Which airports can I use when flying from San Antonio to Knoxville?

Flights from San Antonio to Knoxville usually depart from San Antonio (SAT) and arrive at Knoxville McGhee Tyson (TYS).

What cabin classes can I book on flights from San Antonio to Knoxville?

Two cabin classes are available on flights from San Antonio to Knoxville: • Economy Class • First Class

Which airports do connecting flights from San Antonio to Knoxville pass through?

One-stop flights from San Antonio to Knoxville most commonly connect through: • Atlanta Hartsfield-Jackson (ATL) - 49% of one-stop connections • Dallas/Fort Worth (DFW) - 35% of one-stop connections • Nashville Intl (BNA) - 7% of one-stop connections • Dallas Love Field (DAL) - 4% of one-stop connections Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

Can I save money by using flexible dates for flights from San Antonio to Knoxville?

Yes. Being flexible with your travel dates can save you up to 37% on the San Antonio to Knoxville route. Wednesday is the cheapest departure day at $277 round-trip on average, while Friday is the most expensive at $438, a difference of $161. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How expensive are last-minute San Antonio to Knoxville flights?

Last-minute fares on this route - booked within 2 weeks of departure - run 49% above the route average of $367. Book 25 weeks before departure for the lowest fares.

How long is a flight from San Antonio to Knoxville?

A nonstop flight from San Antonio to Knoxville takes 0h 00m, covering 945 miles.

Do I need a passport to fly from San Antonio to Knoxville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from San Antonio to Knoxville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $264 to $990. That means the highest observed fare was about 4x higher than the lowest one.

How are flight prices from San Antonio to Knoxville looking right now?

One-way fares from San Antonio to Knoxville are currently lower than usual. Average one-way flight prices are about $156, which is 30% below the typical average for this route.

How much time can I save by choosing a different layover airport from San Antonio to Knoxville?

Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 4h 40m, compared with 4h 41m via Dallas Love Field (DAL) and 4h 54m via Houston George Bush Intcntl (IAH).

What is the time difference between San Antonio and Knoxville?

Knoxville is 1 hour ahead of San Antonio (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include: · Budget · Alamo · Thrifty · Enterprise Rent-A-Car · Payless

How much should I expect to pay for a San Antonio to Knoxville flight?

Round-trip flights from San Antonio to Knoxville range from $288 to $474, with an average of $367 over the past 12 months. Anything below $288 counts as a good deal.

What is the cheapest airline to fly from San Antonio to Knoxville?

American Airlines ($303) and Southwest ($303) are the cheapest airlines to fly round-trip from San Antonio to Knoxville according to KAYAK data over the last 5 days.

What is the most popular layover airport when flying from San Antonio to Knoxville?

Atlanta Hartsfield-Jackson (ATL) is the most popular layover for the San Antonio to Knoxville route. 49% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ATL.

What is the cheapest layover airport when flying from San Antonio to Knoxville?

Flights via Detroit Metropolitan Wayne County (DTW) offer the most affordable fares, with an average round-trip price of $251. Based on KAYAK data over the past 3 months.

When flying from San Antonio to Knoxville which airport offers the shortest layover?

Dallas/Fort Worth (DFW) had the shortest average connection time for San Antonio to Knoxville layovers at 178 minutes over the past 3 months.

$107 CHEAP FLIGHTS from San Antonio to Knoxville (SAT - TYS)

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$207

Typical prices: $288-$474

Multiple Airlines

Tue 10/2Thu 10/4

SAT - TYS • 1 stop

Cheapest one-way

$107

Typical prices: $194-$328

Multiple Airlines

Tue 10/2

SAT - TYS • 1 stop

Nonstop flights

Not available

There are currently no direct flights between San Antonio and Knoxville. You'll need to take a connecting flight to reach the destination.

Insights

When to book

25 weeks

in advance

Our data shows that travelers who book at least 25 weeks in advance save around 56% compared to booking last minute.

Insights

When to travel

May

Cheapest • 21% price drop

November

Most popular

Good to know

Top layover airports

Detroit Metropolitan Wayne County (DTW)

Cheapest • Avg $251 (round-trip)

Nashville Intl (BNA)

Shortest trip • 4h 40m (one-way)

Insights

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Knoxville!

Flight Deals

Cheap Flights from San Antonio to Knoxville (SAT-TYS)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from San Antonio to Knoxville

