TYS

$65 Find Cheap Flights from Florida Keys to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Knoxville departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Everything you should know

Cheapest round-trip
$159
Overall average: $407
American Airlines
Thu 12/4Mon 12/8
MIA - TYS • Non-stop
Cheapest one-way
$65
Allegiant Air
Fri 11/14
EYW - TYS • Non-stop
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Flight Deals

Cheap Flights from Florida Keys to Knoxville

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Florida Keys to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Florida Keys to Knoxville

Thu, Dec 4 - Mon, Dec 8
American Airlines Logo
9:34 pm - 11:57 pmMIA-TYS
2h 23mnonstop
American Airlines Logo
6:00 am - 8:17 amTYS-MIA
2h 17mnonstop
$159American Airlines
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Thu, Dec 4 - Sun, Dec 7
American Airlines Logo
2:14 pm - 4:33 pmMIA-TYS
2h 19mnonstop
American Airlines Logo
5:03 pm - 7:20 pmTYS-MIA
2h 17mnonstop
$161American Airlines
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Thu, Jan 8 - Sun, Jan 11
American Airlines Logo
9:34 pm - 11:59 pmMIA-TYS
2h 25mnonstop
American Airlines Logo
6:20 am - 8:38 amTYS-MIA
2h 18mnonstop
$179American Airlines
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Fri, Nov 14 - Mon, Nov 17
Multiple Airlines Logo
11:31 am - 10:56 pmMIA-TYS
11h 25m1 stop
Multiple Airlines Logo
2:22 pm - 12:34 amTYS-MIA
10h 12m2 stops
$186Multiple Airlines
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Thu, Nov 13 - Mon, Nov 17
Multiple Airlines Logo
6:00 am - 6:22 pmMIA-TYS
12h 22m1 stop
Multiple Airlines Logo
2:22 pm - 12:29 pmTYS-MIA
46h 07m2 stops
$209Multiple Airlines
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Thu, Oct 30 - Thu, Nov 6
Frontier Logo
6:00 am - 6:22 pmMIA-TYS
12h 22m1 stop
Frontier Logo
7:17 pm - 6:19 amTYS-MIA
11h 02m1 stop
$217Frontier
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Tue, Oct 28 - Wed, Nov 5
Delta Logo
4:35 pm - 11:07 pmMIA-TYS
6h 32m1 stop
Delta Logo
11:44 am - 6:20 pmTYS-MIA
6h 36m1 stop
$224Delta
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Sat, Feb 21 - Wed, Feb 25
Delta Logo
7:00 am - 1:26 pmMIA-TYS
6h 26m1 stop
Delta Logo
6:10 am - 2:48 pmTYS-MIA
8h 38m1 stop
$229Delta
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Thu, Oct 30 - Sun, Nov 2
Frontier Logo
6:00 am - 6:22 pmMIA-TYS
12h 22m1 stop
Frontier Logo
7:02 pm - 6:19 amTYS-MIA
11h 17m1 stop
$254Frontier
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Wed, Oct 29 - Sun, Nov 2
Allegiant Air Logo
10:02 am - 9:05 pmEYW-TYS
11h 03m1 stop
Allegiant Air Logo
12:28 pm - 7:43 pmTYS-EYW
7h 15m1 stop
$435Allegiant Air
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Good to know

Low seasonJanuary
Cheapest flight$65
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from Key West to Knoxville

FAQs for booking flights from Florida Keys to Knoxville

  • How does KAYAK find such low prices on flights from Florida Keys to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Florida Keys to Knoxville

 
Need help choosing which airline to fly with from Florida Keys to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7984 reviews
8.5Crew
7.9Comfort
7.9Entertainment
7.3Food
8.2Boarding
Airline reviews

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

10.0 ExcellentAnonymous, Oct 2025EYW - ATL
Read more Delta reviews

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

Kind staff. Snacks are small but that’s the new normal.

We had 3 flights. 1 & 2 were on the same plane but we had to de-board just to re-board 30 mins later. That may have been due to a crew change though. Our 3rd flight had a couple “maintenance” issues that held us up. They were quickly resolved but it took forever for someone to bring the paperwork needed so we could leave. Apparently there was a computer glitch so a driver had to bring a physical copy. It delayed us about 1 1/2 hrs. The flights themselves were smooth & no problems. For boarding, I don’t know why they don’t start with the back of the plane & move forward. It would eliminate the back up from people trying to find their seats & put their bags in the overhead bins. Unless you’re on an overseas flight, there is no food, you get a beverage & either a small bag of pretzels or a biscuit cookie. Take your own food or snacks of you want something more.

Lost bag and 2 days no word leaving for cruise no clothes or stuff

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Food was ok, but not as good as I have had before on AA.

Pretty good. The food was just mediocre, the boarding and crew were good.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

The crew was great and the flight was very smooth. Can’t really judge food since I did not get any because it costs money. The seat was comfortable for what we bought. Thanks!

Crew was great. No entertainment and food and beverage was for purchase only, even water

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

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