$78 Find Cheap Flights from Knoxville to Florida Keys

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Florida Keys departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Florida Keys

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Florida Keys, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Florida Keys, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Knoxville to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miaminonstop$163
Key West
Key Westnonstop$95
Miami
Miaminonstop$163
Key West
Key Westnonstop$95

Book Cheap Knoxville to Florida Keys Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Florida Keys

Mon, Oct 20 - Fri, Oct 24
Allegiant Air Logo
12:55 pm - 3:06 pmTYS-EYW
2h 11mnonstop
Allegiant Air Logo
3:39 pm - 5:54 pmEYW-TYS
2h 15mnonstop
$95Allegiant Air
Find Deal
Mon, Dec 8 - Fri, Dec 12
Allegiant Air Logo
11:28 am - 1:39 pmTYS-EYW
2h 11mnonstop
Allegiant Air Logo
2:29 pm - 4:44 pmEYW-TYS
2h 15mnonstop
$155Allegiant Air
Find Deal
Sat, Dec 6 - Sat, Dec 13
American Airlines Logo
5:03 pm - 7:20 pmTYS-MIA
2h 17mnonstop
American Airlines Logo
9:34 pm - 11:57 pmMIA-TYS
2h 23mnonstop
$163American Airlines
Find Deal
Wed, Oct 29 - Wed, Nov 5
American Airlines Logo
6:15 am - 8:22 amTYS-MIA
2h 07mnonstop
American Airlines Logo
2:21 pm - 4:37 pmMIA-TYS
2h 16mnonstop
$164American Airlines
Find Deal
Sun, Sep 28 - Thu, Oct 2
Frontier Logo
5:08 pm - 12:44 amTYS-MIA
7h 36m1 stop
Frontier Logo
6:00 am - 7:50 pmMIA-TYS
13h 50m1 stop
$182Frontier
Find Deal
Tue, Oct 28 - Thu, Nov 6
Delta Logo
5:44 am - 9:35 amTYS-MIA
3h 51m1 stop
Delta Logo
8:11 am - 2:51 pmMIA-TYS
6h 40m1 stop
$183Delta
Find Deal
Fri, Oct 24 - Mon, Oct 27
Frontier Logo
8:17 pm - 6:19 amTYS-MIA
10h 02m1 stop
Frontier Logo
6:00 am - 7:32 pmMIA-TYS
13h 32m1 stop
$225Frontier
Find Deal
Fri, Nov 7 - Thu, Nov 13
 Logo
6:12 pm - 4:51 pmTYS-MIA
22h 39m2 stops
 Logo
6:00 am - 6:22 pmMIA-TYS
12h 22m1 stop
Mon, Sep 29 - Sat, Oct 4
 Logo
12:45 pm - 11:00 pmTYS-MIA
10h 15m1 stop
 Logo
5:35 pm - 4:44 pmMIA-TYS
23h 09m2 stops
Fri, Sep 26 - Tue, Sep 30
Delta Logo
12:01 pm - 5:15 pmTYS-EYW
5h 14m1 stop
Delta Logo
6:10 pm - 11:44 pmEYW-TYS
5h 34m1 stop
$284Delta
Find Deal
Booking Insights

KAYAK's insights & trends for Knoxville to Florida Keys flights

Get data-powered insights and trends into flights from Knoxville to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Knoxville to Florida Keys flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Florida Keys from Knoxville found in the last 72 hours was to Key West, at $94 round-trip. The most popular route is from Knoxville (TYS) to Key West (EYW), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $94.

Can I save money by flying with a layover from Knoxville to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $264, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Knoxville to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Florida Keys is July, when tickets cost $365 (return) on average. On the other hand, the most expensive months are May and March, when the average cost of round-trip tickets is $471 and $435 respectively.

What’s the cheapest day of the week to fly from Knoxville to Florida Keys?

The average price of all round-trip flights from Knoxville to Florida Keys clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Florida Keys on a Saturday and more expensive on a Wednesday. On your return trip to Knoxville, you should consider flying back on a Tuesday, and avoid Mondays for better deals.

