TYS - MSO

$379 Find Cheap Flights from Knoxville to Missoula - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$379
Typical prices: $427-$758
American Airlines
Sun 11/18Thu 11/22
TYS - MSO • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Missoula. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 46% price drop
July
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Chicago O'Hare Intl (ORD)
Cheapest • Avg $523 (round-trip)
Denver Intl (DEN)
Shortest trip • 6h 34m (one-way)
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Insights
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Flight Deals

Cheap Flights from Knoxville to Missoula (TYS-MSO)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Missoula

Wed, Nov 18 - Sun, Nov 22
American Airlines Logo
2:55 pm - 8:15 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
7h 20m1 stop Dallas/Fort Worth
American Airlines Logo
1:18 pm - 11:47 pmMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
8h 29m1 stop Chicago O'Hare Intl
$379American Airlines
Sat, Oct 24 - Sat, Nov 7
United Airlines Logo
9:00 am - 1:32 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
6h 32m1 stop Denver Intl
United Airlines Logo
2:37 pm - 10:32 pmMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
5h 55m1 stop Denver Intl
$379United Airlines
Sat, Oct 24 - Tue, Nov 10
United Airlines Logo
9:00 am - 1:32 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
6h 32m1 stop Denver Intl
United Airlines Logo
2:37 pm - 10:32 pmMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
5h 55m1 stop Denver Intl
$379United Airlines
Sat, Oct 24 - Sat, Nov 7
United Airlines Logo
6:00 am - 4:20 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
12h 20m2 stops Chicago O'Hare Intl Denver Intl
United Airlines Logo
6:15 am - 4:04 pmMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
7h 49m1 stop Denver Intl
$384United Airlines
Wed, Nov 18 - Sun, Nov 22
American Airlines Logo
2:55 pm - 8:15 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
7h 20m1 stop Dallas/Fort Worth
American Airlines Logo
1:18 pm - 11:59 pmMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
8h 41m2 stops Chicago O'Hare Intl Charlotte Douglas
$384American Airlines
Sat, Oct 24 - Thu, Nov 12
Delta Logo
5:40 am - 12:34 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
8h 54m2 stops Atlanta Hartsfield-Jackson Salt Lake City
Delta Logo
1:19 pm - 11:59 pmMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
8h 40m2 stops Salt Lake City Atlanta Hartsfield-Jackson
$389Delta
Sat, Oct 24 - Tue, Nov 10
Delta Logo
5:40 am - 12:34 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
8h 54m2 stops Atlanta Hartsfield-Jackson Salt Lake City
Delta Logo
5:20 am - 5:49 pmMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
10h 29m2 stops Salt Lake City Detroit Metropolitan Wayne County
$389Delta
Sat, Oct 24 - Sat, Nov 7
American Airlines Logo
7:30 am - 12:35 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
7h 05m1 stop Chicago O'Hare Intl
American Airlines Logo
1:06 pm - 10:51 pmMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
7h 45m1 stop Chicago O'Hare Intl
$459American Airlines
Sat, Oct 24 - Wed, Nov 11
Delta Logo
5:40 am - 12:34 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
8h 54m2 stops Atlanta Hartsfield-Jackson Salt Lake City
Delta Logo
8:30 am - 5:49 pmMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
7h 19m2 stops Minneapolis St Paul Detroit Metropolitan Wayne County
$468Delta
Mon, Sep 28 - Tue, Oct 13
American Airlines Logo
8:15 pm - 12:11 pmTYS  Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field
17h 56m2 stops Chicago O'Hare Intl Dallas/Fort Worth
American Airlines Logo
1:48 pm - 10:23 amMSO  Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson
18h 35m2 stops Chicago O'Hare Intl Charlotte Douglas
$1,020American Airlines
Booking Insights

Price, demand and travel trends for Knoxville to Missoula flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Knoxville to Missoula with more confidence.

How much is a round-trip flight from Knoxville to Missoula?

Round-trip flights from Knoxville to Missoula start at $379. Prices are below average for this route right now, with typical round-trip fares ranging from $427 to $758. The lowest price found in the past 5 days was $379 on American Airlines.

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Key details for Knoxville to Missoula flights

Low season

January
Best time to beat the crowds with an average 46% drop in price.
Most popular time to fly with an average 52% increase in price.

When to book flights from Knoxville to Missoula

Are your dates flexible? Find out the best times to travel from Knoxville to Missoula based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Missoula flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Knoxville to Missoula?

    Flights from Knoxville to Missoula usually depart from Knoxville McGhee Tyson (TYS) and arrive at Missoula Johnson-Bell Field (MSO).

  • What cabin classes can I book on flights from Knoxville to Missoula?

    Only Economy Class is available on flights from Knoxville to Missoula.

  • Which airports do connecting flights from Knoxville to Missoula pass through?

    One-stop flights from Knoxville to Missoula most commonly connect through:

    • Denver Intl (DEN) - 50% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 25% of one-stop connections
    • Dallas/Fort Worth (DFW) - 21% of one-stop connections
    • Minneapolis St Paul (MSP) - 4% of one-stop connections

    Denver Intl (DEN) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Knoxville to Missoula?

    Yes. Being flexible with your travel dates can save you up to 51% on the Knoxville to Missoula route. Tuesday is the cheapest departure day at $398 round-trip on average, while Saturday is the most expensive at $810, a difference of $412. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How long is a flight from Knoxville to Missoula?

    A nonstop flight from Knoxville to Missoula takes 0h 00m, covering 1,724 miles.

  • Do I need a passport to fly from Knoxville to Missoula?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • How much time can I save by choosing a different layover airport from Knoxville to Missoula?

    Flying via Denver Intl (DEN) gives the shortest average 1-stop total travel time at 6h 34m, compared with 6h 54m via Chicago O'Hare Intl (ORD) and 7h 55m via Dallas/Fort Worth (DFW).

  • What is the time difference between Knoxville and Missoula?

    Missoula is 2 hours behind Knoxville (Mountain Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Missoula Johnson-Bell Field Airport (MSO)?

    Missoula Johnson-Bell Field Airport (MSO) hosts 5 major car rental companies, with daily rates starting from around $22 for economy cars. Top options include:
    • Dollar
    • Budget
    • Hertz
    • Thrifty
    • Avis

  • How much should I expect to pay for a Knoxville to Missoula flight?

    Round-trip flights from Knoxville to Missoula range from $427 to $758, with an average of $534 over the past 12 months. Anything below $427 counts as a good deal.

Your guide to booking Knoxville to Missoula flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Tuesday departure instead of Saturday. On this route, Tuesday flights average $398 - about $412 less than Saturday (51% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Knoxville to Missoula trip for January. Fares historically average $288 round-trip in that month - typically $522 less than the most expensive month, which is July (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Missoula Johnson-Bell Field Airport.
    - Fairfield Inn & Suites by Marriott Missoula
    - StoneCreek Lodge

More options for your flight from Knoxville to Missoula

Complete your trip to Missoula with a hotel stay or car rental

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Hotels in Missoula
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