MSO - TYS

$233 Find Cheap Flights from Missoula to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Missoula to Knoxville departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Missoula to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Missoula to Knoxville, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$374
United Airlines
Mon 4/13Sat 4/18
MSO - TYS • 1 stop
Cheapest one-way
$233
United Airlines
Tue 7/14
MSO - TYS • 2 stops
Top airlines
Cheapest • from $374 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Missoula and Knoxville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $428 (round-trip)
Shortest trip • 6h 29m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Missoula to Knoxville (MSO-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Missoula to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Missoula to Knoxville

Mon, Apr 13 - Sat, Apr 18
United Airlines Logo
2:38 pm - 10:29 pm
MSO
-
TYS
5h 51m
1 stop
United Airlines Logo
10:49 am - 9:30 pm
TYS
-
MSO
12h 41m
2 stops
$374United Airlines
Tue, May 19 - Tue, May 26
American Airlines Logo
6:45 am - 3:19 pm
MSO
-
TYS
6h 34m
1 stop
American Airlines Logo
5:36 am - 1:18 pm
TYS
-
MSO
9h 42m
1 stop
$402American Airlines
Tue, May 19 - Tue, May 26
American Airlines Logo
6:45 am - 3:19 pm
MSO
-
TYS
6h 34m
1 stop
American Airlines Logo
5:36 am - 1:18 pm
TYS
-
MSO
9h 42m
1 stop
$417American Airlines
Tue, Mar 31 - Sat, Apr 4
United Airlines Logo
2:38 pm - 10:29 pm
MSO
-
TYS
5h 51m
1 stop
United Airlines Logo
4:30 pm - 9:30 pm
TYS
-
MSO
7h 00m
1 stop
$419United Airlines
Tue, Jun 9 - Tue, Jun 16
American Airlines Logo
2:08 pm - 11:53 pm
MSO
-
TYS
7h 45m
1 stop
American Airlines Logo
7:07 am - 12:49 pm
TYS
-
MSO
7h 42m
1 stop
$422American Airlines
Tue, Mar 31 - Sat, Apr 4
United Airlines Logo
2:38 pm - 10:29 pm
MSO
-
TYS
5h 51m
1 stop
United Airlines Logo
11:40 am - 9:30 pm
TYS
-
MSO
11h 50m
2 stops
$424United Airlines
Mon, Apr 13 - Sat, Apr 18
American Airlines Logo
6:45 am - 6:04 pm
MSO
-
TYS
9h 19m
1 stop
American Airlines Logo
4:09 pm - 9:45 pm
TYS
-
MSO
7h 36m
1 stop
$434American Airlines
Tue, May 19 - Tue, May 26
American Airlines Logo
6:45 am - 3:19 pm
MSO
-
TYS
6h 34m
1 stop
American Airlines Logo
5:36 am - 1:18 pm
TYS
-
MSO
9h 42m
1 stop
$435American Airlines
Tue, May 19 - Tue, May 26
American Airlines Logo
6:45 am - 3:19 pm
MSO
-
TYS
6h 34m
1 stop
American Airlines Logo
5:36 am - 1:18 pm
TYS
-
MSO
9h 42m
1 stop
$441American Airlines
Tue, Jun 9 - Tue, Jun 16
American Airlines Logo
2:08 pm - 11:53 pm
MSO
-
TYS
7h 45m
1 stop
American Airlines Logo
5:36 am - 1:18 pm
TYS
-
MSO
9h 42m
1 stop
$456American Airlines
Booking Insights

KAYAK's insights & trends for Missoula to Knoxville flights

Get data-powered insights and trends into flights from Missoula to Knoxville to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Missoula to Knoxville?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Missoula to Knoxville were found on United Airlines ($374) and American Airlines ($402).

Good to know

Low seasonSeptember
Cheapest flight$233
Best time to beat the crowds with an average 33% drop in price.
Most popular time to fly and prices are also 15% lower on average.
Flight from Missoula to Knoxville

When to book flights from Missoula to Knoxville

Are your dates flexible? Find out the best times to travel from Missoula to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Missoula to Knoxville

  • What is the cheapest flight from Missoula to Knoxville?

    In the last 3 days, the lowest price for a flight from Missoula to Knoxville was $233 for a one-way ticket and $374 for a round-trip.

  • Do I need a passport to fly between Missoula and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Missoula to Knoxville?

