TYS - EYW

$47 Find Cheap Flights from Knoxville to Key West - Compare and Save

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Everything you should know

Cheapest round-trip
$74
Typical prices: $109-$269
Allegiant Air
Fri 10/19Tue 10/23
TYS - EYW • Non-stop
Cheapest one-way
$47
Typical prices: $67-$131
Allegiant Air
Fri 12/14
TYS - EYW • Non-stop
Nonstop flights
2 days a week
You can fly direct with Allegiant Air. Average duration is 2h 06m
Direct flights
+1
Direct flights
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 61% compared to booking last minute.
Insights
Insights
When to travel
August
Cheapest • 39% price drop
January
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Tampa St. Petersburg (PIE)
Cheapest • Avg $295 (round-trip)
Miami (MIA)
Shortest trip • 4h 38m (one-way)
Insights
Insights
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We hope you love your trip to Key West!
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Flight Deals

Cheap Flights from Knoxville to Key West (TYS-EYW)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Key West

Mon, Oct 19 - Fri, Oct 23
Allegiant Air Logo
9:00 am - 11:04 amTYS  Knoxville McGhee Tyson-EYW Key West
2h 04mnonstop
Allegiant Air Logo
9:54 am - 12:07 pmEYW  Key West-TYS Knoxville McGhee Tyson
2h 13mnonstop
$74Allegiant Air
Mon, Oct 19 - Fri, Oct 23
Allegiant Air Logo
9:00 am - 11:04 amTYS  Knoxville McGhee Tyson-EYW Key West
2h 04mnonstop
Allegiant Air Logo
9:54 am - 12:07 pmEYW  Key West-TYS Knoxville McGhee Tyson
2h 13mnonstop
$78Allegiant Air
Mon, Oct 19 - Fri, Oct 23
Allegiant Air Logo
9:00 am - 11:04 amTYS  Knoxville McGhee Tyson-EYW Key West
2h 04mnonstop
Allegiant Air Logo
9:54 am - 12:07 pmEYW  Key West-TYS Knoxville McGhee Tyson
2h 13mnonstop
$82Allegiant Air
Mon, Oct 19 - Fri, Oct 23
Allegiant Air Logo
9:00 am - 11:04 amTYS  Knoxville McGhee Tyson-EYW Key West
2h 04mnonstop
Allegiant Air Logo
9:54 am - 12:07 pmEYW  Key West-TYS Knoxville McGhee Tyson
2h 13mnonstop
$83Allegiant Air
Mon, Oct 19 - Fri, Oct 23
Multiple Airlines Logo
9:00 am - 11:04 amTYS  Knoxville McGhee Tyson-EYW Key West
2h 04mnonstop
Multiple Airlines Logo
10:59 am - 9:44 amEYW  Key West-TYS Knoxville McGhee Tyson
46h 45m2 stops Orlando Washington, D.C. Dulles Intl
$176Multiple Airlines
Mon, Oct 19 - Fri, Oct 23
Multiple Airlines Logo
9:00 am - 11:04 amTYS  Knoxville McGhee Tyson-EYW Key West
2h 04mnonstop
Multiple Airlines Logo
10:59 am - 9:44 amEYW  Key West-TYS Knoxville McGhee Tyson
46h 45m2 stops Orlando Washington, D.C. Dulles Intl
$183Multiple Airlines
Mon, Oct 19 - Fri, Oct 23
Multiple Airlines Logo
9:00 am - 11:04 amTYS  Knoxville McGhee Tyson-EYW Key West
2h 04mnonstop
Multiple Airlines Logo
10:59 am - 9:44 amEYW  Key West-TYS Knoxville McGhee Tyson
46h 45m2 stops Orlando Washington, D.C. Dulles Intl
$184Multiple Airlines
Fri, Feb 26 - Tue, Mar 2
American Airlines Logo
4:15 pm - 10:43 pmTYS  Knoxville McGhee Tyson-EYW Key West
6h 28m1 stop Charlotte Douglas
American Airlines Logo
4:40 pm - 11:52 pmEYW  Key West-TYS Knoxville McGhee Tyson
7h 12m1 stop Charlotte Douglas
$339American Airlines
Sat, Oct 17 - Tue, Oct 20
American Airlines Logo
1:39 pm - 7:33 pmTYS  Knoxville McGhee Tyson-EYW Key West
5h 54m1 stop Miami
American Airlines Logo
5:28 pm - 10:59 pmEYW  Key West-TYS Knoxville McGhee Tyson
5h 31m1 stop Miami
$339American Airlines
Sat, Oct 17 - Tue, Oct 20
American Airlines Logo
1:39 pm - 7:33 pmTYS  Knoxville McGhee Tyson-EYW Key West
5h 54m1 stop Miami
American Airlines Logo
5:28 pm - 10:59 pmEYW  Key West-TYS Knoxville McGhee Tyson
5h 31m1 stop Miami
$339American Airlines
Booking Insights

Price, demand and travel trends for Knoxville to Key West flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Knoxville to Key West?

Round-trip flights from Knoxville to Key West typically range from $109 to $269. The lowest price found in the past 5 days was $74, on Allegiant Air.

What's the cheapest day of the week to fly from Knoxville to Key West?

