ECP - TYS

$128 Find Cheap Flights from Panama City to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Knoxville departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$250
Overall average: $541
Southwest
Fri 5/1Tue 5/5
ECP - TYS • 1 stop
Cheapest one-way
$128
Typical prices: $143-$368
Southwest
Thu 4/9
ECP - TYS • 1 stop
Top airlines
Southwest
Cheapest • from $250 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
October
Cheapest • 29% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Knoxville (ECP-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Knoxville

Fri, May 1 - Tue, May 5
Southwest Logo
6:40 am - 2:10 pm
ECP
-
TYS
6h 30m1 stop
Southwest Logo
8:15 am - 6:55 pm
TYS
-
ECP
11h 40m2 stops
$250Southwest
Fri, May 1 - Tue, May 5
Southwest Logo
9:55 am - 9:15 pm
ECP
-
TYS
10h 20m2 stops
Southwest Logo
8:15 am - 6:55 pm
TYS
-
ECP
11h 40m2 stops
$255Southwest
Fri, Jan 30 - Tue, Feb 3
American Airlines Logo
12:03 pm - 4:49 pm
ECP
-
TYS
3h 46m1 stop
American Airlines Logo
8:09 am - 11:33 am
TYS
-
ECP
4h 24m1 stop
$278American Airlines
Fri, May 1 - Mon, May 4
Southwest Logo
6:40 am - 2:10 pm
ECP
-
TYS
6h 30m1 stop
Southwest Logo
6:35 am - 9:05 am
TYS
-
ECP
3h 30m1 stop
$279Southwest
Fri, May 1 - Mon, May 4
Southwest Logo
9:55 am - 9:15 pm
ECP
-
TYS
10h 20m2 stops
Southwest Logo
6:35 am - 9:05 am
TYS
-
ECP
3h 30m1 stop
$284Southwest
Fri, May 1 - Mon, May 4
Southwest Logo
9:55 am - 9:15 pm
ECP
-
TYS
10h 20m2 stops
Southwest Logo
6:35 am - 4:15 pm
TYS
-
ECP
10h 40m2 stops
$295Southwest
Wed, Apr 1 - Wed, Apr 8
Delta Logo
9:25 am - 4:06 pm
ECP
-
TYS
5h 41m1 stop
Delta Logo
5:30 am - 8:39 am
TYS
-
ECP
4h 09m1 stop
$307Delta
Fri, Mar 6 - Wed, Mar 11
American Airlines Logo
3:00 pm - 10:45 am
ECP
-
TYS
18h 45m1 stop
American Airlines Logo
7:02 am - 10:06 am
TYS
-
ECP
4h 04m1 stop
$318American Airlines
Fri, Jan 30 - Tue, Feb 3
American Airlines Logo
6:03 pm - 12:46 pm
ECP
-
TYS
17h 43m2 stops
American Airlines Logo
8:09 am - 11:33 am
TYS
-
ECP
4h 24m1 stop
$323American Airlines
Wed, Feb 4 - Sun, Feb 8
American Airlines Logo
6:03 pm - 10:54 pm
ECP
-
TYS
3h 51m1 stop
American Airlines Logo
6:05 am - 11:33 am
TYS
-
ECP
6h 28m1 stop
$343American Airlines
Booking Insights

KAYAK's insights & trends for Panama City to Knoxville flights

Get data-powered insights and trends into flights from Panama City to Knoxville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City, Florida to Knoxville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City, Florida to Knoxville departing in May.

What is the cheapest month to fly from Panama City to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Knoxville is October, where tickets cost $326 (return) on average. On the other hand, the most expensive months are January and March, where the average cost of round-trip tickets is $608 and $556 respectively.

Good to know

Low seasonMarch
Cheapest flight$128
Best time to beat the crowds but there is an average 20% increase in price.
Most popular time to fly with an average 2% increase in price.
Flight from Panama City to Knoxville

When to book flights from Panama City to Knoxville

Are your dates flexible? Find out the best times to travel from Panama City to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Knoxville

  • What is the cheapest flight from Panama City to Knoxville?

    In the last 3 days, the lowest price for a flight from Panama City to Knoxville was $128 for a one-way ticket and $250 for a round-trip.

  • Do I need a passport to fly between Panama City and Knoxville?

    A passport is not required to fly from Panama City to Knoxville.

  • Which airports will I be using when flying from Panama City to Knoxville?

    Panama City and Knoxville are both served by 1 main airport. You will leave Panama City from Panama City NW Florida Beaches and will be arriving at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Panama City to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to Knoxville?

    oneworld, and SkyTeam are the airline alliances operating flights between Panama City and Knoxville, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Panama City to Knoxville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Knoxville are Delta and American Airlines. With an average price for the route of $413 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $445 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Panama City to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Panama City with another airline. Booking your flights between Panama City and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Panama City to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8018 reviews
7.9Comfort
7.8Entertainment
7.2Food
8.1Boarding
8.5Crew
Airline reviews

The only thing nice I can say is the flight crew was really nice and apologetic about the situation. They shared as much information as they had and advised us on what we could do about missing connecting flights. The boarding process was so slow. The gate agent was working by herself and should have had someone working with her. It took almost an hour to board because she was trying to board a full flight of people and provide customer service to everyone who was flying standby and/or had questions. It was really chaotic. This didn't help the fact that we were delayed and folks were missing connections the longer it took.

4.0 OkayLaToya, Dec 2025
MCO - ATL
Read more Delta reviews

The only thing nice I can say is the flight crew was really nice and apologetic about the situation. They shared as much information as they had and advised us on what we could do about missing connecting flights. The boarding process was so slow. The gate agent was working by herself and should have had someone working with her. It took almost an hour to board because she was trying to board a full flight of people and provide customer service to everyone who was flying standby and/or had questions. It was really chaotic. This didn't help the fact that we were delayed and folks were missing connections the longer it took.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Boarding was organized and timely. Food was mediocre, especially for first class travel.

We were 4+ hours delayed. AA is absolutely obnoxious. They just kept pushing back the time to the point where we did not get into Vegas until after midnight when we were supposed to arrive like 845pm.

My last flight on 25 Dec, it’s Christmas Day, everyone happy and very good mood. I really enjoy traveling with Americans Airlines from Miami to Minneapolis my home town after long flight from lhe to Doha then Miami. Thank you again to make my travels comfortable and relaxed. Best regards

For whatever reason, the flight was not catered -we were told it would be a 45 minute delay waiting for catering - so no food. There were opened candy and peanuts in the seatback pocket. Flight landed early in DFW but due to the assigned gate not being available, we sat on the ground for 30 minutes waiting for the gate to open - making the flight actually arrive at the gate late.

The pilot greased the landing and the crew was fantastic.

delayed due to weather. Could not communicate with family since the wifi was broken

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

I appreciated that it was on time, safe and professional. I didn’t like that I wasn’t in a place where I had a window at my window seat. It would have been nice to know that in advance. If it was mentioned in the ticketing, I didn’t notice it.

I like that the crew kept us informed but we moved back and forth from gate to gate before the aircraft arrived.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Everything you need to know for your flight from Panama City to Knoxville

Information on your arrival and departure airports