    On your way to Knoxville, you’ll fly out from Missoula Johnson-Bell Field. You’ll be landing at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Missoula to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Missoula to Knoxville?

    oneworld, and Star Alliance are the airline alliances operating flights between Missoula and Knoxville, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Missoula to Knoxville, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Missoula to Knoxville are United Airlines and American Airlines. With an average price for the route of $545 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $529 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Missoula to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Missoula to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Missoula to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Missoula is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Missoula to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Missoula with another airline. Booking your flights between Missoula and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Missoula to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Missoula up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Missoula to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Missoula to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Missoula to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9451 reviews
8.1Crew
7.3Comfort
7.7Boarding
6.6Food
7.1Entertainment
Airline reviews

Good quick flight on a small but comfortable plane. I'm 6'3 and had plenty of space.

8.0 ExcellentMatthew, Mar 2026
IAD - CMH
Read more United Airlines reviews

Good quick flight on a small but comfortable plane. I'm 6'3 and had plenty of space.

Experience was great - no complaints. Took off on time, landed early. Got to the gate relatively quickly - took a little bit of extra time to deplane but nothing excessive.

Economy plus was so cramped I could not use my laptop. It was beyond bad.

OK, we were delayed and had to de plane and reboard.

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

Both our flights were delayed. Almost didn’t get in the second flight. Staff was rude to the bone.

Both my flight where delayed Had 25min to make it to my transfer flight

Everything was on time and service on the flight was great!

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

The travel company that you have on your site did me so wrong. I don’t know how it happened, but they put my son‘s name on my plane ticket flying to Vietnam. Along with his birthday. They would not have let me fly from Fort Myers to Ho Chi Minh City. I don’t think that I can ever use your service again. I typed my information into the browser along with my passport number and four days before I’m leaving I have to quickly search another ticket to fly out here.

It was great. Smooth flight, comfortable, left on time and landed on time.

We hoarded. Then we deplaned. Then we waited for 10 hours in the MSP airport due to a wheel misfunction. We understand safety but communication between crew and airport staff was horrible. When we did finally board, we were rushed on and because we were waiting for a “fresh” pilot and crew, we sat in a roasting plane with no A/C for an hour. My question is why was this flight not cancelled right away when they knew this would be a huge issue OR, why did AA not get a substitute plane, considering this was already a full flight? To me, this appears to be a complete breakdown in leadership and utter systems failure. The compensation for completely disrupting travel plans for hundreds, which we paid dearly for, was measly. While we appreciated the lodging for the night, $12 in meal vouchers isn’t going to sustain anyone for over 12 hours. “We apologize; our hands are tied” is no longer an acceptable explanation. We are so completely turned off by this experience and will definitely seek alternative avenues when we need to fly.

Mostly good. The WiFi wasn’t working so that was not great.

I rated the experience "mediocre" because of the 2 hour delay in take off. This is the 4th flight from DFW on AA where there was a delay and in one of the instances (after 13 delays), the flight was cancelled. I understand weather but for the March 18th flight, there was no weather issue in Dallas or Detroit. I called Concierge Key and they were wonderful, booking me on a later flight in case my flight was cancelled. I have flown with American for many years and never has there been this consistent pattern of delays. Very disappointing.

They put me on an earlier and I got home sooner

Not good. One of my luggage is missing. And until now they can’t find it

Horrible experience upon landing. Probably more due to DCA utter incompetence than AA.

Jill was the flight attendant in first class she was fabulous!! Best flight attendant I have had in years.!! And I fly every other week. Other can learn from her!!

Really good. I accidentally left my duffel on the plane and the reps were so friendly in retrieving it.

My 9:50AM flight was delayed to 3:40PM "due to incoming aircraft delay". No aircraft is "delayed" that long. Found out once we did board (after several changes in times) that the aircraft had a maintenance issue and we had to wait for another aircraft. Just tell us that. The aircraft we did get was old and the seats need to be updated. I have been traveling for several weeks with AA and you should refresh your entertainment content as frequent flyers have gone through most of your new content. I have Celiac and a shellfish allergy and continue to have struggles with meals on business and first class flights. Please keep this in mind. Sorry - was a long travel day yesterday and a bit cranky this morning with my experience comments. Still an AA fan.

Everything you need to know for your flight from Missoula to Knoxville

Information on your arrival and departure airports