Which airports can I use when flying from Knoxville to Panama City?

Flights from Knoxville to Panama City usually depart from Knoxville McGhee Tyson (TYS) and arrive at Panama City NW Florida Beaches (ECP).

What cabin classes can I book on flights from Knoxville to Panama City?

Only Economy Class is available on flights from Knoxville to Panama City.

Which airports do connecting flights from Knoxville to Panama City pass through?

One-stop flights from Knoxville to Panama City most commonly connect through: • Atlanta Hartsfield-Jackson (ATL) - 56% of one-stop connections • Nashville Intl (BNA) - 32% of one-stop connections • Charlotte Douglas (CLT) - 12% of one-stop connections

Can I save money by using flexible dates for flights from Knoxville to Panama City?

Yes. Flexible dates can save you up to 34% on flights from Knoxville to Panama City. Tuesday is the cheapest departure day at $292 round-trip on average, while Sunday is the most expensive at $438, a difference of $146. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Knoxville to Panama City?

A nonstop flight from Knoxville to Panama City takes 00m, covering 390 miles.

Do I need a passport to fly from Knoxville to Panama City?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Knoxville to Panama City changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $217 to $1,329. That means the highest observed fare was about 6x higher than the lowest one.

How are flight prices from Knoxville to Panama City looking right now?

One-way fares from Knoxville to Panama City are currently lower than usual. Average one-way flight prices are about $240, which is 16% below the typical average for this route.

How much time can I save by choosing a different layover airport from Knoxville to Panama City?

Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 3h 53m, compared with 3h 57m via Atlanta Hartsfield-Jackson (ATL) and 4h 39m via Charlotte Douglas (CLT).

What is the time difference between Knoxville and Panama City?

Panama City is 1 hour behind Knoxville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Panama City NW Florida Beaches Airport (ECP)?

Panama City NW Florida Beaches Airport (ECP) hosts 5 major car rental companies, with daily rates starting from around $32 for economy cars. Top options include: • Dollar • Hertz • Budget • Alamo • Avis

How much should I expect to pay for a Knoxville to Panama City flight?

Round-trip flights from Knoxville to Panama City range from $297 to $458, with an average of $370 over the past 12 months. Anything below $297 counts as a good deal.

How much is a round-trip flight from Knoxville to Panama City?

Round-trip flights from Knoxville to Panama City typically range from $297 to $458. The lowest price found in the past 5 days was $217, on Delta.

What's the cheapest day of the week to fly from Knoxville to Panama City?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Knoxville to Panama City. It’s 22% cheaper than the average day, while Sunday is the most expensive, with prices 18% higher.

What’s the cheapest month to fly from Knoxville to Panama City?

•November is the cheapest month to fly from Knoxville to Panama City at $292 round-trip. •December ($720) and February ($497) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 146% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Which airline is the cheapest to fly from Knoxville to Panama City?

Delta ($217) and Southwest ($252) are the cheapest airlines to fly round-trip from Knoxville to Panama City according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Knoxville to Panama City?

Atlanta Hartsfield-Jackson (ATL) is the most popular layover for the Knoxville to Panama City route. 56% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ATL.

What is the cheapest layover airport when flying from Knoxville to Panama City?

Flights via Nashville Intl (BNA) offer the most affordable fares, with an average round-trip price of $370. Based on KAYAK data over the past 3 months.

When flying from Knoxville to Panama City which airport offers the shortest layover?

Nashville Intl (BNA) had the shortest average connection time for Knoxville to Panama City layovers at 2h 39m over the past 3 months.

$109 CHEAP FLIGHTS from Knoxville to Panama City (TYS - ECP)

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Cheapest round-trip

$217

Typical prices: $297-$458

Delta

Sun 11/11Sun 11/18

TYS - ECP • 1 stop

Cheapest one-way

$109

Typical prices: $179-$343

Delta

Sun 11/4

TYS - ECP • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Knoxville and Panama City. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

November

Cheapest • 21% price drop

August

Most popular

Good to know

Top layover airports

Nashville Intl (BNA)

Cheapest • Avg $370 (round-trip)

Atlanta Hartsfield-Jackson (ATL)

Shortest trip • 3h 57m (one-way)

Insights

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We hope you love your trip to Panama City!

