TYS - SAT

$152 Find Cheap Flights from Knoxville to San Antonio - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$296
Typical prices: $294-$437
Multiple Airlines
Tue 11/6Wed 11/14
TYS - SAT • 2 stops
Cheapest one-way
$152
Typical prices: $188-$349
United Airlines
Sun 9/23
TYS - SAT • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Knoxville and San Antonio. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 16% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Denver Intl (DEN)
Cheapest • Avg $262 (round-trip)
Houston George Bush Intcntl (IAH)
Shortest trip • 5h 01m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to San Antonio (TYS-SAT)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to San Antonio

Fri, Nov 6 - Sat, Nov 14
Multiple Airlines Logo
1:17 pm - 8:45 amTYS  Knoxville McGhee Tyson-SAT San Antonio
44h 28m2 stops Philadelphia Raleigh-Durham
Multiple Airlines Logo
8:20 pm - 1:19 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
15h 59m1 stop Denver Intl
$296Multiple Airlines
Thu, Jan 7 - Sat, Jan 9
United Airlines Logo
7:00 am - 1:03 pmTYS  Knoxville McGhee Tyson-SAT San Antonio
7h 03m1 stop Houston George Bush Intcntl
United Airlines Logo
6:43 am - 1:18 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
5h 35m1 stop Chicago O'Hare Intl
$303United Airlines
Tue, Sep 15 - Tue, Sep 22
American Airlines Logo
6:00 am - 10:01 amTYS  Knoxville McGhee Tyson-SAT San Antonio
5h 01m1 stop Dallas/Fort Worth
American Airlines Logo
6:00 am - 1:53 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
6h 53m1 stop Dallas/Fort Worth
$303American Airlines
Tue, Sep 15 - Tue, Sep 22
American Airlines Logo
6:00 am - 10:01 amTYS  Knoxville McGhee Tyson-SAT San Antonio
5h 01m1 stop Dallas/Fort Worth
American Airlines Logo
6:00 am - 1:53 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
6h 53m1 stop Dallas/Fort Worth
$303American Airlines
Tue, Oct 13 - Tue, Oct 20
Delta Logo
6:23 pm - 12:33 amTYS  Knoxville McGhee Tyson-SAT San Antonio
7h 10m1 stop Atlanta Hartsfield-Jackson
Delta Logo
1:41 pm - 8:08 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
5h 27m1 stop Atlanta Hartsfield-Jackson
$303Delta
Tue, Oct 13 - Sat, Oct 24
Delta Logo
6:23 pm - 12:33 amTYS  Knoxville McGhee Tyson-SAT San Antonio
7h 10m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:50 am - 1:31 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
5h 41m1 stop Atlanta Hartsfield-Jackson
$303Delta
Wed, Oct 21 - Mon, Oct 26
United Airlines Logo
7:15 am - 10:43 amTYS  Knoxville McGhee Tyson-SAT San Antonio
4h 28m1 stop Houston George Bush Intcntl
United Airlines Logo
2:20 pm - 9:57 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
6h 37m1 stop Houston George Bush Intcntl
$303United Airlines
Wed, Nov 4 - Wed, Nov 11
Southwest Logo
4:15 pm - 9:40 pmTYS  Knoxville McGhee Tyson-SAT San Antonio
6h 25m1 stop Denver Intl
Southwest Logo
12:00 pm - 8:45 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
7h 45m2 stops Dallas Love Field Baltimore/Washington
$308Southwest
Fri, Oct 23 - Mon, Oct 26
Southwest Logo
7:25 pm - 12:40 amTYS  Knoxville McGhee Tyson-SAT San Antonio
6h 15m1 stop Nashville Intl
Southwest Logo
5:00 am - 1:10 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
7h 10m1 stop Orlando
$321Southwest
Thu, Sep 17 - Sun, Sep 20
Multiple Airlines Logo
7:00 am - 7:25 pmTYS  Knoxville McGhee Tyson-SAT San Antonio
13h 25m1 stop Denver Intl
Multiple Airlines Logo
9:25 am - 8:39 pmSAT  San Antonio-TYS Knoxville McGhee Tyson
34h 14m2 stops Raleigh-Durham Orlando
$335Multiple Airlines
Booking Insights

Price, demand and travel trends for Knoxville to San Antonio flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Knoxville to San Antonio with more confidence.

