TYS

$65 Find Cheap Flights from Florida Keys to Knoxville - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Knoxville departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Florida Keys to Knoxville

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Florida Keys to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Florida Keys to Knoxville

Fri, Oct 30 - Mon, Nov 2
Multiple Airlines Logo
8:00 am - 8:05 pm
MIA
-
TYS
12h 05m
1 stop
Multiple Airlines Logo
2:12 pm - 6:12 pm
TYS
-
MIA
28h 00m
2 stops
$222Multiple Airlines
Mon, Oct 26 - Sat, Oct 31
Multiple Airlines Logo
6:45 am - 6:55 pm
MIA
-
TYS
12h 10m
1 stop
Multiple Airlines Logo
6:18 pm - 1:05 pm
TYS
-
MIA
18h 47m
2 stops
$229Multiple Airlines
Thu, Sep 10 - Thu, Sep 17
Multiple Airlines Logo
8:50 pm - 6:34 pm
MIA
-
TYS
21h 44m
1 stop
Multiple Airlines Logo
1:19 pm - 8:33 pm
TYS
-
MIA
31h 14m
2 stops
$233Multiple Airlines
Sun, Aug 16 - Thu, Aug 20
Allegiant Air Logo
9:42 pm - 8:18 pm
EYW
-
TYS
22h 36m
1 stop
Allegiant Air Logo
11:35 am - 4:19 pm
TYS
-
EYW
4h 44m
1 stop
$305Allegiant Air
Thu, Dec 10 - Mon, Dec 14
American Airlines Logo
8:00 am - 2:29 pm
EYW
-
TYS
6h 29m
1 stop
American Airlines Logo
2:55 pm - 9:45 pm
TYS
-
EYW
6h 50m
1 stop
$319American Airlines
Fri, Sep 4 - Mon, Sep 7
American Airlines Logo
1:50 pm - 8:59 pm
EYW
-
TYS
7h 09m
1 stop
American Airlines Logo
6:06 am - 10:56 am
TYS
-
EYW
4h 50m
1 stop
$339American Airlines
Fri, Sep 18 - Mon, Sep 21
Delta Logo
6:19 pm - 11:55 pm
EYW
-
TYS
5h 36m
1 stop
Delta Logo
2:08 pm - 8:00 pm
TYS
-
EYW
5h 52m
1 stop
$339Delta
Fri, Sep 4 - Mon, Sep 7
American Airlines Logo
4:50 pm - 10:58 pm
EYW
-
TYS
6h 08m
1 stop
American Airlines Logo
6:06 am - 1:05 pm
TYS
-
EYW
6h 59m
1 stop
$339American Airlines
Tue, Nov 24 - Sat, Nov 28
Delta Logo
6:00 am - 11:29 am
MIA
-
TYS
5h 29m
1 stop
Delta Logo
7:21 pm - 12:59 am
TYS
-
MIA
5h 38m
1 stop
$401Delta
Sat, Nov 21 - Wed, Nov 25
Delta Logo
6:00 am - 11:29 am
MIA
-
TYS
5h 29m
1 stop
Delta Logo
2:40 pm - 8:59 pm
TYS
-
MIA
6h 19m
1 stop
$401Delta
Useful Info

Good to know

Low season

January

Cheapest flight

$65
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly with an average 2% increase in price.
Flight from Key West to Knoxville

FAQs for booking flights from Florida Keys to Knoxville

  • How does KAYAK find such low prices on flights from Florida Keys to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Florida Keys to Knoxville

 
Need help choosing which airline to fly with from Florida Keys to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8492 reviews
7.2Food
8.1Boarding
8.5Crew
7.8Entertainment
7.8Comfort
Airline reviews

Internet didn’t work for this leg either. The seat was fine but didn’t have seatback screen, which I knew when I booked it. The biggest letdown is Deltas new policy on beverage/snack service not being served for flights less than 350 miles. I know this is a cost cutting measure, but how much does it really cost to give a drink and a snack for inflated airfare? I really am surprised that with Delta Comfort they don’t provide beverage/snack service given these seats cost extra to purchase. Really need to reconsider this, even if it’s for the Delta Comfort and above.