Based on deals KAYAK users found in the last 12 months, Monday is the cheapest day of the week to fly from Knoxville to Key West. It’s 33% cheaper than the average day, while Tuesday is the most expensive, with prices 301% higher.

What’s the cheapest month to fly from Knoxville to Key West?

•August is the cheapest month to fly from Knoxville to Key West at $96 round-trip.
•September ($308) and January ($268) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 220% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Knoxville to Key West the cheapest?

Flights from Knoxville to Key West are cheapest 3 weeks before departure. Booking in this window typically costs about 61% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Knoxville to Key West flights

Low season

October

Cheapest flight

$47
One-way flight from Knoxville to Key West

When to book flights from Knoxville to Key West

Are your dates flexible? Find out the best times to travel from Knoxville to Key West based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Key West flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What are the earliest and latest flights from Knoxville to Key West?

    These are the earliest and latest flight times available from Knoxville to Key West:

    • Earliest: departs at 6:20 am and lands at 8:26 am
    • Latest: departs at 2:48 pm and lands at 4:54 pm.

    The flight takes about 2h 06m.

  • What cabin classes can I book on flights from Knoxville to Key West?

    Only Economy Class is available on flights from Knoxville to Key West.

  • How long is a flight from Knoxville to Key West?

    A nonstop flight from Knoxville to Key West takes 2h 06m, covering 788 miles.

  • Do I need a passport to fly from Knoxville to Key West?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Knoxville to Key West flight?

    Round-trip flights from Knoxville to Key West range from $109 to $269, with an average of $158 over the past 12 months. Anything below $109 counts as a good deal.

  • How expensive are last-minute Knoxville to Key West flights?

    Last-minute fares on this route (booked within two weeks of departure) run 63% above the $158 route average. Book 3 weeks before departure for the lowest fares.

  • How much can I save by taking a layover when flying from Knoxville to Key West?

    On this route, nonstop flights are cheaper than layover options on average. Nonstop fares average $128 round-trip, compared to $295 via a layover through Tampa St. Petersburg (PIE).

  • What is the standard checked-bag allowance on flights from Knoxville to Key West?

    There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $45–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from Knoxville to Key West?

    The Airbus A320-100/200 family is used most often on this route, operated mainly by Allegiant Air. Other aircraft seen on the route include Airbus A319 variants.

  • How are flight prices from Knoxville to Key West looking right now?

    One-way fares from Knoxville to Key West are currently higher than usual. Average one-way flight prices are about $170, which is 75% above the typical average for this route.

  • What car rental options are available at Key West Airport (EYW)?

    Key West Airport (EYW) hosts 5 major car rental companies, with daily rates starting from around $29 for economy cars. Top options include:

    • Dollar
    • Hertz
    • Budget
    • Enterprise Rent-A-Car
    • Alamo

  • Which airports can I use when flying from Knoxville to Key West?

    Flights from Knoxville to Key West usually depart from Knoxville McGhee Tyson (TYS) and arrive at Key West (EYW).

  • Which airports do connecting flights from Knoxville to Key West pass through?

    One-stop flights from Knoxville to Key West most commonly connect through:

    • Miami (MIA) - 34% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 28% of one-stop connections
    • Charlotte Douglas (CLT) - 16% of one-stop connections
    • Tampa St. Petersburg (PIE) - 16% of one-stop connections

  • Can I save money by using flexible dates for flights from Knoxville to Key West?

    Yes. Flexible dates can save you up to 84% on flights from Knoxville to Key West. Monday is the cheapest departure day at $106 round-trip on average, while Tuesday is the most expensive at $634, a difference of $528.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What airlines fly from Knoxville to Key West?

    Only Allegiant Air operates flights between Knoxville and Key West.

  • How much time can I save by choosing a different layover airport from Knoxville to Key West?

    Flying via Miami (MIA) gives the shortest average 1-stop total travel time at 4h 38m, compared with 4h 40m via Charlotte Douglas (CLT) and 4h 48m via Atlanta Hartsfield-Jackson (ATL).

  • What popular places can I visit in Key West?

    Some of the most popular sights in Key West are Duval Street, Key West Historic District and Mallory Square. These are among the most viewed places in Key West on KAYAK.

Your guide to booking Knoxville to Key West flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Monday departure and avoid flying on Tuesday. On this route, Monday flights average $106, about $528 less than Tuesday fares (83% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 3 weeks before you fly. On this route, that window historically saves about 61% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Knoxville to Key West trip for August. Fares historically average $96 round-trip in that month - typically $212 less than the most expensive month, which is September (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Key West Airport.

    • Havana Cabana at Key West
    • Parrot Key Hotel & Villas
    • DoubleTree by Hilton Hotel Grand Key - Key West

Prefer to fly direct from Knoxville to Key West?

 
Find which airlines fly direct from Knoxville McGhee Tyson Airport to Key West Airport, which days they fly and book direct flights.

Direct departures

Knoxville McGhee Tyson to Key West

Monday

Allegiant Air

Allegiant Air

Wednesday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Key West to Knoxville McGhee Tyson

Monday

Allegiant Air

Allegiant Air

Wednesday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

More options for your flight from Knoxville to Key West

Complete your trip to Key West with a hotel stay or car rental

Car rentals in Key West
Hotels in Key West
Vacations in Key West