TYS - MFR

$300 Find Cheap Flights from Knoxville to Medford

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Medford departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Medford

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Medford, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Medford, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$328
Delta
Sat 2/7Tue 2/10
TYS - MFR • 2 stops
Cheapest one-way
$300
American Airlines
Sat 2/14
TYS - MFR • 2 stops
Top airlines
Delta
Cheapest • from $334 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Medford!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Medford (TYS-MFR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Medford that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Medford

Sat, Feb 7 - Tue, Feb 10
Delta Logo
5:40 am - 1:28 pm
TYS
-
MFR
10h 48m2 stops
Delta Logo
5:05 am - 8:47 pm
MFR
-
TYS
12h 42m2 stops
$328Delta
Mon, Feb 2 - Wed, Feb 11
Delta Logo
2:37 pm - 11:48 pm
TYS
-
MFR
12h 11m2 stops
Delta Logo
5:05 am - 8:47 pm
MFR
-
TYS
12h 42m2 stops
$334Delta
Sat, May 2 - Mon, May 4
United Airlines Logo
4:25 pm - 9:10 pm
TYS
-
MFR
7h 45m1 stop
United Airlines Logo
6:34 pm - 10:08 am
MFR
-
TYS
12h 34m2 stops
$345United Airlines
Fri, May 1 - Mon, May 4
United Airlines Logo
4:25 pm - 9:10 pm
TYS
-
MFR
7h 45m1 stop
United Airlines Logo
6:34 pm - 10:08 am
MFR
-
TYS
12h 34m2 stops
$347United Airlines
Sat, May 2 - Mon, May 4
United Airlines Logo
4:25 pm - 9:10 pm
TYS
-
MFR
7h 45m1 stop
United Airlines Logo
12:45 pm - 10:23 pm
MFR
-
TYS
6h 38m1 stop
$352United Airlines
Fri, May 1 - Mon, May 4
United Airlines Logo
4:25 pm - 9:10 pm
TYS
-
MFR
7h 45m1 stop
United Airlines Logo
12:45 pm - 10:23 pm
MFR
-
TYS
6h 38m1 stop
$355United Airlines
Fri, May 1 - Mon, May 4
Delta Logo
5:30 pm - 11:42 pm
TYS
-
MFR
9h 12m2 stops
Delta Logo
5:28 pm - 11:15 am
MFR
-
TYS
14h 47m2 stops
$365Delta
Wed, Feb 4 - Tue, Feb 10
Delta Logo
7:30 am - 4:40 pm
TYS
-
MFR
12h 10m2 stops
Delta Logo
5:20 pm - 12:13 pm
MFR
-
TYS
15h 53m2 stops
$370Delta
Fri, Jan 23 - Tue, Jan 27
United Airlines Logo
4:25 pm - 9:02 pm
TYS
-
MFR
7h 37m1 stop
United Airlines Logo
12:55 pm - 10:31 pm
MFR
-
TYS
6h 36m1 stop
$389United Airlines
Thu, Jan 22 - Mon, Jan 26
United Airlines Logo
4:25 pm - 9:02 pm
TYS
-
MFR
7h 37m1 stop
United Airlines Logo
6:25 pm - 10:57 am
MFR
-
TYS
13h 32m2 stops
$394United Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Medford flights

Get data-powered insights and trends into flights from Knoxville to Medford to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Medford?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Medford were found on Delta ($334) and United Airlines ($394).

Which airlines fly non-stop between Knoxville and Medford?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Knoxville to Medford.

There is just one airline that flies from Knoxville to Medford direct and that is United Airlines. The best round-trip deal found from United Airlines for the route is $462.

Find deals

Good to know

Low seasonMarch
Cheapest flight$300
Best time to beat the crowds with an average 46% drop in price.
Most popular time to fly with an average 53% increase in price.
Flight from Knoxville to Medford

When to book flights from Knoxville to Medford

Are your dates flexible? Find out the best times to travel from Knoxville to Medford based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Medford

  • What is the cheapest flight from Knoxville to Medford?

    In the last 3 days, the lowest price for a flight from Knoxville to Medford was $300 for a one-way ticket and $328 for a round-trip.

  • Do I need a passport to fly between Knoxville and Medford?

    No

  • Which aircraft models fly most regularly from Knoxville to Medford?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Medford?

    Star Alliance is the only airline alliance operating flights between Knoxville and Medford.

  • How does KAYAK find such low prices on flights from Knoxville to Medford?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Medford.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Medford?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Medford from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Medford?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Medford with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MFR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Medford?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Medford from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Medford

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Medford. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Medford? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9142 reviews
7.7Boarding
8.1Crew
7.3Comfort
6.6Food
7.1Entertainment
Airline reviews

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

4.0 OkayWalter, Jan 2026
CLE - SFO
Read more United Airlines reviews

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Check-in, boarding and the flight from Phoenix to Houston was quick and easy. The flight from Houston to Shreveport was delayed 5 hours. It was frustrating but I think United handled it the best they could.

They lost my luggage, so, not happy. The crew was nice but my suitcases never made it, still trying to find out what happened!

The staff was hospitable and professional. The seat had a bit of wear. The winner shade was stuck 1/4 open. I received the best of both worlds. The morning sun was able to come in and blind the screen i was trying to use while at the same time it was too low to look out and enjoy the view. Rather embarrassing for a 1st class ticket.

Perfect flight. Smooth flight. Arrived 20 minutes early at destination. Excellent service.

The flights were on time which was great give. It was holiday travel season and there’d been some weather issues. The only complaint and this is every time with United is the terrible seat design. The head rest is not built for comfort and having my neck bent forward for a cross country trip reminded me while I try not to take United flights as a rule.

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

The flight was delayed by two de-icings. The seatbelt did not work correctly. It did not stay tight.

Everything was absolutely wonderful from check in to baggage claim. Staff was very professional and sweet. Will definitely recommend United to family and friends.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Everything you need to know for your flight from Knoxville to Medford

Information on your arrival and departure airports

Knoxville (TYS)
Medford (MFR)