How far in advance should I book a flight from Knoxville to Florida Keys?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Knoxville to Florida Keys, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Knoxville to Florida Keys, you should book around 3 weeks before departure, which saves you about 19% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 8 weeks before departure.

Good to know

Low seasonJuly
Cheapest flight$78
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 17% lower on average.
Flight from Knoxville to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Knoxville to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Florida Keys?

    The cheapest time of day to fly to Florida Keys is generally in the afternoon, when round-trip flights cost $399 on average. Morning departures are around 37% more expensive than evening flights, on average. The most expensive time of day to fly to Florida Keys is generally at night, which is peak travel time and where the average cost of a ticket is $735.

  • How many flights are there between Knoxville and Florida Keys per day?

    There is a maximum of 1 nonstop flight a day that takes off from Knoxville and lands in Florida Keys, with an average flight time of 2h 11m. The most common departure time is 11:00 am and most flights take off in the morning. Each week, there are 2 flights.

Top tips for finding cheap flights to Florida Keys

  • Looking for a cheap flight? 25% of our users found tickets from Knoxville to the following destinations at these prices or less: Miami $286 one-way - $434 round-trip

Reviews of the top 3 airlines serving from Knoxville to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7954 reviews
7.9Entertainment
8.2Boarding
8.5Crew
7.3Food
7.9Comfort
Airline reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

10.0 ExcellentAnonymous, Sep 2025CLT - BOS
Read more Delta reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

this crew didn't care much. bumping carts into seats more times than i care to remember

Everything was fine except the entertainment was not working for half of the flight.

Easy boarding with an extremely kind attendant. Seats were spacious and we had 3 seats for 2 people so we could stretch out. Comfortable air flow and very attentive and hospital attendants. Bathrooms and food were the only negative. Bathrooms were so small you could hardly get in and close the door. I don’t think an obese person would fit or a person with a movement disability. Food was the trending food for flights, nonexistent. We spent $40 getting sandwich and snack at airport for our 6 hour flught.

I am very bothered by the events today. I can't believe the flight attendants allowed someone to take my seat and made me move. It was embarrassing. I was in the right. The lady just didn't want move. I can't believe delta would allow this to stand and disrespect my rights as a passenger. The lady complained about her leg and that she couldn't move. Firstly somehow she was able to make it to row 24. Not sure how much her leg could have hurt. Secondly, I'm in plenty of pain myself. I just finished chemotherapy a several weeks ago. My body is constantly sore. Yet deltas flight attendants didn't appropriately protect my rights. In the end they found me a seat on the plane but I want to understand how delta can operate this way. They in essence allowed a bully to get their way.

Good flights. On time. They had a gluten free snack option which was nice

Crew was friendly Love the entertainment in the seat head rest.

Lower number on this flight so spaced out passengers. Able to enjoy more room to relax during flight. It was lovely.

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Flight delays numerous times. Everytime we would get close to boarding it would be delayed again. Strung along the entire time.

This flight never occurred because AA couldn’t get their act together.

During service there was a garbage/beverage spill near our seats that never was cleaned up. On a relatively short flight when we’re fortunate enough to actually have in flight movies available, the flight attendants pitching the AADVANTAGE credit card shouldn’t talk for the last 10 minutes of the flight so that we miss the end of the movie.

Waited on the runway for takeoff for 2.5 hours. Air traffic rerouted us. The plane didn't have enough fuel, so had to go back to the gate. Had to wait for a new pilot. Should have landed at 5:22. Didn't land until 9:10. Trash flight.

The boarding was pretty easy. However, the first class seats are not lay flat as other airlines (like JetBlue) has and therefore sleeping was a challenge.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

Would have thought that they would gas up plane before everyone got on board

Fine. On time, cabin service was fine, bag arrived. All good. Flying into DCA so did not collide with any helicopters, which is also good. Horrid incident that could have and should have been prevented.

Crew was great. No entertainment and food and beverage was for purchase only, even water

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

Everything you need to know for your flight to Florida Keys

Information on your arrival and departure airports

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