What's the cheapest day of the week to fly from Knoxville to San Antonio?

Saturday is the cheapest day of the week to fly from Knoxville to San Antonio, it is 20% cheaper than the average day. Monday is the most expensive day with flight prices 29% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Knoxville to San Antonio?

  • January is the cheapest month to fly from Knoxville to San Antonio at $290 round-trip.
  • July ($578) and June ($488) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 99% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Knoxville to San Antonio flights

Low season

August

Cheapest flight

$152
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 12% increase in price.
Flight from Knoxville to San Antonio

When to book flights from Knoxville to San Antonio

Are your dates flexible? Find out the best times to travel from Knoxville to San Antonio based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to San Antonio flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Knoxville to San Antonio?

    Flights from Knoxville to San Antonio usually depart from Knoxville McGhee Tyson (TYS) and arrive at San Antonio (SAT).

  • What cabin classes can I book on flights from Knoxville to San Antonio?

    Two cabin classes are available on flights from Knoxville to San Antonio:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Knoxville to San Antonio pass through?

    One-stop flights from Knoxville to San Antonio most commonly connect through:

    • Dallas/Fort Worth (DFW) - 39% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 24% of one-stop connections
    • Houston George Bush Intcntl (IAH) - 22% of one-stop connections
    • Nashville Intl (BNA) - 10% of one-stop connections

    Dallas/Fort Worth (DFW) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Knoxville to San Antonio?

    On the Knoxville to San Antonio route, being flexible with your departure day can save you up to 38%. Saturday is the cheapest day at $280 round-trip on average, while Monday is the most expensive at $448: a $168 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • What popular places can I visit in San Antonio?

    Some of the most popular sights in San Antonio are San Antonio River Walk, SeaWorld San Antonio and Henry B. González Convention Center. These are among the most viewed places in San Antonio on KAYAK.

  • How long is a flight from Knoxville to San Antonio?

    A nonstop flight from Knoxville to San Antonio takes 0h 00m, covering 945 miles.

  • Do I need a passport to fly from Knoxville to San Antonio?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Knoxville to San Antonio changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $277 to $906. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Knoxville to San Antonio looking right now?

    One-way fares from Knoxville to San Antonio are currently lower than usual. Average one-way flight prices are about $164, which is 32% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Knoxville to San Antonio?

    Flying via Houston George Bush Intcntl (IAH) gives the shortest average 1-stop total travel time at 5h 01m, compared with 5h 01m via Nashville Intl (BNA) and 5h 09m via Dallas/Fort Worth (DFW).

  • What is the time difference between Knoxville and San Antonio?

    San Antonio is 1 hour behind Knoxville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at San Antonio Airport (SAT)?

    San Antonio Airport (SAT) hosts 5 major car rental companies, with daily rates starting from around $22 for economy cars. Top options include:
    · Europcar
    · Fox
    · Dollar
    · Hertz
    · Alamo

  • How much should I expect to pay for a Knoxville to San Antonio flight?

    Round-trip flights from Knoxville to San Antonio range from $294 to $437, with an average of $346 over the past 12 months. Anything below $294 counts as a good deal.

Your guide to booking Knoxville to San Antonio flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Saturday departure instead of Monday. On this route, Saturday flights average $280 - about $168 less than Monday (38% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Knoxville to San Antonio trip for January. Fares historically average $290 round-trip in that month - typically $288 less than the most expensive month, which is July (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Antonio Airport.
    - Wyndham Garden San Antonio Airport
    - Crowne Plaza San Antonio Airport By IHG
    - Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Everything you need to know for your flight from Knoxville to San Antonio

Information on your arrival and departure airports

Knoxville (TYS)
San Antonio (SAT)