$78 Find Cheap Flights from Knoxville to Indiana - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Indiana departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Knoxville to Indiana

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Indianapolis
Indianapolis2 stops$222
South Bend
South Bend1 stop$223
Chicago
Chicago1 stop$194
Indianapolis
Indianapolis2 stops$222
South Bend
South Bend1 stop$223
Chicago
Chicago1 stop$194

Book Cheap Knoxville to Indiana Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Indiana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Indiana

Wed, Sep 23 - Tue, Sep 29
Multiple Airlines Logo
10:54 am - 2:45 pm
TYS
-
ORD
28h 51m
1 stop
Multiple Airlines Logo
7:11 am - 10:05 am
ORD
-
TYS
25h 54m
1 stop
$194Multiple Airlines
Thu, Aug 13 - Sun, Aug 16
Allegiant Air Logo
1:23 pm - 1:59 pm
TYS
-
MDW
1h 36mnonstop
Allegiant Air Logo
2:49 pm - 5:19 pm
MDW
-
TYS
1h 30mnonstop
$197Allegiant Air
Sun, Aug 9 - Sun, Aug 16
Allegiant Air Logo
1:23 pm - 1:59 pm
TYS
-
MDW
1h 36mnonstop
Allegiant Air Logo
2:49 pm - 5:19 pm
MDW
-
TYS
1h 30mnonstop
$197Allegiant Air
Wed, Sep 2 - Wed, Sep 23
Multiple Airlines Logo
3:46 pm - 12:50 pm
TYS
-
ORD
22h 04m
1 stop
Multiple Airlines Logo
7:11 am - 10:04 am
ORD
-
TYS
25h 53m
1 stop
$207Multiple Airlines
Thu, Oct 1 - Fri, Jan 1
American Airlines Logo
8:15 pm - 9:30 pm
TYS
-
ORD
2h 15mnonstop
American Airlines Logo
8:20 am - 11:05 am
ORD
-
TYS
1h 45mnonstop
$258American Airlines
Wed, Nov 18 - Sat, Nov 21
United Airlines Logo
5:40 pm - 6:43 pm
TYS
-
ORD
2h 03mnonstop
United Airlines Logo
7:07 am - 10:07 am
ORD
-
TYS
2h 00mnonstop
$259United Airlines
Thu, Sep 10 - Sat, Sep 12
United Airlines Logo
1:53 pm - 2:54 pm
TYS
-
ORD
2h 01mnonstop
United Airlines Logo
2:10 pm - 4:58 pm
ORD
-
TYS
1h 48mnonstop
$259United Airlines
Mon, Aug 24 - Mon, Aug 31
American Airlines Logo
6:52 pm - 8:04 pm
TYS
-
ORD
2h 12mnonstop
American Airlines Logo
10:00 am - 12:46 pm
ORD
-
TYS
1h 46mnonstop
$259American Airlines
Tue, Aug 25 - Sat, Aug 29
Delta Logo
6:12 pm - 12:27 am
TYS
-
IND
6h 15m
1 stop
Delta Logo
7:02 am - 12:28 pm
IND
-
TYS
5h 26m
1 stop
$273Delta
Thu, Aug 27 - Thu, Sep 3
Delta Logo
5:40 am - 9:05 am
TYS
-
IND
3h 25m
1 stop
Delta Logo
6:00 am - 9:36 am
IND
-
TYS
3h 36m
1 stop
$273Delta
Booking Insights

KAYAK's insights & trends for Knoxville to Indiana flights

Get data-powered insights and trends into flights from Knoxville to Indiana to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to Indiana?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Indiana departing in August.

Flight prices are below average for this route right now.

Flights to Indiana from Knoxville usually cost between $233 and $248 in August.
The lowest price found in the past 5 days was $222 on Multiple Airlines (Aug 23-Aug 28).

What is the cheapest Knoxville to Indiana flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Indiana from Knoxville found in the last 5 days was to South Bend, at $97 round-trip. The most popular route is from Knoxville (TYS) to South Bend (SBN), and the cheapest round-trip airline ticket found on this route in the last 5 days was $97.

