Which airports can I use when flying from Knoxville to Medford?

Flights from Knoxville to Medford usually depart from Knoxville McGhee Tyson (TYS) and arrive at Medford (MFR).

What cabin classes can I book on flights from Knoxville to Medford?

Only Economy Class is available on flights from Knoxville to Medford.

Which airports do connecting flights from Knoxville to Medford pass through?

Most connecting flights from Knoxville to Medford pass through Denver Intl (DEN), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.

Can I save money by using flexible dates for flights from Knoxville to Medford?

Yes. Being flexible with your travel dates can save you up to 57% on the Knoxville to Medford route. Friday is the cheapest departure day at $476 round-trip on average, while Tuesday is the most expensive at $1,090, a difference of $614. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Knoxville to Medford?

A nonstop flight from Knoxville to Medford takes 0h 00m, covering 2,113 miles.

Do I need a passport to fly from Knoxville to Medford?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from Knoxville to Medford changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $372 to $1,862. That means the highest observed fare was about 5x higher than the lowest one.

How are flight prices from Knoxville to Medford looking right now?

One-way fares from Knoxville to Medford are currently lower than usual. Average one-way flight prices are about $386, which is 10% below the typical average for this route.

What is the time difference between Knoxville and Medford?

Medford is 3 hours behind Knoxville (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Medford Airport (MFR)?

Medford Airport (MFR) hosts 5 major car rental companies, with daily rates starting from around $27 for economy cars. Top options include: · Budget · Alamo · Dollar · Enterprise Rent-A-Car · Avis

How much should I expect to pay for a Knoxville to Medford flight?

Round-trip flights from Knoxville to Medford range from $381 to $889, with an average of $709 over the past 12 months. Anything below $381 counts as a good deal.

What is the cheapest airline to fly from Knoxville to Medford?

United Airlines ($372) and Delta ($377) are the cheapest airlines to fly round-trip from Knoxville to Medford according to KAYAK data over the last 5 days.

What is the cheapest layover airport when flying from Knoxville to Medford?

Flights via Denver Intl (DEN) offer the most affordable fares, with an average round-trip price of $734. Based on KAYAK data over the past 3 months.

When flying from Knoxville to Medford which airport offers the shortest layover?

Denver Intl (DEN) had the shortest average connection time for Knoxville to Medford layovers at 253 minutes over the past 3 months.

$272 CHEAP FLIGHTS from Knoxville to Medford (TYS - MFR)

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$372

Typical prices: $381-$889

United Airlines

Sun 10/21Wed 10/24

TYS - MFR • 2 stops

Cheapest one-way

$272

Typical prices: $373-$542

Multiple Airlines

Wed 9/19

TYS - MFR • 3 stops

Nonstop flights

Not available

There are currently no direct flights between Knoxville and Medford. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

August

Cheapest • 49% price drop

July

Most popular

Good to know

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We hope you love your trip to Medford!

Flight Deals

Cheap Flights from Knoxville to Medford (TYS-MFR)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Knoxville to Medford

