TYS - MFR

$256 Find Cheap Flights from Knoxville to Medford - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Medford departing on 8/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$357
United Airlines
Wed 9/9Wed 9/23
TYS - MFR • 1 stop
Cheapest one-way
$256
Multiple Airlines
Sun 8/2
TYS - MFR • 2 stops
Top airlines
United Airlines
Cheapest • from $357 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Medford. You'll need at least 1 connection.
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Flight Deals

Cheap Flights from Knoxville to Medford (TYS-MFR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Medford that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Medford

Wed, Sep 9 - Wed, Sep 23
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
United Airlines Logo
5:00 am - 3:54 pm
MFR
-
TYS
7h 54m
1 stop
$357United Airlines
Wed, Sep 9 - Wed, Sep 23
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
United Airlines Logo
6:28 pm - 9:46 am
MFR
-
TYS
12h 18m
2 stops
$362United Airlines
Wed, Aug 12 - Thu, Aug 20
Delta Logo
7:15 am - 4:48 pm
TYS
-
MFR
12h 33m
2 stops
Delta Logo
5:28 pm - 9:36 am
MFR
-
TYS
13h 08m
2 stops
$373Delta
Thu, Aug 20 - Wed, Aug 26
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
United Airlines Logo
1:00 pm - 10:29 pm
MFR
-
TYS
6h 29m
1 stop
$389United Airlines
Thu, Aug 20 - Tue, Aug 25
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
United Airlines Logo
5:00 am - 3:54 pm
MFR
-
TYS
7h 54m
1 stop
$392United Airlines
Thu, Aug 20 - Tue, Aug 25
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
United Airlines Logo
5:00 am - 8:24 pm
MFR
-
TYS
12h 24m
2 stops
$394United Airlines
Thu, Aug 20 - Tue, Aug 25
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
United Airlines Logo
8:00 am - 11:59 pm
MFR
-
TYS
12h 59m
2 stops
$397United Airlines
Fri, Sep 11 - Mon, Sep 14
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
United Airlines Logo
6:28 pm - 9:57 am
MFR
-
TYS
12h 29m
2 stops
$410United Airlines
Thu, Aug 20 - Wed, Aug 26
Delta Logo
4:38 pm - 11:55 pm
TYS
-
MFR
10h 17m
2 stops
Delta Logo
5:28 pm - 9:36 am
MFR
-
TYS
13h 08m
2 stops
$444Delta
Thu, Aug 20 - Tue, Aug 25
United Airlines Logo
9:00 am - 1:01 pm
TYS
-
MFR
7h 01m
1 stop
United Airlines Logo
5:00 am - 3:54 pm
MFR
-
TYS
7h 54m
1 stop
$449United Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Medford flights

Get data-powered insights and trends into flights from Knoxville to Medford to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Medford?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Knoxville to Medford were found on United Airlines ($357) and Delta ($373).

Find deals

Good to know

Cheapest flight$256
Flight from Knoxville to Medford

When to book flights from Knoxville to Medford

Are your dates flexible? Find out the best times to travel from Knoxville to Medford based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Medford

  • What is the cheapest flight from Knoxville to Medford?

    In the last 5 days, the lowest price for a flight from Knoxville to Medford was $256 for a one-way ticket and $357 for a round-trip.

  • Do I need a passport to fly between Knoxville and Medford?

    No

  • Which aircraft models fly most regularly from Knoxville to Medford?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Medford?

    Star Alliance is the only airline alliance operating flights between Knoxville and Medford.

  • How does KAYAK find such low prices on flights from Knoxville to Medford?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Medford.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Medford?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Medford from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Medford?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Medford with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MFR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Medford?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Medford from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Medford

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Medford. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Medford? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9966 reviews
7.3Comfort
8.1Crew
7.7Boarding
6.7Food
7.1Entertainment
Airline reviews

The head rest is too big and cannot be placed differently/removed. Causes one head to tilt forward and increase back pain

8.0 ExcellentKatiuscia, Jul 2026
TYS - ORD
Read more United Airlines reviews

The head rest is too big and cannot be placed differently/removed. Causes one head to tilt forward and increase back pain

Had a one hour delay due to mechanical issue. I didn’t think I’d be able to make my connecting flight, but they waited for me and greeted me when I arrived to help things run smooth.

Our flight to Rome, Italy was cancelled the day of and we were never informed. We only found out because I was trying to get into my husbands account and called to get his account number. Had to pay more for worse seating on another airline.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Even though we were delayed, we were able to make our connection

I will never book a flight through Cheap fare. They booked me from Portland Main . And would not give me a refund, so I bought 2 tickets one for 299. From Portland Main to ORD. Then I had to buy a ticket from Oregon PDX to ORD that was another 440. So Just so you know they even told me it was there fault but no refund. Bad bussniess. I did inform United but they said they couldn't help me due to the fact I booked through Cheap Tickets. Never again. And I'm spreding the word. I let everyone know at my 50th class reunion

Pilot Erika DeLong made us feel safe and at ease in a frankly scary time to be flying. Her warm smile and greeting and excellent command of the aircraft in foggy bumpy weather helped us all to calm our nerves and get us home safely.

Not enough room between rows and food was gross. $160 baggage charge?! Never again.

East Lounge in Denver was terrible. Turning away active military on orders? Really? Sad.

Clean and plenty of room for handbaggage. Leg room was cramped compared with the 777 from Frankfurt.

Everything you need to know for your flight from Knoxville to Medford

Information on your arrival and departure airports

Knoxville (TYS)
Medford (MFR)