TYS - MSO

$233 Find Cheap Flights from Knoxville to Missoula - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Missoula departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

Save 20% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$359
American Airlines
Thu 12/10Mon 12/14
TYS - MSO • 1 stop
Cheapest one-way
$233
Delta
Tue 9/15
TYS - MSO • 1 stop
Top airlines
Cheapest • from $359 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Missoula. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $637 (round-trip)
Shortest trip • 6h 53m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Missoula!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Missoula (TYS-MSO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Missoula that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Missoula

Thu, Dec 10 - Mon, Dec 14
American Airlines Logo
7:30 am - 12:35 pm
TYS
-
MSO
7h 05m
1 stop
American Airlines Logo
7:00 am - 3:32 pm
MSO
-
TYS
6h 32m
1 stop
$359American Airlines
Fri, Aug 28 - Fri, Sep 4
American Airlines Logo
6:03 am - 12:35 pm
TYS
-
MSO
8h 32m
1 stop
American Airlines Logo
1:25 pm - 11:18 pm
MSO
-
TYS
7h 53m
1 stop
$359American Airlines
Sat, Aug 29 - Sat, Sep 5
American Airlines Logo
7:19 am - 12:35 pm
TYS
-
MSO
7h 16m
1 stop
American Airlines Logo
1:25 pm - 11:18 pm
MSO
-
TYS
7h 53m
1 stop
$359American Airlines
Sat, Aug 29 - Sat, Sep 5
United Airlines Logo
1:00 pm - 9:31 pm
TYS
-
MSO
10h 31m
2 stops
United Airlines Logo
2:40 pm - 10:29 pm
MSO
-
TYS
5h 49m
1 stop
$364United Airlines
Sat, Sep 12 - Sat, Sep 19
United Airlines Logo
4:50 pm - 9:36 pm
TYS
-
MSO
6h 46m
1 stop
United Airlines Logo
7:00 am - 10:49 pm
MSO
-
TYS
13h 49m
2 stops
$384United Airlines
Fri, Aug 28 - Fri, Sep 4
Delta Logo
5:22 pm - 12:18 am
TYS
-
MSO
8h 56m
2 stops
Delta Logo
6:00 am - 4:41 pm
MSO
-
TYS
8h 41m
1 stop
$384Delta
Thu, Dec 10 - Mon, Dec 14
Delta Logo
6:00 am - 5:42 pm
TYS
-
MSO
13h 42m
2 stops
Delta Logo
8:30 am - 6:26 pm
MSO
-
TYS
7h 56m
2 stops
$389Delta
Sat, Aug 29 - Sat, Sep 5
United Airlines Logo
5:45 am - 1:34 pm
TYS
-
MSO
9h 49m
2 stops
United Airlines Logo
6:15 am - 6:17 pm
MSO
-
TYS
10h 02m
2 stops
$435United Airlines
Thu, Sep 10 - Sun, Sep 13
Multiple Airlines Logo
7:00 am - 8:59 pm
TYS
-
MSO
15h 59m
2 stops
Multiple Airlines Logo
9:49 pm - 3:28 pm
MSO
-
TYS
15h 39m
1 stop
$437Multiple Airlines
Thu, Dec 10 - Mon, Dec 14
American Airlines Logo
7:38 am - 8:33 pm
TYS
-
MSO
14h 55m
2 stops
American Airlines Logo
7:00 am - 5:29 pm
MSO
-
TYS
8h 29m
1 stop
$553American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Missoula flights

Get data-powered insights and trends into flights from Knoxville to Missoula to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Missoula?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Knoxville to Missoula were found on American Airlines ($359) and Delta ($384).

Good to know

Cheapest flight

$233
Flight from Knoxville to Missoula

When to book flights from Knoxville to Missoula

Are your dates flexible? Find out the best times to travel from Knoxville to Missoula based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Missoula

  • What is the cheapest flight from Knoxville to Missoula?

    In the last 5 days, the lowest price for a flight from Knoxville to Missoula was $233 for a one-way ticket and $359 for a round-trip.

  • Do I need a passport to fly between Knoxville and Missoula?

    No

  • Which aircraft models fly most regularly from Knoxville to Missoula?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Missoula?

