TYS - ECP

$117 Find Cheap Flights from Knoxville to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Panama City departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$233
Overall average: $366
Southwest
Wed 5/13Wed 5/20
TYS - ECP • 1 stop
Cheapest one-way
$117
Southwest
Wed 3/11
TYS - ECP • 1 stop
Top airlines
Southwest
Cheapest • from $233 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
January
Cheapest • 23% price drop
March
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Panama City (TYS-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Panama City

Wed, May 13 - Wed, May 20
Southwest Logo
2:55 pm - 8:45 pm
TYS
-
ECP
6h 50m
1 stop
Southwest Logo
7:15 am - 12:00 pm
ECP
-
TYS
3h 45m
1 stop
$233Southwest
Wed, May 13 - Wed, May 20
Southwest Logo
2:55 pm - 8:45 pm
TYS
-
ECP
6h 50m
1 stop
Southwest Logo
12:05 pm - 8:50 pm
ECP
-
TYS
7h 45m
2 stops
$238Southwest
Mon, May 4 - Wed, May 6
Southwest Logo
6:35 am - 9:05 am
TYS
-
ECP
3h 30m
1 stop
Southwest Logo
7:15 am - 12:00 pm
ECP
-
TYS
3h 45m
1 stop
$245Southwest
Wed, May 13 - Wed, May 20
Southwest Logo
7:05 am - 4:20 pm
TYS
-
ECP
10h 15m
2 stops
Southwest Logo
10:10 am - 7:40 pm
ECP
-
TYS
8h 30m
2 stops
$249Southwest
Mon, May 4 - Wed, May 6
Southwest Logo
6:35 am - 9:05 am
TYS
-
ECP
3h 30m
1 stop
Southwest Logo
10:10 am - 7:40 pm
ECP
-
TYS
8h 30m
2 stops
$250Southwest
Thu, Mar 26 - Tue, Mar 31
Southwest Logo
3:45 pm - 9:20 pm
TYS
-
ECP
6h 35m
1 stop
Southwest Logo
7:00 am - 11:50 am
ECP
-
TYS
3h 50m
1 stop
$256Southwest
Thu, Mar 26 - Tue, Mar 31
Southwest Logo
3:45 pm - 9:20 pm
TYS
-
ECP
6h 35m
1 stop
Southwest Logo
10:10 am - 8:05 pm
ECP
-
TYS
8h 55m
2 stops
$261Southwest
Wed, Apr 1 - Sun, Apr 5
Southwest Logo
6:35 am - 9:35 am
TYS
-
ECP
4h 00m
1 stop
Southwest Logo
5:25 am - 12:55 pm
ECP
-
TYS
6h 30m
2 stops
$271Southwest
Wed, Apr 1 - Sun, Apr 5
Southwest Logo
6:35 am - 1:10 pm
TYS
-
ECP
7h 35m
2 stops
Southwest Logo
5:25 am - 12:55 pm
ECP
-
TYS
6h 30m
2 stops
$276Southwest
Sat, Jun 6 - Thu, Jun 11
Southwest Logo
6:55 pm - 9:55 pm
TYS
-
ECP
4h 00m
1 stop
Southwest Logo
7:50 am - 12:00 pm
ECP
-
TYS
3h 10m
1 stop
$279Southwest
Booking Insights

KAYAK's insights & trends for Knoxville to Panama City flights

Get data-powered insights and trends into flights from Knoxville to Panama City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Knoxville to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Panama City is January, where tickets cost $302 (return) on average. On the other hand, the most expensive months are April and June, where the average cost of round-trip tickets is $481 and $476 respectively.

Good to know

Low seasonJanuary
Cheapest flight$117
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Knoxville to Panama City

When to book flights from Knoxville to Panama City

Are your dates flexible? Find out the best times to travel from Knoxville to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Panama City

  • What is the cheapest flight from Knoxville to Panama City?

    In the last 3 days, the lowest price for a flight from Knoxville to Panama City was $117 for a one-way ticket and $233 for a round-trip.

  • Do I need a passport to fly between Knoxville and Panama City?

    No, a passport isn't needed to fly from Knoxville to Panama City. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Knoxville to Panama City?

    On your way to Panama City, you’ll fly out from Knoxville McGhee Tyson. You’ll be landing at Panama City NW Florida Beaches.

  • Which aircraft models fly most regularly from Knoxville to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Panama City?

    oneworld, and SkyTeam are the airline alliances operating flights between Knoxville and Panama City, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Panama City, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Panama City are Delta and American Airlines. With an average price for the route of $411 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $484 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Knoxville to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Knoxville to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4295 reviews
8.0Comfort
8.6Crew
7.0Food
8.1Boarding
7.5Entertainment
Airline reviews

The WiFi and crew on the plane were good, however, the boarding experience was awful. I paid for the Choice Preferred and was boarded in group 5 so all overhead storage was full. They found room for our luggage, but further back making getting off the plane a nightmare. Also, we were in row 6 and the seats were extremely uncomfortable. Both my daughter and I had no leg room and couldn’t wait to get off the plane.