Wed, Oct 21 - Sat, Oct 24

7:15 am - 6:08 pmTYS Knoxville McGhee Tyson-MFR Medford

13h 53m2 stops Houston George Bush Intcntl San Francisco

1:01 pm - 10:13 pmMFR Medford-TYS Knoxville McGhee Tyson

6h 12m1 stop Denver Intl

$372United Airlines

Wed, Oct 21 - Sat, Oct 24

11:45 am - 11:18 pmTYS Knoxville McGhee Tyson-MFR Medford

14h 33m2 stops Detroit Metropolitan Wayne County Seattle/Tacoma Intl

5:25 pm - 10:54 amMFR Medford-TYS Knoxville McGhee Tyson

14h 29m2 stops Seattle/Tacoma Intl Atlanta Hartsfield-Jackson

$377Delta

Thu, Jan 21 - Mon, Jan 25

4:25 pm - 9:10 pmTYS Knoxville McGhee Tyson-MFR Medford

7h 45m1 stop Denver Intl

12:45 pm - 10:20 pmMFR Medford-TYS Knoxville McGhee Tyson

6h 35m1 stop Denver Intl

$379United Airlines

Fri, Oct 23 - Tue, Oct 27

2:38 pm - 11:18 pmTYS Knoxville McGhee Tyson-MFR Medford

11h 40m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl

6:11 am - 9:37 pmMFR Medford-TYS Knoxville McGhee Tyson

12h 26m2 stops Seattle/Tacoma Intl Detroit Metropolitan Wayne County

$383Delta

Fri, Oct 23 - Tue, Oct 27

2:38 pm - 11:55 pmTYS Knoxville McGhee Tyson-MFR Medford

12h 17m2 stops Atlanta Hartsfield-Jackson Salt Lake City

6:11 am - 9:37 pmMFR Medford-TYS Knoxville McGhee Tyson

12h 26m2 stops Seattle/Tacoma Intl Detroit Metropolitan Wayne County

$383Delta

Fri, Oct 23 - Tue, Oct 27

5:40 am - 12:40 pmTYS Knoxville McGhee Tyson-MFR Medford

10h 00m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl

5:25 pm - 9:34 amMFR Medford-TYS Knoxville McGhee Tyson

13h 09m2 stops Seattle/Tacoma Intl Atlanta Hartsfield-Jackson

$383Delta

Thu, Jan 21 - Mon, Jan 25

4:25 pm - 9:10 pmTYS Knoxville McGhee Tyson-MFR Medford

7h 45m1 stop Denver Intl

6:34 pm - 9:59 amMFR Medford-TYS Knoxville McGhee Tyson

12h 25m2 stops San Francisco Chicago O'Hare Intl

$384United Airlines

Thu, Jan 21 - Mon, Jan 25

5:30 am - 12:36 pmTYS Knoxville McGhee Tyson-MFR Medford

10h 06m2 stops Atlanta Hartsfield-Jackson Salt Lake City

6:05 am - 11:46 pmMFR Medford-TYS Knoxville McGhee Tyson

14h 41m2 stops Seattle/Tacoma Intl Atlanta Hartsfield-Jackson

$389Delta

Wed, Oct 21 - Sat, Oct 24

4:53 pm - 9:14 pmTYS Knoxville McGhee Tyson-MFR Medford

7h 21m1 stop Denver Intl

5:00 am - 3:54 pmMFR Medford-TYS Knoxville McGhee Tyson

7h 54m1 stop Denver Intl

$413United Airlines

Tue, Sep 22 - Tue, Sep 29

4:50 pm - 9:08 pmTYS Knoxville McGhee Tyson-MFR Medford

7h 18m1 stop Denver Intl

5:00 am - 3:49 pmMFR Medford-TYS Knoxville McGhee Tyson

7h 49m1 stop Denver Intl

$451United Airlines

Recent last minute flight deals from Knoxville to Medford

Fri, Aug 28 - Sat, Sep 5

6:35 am - 4:48 pmTYS Knoxville McGhee Tyson-MFR Medford

13h 13m2 stops Minneapolis St Paul Seattle/Tacoma Intl

7:15 am - 11:00 pmMFR Medford-TYS Knoxville McGhee Tyson

12h 45m2 stops Salt Lake City Minneapolis St Paul

$559Delta

Fri, Aug 28 - Sat, Sep 5

5:40 am - 4:48 pmTYS Knoxville McGhee Tyson-MFR Medford

14h 08m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl

6:15 am - 7:26 pmMFR Medford-TYS Knoxville McGhee Tyson

10h 11m2 stops Seattle/Tacoma Intl Detroit Metropolitan Wayne County

$597Delta

Fri, Aug 28 - Sat, Sep 5

7:15 am - 4:48 pmTYS Knoxville McGhee Tyson-MFR Medford

12h 33m2 stops Detroit Metropolitan Wayne County Seattle/Tacoma Intl

7:15 am - 11:00 pmMFR Medford-TYS Knoxville McGhee Tyson

12h 45m2 stops Salt Lake City Minneapolis St Paul

$597Delta

Fri, Aug 28 - Sat, Sep 5

7:30 am - 4:48 pmTYS Knoxville McGhee Tyson-MFR Medford

12h 18m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl

7:15 am - 10:39 pmMFR Medford-TYS Knoxville McGhee Tyson

12h 24m2 stops Salt Lake City Atlanta Hartsfield-Jackson

$597Delta

Fri, Aug 28 - Sat, Sep 5

6:35 am - 4:48 pmTYS Knoxville McGhee Tyson-MFR Medford

13h 13m2 stops Minneapolis St Paul Seattle/Tacoma Intl

7:15 am - 10:39 pmMFR Medford-TYS Knoxville McGhee Tyson

12h 24m2 stops Salt Lake City Atlanta Hartsfield-Jackson

$597Delta

Fri, Aug 28 - Sat, Sep 5

9:00 am - 1:01 pmTYS Knoxville McGhee Tyson-MFR Medford

7h 01m1 stop Denver Intl

5:00 am - 3:46 pmMFR Medford-TYS Knoxville McGhee Tyson

7h 46m1 stop Denver Intl

$659United Airlines

Fri, Aug 28 - Sat, Sep 5

4:50 pm - 9:08 pmTYS Knoxville McGhee Tyson-MFR Medford

7h 18m1 stop Denver Intl

6:00 am - 9:45 pmMFR Medford-TYS Knoxville McGhee Tyson

12h 45m2 stops San Francisco Houston George Bush Intcntl

$664United Airlines

Fri, Aug 28 - Sat, Sep 5

9:00 am - 1:01 pmTYS Knoxville McGhee Tyson-MFR Medford

7h 01m1 stop Denver Intl

5:00 am - 3:46 pmMFR Medford-TYS Knoxville McGhee Tyson

7h 46m1 stop Denver Intl

$697United Airlines

Fri, Aug 28 - Sat, Sep 5

1:53 pm - 10:45 pmTYS Knoxville McGhee Tyson-MFR Medford

11h 52m2 stops Chicago O'Hare Intl San Francisco

1:00 pm - 10:29 pmMFR Medford-TYS Knoxville McGhee Tyson

6h 29m1 stop Denver Intl

$702United Airlines

Fri, Aug 28 - Sat, Sep 5

4:50 pm - 9:08 pmTYS Knoxville McGhee Tyson-MFR Medford

7h 18m1 stop Denver Intl

6:00 am - 9:45 pmMFR Medford-TYS Knoxville McGhee Tyson

12h 45m2 stops San Francisco Houston George Bush Intcntl

$702United Airlines

Booking Insights