6.0 GoodLane, Jul 2026
ATL - MEM
Read more Delta reviews

Internet didn’t work for this leg either. The seat was fine but didn’t have seatback screen, which I knew when I booked it. The biggest letdown is Deltas new policy on beverage/snack service not being served for flights less than 350 miles. I know this is a cost cutting measure, but how much does it really cost to give a drink and a snack for inflated airfare? I really am surprised that with Delta Comfort they don’t provide beverage/snack service given these seats cost extra to purchase. Really need to reconsider this, even if it’s for the Delta Comfort and above.

The flights are constantly late anymore, and they won't even give you a glass of water on the plane. For years, they were able to do a service on this flight from Atlanta to Knoxville and Knoxville Atlanta now they say it's too short of a flight. You can't even get a quick drink of water.

Should never have had to go to Detroit from Orlando back to Tennessee!

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Same experience as the flight from Norfolk to Atlanta where people are boarded in zones that don't make sense. People behind you on the plane will get on before you and they take the luggage space on your row.

Smallest leg room I've ever had on a plane.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

Kind staff. Snacks are small but that’s the new normal.

Very frustrated with boarding gate crew. She announced the plane was small and they would be limiting us to one item to carry on. Not a problem for me as I understand the tiny planes have limited space!! Not the case here! It was a rather large plane and had plenty of room for bags! So because I don’t want to be one of “those people” who ignores the request to check a carry on I did so asking if I would be able to pick it up at the bottom of the ramp on arrival in Knoxville to which she responded “yes”! Then I watched as every other passenger held onto their 2 items and boarded!! Then when we arrived in Knoxville our 2 carry ons had been put with all the other luggage and we had to go to baggage pick up and wait for all the big checked bags to come off the carousel! So she lied!! Frustrating. Next time I won’t be so nice!

Flight was great. DELTA did a fantastic job! ATL was busy, as usual!

This is a no frills, get it done, efficient airline. The seat is a lawn chair. You better bring your own entertainment. If you want something other than water you need to pay for it. But they will get you to your destination quickly, on time, and then they will turn the flight around and go right back where they came from. Reliably. Couple times a week tops. If it fits into your schedule, you can’t get there cheaper or faster.

Allegiant actually impressed me, original inbound flight from PBG was so late they gave us a bird inbound from Des Moines and only left 1h late and gained 40 minutes back in the air. Comfortable flight with no frills but no complaints.

Flight was delayed. Crew was good but hot coffee was not available.

It was cold on the flight. The crew was very pleasant. I didn't order any food. We were delayed due to Captain waiting on maintenance log. He kept us informed though. The flight itself was smooth. I would definitely fly with Allegiant again!

Superb. Staff great. Great flight. As with other airlines, seating too tight and restrictive.

WE were delayed about an hour and never any communications from the employees working the gate. We also were moved to a total of three gates.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Flight was good, boarding was a breeze, flight attendants were friendly and professional. There was a medical issue with another passenger and the crew handled it in a calm and professional way.

Great seat space. However food and drink prices outrageous. Jabbing to pay for a carry on bag or stuck paying at the gate too much.

desk agent in sioux falls is rough .needs customer courtesy training

The flight was delayed almost three hours. I understand delays happen from time to time, but this flight was delayed no less than 10 times. I wish the amount of time of the delay was more accurate, versus delaying in 10 or 20 minute increments many, many times.

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

Delays experienced in boarding/take off due to incoming plane delayed. However, the boarding time/depart time in the app was significantly delayed in providing these updates. Usually not updated until an hour after we should have already boarded. Poorly managed.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

At least it was a short flight. Greyhound with wings.

I never have a good experience with American and this was no different. The airplane was INCREDIBLY hot. Like unbearably so. Everyone was fanning themselves with pamphlets and sweating. When someone asked the flight attendant to turn down the temperature they were told there was nothing the crew could do. Once we pushed back from the gate we then had to wait an hour to take off and the communication from the crew was not good. People were getting up this whole time and a man was even in the bathroom when we took off. Once we landed at our destination we waited another 30 minutes at the gate to deplane with, again, no communication from the crew as to what was going on.

I had purchased a ticket that allowed one check bag yet I was still charged for my bag! the lady at the ticket counter was rude and condescending.

The flights was good, but could have more option to buy foods with it being a three and a half hours flights

Our flight got changed and/or delayed 8 times before we boarded.

On time. No problems boarding. AA checked my roller bag for free. In flight entertainment wasn’t really working and they didn’t sell the snacks on the paper menu.

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