Which airports can I use when flying from Missoula to Knoxville?

Flights from Missoula to Knoxville usually depart from Missoula Johnson-Bell Field (MSO) and arrive at Knoxville McGhee Tyson (TYS).

What cabin classes can I book on flights from Missoula to Knoxville?

Only Economy Class is available on flights from Missoula to Knoxville.

Which airports do connecting flights from Missoula to Knoxville pass through?

Connecting flights from Missoula to Knoxville most commonly pass through: • Denver Intl (DEN) - 78% of one-stop connections • Chicago O'Hare Intl (ORD) - 22% of one-stop connections

Can I save money by using flexible dates for flights from Missoula to Knoxville?

Yes. Flexible dates can save you up to 33% on flights from Missoula to Knoxville. Thursday is the cheapest departure day at $525 round-trip on average, while Sunday is the most expensive at $773, a difference of $248. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Missoula to Knoxville?

A nonstop flight from Missoula to Knoxville takes 00m, covering 1,724 miles.

Do I need a passport to fly from Missoula to Knoxville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

How much time can I save by choosing a different layover airport from Missoula to Knoxville?

Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 6h 56m, compared with 6h 59m via Denver Intl (DEN).

What is the time difference between Missoula and Knoxville?

Knoxville is 2 hours ahead of Missoula (Eastern Time vs Mountain Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $80 for economy cars. Top options include: • Budget • Alamo • Enterprise Rent-A-Car • Thrifty • Avis

How much should I expect to pay for a Missoula to Knoxville flight?

Round-trip flights from Missoula to Knoxville range from $503 to $713, with an average of $584 over the past 12 months. Anything below $503 counts as a good deal.

How much is a round-trip flight from Missoula to Knoxville?

Round-trip flights from Missoula to Knoxville typically range from $503 to $713. The lowest price found in the past 5 days was $379, on United Airlines.

Which airline is the cheapest to fly from Missoula to Knoxville?

United Airlines ($379) and Delta ($479) are the cheapest airlines to fly round-trip from Missoula to Knoxville according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Missoula to Knoxville?

Denver Intl (DEN) is the most popular layover for the Missoula to Knoxville route. 78% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via DEN.

What is the cheapest layover airport when flying from Missoula to Knoxville?

Flights via Chicago O'Hare Intl (ORD) offer the most affordable fares, with an average round-trip price of $471. Based on KAYAK data over the past 3 months.

When flying from Missoula to Knoxville which airport offers the shortest layover?

Denver Intl (DEN) had the shortest average connection time for Missoula to Knoxville layovers at 4h 09m over the past 3 months.

$379 CHEAP FLIGHTS from Missoula to Knoxville (MSO - TYS)

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Cheapest round-trip

$379

Typical prices: $503-$713

United Airlines

Wed 12/5Fri 12/14

MSO - TYS • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Missoula and Knoxville. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

July

Cheapest • 35% price drop

September

Most popular

Good to know

Top layover airports

Chicago O'Hare Intl (ORD)

Cheapest • Avg $471 (round-trip)

Denver Intl (DEN)

Shortest trip • 6h 59m (one-way)

Insights

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We hope you love your trip to Knoxville!

Flight Deals

Cheap Flights from Missoula to Knoxville (MSO-TYS)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Recent round-trip flight deals from Missoula to Knoxville

