TYS - MSO

$296 Find Cheap Flights from Knoxville to Missoula - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Missoula departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Missoula

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Missoula, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Missoula, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$483
American Airlines
Wed 8/12Thu 8/13
TYS - MSO • 1 stop
Cheapest one-way
$296
Multiple Airlines
Mon 7/13
TYS - MSO • 3 stops
Top airlines
American Airlines
Cheapest • from $483 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Missoula. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Dallas (DFW)
Cheapest • Avg $589 (round-trip)
Denver (DEN)
Shortest trip • 6h 53m (one-way)
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Missoula!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Missoula (TYS-MSO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Missoula that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Missoula

Wed, Aug 12 - Thu, Aug 13
American Airlines Logo
6:03 am - 12:35 pm
TYS
-
MSO
8h 32m
1 stop
American Airlines Logo
1:25 pm - 11:18 pm
MSO
-
TYS
7h 53m
1 stop
$483American Airlines
Wed, Aug 12 - Thu, Aug 13
American Airlines Logo
5:15 am - 12:35 pm
TYS
-
MSO
9h 20m
2 stops
American Airlines Logo
1:25 pm - 11:18 pm
MSO
-
TYS
7h 53m
1 stop
$488American Airlines
Tue, Aug 4 - Fri, Aug 7
United Airlines Logo
6:00 am - 11:32 am
TYS
-
MSO
7h 32m
1 stop
United Airlines Logo
12:34 pm - 8:44 pm
MSO
-
TYS
6h 10m
1 stop
$525United Airlines
Wed, Aug 12 - Thu, Aug 13
American Airlines Logo
5:15 am - 12:35 pm
TYS
-
MSO
9h 20m
2 stops
American Airlines Logo
5:52 pm - 9:43 am
MSO
-
TYS
13h 51m
2 stops
$578American Airlines
Tue, Aug 4 - Fri, Aug 7
American Airlines Logo
5:37 am - 1:17 pm
TYS
-
MSO
9h 40m
1 stop
American Airlines Logo
5:52 pm - 11:10 am
MSO
-
TYS
15h 18m
2 stops
$594American Airlines
Tue, Aug 4 - Fri, Aug 7
American Airlines Logo
5:00 am - 1:17 pm
TYS
-
MSO
10h 17m
2 stops
American Airlines Logo
5:52 pm - 11:10 am
MSO
-
TYS
15h 18m
2 stops
$635American Airlines
Sat, Jul 11 - Tue, Jul 14
United Airlines Logo
4:56 pm - 9:40 pm
TYS
-
MSO
6h 44m
1 stop
United Airlines Logo
6:05 am - 3:53 pm
MSO
-
TYS
7h 48m
1 stop
$717United Airlines
Wed, Aug 12 - Sun, Aug 16
American Airlines Logo
6:03 am - 12:35 pm
TYS
-
MSO
8h 32m
1 stop
American Airlines Logo
1:25 pm - 11:18 pm
MSO
-
TYS
7h 53m
1 stop
$719American Airlines
Fri, Sep 4 - Fri, Sep 11
United Airlines Logo
4:50 pm - 9:31 pm
TYS
-
MSO
6h 41m
1 stop
United Airlines Logo
10:38 am - 10:49 pm
MSO
-
TYS
10h 11m
2 stops
$722United Airlines
Wed, Aug 12 - Sun, Aug 16
American Airlines Logo
5:15 am - 12:35 pm
TYS
-
MSO
9h 20m
2 stops
American Airlines Logo
1:25 pm - 11:18 pm
MSO
-
TYS
7h 53m
1 stop
$724American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Missoula flights

Get data-powered insights and trends into flights from Knoxville to Missoula to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Missoula?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Knoxville to Missoula were found on American Airlines ($483) and United Airlines ($525).

Find deals

Good to know

Cheapest flight$296
Flight from Knoxville to Missoula

When to book flights from Knoxville to Missoula

Are your dates flexible? Find out the best times to travel from Knoxville to Missoula based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Missoula

  • What is the cheapest flight from Knoxville to Missoula?

    In the last 5 days, the lowest price for a flight from Knoxville to Missoula was $296 for a one-way ticket and $483 for a round-trip.

  • Do I need a passport to fly between Knoxville and Missoula?

    No

  • Which aircraft models fly most regularly from Knoxville to Missoula?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Missoula?

    Star Alliance is the only airline alliance operating flights between Knoxville and Missoula.

  • How does KAYAK find such low prices on flights from Knoxville to Missoula?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Missoula.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Missoula?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Missoula from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Missoula?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Missoula with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MSO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Missoula?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Missoula from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Missoula

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Missoula. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Missoula? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9859 reviews
7.1Entertainment
8.1Crew
7.3Comfort
7.7Boarding
6.6Food
Airline reviews

Very easy ! Use the kiosk and bag drop and right to security within 10 min

10.0 ExcellentJoanne, Jun 2026
DEN - ORD
Read more United Airlines reviews

Very easy ! Use the kiosk and bag drop and right to security within 10 min

Checking bag at terminal was horrible. No agents to check us in and only 1 kiosk working. Boarding went ok. Crew onboard was very scattered rained. Missed our row while serving and then didn’t see them hardly again.

Crew was amazing, takeoff wonderful. The bathroom was disgusting from before takeoff the odor made the flight uncomfortable as you could smell the bathroom from the center of the plane where we were sitting. Smelled like raw sewage. My daughter was throwing up as we landed due to the smell and horrible turbulence as we approached Newark.

Airline tickets are not cheap. You expect reliable competent service. Thanks to canceled flights and botched transfers we arrived at our destination two days late. This is not acceptable

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

The entertainment is a bit limited, it would be better if they added some games to play besides the movies and tv shows. But the seats are comfortable and the crew is polite

This planes staff was top tier. Everything went great and had a great flight home.

Food was great. Staff was phenomenal. Seats were a bit hard and could use a lot more entertainment options as far as movies to choose from. WiFi was good. Overall great trip.

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

Everything you need to know for your flight from Knoxville to Missoula

Information on your arrival and departure airports

Knoxville (TYS)
Missoula (MSO)