MFR - TYS

$379 Find Cheap Flights from Medford to Knoxville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to Knoxville departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$379
Delta
Fri 12/4Fri 12/11
MFR - TYS • 2 stops
Top airlines
Delta
Cheapest • from $379 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Medford and Knoxville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 100% price drop
January
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medford to Knoxville (MFR-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to Knoxville

Fri, Dec 4 - Fri, Dec 11
Delta Logo
6:05 am - 9:34 pm
MFR
-
TYS
12h 29m
2 stops
Delta Logo
5:30 am - 12:36 pm
TYS
-
MFR
10h 06m
2 stops
$379Delta
Tue, Jul 21 - Sat, Jul 25
United Airlines Logo
6:35 pm - 10:42 am
MFR
-
TYS
13h 07m
2 stops
United Airlines Logo
4:56 pm - 9:09 pm
TYS
-
MFR
7h 13m
1 stop
$401United Airlines
Tue, Jul 21 - Tue, Jul 28
United Airlines Logo
6:35 pm - 10:42 am
MFR
-
TYS
13h 07m
2 stops
United Airlines Logo
4:56 pm - 9:16 pm
TYS
-
MFR
7h 20m
1 stop
$441United Airlines
Sat, Dec 5 - Wed, Dec 9
United Airlines Logo
5:10 am - 2:36 pm
MFR
-
TYS
6h 26m
1 stop
United Airlines Logo
8:45 am - 1:09 pm
TYS
-
MFR
7h 24m
1 stop
$513United Airlines
Sat, Dec 5 - Wed, Dec 9
United Airlines Logo
6:34 pm - 9:59 am
MFR
-
TYS
12h 25m
2 stops
United Airlines Logo
4:25 pm - 9:10 pm
TYS
-
MFR
7h 45m
1 stop
$518United Airlines
Fri, Dec 4 - Fri, Dec 11
United Airlines Logo
12:45 pm - 10:20 pm
MFR
-
TYS
6h 35m
1 stop
United Airlines Logo
4:25 pm - 9:10 pm
TYS
-
MFR
7h 45m
1 stop
$519United Airlines
Sat, Dec 5 - Wed, Dec 9
United Airlines Logo
6:34 pm - 10:00 am
MFR
-
TYS
12h 26m
2 stops
United Airlines Logo
7:00 am - 5:50 pm
TYS
-
MFR
13h 50m
2 stops
$523United Airlines
Mon, Sep 14 - Sat, Sep 19
United Airlines Logo
6:28 pm - 9:57 am
MFR
-
TYS
12h 29m
2 stops
United Airlines Logo
4:50 pm - 9:08 pm
TYS
-
MFR
7h 18m
1 stop
$524United Airlines
Mon, Sep 14 - Sat, Sep 19
United Airlines Logo
6:28 pm - 9:57 am
MFR
-
TYS
12h 29m
2 stops
United Airlines Logo
6:00 am - 6:13 pm
TYS
-
MFR
15h 13m
2 stops
$529United Airlines
Sat, Dec 5 - Wed, Dec 9
United Airlines Logo
6:34 pm - 10:00 am
MFR
-
TYS
12h 26m
2 stops
United Airlines Logo
7:00 am - 5:50 pm
TYS
-
MFR
13h 50m
2 stops
$561United Airlines
Booking Insights

KAYAK's insights & trends for Medford to Knoxville flights

Get data-powered insights and trends into flights from Medford to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Medford to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medford to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medford to Knoxville is March, where tickets cost $0 (return) on average. On the other hand, the most expensive months are May and January, where the average cost of round-trip tickets is $784 and $721 respectively.

Find deals

Good to know

Low seasonNovember
Cheapest flight$379
Best time to beat the crowds with an average 28% drop in price.
Most popular time to fly with an average 26% increase in price.
Flight from Medford to Knoxville

When to book flights from Medford to Knoxville

Are your dates flexible? Find out the best times to travel from Medford to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Medford to Knoxville

  • What is the cheapest flight from Medford to Knoxville?

    In the last 5 days, the lowest price for a flight from Medford to Knoxville was $379 for a round-trip ticket.

  • Do I need a passport to fly between Medford and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Medford to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medford to Knoxville?

    Star Alliance is the only airline alliance operating flights between Medford and Knoxville.

  • How does KAYAK find such low prices on flights from Medford to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Medford is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Medford with another airline. Booking your flights between Medford and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Medford up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Medford to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Medford to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9909 reviews
7.3Comfort
8.1Crew
7.7Boarding
6.6Food
7.1Entertainment
Airline reviews

They delayed the flight 3 hours because it wasn't full they moved us to 5 different gates probably the worst airline ever not even spirit is this bad.

2.0 Mediocresilvester, Jun 2026
IAH - BNA
Read more United Airlines reviews

They delayed the flight 3 hours because it wasn't full they moved us to 5 different gates probably the worst airline ever not even spirit is this bad.

Poor communication, flight was delayed for preventable reasons. I missed my connection.

We had excellent customer service despite the chaos at George Bush airport in Houston!

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

Once we got in the air the pilot made up some of the time of the delay. So that was really nice.

We boarded but then sat there waiting on some missed connection people to get on so we sat for about 15 minutes for that. Then we sat again because the passenger manifest was wrong and they had to figure it out before we could leave. That took about another 20 minutes or so. The crew was working hard to figure it out so it’s not their fault. It ended up being a system glitch where someone was upgraded to first class while another person was also in the same seat and it just created a mess that took a little while to figure out. They literally went to every person on the plane asking their names to see who was sitting in the wrong seat. I also hate the entertainment that must be watched on your phone or tablet. Just give us setback screens. It’s so much better. Almost every Delta flight has this now and it is so nice to have them. The crew did a great job. I have no complaints from them. They were very hard working, even with the mishap and a disgruntled passenger.

Had a short delay once we boarded the aircraft in Chicago, but it was fixed in no time flat then we were on our way. The pilot was able to make up the time lost and we landed 5 minute later then schedualed . Great service

For some strange reason I was put in zone 5 for boarding even though I had paid premium price for a premium seat right behind business class. This must have been a flaw because everyone else around me in the same zone (row) had been placed in zone 3.

Would had been nice to see a movie without having to pay to watch

Everything you need to know for your flight from Medford to Knoxville

Information on your arrival and departure airports

Medford (MFR)
Knoxville (TYS)