Sat, Dec 5 - Mon, Dec 14

2:41 pm - 10:50 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

6h 09m1 stop Denver Intl

4:43 pm - 9:47 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

7h 04m1 stop Denver Intl

$379United Airlines

Sat, Dec 5 - Mon, Dec 14

6:15 am - 8:37 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

12h 22m2 stops Denver Intl Newark

4:43 pm - 9:47 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

7h 04m1 stop Denver Intl

$384United Airlines

Sat, Dec 5 - Sun, Dec 13

6:15 am - 8:47 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

12h 32m2 stops Denver Intl Chicago O'Hare Intl

6:00 am - 1:32 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

9h 32m2 stops Chicago O'Hare Intl Denver Intl

$440United Airlines

Sun, Dec 6 - Sun, Dec 13

6:15 am - 8:47 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

12h 32m2 stops Denver Intl Chicago O'Hare Intl

6:00 am - 1:32 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

9h 32m2 stops Chicago O'Hare Intl Denver Intl

$440United Airlines

Thu, Nov 12 - Mon, Nov 16

2:37 pm - 10:32 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

5h 55m1 stop Denver Intl

5:05 pm - 9:47 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

6h 42m1 stop Denver Intl

$461United Airlines

Fri, Dec 4 - Sat, Dec 12

5:25 am - 7:34 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

12h 09m2 stops Salt Lake City Atlanta Hartsfield-Jackson

7:10 am - 5:45 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

12h 35m2 stops Detroit Metropolitan Wayne County Salt Lake City

$479Delta

Sat, Dec 5 - Sat, Dec 12

8:27 am - 6:56 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

8h 29m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

7:10 am - 5:45 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

12h 35m2 stops Detroit Metropolitan Wayne County Salt Lake City

$479Delta

Sat, Jan 30 - Wed, Feb 3

6:10 am - 2:56 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

6h 46m1 stop Denver Intl

4:28 pm - 9:52 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

7h 24m1 stop Denver Intl

$499United Airlines

Sat, Dec 5 - Sat, Dec 12

2:41 pm - 10:50 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

6h 09m1 stop Denver Intl

4:43 pm - 9:47 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

7h 04m1 stop Denver Intl

$499United Airlines

Mon, Dec 7 - Sat, Dec 12

2:41 pm - 10:50 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

6h 09m1 stop Denver Intl

4:43 pm - 9:47 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

7h 04m1 stop Denver Intl

$499United Airlines

Booking Insights

Price, demand and travel trends for Missoula to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Missoula to Knoxville? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Missoula to Knoxville departing in december.

Find deals

Low season	June
High season	September
Cheapest flight	$379

Beat the crowds with an average 70% drop in travelers.

The most popular month to fly with an average 87% increase in travelers.

Round-trip flight from Missoula to Knoxville

When to book flights from Missoula to Knoxville

Are your dates flexible? Find out the best times to travel from Missoula to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Missoula to Knoxville?
Only Economy Class is available on flights from Missoula to Knoxville.
How long is a flight from Missoula to Knoxville?
A nonstop flight from Missoula to Knoxville takes 00m, covering 1,724 miles.
Do I need a passport to fly from Missoula to Knoxville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Missoula to Knoxville flight?
Round-trip flights from Missoula to Knoxville range from $503 to $713, with an average of $584 over the past 12 months. Anything below $503 counts as a good deal.
What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?
Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $80 for economy cars. Top options include:

• Budget
• Alamo
• Enterprise Rent-A-Car
• Thrifty
• Avis
Which airports can I use when flying from Missoula to Knoxville?
Flights from Missoula to Knoxville usually depart from Missoula Johnson-Bell Field (MSO) and arrive at Knoxville McGhee Tyson (TYS).
Which airports do connecting flights from Missoula to Knoxville pass through?
Connecting flights from Missoula to Knoxville most commonly pass through:

• Denver Intl (DEN) - 78% of one-stop connections
• Chicago O'Hare Intl (ORD) - 22% of one-stop connections
Can I save money by using flexible dates for flights from Missoula to Knoxville?
Yes. Flexible dates can save you up to 33% on flights from Missoula to Knoxville. Thursday is the cheapest departure day at $525 round-trip on average, while Sunday is the most expensive at $773, a difference of $248.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Missoula to Knoxville?
Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 6h 56m, compared with 6h 59m via Denver Intl (DEN).
What is the time difference between Missoula and Knoxville?
Knoxville is 2 hours ahead of Missoula (Eastern Time vs Mountain Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Thursday departure and avoid flying on Sunday. On this route, Thursday flights average $525, about $248 less than Sunday fares (32% savings) based on the last 12 months.
If you can choose when to travel, plan your Missoula to Knoxville trip for July. Fares historically average $380 round-trip in that month - typically $441 less than the most expensive month, which is January (based on the last 12 months).

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MSO - TYS

$379 Find Cheap Flights from Missoula to Knoxville - Compare and Save

Everything you should know

Cheap Flights from Missoula to Knoxville (MSO-TYS)

Recent round-trip flight deals from Missoula to Knoxville

Recent one-way flight deals from Missoula to Knoxville

Price, demand and travel trends for Missoula to Knoxville flights

How much is a round-trip flight from Missoula to Knoxville?

Which airline is the cheapest to fly from Missoula to Knoxville?

What’s the most popular layover airport when flying from Missoula to Knoxville?

What is the cheapest layover airport when flying from Missoula to Knoxville?

When flying from Missoula to Knoxville which airport offers the shortest layover?

Key details for Missoula to Knoxville flights

Low season

High season

Cheapest flight

When to book flights from Missoula to Knoxville

Your Missoula to Knoxville flight questions, answered

Your guide to booking Missoula to Knoxville flights

More options for your flight from Missoula to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Missoula to Knoxville

Find direct flights to and from Missoula and Knoxville

Flights from domestic origins to Knoxville

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