Cheap Flights from Knoxville to Panama City (TYS-ECP)

Cheap flights from Knoxville to Panama City with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Round-trip

One-way

Last minute

Wed, Nov 11 - Wed, Nov 18

5:40 am - 8:45 amTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

4h 05m1 stop Atlanta Hartsfield-Jackson

6:00 am - 9:55 amECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

2h 55m1 stop Atlanta Hartsfield-Jackson

$217Delta

Wed, Nov 4 - Wed, Nov 11

5:40 am - 8:14 amTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

3h 34m1 stop Atlanta Hartsfield-Jackson

6:00 am - 11:28 amECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

4h 28m1 stop Atlanta Hartsfield-Jackson

$230Delta

Wed, Oct 28 - Wed, Nov 4

5:40 am - 8:14 amTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

3h 34m1 stop Atlanta Hartsfield-Jackson

6:00 am - 10:45 amECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

3h 45m1 stop Atlanta Hartsfield-Jackson

$243Delta

Wed, Oct 28 - Wed, Nov 4

8:20 am - 3:30 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

8h 10m2 stops Baltimore/Washington Nashville Intl

7:30 am - 8:50 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

12h 20m2 stops Dallas Love Field Baltimore/Washington

$252Southwest

Sat, Nov 14 - Mon, Nov 16

7:20 pm - 10:52 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

4h 32m1 stop Charlotte Douglas

5:41 pm - 10:48 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

4h 07m1 stop Charlotte Douglas

$259American Airlines

Wed, Nov 11 - Wed, Nov 18

7:14 pm - 10:52 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

4h 38m1 stop Charlotte Douglas

12:00 pm - 6:44 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

5h 44m1 stop Charlotte Douglas

$259American Airlines

Wed, Nov 11 - Wed, Nov 18

7:05 am - 9:30 amTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

3h 25m1 stop Nashville Intl

10:05 am - 7:50 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

8h 45m2 stops Austin Bergstrom Nashville Intl

$317Southwest

Wed, Nov 11 - Wed, Nov 18

7:55 am - 8:35 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

13h 40m2 stops Baltimore/Washington Dallas Love Field

10:05 am - 7:50 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

8h 45m2 stops Austin Bergstrom Nashville Intl

$318Southwest

Tue, Feb 2 - Wed, Feb 3

10:45 am - 9:40 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

11h 55m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

2:56 pm - 9:05 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

29h 09m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$857United Airlines

Tue, Feb 2 - Wed, Feb 3

6:30 am - 9:40 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

16h 10m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

4:40 pm - 2:47 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

21h 07m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

$884United Airlines

Mon, Oct 12 - Thu, Oct 15

6:06 pm - 11:53 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

6h 47m1 stop Charlotte Douglas

7:15 am - 3:12 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

6h 57m1 stop Charlotte Douglas

$682American Airlines

Tue, Oct 13 - Fri, Oct 16

7:13 pm - 10:40 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

4h 27m1 stop Charlotte Douglas

6:42 pm - 11:55 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

4h 13m1 stop Charlotte Douglas

$768American Airlines

Wed, Oct 14 - Sun, Oct 18

7:58 pm - 11:53 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

4h 55m1 stop Charlotte Douglas

7:15 am - 3:12 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

6h 57m1 stop Charlotte Douglas

$768American Airlines

Wed, Oct 14 - Sun, Oct 18

3:20 pm - 8:45 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

6h 25m1 stop Dallas Love Field

7:45 am - 7:05 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

10h 20m2 stops Nashville Intl Orlando

$837Southwest

Tue, Oct 13 - Fri, Oct 16

7:15 am - 5:20 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

11h 05m2 stops Nashville Intl Austin Bergstrom

7:15 am - 12:15 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

4h 00m1 stop Nashville Intl

$843Southwest

Wed, Oct 14 - Sun, Oct 18

7:15 am - 5:20 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

11h 05m2 stops Nashville Intl Austin Bergstrom

7:45 am - 7:05 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

10h 20m2 stops Nashville Intl Orlando

$848Southwest

Tue, Oct 13 - Fri, Oct 16

7:15 am - 5:20 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

11h 05m2 stops Nashville Intl Austin Bergstrom

3:10 pm - 10:45 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

6h 35m2 stops Houston Hobby Nashville Intl

$848Southwest

Mon, Oct 12 - Thu, Oct 15

1:50 pm - 10:15 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

9h 25m1 stop Dallas Love Field

7:15 am - 4:55 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

8h 40m2 stops Nashville Intl Dallas Love Field

$868Southwest

Mon, Oct 12 - Thu, Oct 15

6:06 pm - 11:53 pmTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

6h 47m1 stop Charlotte Douglas

7:15 am - 4:02 pmECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

7h 47m2 stops Charlotte Douglas Chicago O'Hare Intl

$1,056American Airlines

Mon, Oct 12 - Thu, Oct 15

7:25 pm - 11:06 amTYS Knoxville McGhee Tyson-ECP Panama City NW Florida Beaches

16h 41m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

4:57 pm - 9:45 amECP Panama City NW Florida Beaches-TYS Knoxville McGhee Tyson

15h 48m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$1,501United Airlines

Price, demand and travel trends for Knoxville to Panama City flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Knoxville to Panama City? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Panama City departing in november.
What's the cheapest day of the week to fly from Knoxville to Panama City?: Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Knoxville to Panama City. It’s 22% cheaper than the average day, while Sunday is the most expensive, with prices 18% higher.
What’s the cheapest month to fly from Knoxville to Panama City? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Knoxville to Panama City, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •November is the cheapest month to fly from Knoxville to Panama City at $292 round-trip.
•December ($720) and February ($497) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 146% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Low season	January
High season	August
Cheapest flight	$109

Beat the crowds with an average 78% drop in travelers.