Price, demand and travel trends for Knoxville to Medford flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Knoxville to Medford with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Knoxville to Medford?

Round-trip flights from Knoxville to Medford start at $372. Prices are below average for this route right now, with typical round-trip fares ranging from $381 to $889. The lowest price found in the past 5 days was $372 on United Airlines.

Find deals

Low season	February
High season	July
Cheapest flight	$272

Most popular time to fly with an average 16% increase in price.

Flight from Knoxville to Medford

When to book flights from Knoxville to Medford

Are your dates flexible? Find out the best times to travel from Knoxville to Medford based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from Knoxville to Medford?
Flights from Knoxville to Medford usually depart from Knoxville McGhee Tyson (TYS) and arrive at Medford (MFR).
What cabin classes can I book on flights from Knoxville to Medford?
Only Economy Class is available on flights from Knoxville to Medford.
Which airports do connecting flights from Knoxville to Medford pass through?
Most connecting flights from Knoxville to Medford pass through Denver Intl (DEN), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.
Can I save money by using flexible dates for flights from Knoxville to Medford?
Yes. Being flexible with your travel dates can save you up to 57% on the Knoxville to Medford route. Friday is the cheapest departure day at $476 round-trip on average, while Tuesday is the most expensive at $1,090, a difference of $614. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How long is a flight from Knoxville to Medford?
A nonstop flight from Knoxville to Medford takes 0h 00m, covering 2,113 miles.
Do I need a passport to fly from Knoxville to Medford?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
Have flight prices from Knoxville to Medford changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $372 to $1,862. That means the highest observed fare was about 5x higher than the lowest one.
How are flight prices from Knoxville to Medford looking right now?
One-way fares from Knoxville to Medford are currently lower than usual. Average one-way flight prices are about $386, which is 10% below the typical average for this route.
What is the time difference between Knoxville and Medford?
Medford is 3 hours behind Knoxville (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Medford Airport (MFR)?
Medford Airport (MFR) hosts 5 major car rental companies, with daily rates starting from around $27 for economy cars. Top options include:
· Budget
· Alamo
· Dollar
· Enterprise Rent-A-Car
· Avis
How much should I expect to pay for a Knoxville to Medford flight?
Round-trip flights from Knoxville to Medford range from $381 to $889, with an average of $709 over the past 12 months. Anything below $381 counts as a good deal.

If your dates can be flexible, aim for a Friday departure instead of Tuesday. On this route, Friday flights average $476 - about $614 less than Tuesday (56% savings) based on the last 12 months.
If you can choose when to travel, plan your Knoxville to Medford trip for August. Fares historically average $364 round-trip in that month - typically $959 less than the most expensive month, which is December (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Medford Airport.
- Candlewood Suites Medford By IHG
- Executive Residency by Best Western Medford
- Quality Inn and Suites Medford Airport

Everything you need to know for your flight from Knoxville to Medford

Airports

Cabin class

Complete your trip

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Information on your arrival and departure airports

Knoxville (TYS)

Medford (MFR)

TYS - MFR

$272 Find Cheap Flights from Knoxville to Medford - Compare and Save

Everything you should know

Cheap Flights from Knoxville to Medford (TYS-MFR)

Recent round-trip flight deals from Knoxville to Medford

Recent one-way flight deals from Knoxville to Medford

Recent last minute flight deals from Knoxville to Medford

Price, demand and travel trends for Knoxville to Medford flights

How much is a round-trip flight from Knoxville to Medford?

What is the cheapest airline to fly from Knoxville to Medford?

What is the cheapest layover airport when flying from Knoxville to Medford?

When flying from Knoxville to Medford which airport offers the shortest layover?

Key details for Knoxville to Medford flights

Low season

High season

Cheapest flight

When to book flights from Knoxville to Medford

Your Knoxville to Medford flight questions, answered

Your guide to booking Knoxville to Medford flights

Everything you need to know for your flight from Knoxville to Medford

Information on your arrival and departure airports

Cabin class types available on flights from Knoxville to Medford

Complete your trip to Medford with a hotel stay or car rental

Find direct flights to and from Knoxville and Medford

Flights to other popular destinations

Flights from domestic origins to Medford

Choose which airport to fly into in Medford

Find deals for your return flight