4.0 OkayAnonymous, Feb 2026
BOI - LAS
Read more Southwest reviews

The WiFi and crew on the plane were good, however, the boarding experience was awful. I paid for the Choice Preferred and was boarded in group 5 so all overhead storage was full. They found room for our luggage, but further back making getting off the plane a nightmare. Also, we were in row 6 and the seats were extremely uncomfortable. Both my daughter and I had no leg room and couldn’t wait to get off the plane.

Still need to work out the kinks on the new assigned seating boarding process. Otherwise, a very good flight.

Okay, not wonderful. Short flight. Wi-fi didn't work properly. Stuck waiting for a gate to open upon arrival for 20 or so minutes.

They sent a notice that they were boarding an hour early. We had to leave the club and run to the gate. They said sorry, that came from corporate and was a mistake. They did not have enough seating because the flight before it had not taken off on time. They moved our gate and delayed it for an hour.

The quality of Southwest Airlines continues to degrade each time I fly with them. If it were not for the free luggage, I would probably choose another airline. Their prices are a little bit competitive, but way too high for the quality of the service. Southwest is not unique in this way. Domestic flight in the United States of America has continued to be a lower and lower quality product. Very sad when you compare the quality of domestic airlines to that of many international airlines around the world.

Worst experience I had on Southwest. Still better than most, but the seating was barely tolerable.

Cluster mess boarding. Can't wait for SWA reserved seating. Internet didn't seem to work on the plane.

I'm not a fan of Southwest's model. I don't like the herding style of boarding.

It is southwest seat was ok. Not the most comfortable seat

Plz don't take away free bags and free seating

They took all carry-on luggage from Groups 6 -9 - I was group 5 and waiting in line to board - they made me check my luggage too. That then went to baggage claim and delayed departure from the airport. There was overhead room in my seating area - Delta over reacted. Also, had a gentleman next to me that took up 1/2 my seat.

Sorry I didn't realize I was writing a review for each leg. Please see my previous review - it applies to the entire flight, not just a single leg.

boarded at 5:30 pm, pushed away from gate at 6pm ... takeoff was not until ~6:45pm; disappointing

Paid for wifi that didn't work. No plug in seat to work. No entertainment.

The flight was delayed and oversold. I volunteered to give up my seat for compensation. Thinking I could get a good night's sleep instead of arriving home at 2 am. It took over an hour to get the new reservation confirmed, three different gate attendants, and two red coats. It took even longer to confirm the overnight hotel, and when I arrived, the line was 45 minutes long, with two people checking in, and at least 15 people slowly, very slowly—no food except frozen convenience food, no coupon for food from airlines. Slept, headed back to the airport, and that flight had an equipment change and a gate change just as they were about to board. It took an additional hour to board as they cleaned the plane from storage.

No in flight service, no explanation - FC got service, C+ did not, unsure about Economy. No turbulence to speak of, so I guess another way to cut cost, or promote health and well being of Delta employees? Also, boarding in MEM combined zones, and with overhead space already full on both flights after Zone 2/ Diamond, presents a huge challenge to find a space for a bag. Delta, other than point A to B, is no longer reasonable to fly - very poor experiences, not even taking into account the chastising at the gate and rude crews, across the board.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Delta is a good airline. I've never had an issue with Delta. I'll continue to fly with them until they show me that I shouldn't.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

The flight was really crowded. Flight attendants were just ok.

Didn't get a seat assignment until the last minute even though i picked a seat.

Flight was on time and the meal and service were good.

Old equipment, needs upgrade and seat comfort. Internet didn't work 75% or the time.

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

It was a little concerning to hear the ground crew arguing with the flight crew over baggage space. Instead of taking them and checking them, they started checking for space in the first class cabin moving items around like the flight crew didn't know what they were doing. I was embarrassed for them.

On the plus side, crew was attentive, drinks were cold, and in-flight entertainment selection was better than some other airlines. On the negative aide, Plane was delayed almost an hour, either no announcements from the gate crew. Biscoff cookies are gross, appreciate airlines that give a choice. Also, crew had no personality or enthusiasm at all.

UGH I HAD TO MISS MY FIRST FLIGHT TO TAMPA CAUSE OF THE 10 MINUTE DELAY OF THE ORLANDO TO MIAMI ONE SO THEY HAD ME GET ANOTHER TICKET. I AM NOT HAPPY AT ALL BECAUSE IT MADE ME MISS MY CONNECTING FLIGHT FROM TAMPA TO LONDON AND FORCED ME TO MISS A DAY AT MY ROOM IN THE UK.

Wish they didnt delay off-boarding for 10 minutes so i could connect to my flight from miami to tampa

Everything you need to know for your flight from Knoxville to Panama City

Information on your arrival and departure airports