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $100.

Can I save money by flying with a layover from Knoxville to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $434, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Knoxville to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Florida Keys is August, when tickets cost $313 (return) on average. On the other hand, the most expensive months are May and March, when the average cost of round-trip tickets is $467 and $435 respectively.

What’s the cheapest day of the week to fly from Knoxville to Florida Keys?

The average price of all round-trip flights from Knoxville to Florida Keys clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Florida Keys on a Monday and more expensive on a Wednesday. On your return trip to Knoxville, you should consider flying back on a Tuesday, and avoid Mondays for better deals.

How far in advance should I book a flight from Knoxville to Florida Keys?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Knoxville to Florida Keys, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Knoxville to Florida Keys, you should book around 2 weeks before departure, which saves you about 23% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 8 weeks before departure.


Good to know

Low seasonMay
Cheapest flight$106
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Knoxville to Key West

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Knoxville to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Florida Keys?

    The cheapest time of day to fly to Florida Keys is generally in the evening, when round-trip flights cost $366 on average. Morning departures are around 57% more expensive than evening flights, on average. The most expensive time of day to fly to Florida Keys is generally at night, which is peak travel time and where the average cost of a ticket is $735.

Top tips for finding cheap flights to Florida Keys

  • Looking for a cheap flight? 25% of our users found tickets from Knoxville to the following destinations at these prices or less: Miami $274 one-way - $383 round-trip

Reviews of the top 3 airlines serving from Knoxville to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7980 reviews
7.9Comfort
8.5Crew
8.2Boarding
7.3Food
7.9Entertainment
Airline reviews

Delayed and took off even later than the scheduled delay time

8.0 ExcellentAnonymous, Jul 2025DTW - SEA
Read more Delta reviews

Delayed and took off even later than the scheduled delay time

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Great experience on Delta. Staff from baggage check to flight attendants were very courteous and professional. My only issue was a personal preference for pretzels instead of the chips and cookies that were offered.

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

this crew didn't care much. bumping carts into seats more times than i care to remember

Everything was fine except the entertainment was not working for half of the flight.

Easy boarding with an extremely kind attendant. Seats were spacious and we had 3 seats for 2 people so we could stretch out. Comfortable air flow and very attentive and hospital attendants. Bathrooms and food were the only negative. Bathrooms were so small you could hardly get in and close the door. I don’t think an obese person would fit or a person with a movement disability. Food was the trending food for flights, nonexistent. We spent $40 getting sandwich and snack at airport for our 6 hour flught.

I am very bothered by the events today. I can't believe the flight attendants allowed someone to take my seat and made me move. It was embarrassing. I was in the right. The lady just didn't want move. I can't believe delta would allow this to stand and disrespect my rights as a passenger. The lady complained about her leg and that she couldn't move. Firstly somehow she was able to make it to row 24. Not sure how much her leg could have hurt. Secondly, I'm in plenty of pain myself. I just finished chemotherapy a several weeks ago. My body is constantly sore. Yet deltas flight attendants didn't appropriately protect my rights. In the end they found me a seat on the plane but I want to understand how delta can operate this way. They in essence allowed a bully to get their way.

Good flights. On time. They had a gluten free snack option which was nice

Crew was friendly Love the entertainment in the seat head rest.

Flight delays numerous times. Everytime we would get close to boarding it would be delayed again. Strung along the entire time.

This flight never occurred because AA couldn’t get their act together.

During service there was a garbage/beverage spill near our seats that never was cleaned up. On a relatively short flight when we’re fortunate enough to actually have in flight movies available, the flight attendants pitching the AADVANTAGE credit card shouldn’t talk for the last 10 minutes of the flight so that we miss the end of the movie.

Waited on the runway for takeoff for 2.5 hours. Air traffic rerouted us. The plane didn't have enough fuel, so had to go back to the gate. Had to wait for a new pilot. Should have landed at 5:22. Didn't land until 9:10. Trash flight.

The boarding was pretty easy. However, the first class seats are not lay flat as other airlines (like JetBlue) has and therefore sleeping was a challenge.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

Would have thought that they would gas up plane before everyone got on board

Fine. On time, cabin service was fine, bag arrived. All good. Flying into DCA so did not collide with any helicopters, which is also good. Horrid incident that could have and should have been prevented.

I didn’t like anything, being platinum pro get you absolutely nowhere and does not increase the customer service treatment whatsoever anymore. My flight was canceled and they put me on a flight eight hours later that would’ve got me back in the middle of the night. They could’ve easily move me up to an hour Prior on an earlier flight. My second flight was unreasonable to take, the third flight was also canceled due to mechanical issues like the first flight. I don’t know what’s going on with American, but they are falling apart, after seven flight changes I finally got home, Unreasonable.

Standard. No different than a discount carrier on a short trip.

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

Everything you need to know for your flight to Florida Keys

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