TYS

$88 Find Cheap Flights from Florida Keys to Knoxville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight to Knoxville departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Florida Keys to Knoxville

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Florida Keys to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Florida Keys to Knoxville

Fri, Oct 24 - Mon, Oct 27
Allegiant Air Logo
3:39 pm - 5:54 pmEYW-TYS
2h 15mnonstop
Allegiant Air Logo
6:02 pm - 8:13 pmTYS-EYW
2h 11mnonstop
$88Allegiant Air
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Thu, Nov 13 - Mon, Nov 17
American Airlines Logo
2:21 pm - 4:37 pmMIA-TYS
2h 16mnonstop
American Airlines Logo
6:00 am - 8:07 amTYS-MIA
2h 07mnonstop
$159American Airlines
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Thu, Nov 13 - Mon, Nov 17
American Airlines Logo
2:21 pm - 4:37 pmMIA-TYS
2h 16mnonstop
American Airlines Logo
6:00 am - 8:07 amTYS-MIA
2h 07mnonstop
$163American Airlines
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Tue, Sep 23 - Tue, Sep 30
American Airlines Logo
9:35 pm - 11:50 pmMIA-TYS
2h 15mnonstop
American Airlines Logo
6:10 am - 8:18 amTYS-MIA
2h 08mnonstop
$169American Airlines
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Tue, Sep 23 - Tue, Sep 30
Delta Logo
7:38 pm - 11:44 pmMIA-TYS
4h 06m1 stop
Delta Logo
5:45 am - 9:20 amTYS-MIA
3h 35m1 stop
$189Delta
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Fri, Oct 24 - Mon, Oct 27
Allegiant Air Logo
9:45 pm - 2:42 pmEYW-TYS
16h 57m1 stop
Allegiant Air Logo
6:02 pm - 8:13 pmTYS-EYW
2h 11mnonstop
$190Allegiant Air
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Sun, Nov 9 - Thu, Nov 13
Frontier Logo
6:00 am - 6:22 pmMIA-TYS
12h 22m1 stop
Frontier Logo
7:17 pm - 6:19 amTYS-MIA
11h 02m1 stop
$223Frontier
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Wed, Oct 15 - Sun, Oct 19
Delta Logo
6:15 pm - 11:07 pmMIA-TYS
4h 52m1 stop
Delta Logo
8:35 pm - 12:29 amTYS-MIA
3h 54m1 stop
$229Delta
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Mon, Oct 20 - Sun, Oct 26
United Airlines Logo
3:12 pm - 9:11 pmEYW-TYS
29h 59m2 stops
United Airlines Logo
6:45 am - 3:19 pmTYS-EYW
8h 34m1 stop
$438United Airlines
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Mon, Oct 20 - Sun, Oct 26
United Airlines Logo
3:12 pm - 10:29 amEYW-TYS
19h 17m2 stops
United Airlines Logo
9:50 am - 1:52 pmTYS-EYW
28h 02m2 stops
$558United Airlines
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Good to know

Low seasonJanuary
Cheapest flight$88
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Key West to Knoxville

FAQs for booking flights from Florida Keys to Knoxville

  • How does KAYAK find such low prices on flights from Florida Keys to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Florida Keys to Knoxville

 
Need help choosing which airline to fly with from Florida Keys to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7977 reviews
8.2Boarding
7.9Comfort
8.5Crew
7.3Food
7.9Entertainment
Airline reviews

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

2.0 MediocreRosa, Jul 2025TPA - JFK
Read more Delta reviews

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

Kind staff. Snacks are small but that’s the new normal.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Flight left early and arrived early. the whole trip was excellent.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Food was ok, but not as good as I have had before on AA.

Pretty good. The food was just mediocre, the boarding and crew were good.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

I was late from Jacksonville, FL but the limited interaction I had with the Philly crew was great.

The delays and cancellations kept me stuck in Miami for an additional 24 hours, and the whole thing seemed extremely disorganized

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

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