TYS - MFR

$353 Find Cheap Flights from Knoxville to Medford

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Medford departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Medford

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Medford, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Medford, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$394
Delta
Wed 8/12Thu 8/20
TYS - MFR • 2 stops
Cheapest one-way
$353
United Airlines
Thu 4/23
TYS - MFR • 1 stop
Top airlines
Delta
Cheapest • from $394 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Medford. You'll need at least 1 connection.
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Medford (TYS-MFR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Medford that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Medford

Wed, Aug 12 - Thu, Aug 20
Delta Logo
6:15 pm - 11:41 pm
TYS
-
MFR
8h 26m
2 stops
Delta Logo
5:21 pm - 10:10 am
MFR
-
TYS
13h 49m
2 stops
$394Delta
Fri, May 1 - Fri, May 8
Delta Logo
5:24 pm - 11:52 pm
TYS
-
MFR
9h 28m
2 stops
Delta Logo
5:25 pm - 11:11 am
MFR
-
TYS
14h 46m
2 stops
$434Delta
Wed, Aug 12 - Thu, Aug 20
Delta Logo
6:15 pm - 11:41 pm
TYS
-
MFR
8h 26m
2 stops
Delta Logo
5:21 pm - 10:10 am
MFR
-
TYS
13h 49m
2 stops
$459Delta
Fri, May 1 - Fri, May 8
United Airlines Logo
7:00 am - 5:55 pm
TYS
-
MFR
13h 55m
2 stops
United Airlines Logo
5:00 am - 3:17 pm
MFR
-
TYS
7h 17m
1 stop
$464United Airlines
Wed, Aug 12 - Thu, Aug 20
United Airlines Logo
4:25 pm - 9:10 pm
TYS
-
MFR
7h 45m
1 stop
United Airlines Logo
6:34 pm - 2:36 pm
MFR
-
TYS
17h 02m
2 stops
$512United Airlines
Fri, May 1 - Fri, May 8
United Airlines Logo
7:00 am - 5:55 pm
TYS
-
MFR
13h 55m
2 stops
United Airlines Logo
12:52 pm - 3:17 pm
MFR
-
TYS
23h 25m
1 stop
$518United Airlines
Wed, Aug 12 - Thu, Aug 20
United Airlines Logo
10:16 am - 11:09 pm
TYS
-
MFR
15h 53m
2 stops
United Airlines Logo
2:03 pm - 2:36 pm
MFR
-
TYS
21h 33m
3 stops
$523United Airlines
Wed, Aug 12 - Thu, Aug 20
United Airlines Logo
8:45 am - 1:09 pm
TYS
-
MFR
7h 24m
1 stop
United Airlines Logo
12:45 pm - 10:20 pm
MFR
-
TYS
6h 35m
1 stop
$532United Airlines
Wed, May 20 - Sun, May 24
United Airlines Logo
4:20 pm - 9:31 pm
TYS
-
MFR
8h 11m
1 stop
United Airlines Logo
5:00 am - 8:34 pm
MFR
-
TYS
12h 34m
2 stops
$537United Airlines
Wed, Aug 12 - Thu, Aug 20
United Airlines Logo
2:00 pm - 11:09 pm
TYS
-
MFR
12h 09m
2 stops
United Airlines Logo
2:03 pm - 2:36 pm
MFR
-
TYS
21h 33m
3 stops
$548United Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Medford flights

Get data-powered insights and trends into flights from Knoxville to Medford to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Medford?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Medford were found on Delta ($394) and United Airlines ($464).

Good to know

Cheapest flight$353
Flight from Knoxville to Medford

When to book flights from Knoxville to Medford

Are your dates flexible? Find out the best times to travel from Knoxville to Medford based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Medford

  • What is the cheapest flight from Knoxville to Medford?

    In the last 3 days, the lowest price for a flight from Knoxville to Medford was $353 for a one-way ticket and $394 for a round-trip.

  • Do I need a passport to fly between Knoxville and Medford?

    No

  • Which aircraft models fly most regularly from Knoxville to Medford?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Medford?

    Star Alliance is the only airline alliance operating flights between Knoxville and Medford.

  • How does KAYAK find such low prices on flights from Knoxville to Medford?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Medford.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Medford?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Medford from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Medford?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Medford with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MFR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Medford?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Medford from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Medford

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Medford. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Medford? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9344 reviews
7.1Entertainment
7.7Boarding
6.6Food
8.1Crew
7.3Comfort
Airline reviews

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

10.0 ExcellentAnonymous, Feb 2026
DEN - RSW
Read more United Airlines reviews

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

Wonderful. Quick boarding. Early departure and we arrived 30 minutes early at our destination. Unfortunately, when you arrive early, there is still a departing aircraft at our gate. We had to park for 30 minutes until the gate was clear. So our early arrival was not really early at the gate. Otherwise it was a quick and smooth flight. Appreciated the efficiency.

Everything was great except for the boarding process. Everyone is lining up all at the same time and it’s hard to tell between the groups as they are way too large.

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

it was a very short flight so my expectations were low.

As great a red-eye flight as red-eye flights can be.

Very old flight - time to retire it for newer airplanes

Everything you need to know for your flight from Knoxville to Medford

Information on your arrival and departure airports