TYS - MFR

$393 Find Cheap Flights from Knoxville to Medford

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Medford departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Medford

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Medford, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Medford, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$459
American Airlines
Tue 4/21Sat 4/25
TYS - MFR • 2 stops
Cheapest one-way
$393
United Airlines
Mon 8/3
TYS - MFR • 1 stop
Top airlines
Cheapest • from $459 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Medford. You'll need at least 1 connection.
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Medford (TYS-MFR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Medford that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Medford

Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
6:00 am - 4:31 pm
TYS
-
MFR
13h 31m
2 stops
American Airlines Logo
5:20 am - 6:04 pm
MFR
-
TYS
9h 44m
2 stops
$459American Airlines
Fri, Apr 24 - Tue, Apr 28
United Airlines Logo
4:30 pm - 9:37 pm
TYS
-
MFR
8h 07m
1 stop
United Airlines Logo
12:50 pm - 10:29 pm
MFR
-
TYS
6h 39m
1 stop
$469United Airlines
Tue, Apr 21 - Sat, Apr 25
United Airlines Logo
9:00 am - 5:50 pm
TYS
-
MFR
11h 50m
2 stops
United Airlines Logo
12:50 pm - 10:29 pm
MFR
-
TYS
6h 39m
1 stop
$474United Airlines
Fri, Apr 24 - Tue, Apr 28
American Airlines Logo
1:20 pm - 11:04 pm
TYS
-
MFR
12h 44m
2 stops
American Airlines Logo
5:20 am - 6:04 pm
MFR
-
TYS
9h 44m
2 stops
$479American Airlines
Fri, Aug 28 - Sat, Sep 5
Alaska Airlines Logo
1:40 pm - 11:59 pm
TYS
-
MFR
13h 19m
2 stops
Alaska Airlines Logo
6:58 pm - 11:16 am
MFR
-
TYS
13h 18m
2 stops
$483Alaska Airlines
Fri, Aug 28 - Sat, Sep 5
United Airlines Logo
4:56 pm - 9:16 pm
TYS
-
MFR
7h 20m
1 stop
United Airlines Logo
6:26 pm - 10:36 am
MFR
-
TYS
13h 10m
2 stops
$488United Airlines
Fri, Aug 28 - Sat, Sep 5
United Airlines Logo
4:56 pm - 9:16 pm
TYS
-
MFR
7h 20m
1 stop
United Airlines Logo
1:08 pm - 10:38 pm
MFR
-
TYS
6h 30m
1 stop
$493United Airlines
Fri, Aug 28 - Sat, Sep 5
United Airlines Logo
4:56 pm - 9:16 pm
TYS
-
MFR
7h 20m
1 stop
United Airlines Logo
6:26 pm - 10:36 am
MFR
-
TYS
13h 10m
2 stops
$498United Airlines
Fri, May 1 - Fri, May 8
United Airlines Logo
4:20 pm - 9:31 pm
TYS
-
MFR
8h 11m
1 stop
United Airlines Logo
12:52 pm - 10:23 pm
MFR
-
TYS
6h 31m
1 stop
$499United Airlines
Wed, Aug 12 - Thu, Aug 20
United Airlines Logo
4:56 pm - 9:16 pm
TYS
-
MFR
7h 20m
1 stop
United Airlines Logo
1:08 pm - 10:38 pm
MFR
-
TYS
6h 30m
1 stop
$503United Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Medford flights

Get data-powered insights and trends into flights from Knoxville to Medford to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Medford?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Medford were found on American Airlines ($459) and United Airlines ($469).

Good to know

Cheapest flight$393
Flight from Knoxville to Medford

When to book flights from Knoxville to Medford

Are your dates flexible? Find out the best times to travel from Knoxville to Medford based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Medford

  • What is the cheapest flight from Knoxville to Medford?

    In the last 3 days, the lowest price for a flight from Knoxville to Medford was $393 for a one-way ticket and $459 for a round-trip.

  • Do I need a passport to fly between Knoxville and Medford?

    No

  • Which aircraft models fly most regularly from Knoxville to Medford?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Medford?

    Star Alliance is the only airline alliance operating flights between Knoxville and Medford.

  • How does KAYAK find such low prices on flights from Knoxville to Medford?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Medford.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Medford?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Medford from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Medford?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Medford with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MFR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Medford?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Medford from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Medford

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Medford. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Medford? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9562 reviews
7.7Boarding
7.1Entertainment
6.6Food
7.3Comfort
8.1Crew
Airline reviews

Very comfortable flight, snacks and drinks were good, good communication from crew. Could have used a little more information on timing of boarding for group 5

10.0 ExcellentJim, Apr 2026
BWI - ORD
Read more United Airlines reviews

Very comfortable flight, snacks and drinks were good, good communication from crew. Could have used a little more information on timing of boarding for group 5

Great flight. Got to watch a movie. Smooth flight and early arrival at ORD.

This was the first flight in the morning. We boarded fine. The cabin door was closed and we were ready to go. We were notified by the Captain that ATC issued and ground stop for 40 minutes. So, without even pushing back from the gate, we were already 40 minutes late. We actually were released to push-back and taxi at 30 minutes. But, some passengers had tight connections and were not going to make their connections. Some passengers asked about the delay and the effect on the connections and were told by the cabin attendant that all flights will be delayed and so they should be OK. However, that was not true. My connecting flight was on time and I arrived at IAH with 21 minutes to make my connection. I did and I'm happy about that, but the flight crew should not have given assurances to the passengers who might have missed their connections.

Poor communication, flight was delayed for preventable reasons. I missed my connection.

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

After arriving in Chicago, we were taxiing for 1.5 hours with infrequent and untruthful updates about the amount of time it would take to arrive at the gate. Minimally, the team could have provided timing expectations that were more truthful, especially one their original expectations were not met.

Flights were on time actually early service was good and crew cheerful

Every staff member was professional, friendly and courteous. The pizza twist was ok. It was warm but too much dough.

I had a terrible experience. My flight got delayed from Atlanta to Chicago on Monday April 6, 2026, and that led to me missing my next flight to Brussels. United Airlines didn’t provide me with any accommodation for shelter. I had to sleep at the airport in Chicago. The next flight I was put on didn’t leave until the evening hours of Tuesday 4/7/2026.

Boarding was again a "free for all". We were boarding group 4, and almost the entire plane was able to board before us. It's a shame that someone who follows the rules, gets the short end of the stick. Not fair.

Everything you need to know for your flight from Knoxville to Medford

Information on your arrival and departure airports