The most popular month to fly with an average 84% increase in travelers.

One-way flight from Knoxville to Panama City

When to book flights from Knoxville to Panama City

Are your dates flexible? Find out the best times to travel from Knoxville to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Knoxville to Panama City?
Only Economy Class is available on flights from Knoxville to Panama City.
How long is a flight from Knoxville to Panama City?
A nonstop flight from Knoxville to Panama City takes 00m, covering 390 miles.
Do I need a passport to fly from Knoxville to Panama City?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Knoxville to Panama City flight?
Round-trip flights from Knoxville to Panama City range from $297 to $458, with an average of $370 over the past 12 months. Anything below $297 counts as a good deal.
Have flight prices from Knoxville to Panama City changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $217 to $1,329. That means the highest observed fare was about 6x higher than the lowest one.
How are flight prices from Knoxville to Panama City looking right now?
One-way fares from Knoxville to Panama City are currently lower than usual. Average one-way flight prices are about $240, which is 16% below the typical average for this route.
What car rental options are available at Panama City NW Florida Beaches Airport (ECP)?
Panama City NW Florida Beaches Airport (ECP) hosts 5 major car rental companies, with daily rates starting from around $32 for economy cars. Top options include:

• Dollar
• Hertz
• Budget
• Alamo
• Avis
Which airports can I use when flying from Knoxville to Panama City?
Flights from Knoxville to Panama City usually depart from Knoxville McGhee Tyson (TYS) and arrive at Panama City NW Florida Beaches (ECP).
Which airports do connecting flights from Knoxville to Panama City pass through?
One-stop flights from Knoxville to Panama City most commonly connect through:

• Atlanta Hartsfield-Jackson (ATL) - 56% of one-stop connections
• Nashville Intl (BNA) - 32% of one-stop connections
• Charlotte Douglas (CLT) - 12% of one-stop connections
Can I save money by using flexible dates for flights from Knoxville to Panama City?
Yes. Flexible dates can save you up to 34% on flights from Knoxville to Panama City. Tuesday is the cheapest departure day at $292 round-trip on average, while Sunday is the most expensive at $438, a difference of $146.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Knoxville to Panama City?
Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 3h 53m, compared with 3h 57m via Atlanta Hartsfield-Jackson (ATL) and 4h 39m via Charlotte Douglas (CLT).
What is the time difference between Knoxville and Panama City?
Panama City is 1 hour behind Knoxville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Tuesday departure and avoid flying on Sunday. On this route, Tuesday flights average $292, about $146 less than Sunday fares (33% savings) based on the last 12 months.
If you can choose when to travel, plan your Knoxville to Panama City trip for November. Fares historically average $292 round-trip in that month - typically $428 less than the most expensive month, which is December (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Panama City NW Florida Beaches Airport.

• Hilton Garden Inn Panama City Airport

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TYS - ECP

$109 Find Cheap Flights from Knoxville to Panama City - Compare and Save

Everything you should know

Cheap Flights from Knoxville to Panama City (TYS-ECP)

Cheap flights from Knoxville to Panama City with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Price, demand and travel trends for Knoxville to Panama City flights

How much is a round-trip flight from Knoxville to Panama City?

What's the cheapest day of the week to fly from Knoxville to Panama City?

What’s the cheapest month to fly from Knoxville to Panama City?

Which airline is the cheapest to fly from Knoxville to Panama City?

What’s the most popular layover airport when flying from Knoxville to Panama City?

What is the cheapest layover airport when flying from Knoxville to Panama City?

When flying from Knoxville to Panama City which airport offers the shortest layover?

Key details for Knoxville to Panama City flights

Low season

High season

Cheapest flight

When to book flights from Knoxville to Panama City

Your Knoxville to Panama City flight questions, answered

Your guide to booking Knoxville to Panama City flights

More options for your flight from Knoxville to Panama City

Complete your trip to Panama City with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Knoxville to Panama City

Find direct flights to and from Knoxville and Panama City

Flights from domestic origins to Panama City

Flights to other popular destinations

Find deals for your return flight