Can I save money by flying with a layover from Knoxville to Indiana?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $227, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Knoxville to Indiana?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Indiana, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Indiana is August, when tickets cost $241 (return) on average. On the other hand, the most expensive months are January and June, when the average cost of round-trip tickets is $801 and $449 respectively.

Good to know

Low season

January

Cheapest flight

$78
Best time to beat the crowds but there is an average 41% increase in price.
Most popular time to fly and prices are also 26% lower on average.
Flight from Knoxville to Chicago Midway Airport

FAQs - booking Indiana flights

  • How does KAYAK find such low prices on flights from Knoxville to Indiana?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Indiana.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Indiana?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to Indiana is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Indiana?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to Indiana with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Indiana?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to Indiana up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to Indiana

  • Looking for a cheap flight? 25% of our users found tickets from Knoxville to the following destinations at these prices or less: Chicago $258 one-way - $333 round-trip

Reviews of the top 3 airlines serving from Knoxville to Indiana

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Indiana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Indiana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8501 reviews
8.1Boarding
8.5Crew
7.8Entertainment
7.2Food
7.8Comfort
Airline reviews

My flight home from Knoxville, TN, included a layover in Atlanta. I boarded the aircraft in Zone 5 and although there was limited overhead space, I was able to put my 'backpack' style roller-bag above my seat. Unfortunately, due to continued bad weather, we had to deplane. There were many people who would have missed their connection, so they rebooked. When we were re-boarding, the gate agent welcomed zone 5 and then made an announcement: All roller-bags for zone 5 passengers and higher will need to be gate checked. I promptly pushed the telescoping handle in and held my bag like a backpack. I was able to bring it on board, which was a relief. Upon entering the aircraft it became apparent that there was easily 40% open overhead space. There were audible signs of angry passengers who felt duped into checking their bags when in fact there were noticeably LESS passengers on the aircraft and TONS of overhead space. I'm not sure what kinds of parameters are used to determine when to cut off roller-bags from being brought on board, but it seemed deceptive and underhanded to have so many people get stuck checking their bags when clearly there was ample room for at least one more zone.

4.0 OkayErnest, Jul 2026
TYS - ATL
Read more Delta reviews

My flight home from Knoxville, TN, included a layover in Atlanta. I boarded the aircraft in Zone 5 and although there was limited overhead space, I was able to put my 'backpack' style roller-bag above my seat. Unfortunately, due to continued bad weather, we had to deplane. There were many people who would have missed their connection, so they rebooked. When we were re-boarding, the gate agent welcomed zone 5 and then made an announcement: All roller-bags for zone 5 passengers and higher will need to be gate checked. I promptly pushed the telescoping handle in and held my bag like a backpack. I was able to bring it on board, which was a relief. Upon entering the aircraft it became apparent that there was easily 40% open overhead space. There were audible signs of angry passengers who felt duped into checking their bags when in fact there were noticeably LESS passengers on the aircraft and TONS of overhead space. I'm not sure what kinds of parameters are used to determine when to cut off roller-bags from being brought on board, but it seemed deceptive and underhanded to have so many people get stuck checking their bags when clearly there was ample room for at least one more zone.

The CRJ-900 was clean but the overhead air vents were broken in our First Class row, making the cabin very hot until about 30 mins into the flight. The flight attendants were both extremely apologetic and accommodating though so that is why I rated the flight as very good. They checked on us many times and truly showed they cared. The snacks for an hour and a half flight could be better. Would be nice if there was a small plated meal over convenient store snacks. WiFi also was not working. And it would be nice if Delta had adjustable headrests on these planes.

I was in Comfort and we didn’t get any drinks, chips or anything! First Class got full service on the flight and Comfort got nothing. Seat was horrible and uncomfortable

Two delays on two separate planes with parts they could not easily find and replace.

Short trip, no food and therefore no expectation for much interaction with staff who were pleasant and professional. My critique is on comfort of the seats. Exit rows and comfort seats do not provide enough personal space for 3 side-by-side seats, especially when in the middle row. Some passengers are not considerate of the middle seat and there should be signs that state something to the effect of: "please consider giving middle seats use of the armrests."

The tray table was broken and the food was terrible.

No entertainment. Plane was so small had to pink tag a carry on ive used for 20 years easily on board. The fact the flight got in at midnight, had to wait for crew in fort wayne to allow the plane to approach the gate, THEN had to wait for bag on jet bridge made experience irritating at best.

