TYS - MFR

$373 Find Cheap Flights from Knoxville to Medford

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Medford departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Medford

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Medford, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Medford, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$373
Delta
Wed 8/12Thu 8/20
TYS - MFR • 2 stops
Top airlines
Delta
Cheapest • from $373 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Medford. You'll need at least 1 connection.
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We hope you love your trip to Medford!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Medford (TYS-MFR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Medford that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Medford

Wed, Aug 12 - Thu, Aug 20
Delta Logo
6:15 pm - 11:55 pm
TYS
-
MFR
8h 40m
2 stops
Delta Logo
6:15 am - 8:10 pm
MFR
-
TYS
10h 55m
2 stops
$373Delta
Wed, Aug 12 - Wed, Aug 19
United Airlines Logo
7:15 am - 5:58 pm
TYS
-
MFR
13h 43m
2 stops
United Airlines Logo
5:00 am - 3:54 pm
MFR
-
TYS
7h 54m
1 stop
$392United Airlines
Wed, Aug 12 - Thu, Aug 20
Delta Logo
7:30 am - 4:49 pm
TYS
-
MFR
12h 19m
2 stops
Delta Logo
6:15 am - 8:10 pm
MFR
-
TYS
10h 55m
2 stops
$398Delta
Wed, Aug 12 - Wed, Aug 19
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
United Airlines Logo
5:00 am - 3:54 pm
MFR
-
TYS
7h 54m
1 stop
$432United Airlines
Wed, Aug 12 - Wed, Aug 19
Delta Logo
6:15 pm - 11:55 pm
TYS
-
MFR
8h 40m
2 stops
Delta Logo
6:15 am - 8:10 pm
MFR
-
TYS
10h 55m
2 stops
$444Delta
Wed, Aug 12 - Thu, Aug 20
United Airlines Logo
7:15 am - 5:58 pm
TYS
-
MFR
13h 43m
2 stops
United Airlines Logo
1:08 pm - 10:29 pm
MFR
-
TYS
6h 21m
1 stop
$478United Airlines
Sun, Aug 2 - Sun, Aug 16
Multiple Airlines Logo
7:00 am - 8:43 pm
TYS
-
MFR
16h 43m
2 stops
Multiple Airlines Logo
9:38 pm - 1:57 pm
MFR
-
TYS
13h 19m
1 stop
$505Multiple Airlines
Tue, Oct 27 - Sat, Oct 31
United Airlines Logo
4:25 pm - 9:10 pm
TYS
-
MFR
7h 45m
1 stop
United Airlines Logo
12:45 pm - 10:20 pm
MFR
-
TYS
6h 35m
1 stop
$513United Airlines
Tue, Oct 27 - Sat, Oct 31
United Airlines Logo
4:25 pm - 9:10 pm
TYS
-
MFR
7h 45m
1 stop
United Airlines Logo
6:34 pm - 11:00 am
MFR
-
TYS
13h 26m
2 stops
$518United Airlines
Wed, Aug 12 - Thu, Aug 20
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
United Airlines Logo
1:08 pm - 10:29 pm
MFR
-
TYS
6h 21m
1 stop
$519United Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Medford flights

Get data-powered insights and trends into flights from Knoxville to Medford to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Medford?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 7 days.

In the past 7 days, the cheapest round-trip tickets from Knoxville to Medford were found on Delta ($373) and United Airlines ($392).

Find deals

Good to know

Cheapest flight$373
Flight from Knoxville to Medford

When to book flights from Knoxville to Medford

Are your dates flexible? Find out the best times to travel from Knoxville to Medford based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Medford

  • What is the cheapest flight from Knoxville to Medford?

    In the last 7 days, the lowest price for a flight from Knoxville to Medford was $373 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Medford?

    No

  • Which aircraft models fly most regularly from Knoxville to Medford?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Medford?

    Star Alliance is the only airline alliance operating flights between Knoxville and Medford.

  • How does KAYAK find such low prices on flights from Knoxville to Medford?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Medford.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Medford?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Medford from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Medford?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Medford with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MFR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Medford?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Medford from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Medford

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Medford. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Medford? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9762 reviews
7.1Entertainment
6.6Food
7.3Comfort
7.7Boarding
8.1Crew
Airline reviews

Flight was delayed but more than 90 minutes. This caused me to miss my available windows for pick-up by a friend. I had to pay $125 for an uber back home from the airport which was an added expense that I had not budgeted for my trip. Staff was friendly.

4.0 OkayAnonymous, May 2026
LAX - RNO
Read more United Airlines reviews

Flight was delayed but more than 90 minutes. This caused me to miss my available windows for pick-up by a friend. I had to pay $125 for an uber back home from the airport which was an added expense that I had not budgeted for my trip. Staff was friendly.

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

Had a one hour delay due to mechanical issue. I didn’t think I’d be able to make my connecting flight, but they waited for me and greeted me when I arrived to help things run smooth.

6 1/2 hours from Tampa to SFO on a Boeing 737. Cramped. No Service. No real food. One pass for coffee at the beginning and a second pass THREE hours later. And check-in in Tampa was nasty even by United standards. And I am at almost TWO million miles on United. It's a non-stop. But terrible service.

MY FAMILY'S LUGGAGE WAS LOST FROM ROME TO BARI. I WAS THE ONLY ONE THAT RECEIVED MY LUGGAGE FROM ROME TO BARI. AFTER DEPLANING IN BARI, WE WASTED A LOT OF TIME AT BAG CLAIMS LOST AND FOUND REPORTING THE CLAIM AND PLEADING FOR THE BAGS TO BE DELIVERED THE NEXT DAY. WE WERE TOLD THAT IT TAKES 3 DAYS MINIMUM TO DELIVER. MY DAUGHTER AND MY GIRLFRIEND NEEDED THEIR PERSONAL THINGS AND WE WERE STAYING 3 HOURS AWAY FROM THE BARI AIRPORT. WE HAD TO DRIVE 3 HOURS TO THE AIRPORT TO COLLECT OUR LOST LUGGAGE THE NEXT DAY. WE ARE NOT HAPPY WITH THE EXPERIENCE

We had a delay, but thankfully I made it to my connection. Overall it went smooth

The flight had a delay but I made it to my connection. Flight was smooth overall

As I wrote earlier, poor planning and/or communication. At least twice, we were told that we would be boarding in less than ten minutes, only to have the flight again delayed at least another hour.

This flight is a quick way to get to Chicago, but a bit expensive.

Our flight to Rome, Italy was cancelled the day of and we were never informed. We only found out because I was trying to get into my husbands account and called to get his account number. Had to pay more for worse seating on another airline.

Everything you need to know for your flight from Knoxville to Medford

Information on your arrival and departure airports

Knoxville (TYS)
Medford (MFR)