Which airports can I use when flying from Missoula to Knoxville?

Flights from Missoula to Knoxville usually depart from Missoula Johnson-Bell Field (MSO) and arrive at Knoxville McGhee Tyson (TYS).

What cabin classes can I book on flights from Missoula to Knoxville?

Two cabin classes are available on flights from Missoula to Knoxville: • Economy Class • First Class

Which airports do connecting flights from Missoula to Knoxville pass through?

Connecting flights from Missoula to Knoxville most commonly pass through: • Denver Intl (DEN) - 77% of one-stop connections • Chicago O'Hare Intl (ORD) - 23% of one-stop connections Together, these airports account for 100% of one-stop bookings on this route.

Can I save money by using flexible dates for flights from Missoula to Knoxville?

Yes. Being flexible with your travel dates can save you up to 46% on the Missoula to Knoxville route. Thursday is the cheapest departure day at $525 round-trip on average, while Tuesday is the most expensive at $965, a difference of $440. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Missoula to Knoxville?

A nonstop flight from Missoula to Knoxville takes 0h 00m, covering 1,724 miles.

Do I need a passport to fly from Missoula to Knoxville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from Missoula to Knoxville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $379 to $3,632. That means the highest observed fare was about 10x higher than the lowest one.

How are flight prices from Missoula to Knoxville looking right now?

One-way fares from Missoula to Knoxville are currently higher than usual. Average one-way flight prices are about $490, which is 68% above the typical average for this route.

How much time can I save by choosing a different layover airport from Missoula to Knoxville?

Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 6h 55m, compared with 6h 58m via Denver Intl (DEN).

What is the time difference between Missoula and Knoxville?

Knoxville is 2 hours ahead of Missoula (Eastern Time vs Mountain Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include: • Budget • Alamo • Thrifty • Enterprise Rent-A-Car • Payless

How much should I expect to pay for a Missoula to Knoxville flight?

Round-trip flights from Missoula to Knoxville range from $480 to $713, with an average of $584 over the past 12 months. Anything below $480 counts as a good deal.

What is the cheapest airline to fly from Missoula to Knoxville?

United Airlines ($379) and American Airlines ($379) are the cheapest airlines to fly round-trip from Missoula to Knoxville according to KAYAK data over the last 5 days.

What is the most popular layover airport when flying from Missoula to Knoxville?

Denver Intl (DEN) is the most popular layover for the Missoula to Knoxville route. 77% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via DEN.

What is the cheapest layover airport when flying from Missoula to Knoxville?

Flights via Chicago O'Hare Intl (ORD) offer the most affordable fares, with an average round-trip price of $440. Based on KAYAK data over the past 3 months.

When flying from Missoula to Knoxville which airport offers the shortest layover?

Denver Intl (DEN) had the shortest average connection time for Missoula to Knoxville layovers at 247 minutes over the past 3 months.

$291 CHEAP FLIGHTS from Missoula to Knoxville (MSO - TYS)

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Cheapest round-trip

$379

Typical prices: $480-$713

United Airlines

Wed 10/17Wed 10/24

MSO - TYS • 1 stop

Cheapest one-way

$291

Typical prices: $266-$407

United Airlines

Wed 10/17

MSO - TYS • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Missoula and Knoxville. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

July

Cheapest • 35% price drop

September

Most popular

Good to know

Top layover airports

Chicago O'Hare Intl (ORD)

Cheapest • Avg $440 (round-trip)

Denver Intl (DEN)

Shortest trip • 6h 58m (one-way)

Insights

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Flight Deals

Cheap Flights from Missoula to Knoxville (MSO-TYS)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Recent round-trip flight deals from Missoula to Knoxville

