TYS

$80 Find Cheap Flights from Florida Keys to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Knoxville departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$153
Allegiant Air
Fri 5/8Mon 5/18
EYW - TYS • Non-stop
Cheapest one-way
$80
Typical prices: $463-$585
Frontier
Mon 3/2
MIA - TYS • 1 stop
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Flight Deals
Useful Info
Flight Deals

Cheap Flights from Florida Keys to Knoxville

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Florida Keys to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Florida Keys to Knoxville

Fri, May 8 - Mon, May 18
Allegiant Air Logo
11:01 am - 1:16 pm
EYW
-
TYS
2h 15mnonstop
Allegiant Air Logo
8:00 am - 10:11 am
TYS
-
EYW
2h 11mnonstop
$153Allegiant Air
Mon, Jun 8 - Fri, Jun 12
Allegiant Air Logo
9:01 am - 11:16 am
EYW
-
TYS
2h 15mnonstop
Allegiant Air Logo
7:30 am - 9:41 am
TYS
-
EYW
2h 11mnonstop
$156Allegiant Air
Tue, Apr 14 - Wed, Apr 15
Southwest Logo
12:35 pm - 8:50 pm
MIA
-
TYS
8h 15m
1 stop
Southwest Logo
7:05 am - 12:40 pm
TYS
-
MIA
5h 35m
1 stop
$197Southwest
Tue, Apr 14 - Wed, Apr 15
Southwest Logo
6:15 am - 2:20 pm
MIA
-
TYS
8h 05m
2 stops
Southwest Logo
7:05 am - 12:40 pm
TYS
-
MIA
5h 35m
1 stop
$202Southwest
Thu, Mar 5 - Mon, Mar 9
Multiple Airlines Logo
5:55 pm - 12:00 pm
MIA
-
TYS
18h 05m
1 stop
Multiple Airlines Logo
8:54 pm - 10:34 am
TYS
-
MIA
13h 40m
2 stops
$213Multiple Airlines
Tue, Mar 3 - Tue, Mar 3
Delta Logo
7:15 am - 11:08 am
MIA
-
TYS
3h 53m
1 stop
Delta Logo
5:02 pm - 11:20 pm
TYS
-
MIA
6h 18m
1 stop
$231Delta
Mon, Jun 8 - Fri, Jun 12
Multiple Airlines Logo
12:10 pm - 11:34 pm
EYW
-
TYS
11h 24m
1 stop
Multiple Airlines Logo
7:30 am - 9:41 am
TYS
-
EYW
2h 11mnonstop
$231Multiple Airlines
Wed, Feb 18 - Sat, Feb 21
American Airlines Logo
9:43 pm - 11:59 pm
MIA
-
TYS
2h 16mnonstop
American Airlines Logo
5:00 pm - 11:43 pm
TYS
-
MIA
6h 43m
1 stop
$244American Airlines
Fri, Feb 27 - Mon, Mar 2
Delta Logo
11:33 am - 8:20 pm
MIA
-
TYS
8h 47m
1 stop
Delta Logo
5:02 pm - 11:20 pm
TYS
-
MIA
6h 18m
1 stop
$259Delta
Fri, Feb 13 - Tue, Feb 17
American Airlines Logo
4:40 pm - 9:55 pm
EYW
-
TYS
5h 15m
1 stop
American Airlines Logo
8:50 am - 4:49 pm
TYS
-
EYW
7h 59m
2 stops
$406American Airlines
Useful Info

Good to know

Low seasonJanuary
Cheapest flight$80
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly and prices are also 13% lower on average.
Flight from Miami to Knoxville

FAQs for booking flights from Florida Keys to Knoxville

  • How does KAYAK find such low prices on flights from Florida Keys to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Florida Keys to Knoxville

 
Need help choosing which airline to fly with from Florida Keys to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8130 reviews
7.8Entertainment
7.9Comfort
8.5Crew
7.2Food
8.1Boarding
Airline reviews

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

10.0 ExcellentSteven, Jan 2026
FLL - CVG
Read more Delta reviews

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

No WiFi. Comfort plus should have alcohol provided, crew only offered water or tea. Who the heck wants tea?

I have diamond medallion status and usually we are in comfort plus . We were in main this time ( which was fine ) and my husband wanted wine . I have at least 10 vouchers for drinks that are good for this year and next! The attendant would not take the picture of the voucher as proof and never came back to check as She asked me to pull it up on delta Wi-Fi. Instead my husband just used his Amex to buy the wine . Disappointing!!!

Food is basically Sun Chips, cookies or Cheezits. I had an exit row seat so I had plenty of room. The crew was very nice and efficient. Pilot kept us informed. Pretty good flight.

The only thing nice I can say is the flight crew was really nice and apologetic about the situation. They shared as much information as they had and advised us on what we could do about missing connecting flights. The boarding process was so slow. The gate agent was working by herself and should have had someone working with her. It took almost an hour to board because she was trying to board a full flight of people and provide customer service to everyone who was flying standby and/or had questions. It was really chaotic. This didn't help the fact that we were delayed and folks were missing connections the longer it took.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

Little warm on the plane and delayed for an hour

UGH I HAD TO MISS MY FIRST FLIGHT TO TAMPA CAUSE OF THE 10 MINUTE DELAY OF THE ORLANDO TO MIAMI ONE SO THEY HAD ME GET ANOTHER TICKET. I AM NOT HAPPY AT ALL BECAUSE IT MADE ME MISS MY CONNECTING FLIGHT FROM TAMPA TO LONDON AND FORCED ME TO MISS A DAY AT MY ROOM IN THE UK.

Wish they didnt delay off-boarding for 10 minutes so i could connect to my flight from miami to tampa

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

Boarding was organized and timely. Food was mediocre, especially for first class travel.

We were 4+ hours delayed. AA is absolutely obnoxious. They just kept pushing back the time to the point where we did not get into Vegas until after midnight when we were supposed to arrive like 845pm.

It was fine. Nobody was outstandingly friendly but no one was rude and everything was smooth . The captain thanked us for flying but no one greeted me as I walked on the plane or as I exited which is the least they could do lol

Clean, friendly, roomy. But check-in from the phone link was terrible. Repeated attempts wouldn’t save at the final step. Just kept spinning! It was very frustrating. Finally, I used the app (vs website link) to check-in which worked very smoothly on the first attempt.

Check in on the web portal was cumbersome! After several attempts I finally got the boarding pass.

Excellent flight and even arrived 23 min early. No entertainment , or wi fi on board, but I downloaded a couple of movies beforehand which kept me entertained. Really like flying Allegiant airlines.

WE were delayed about an hour and never any communications from the employees working the gate. We also were moved to a total of three gates.

I love how they show love to their customers and care about them too.

I liked how when I got on board how fast we ended up taking off but what I truly disliked was how uncomfortable the seats were. There was truly never a time that I could ever get comfortable during both of my flights. The seats could get away during shorter flights but flights 3 hour plus makes it hard to enjoy.

The crew was great and the flight was very smooth. Can’t really judge food since I did not get any because it costs money. The seat was comfortable for what we bought. Thanks!

Crew was great. No entertainment and food and beverage was for purchase only, even water

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

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