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

No WiFi. Arrival was early but gate was occupied and had to sit on jet 30 min to deplane.

From Atlanta to Cabo I would have hoped on a plane that size I would have been able to breathe and wiggle my feet a little! The leg room in that plane is non existent and I am only 5”4’. And the air vent either wasn’t working very well or just could not blow air from the ceiling to the seat area as I was suffocating through the entire flight! And please don’t say I would have been more comfortable in first class because I cannot afford those rates and have always travelled Main Cabin without issues !

Onboard staff was courteous, helpful, responsive and friendly. The boarding process was disorganized, poorly communicated, and disheveled. Gate agents were yelling instead of using the PA system, didn’t communicate the timing delay of our flight, and created an atmosphere of chaos rather than order and communication. As far as I know, there was no reason for their. I would hate to see how it operated under extreme conditions. I’ve never seen United Airlines operations in such a state.

It was extremely hot in the cabin the entire flight, vent air was worn

The head rest is too big and cannot be placed differently/removed. Causes one head to tilt forward and increase back pain

Our flight to Rome, Italy was cancelled the day of and we were never informed. We only found out because I was trying to get into my husbands account and called to get his account number. Had to pay more for worse seating on another airline.

I wish there were outlets to charge my iPhone. The crew was great; we had a female pilot who was great with explaining what was happening and delays,

The staff was hospitable and professional. The seat had a bit of wear. The winner shade was stuck 1/4 open. I received the best of both worlds. The morning sun was able to come in and blind the screen i was trying to use while at the same time it was too low to look out and enjoy the view. Rather embarrassing for a 1st class ticket.

Even though we were delayed, we were able to make our connection

Another delayed flight. When the delays exceed the duration of the flight, it’s a problem.

Trip was great. A wild landing in Ottawa with the wind and rain, but the pilot did a great job. Always love flying United.👍

Flight was on time. Staff were friendly. I paid for Economy Plus but was required to check my standard carry-on luggage due to lack of space on the aircraft. This cost me 30 minutes, unexpectedly, in waiting at the baggage claim. This experience did not meet my expectations.

How is it that every American flight from DFW to IND is significantly delayed? This is the third time in two months I have been delayed flying out of DFW - ALWAYS for a maintenance issue. Makes me want to drop flying American altogether…or maybe flying through Dallas. Miserable experience.

Pilots were fantastic - super smooth. First Class flight attendant was very attentive. Main Cabin flight attendant should try to smooth the rough edges of her voice - very shrill / punitive. Hurt my ears just to listen to her. Recognize they have a (tough) job to do - but tone over speakers needs to be less like scolding a 5 year old.

Delayed and horrible communication and sat on flight for an hour before taking off

Not to have gotten delayed by 2+ hours for the fourth straight American flight. They're the worst.

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

I didn’t like anything, being platinum pro get you absolutely nowhere and does not increase the customer service treatment whatsoever anymore. My flight was canceled and they put me on a flight eight hours later that would’ve got me back in the middle of the night. They could’ve easily move me up to an hour Prior on an earlier flight. My second flight was unreasonable to take, the third flight was also canceled due to mechanical issues like the first flight. I don’t know what’s going on with American, but they are falling apart, after seven flight changes I finally got home, Unreasonable.

This was a horrible American Airlines experience, and it discourages me from flying with them again. It may have stemmed from a mechanical delay, but it appeared that the team was unprepared to respond to the delay. After boarding, we waited an hour before finally taking off. After landing at our destination, we waited an additional hour on the tarmac waiting for a gate (at 8:00pm) to be assigned and cleared. The flight crew did their best, but they were clearly tired and also ready to be done for the day. Because of the delay, I missed a connecting flight. It was a very poor experience.

Fantastic! If it had not been for a check-in agent in Knoxville I may have not gotten my passes on British Airways. I couldn’t check-in online because British Airways had messed us the info on my tickets to London & Inverness. AA’s was great! British Airways was a continuous series of delays and frustrations.

Wheelchair was waiting for me,changed to a better seat which was great as it's hard for me to walk

Everything you need to know for your flight from Knoxville to Indiana

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