Fri, Oct 23 - Wed, Oct 28

1:48 pm - 11:59 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

8h 11m1 stop Chicago O'Hare Intl

6:00 am - 1:18 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

9h 18m1 stop Dallas/Fort Worth

$379American Airlines

Fri, Feb 5 - Mon, Feb 8

1:45 pm - 11:50 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

8h 05m1 stop Chicago O'Hare Intl

7:49 am - 12:35 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

6h 46m1 stop Chicago O'Hare Intl

$379American Airlines

Sat, Oct 17 - Sat, Oct 24

2:38 pm - 10:14 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

5h 36m1 stop Denver Intl

9:00 am - 1:32 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

6h 32m1 stop Denver Intl

$379United Airlines

Sat, Oct 17 - Sat, Oct 24

2:38 pm - 10:14 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

5h 36m1 stop Denver Intl

6:00 am - 4:20 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

12h 20m2 stops Chicago O'Hare Intl Denver Intl

$384United Airlines

Fri, Feb 5 - Mon, Feb 8

8:00 am - 6:13 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

8h 13m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

7:55 am - 5:27 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

11h 32m2 stops Minneapolis St Paul Salt Lake City

$389Delta

Thu, Dec 10 - Mon, Dec 14

1:06 pm - 11:47 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

8h 41m1 stop Chicago O'Hare Intl

7:52 am - 12:36 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

6h 44m1 stop Chicago O'Hare Intl

$432American Airlines

Fri, Oct 23 - Wed, Oct 28

2:38 pm - 10:14 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

5h 36m1 stop Denver Intl

7:00 am - 4:26 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

11h 26m2 stops Houston George Bush Intcntl Denver Intl

$445United Airlines

Sat, Jan 30 - Wed, Feb 3

6:15 am - 2:36 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

6h 21m1 stop Denver Intl

4:25 pm - 9:26 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

7h 01m1 stop Denver Intl

$479United Airlines

Thu, Oct 1 - Mon, Oct 5

12:28 pm - 8:49 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

6h 21m1 stop Chicago O'Hare Intl

6:00 am - 11:32 amTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

7h 32m1 stop Chicago O'Hare Intl

$479United Airlines

Sat, Jan 30 - Wed, Feb 3

6:15 am - 5:03 pmMSO Missoula Johnson-Bell Field-TYS Knoxville McGhee Tyson

8h 48m2 stops Denver Intl Chicago O'Hare Intl

4:25 pm - 9:26 pmTYS Knoxville McGhee Tyson-MSO Missoula Johnson-Bell Field

7h 01m1 stop Denver Intl

$484United Airlines

Booking Insights

Price, demand and travel trends for Missoula to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Missoula to Knoxville with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Missoula to Knoxville?

Round-trip flights from Missoula to Knoxville start at $379. Prices are below average for this route right now, with typical round-trip fares ranging from $480 to $713. The lowest price found in the past 5 days was $379 on United Airlines.

Find deals

Low season	June
High season	September
Cheapest flight	$291

Best time to beat the crowds but there is an average 14% increase in price.

Most popular time to fly and prices are also 23% lower on average.

Flight from Missoula to Knoxville

When to book flights from Missoula to Knoxville

Are your dates flexible? Find out the best times to travel from Missoula to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from Missoula to Knoxville?
Flights from Missoula to Knoxville usually depart from Missoula Johnson-Bell Field (MSO) and arrive at Knoxville McGhee Tyson (TYS).
What cabin classes can I book on flights from Missoula to Knoxville?
Two cabin classes are available on flights from Missoula to Knoxville:

• Economy Class
• First Class
Which airports do connecting flights from Missoula to Knoxville pass through?
Connecting flights from Missoula to Knoxville most commonly pass through:

• Denver Intl (DEN) - 77% of one-stop connections
• Chicago O'Hare Intl (ORD) - 23% of one-stop connections
Together, these airports account for 100% of one-stop bookings on this route.
Can I save money by using flexible dates for flights from Missoula to Knoxville?
Yes. Being flexible with your travel dates can save you up to 46% on the Missoula to Knoxville route. Thursday is the cheapest departure day at $525 round-trip on average, while Tuesday is the most expensive at $965, a difference of $440. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How long is a flight from Missoula to Knoxville?
A nonstop flight from Missoula to Knoxville takes 0h 00m, covering 1,724 miles.
Do I need a passport to fly from Missoula to Knoxville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
Have flight prices from Missoula to Knoxville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $379 to $3,632. That means the highest observed fare was about 10x higher than the lowest one.
How are flight prices from Missoula to Knoxville looking right now?
One-way fares from Missoula to Knoxville are currently higher than usual. Average one-way flight prices are about $490, which is 68% above the typical average for this route.
How much time can I save by choosing a different layover airport from Missoula to Knoxville?
Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 6h 55m, compared with 6h 58m via Denver Intl (DEN).
What is the time difference between Missoula and Knoxville?
Knoxville is 2 hours ahead of Missoula (Eastern Time vs Mountain Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?
Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
• Budget
• Alamo
• Thrifty
• Enterprise Rent-A-Car
• Payless
How much should I expect to pay for a Missoula to Knoxville flight?
Round-trip flights from Missoula to Knoxville range from $480 to $713, with an average of $584 over the past 12 months. Anything below $480 counts as a good deal.

If your dates can be flexible, aim for a Thursday departure instead of Tuesday. On this route, Thursday flights average $525 - about $440 less than Tuesday (46% savings) based on the last 12 months.
If you can choose when to travel, plan your Missoula to Knoxville trip for July. Fares historically average $380 round-trip in that month - typically $441 less than the most expensive month, which is January (based on the last 12 months).

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MSO - TYS

$291 Find Cheap Flights from Missoula to Knoxville - Compare and Save

Everything you should know

Cheap Flights from Missoula to Knoxville (MSO-TYS)

Recent round-trip flight deals from Missoula to Knoxville

Recent one-way flight deals from Missoula to Knoxville

Price, demand and travel trends for Missoula to Knoxville flights

How much is a round-trip flight from Missoula to Knoxville?

What is the cheapest airline to fly from Missoula to Knoxville?

What is the most popular layover airport when flying from Missoula to Knoxville?

What is the cheapest layover airport when flying from Missoula to Knoxville?

When flying from Missoula to Knoxville which airport offers the shortest layover?

Key details for Missoula to Knoxville flights

Low season

High season

Cheapest flight

When to book flights from Missoula to Knoxville

Your Missoula to Knoxville flight questions, answered

Your guide to booking Missoula to Knoxville flights

More options for your flight from Missoula to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Missoula to Knoxville

Find direct flights to and from Missoula and Knoxville

Flights from domestic origins to Knoxville

Flights to other popular destinations

Find deals for your return flight