    Star Alliance is the only airline alliance operating flights between Knoxville and Missoula.

  • How does KAYAK find such low prices on flights from Knoxville to Missoula?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Missoula.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Missoula?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Missoula from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Missoula?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Missoula with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MSO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Missoula?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Missoula from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Missoula

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Missoula. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Missoula? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 10062 reviews
6.7Food
8.1Crew
7.7Boarding
7.1Entertainment
7.3Comfort
Airline reviews

The head rest is too big and cannot be placed differently/removed. Causes one head to tilt forward and increase back pain

8.0 ExcellentKatiuscia, Jul 2026
TYS - ORD
Read more United Airlines reviews

The head rest is too big and cannot be placed differently/removed. Causes one head to tilt forward and increase back pain

Our flight to Rome, Italy was cancelled the day of and we were never informed. We only found out because I was trying to get into my husbands account and called to get his account number. Had to pay more for worse seating on another airline.

I wish there were outlets to charge my iPhone. The crew was great; we had a female pilot who was great with explaining what was happening and delays,

The staff was hospitable and professional. The seat had a bit of wear. The winner shade was stuck 1/4 open. I received the best of both worlds. The morning sun was able to come in and blind the screen i was trying to use while at the same time it was too low to look out and enjoy the view. Rather embarrassing for a 1st class ticket.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Even though we were delayed, we were able to make our connection

Another delayed flight. When the delays exceed the duration of the flight, it’s a problem.

Trip was great. A wild landing in Ottawa with the wind and rain, but the pilot did a great job. Always love flying United.👍

The internet service I paid for didn’t work at all and the flight crew was not very friendly.

Please please take consideration when setting cabin temperature. The vents were not functional and it was over 70 degrees in the cabin during the winter months when most people are used to much cooler indoor temperatures. I was down to my white t-shirt and the sweat pants I wore from Auckland to San Francisco and was sweating profusely and there was NO VENT!

It was a 3 hour flight from Dallas to Missoula. The aircraft did not have power plugs, internet or in-flight entertainment. When boarding, one flight attendant was "somewhere in the airport" so delayed the boarding process (not coming from another flight) although we did take off on time and landed early. In flight there was little to no service - we got the standard beverage but no real connection with the crew which feels unusual for a 3 hour flight. A passenger needed help stowing her bag and got no assistance, and actually some passive aggressive comments from the flight attendants about "she needs to remove the extender" and "she'll have to find a place for it". I have seen others be helpful and put a bag in the closet, or support assistance as the boarding door was already closed. Just not a great experience considering the cost of my round trip ticket {$1000}.

Not one thing to like. Three flights all with “mechanical” delays. Never got to where I was going and spent additional $500 for a hotel room. American Airlines is the worst in the industry!

Not to have gotten delayed by 2+ hours for the fourth straight American flight. They're the worst.

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

I didn’t like anything, being platinum pro get you absolutely nowhere and does not increase the customer service treatment whatsoever anymore. My flight was canceled and they put me on a flight eight hours later that would’ve got me back in the middle of the night. They could’ve easily move me up to an hour Prior on an earlier flight. My second flight was unreasonable to take, the third flight was also canceled due to mechanical issues like the first flight. I don’t know what’s going on with American, but they are falling apart, after seven flight changes I finally got home, Unreasonable.

You were more on time than United. I'm so over united delays.

This was a horrible American Airlines experience, and it discourages me from flying with them again. It may have stemmed from a mechanical delay, but it appeared that the team was unprepared to respond to the delay. After boarding, we waited an hour before finally taking off. After landing at our destination, we waited an additional hour on the tarmac waiting for a gate (at 8:00pm) to be assigned and cleared. The flight crew did their best, but they were clearly tired and also ready to be done for the day. Because of the delay, I missed a connecting flight. It was a very poor experience.

Fantastic! If it had not been for a check-in agent in Knoxville I may have not gotten my passes on British Airways. I couldn’t check-in online because British Airways had messed us the info on my tickets to London & Inverness. AA’s was great! British Airways was a continuous series of delays and frustrations.

Wheelchair was waiting for me,changed to a better seat which was great as it's hard for me to walk

Everything you need to know for your flight from Knoxville to Missoula

Information on your arrival and departure airports