Thu, Oct 1 - Sun, Oct 4

9:25 am - 11:59 amSAT San Antonio-TYS Knoxville McGhee Tyson

25h 34m2 stops Raleigh-Durham Orlando

6:11 pm - 11:58 amTYS Knoxville McGhee Tyson-SAT San Antonio

18h 47m1 stop Memphis

$264Multiple Airlines

Mon, Nov 2 - Tue, Nov 3

9:45 am - 3:00 pmSAT San Antonio-TYS Knoxville McGhee Tyson

4h 15m1 stop Dallas Love Field

5:15 pm - 11:05 pmTYS Knoxville McGhee Tyson-SAT San Antonio

6h 50m1 stop Nashville Intl

$303Southwest

Tue, Oct 20 - Tue, Oct 27

1:41 pm - 8:08 pmSAT San Antonio-TYS Knoxville McGhee Tyson

5h 27m1 stop Atlanta Hartsfield-Jackson

6:23 pm - 12:33 amTYS Knoxville McGhee Tyson-SAT San Antonio

7h 10m1 stop Atlanta Hartsfield-Jackson

$303Delta

Wed, Nov 4 - Mon, Nov 9

5:30 am - 10:45 amSAT San Antonio-TYS Knoxville McGhee Tyson

4h 15m1 stop Atlanta Hartsfield-Jackson

6:07 pm - 12:33 amTYS Knoxville McGhee Tyson-SAT San Antonio

7h 26m1 stop Atlanta Hartsfield-Jackson

$303Delta

Tue, Sep 22 - Tue, Sep 29

5:00 am - 11:17 amSAT San Antonio-TYS Knoxville McGhee Tyson

5h 17m1 stop Dallas/Fort Worth

6:00 am - 10:01 amTYS Knoxville McGhee Tyson-SAT San Antonio

5h 01m1 stop Dallas/Fort Worth

$303American Airlines

Tue, Sep 15 - Tue, Sep 22

8:55 am - 5:31 pmSAT San Antonio-TYS Knoxville McGhee Tyson

7h 36m1 stop Charlotte Douglas

5:35 pm - 10:50 pmTYS Knoxville McGhee Tyson-SAT San Antonio

6h 15m1 stop Dallas/Fort Worth

$303American Airlines

Mon, Nov 2 - Tue, Nov 3

9:45 am - 3:00 pmSAT San Antonio-TYS Knoxville McGhee Tyson

4h 15m1 stop Dallas Love Field

5:15 pm - 9:40 pmTYS Knoxville McGhee Tyson-SAT San Antonio

5h 25m2 stops Nashville Intl Dallas Love Field

$308Southwest

Fri, Sep 25 - Sun, Sep 27

12:38 pm - 8:09 pmSAT San Antonio-TYS Knoxville McGhee Tyson

6h 31m1 stop Memphis

5:38 pm - 11:58 amTYS Knoxville McGhee Tyson-SAT San Antonio

19h 20m1 stop Memphis

$325Multiple Airlines

Sat, Sep 19 - Mon, Sep 21

4:12 pm - 9:45 pmSAT San Antonio-TYS Knoxville McGhee Tyson

4h 33m1 stop Houston George Bush Intcntl

6:02 pm - 10:51 pmTYS Knoxville McGhee Tyson-SAT San Antonio

5h 49m1 stop Chicago O'Hare Intl

$327United Airlines

Tue, Sep 15 - Tue, Sep 22

7:35 am - 4:58 pmSAT San Antonio-TYS Knoxville McGhee Tyson

8h 23m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

6:00 pm - 10:51 pmTYS Knoxville McGhee Tyson-SAT San Antonio

5h 51m1 stop Chicago O'Hare Intl

$332United Airlines

Recent last minute flight deals from San Antonio to Knoxville

Sun, Aug 30 - Thu, Sep 17

9:55 am - 7:03 pmSAT San Antonio-TYS Knoxville McGhee Tyson

32h 08m2 stops Raleigh-Durham Orlando

7:00 am - 7:25 pmTYS Knoxville McGhee Tyson-SAT San Antonio

13h 25m1 stop Denver Intl

$393Multiple Airlines

Sun, Aug 30 - Mon, Sep 21

9:55 am - 7:03 pmSAT San Antonio-TYS Knoxville McGhee Tyson

32h 08m2 stops Raleigh-Durham Orlando

6:30 am - 9:03 pmTYS Knoxville McGhee Tyson-SAT San Antonio

15h 33m1 stop Las Vegas Harry Reid Intl

$441Multiple Airlines

Sat, Aug 29 - Thu, Sep 17

2:43 pm - 8:10 pmSAT San Antonio-TYS Knoxville McGhee Tyson

4h 27m1 stop Atlanta Hartsfield-Jackson

7:25 pm - 12:08 amTYS Knoxville McGhee Tyson-SAT San Antonio

5h 43m1 stop Atlanta Hartsfield-Jackson

$446Delta

Sat, Aug 29 - Mon, Sep 21

2:43 pm - 10:39 pmSAT San Antonio-TYS Knoxville McGhee Tyson

6h 56m1 stop Atlanta Hartsfield-Jackson

7:25 pm - 12:08 amTYS Knoxville McGhee Tyson-SAT San Antonio

5h 43m1 stop Atlanta Hartsfield-Jackson

$446Delta

Mon, Aug 31 - Mon, Sep 14

11:34 am - 6:17 pmSAT San Antonio-TYS Knoxville McGhee Tyson

5h 43m1 stop Houston George Bush Intcntl

3:40 pm - 9:16 pmTYS Knoxville McGhee Tyson-SAT San Antonio

6h 36m1 stop Houston George Bush Intcntl

$532United Airlines

Sat, Aug 29 - Wed, Sep 2

6:00 am - 12:58 pmSAT San Antonio-TYS Knoxville McGhee Tyson

5h 58m1 stop Dallas/Fort Worth

7:19 am - 11:49 amTYS Knoxville McGhee Tyson-SAT San Antonio

5h 30m1 stop Dallas/Fort Worth

$589American Airlines

Sat, Aug 29 - Wed, Sep 2

5:30 am - 4:58 pmSAT San Antonio-TYS Knoxville McGhee Tyson

10h 28m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

10:40 am - 4:31 pmTYS Knoxville McGhee Tyson-SAT San Antonio

6h 51m1 stop Chicago O'Hare Intl

$594United Airlines

Sat, Aug 29 - Wed, Sep 2

6:10 am - 1:15 pmSAT San Antonio-TYS Knoxville McGhee Tyson

6h 05m2 stops Houston Hobby Dallas Love Field

7:00 am - 2:35 pmTYS Knoxville McGhee Tyson-SAT San Antonio

8h 35m2 stops Nashville Intl Dallas Love Field

$599Southwest

Mon, Aug 31 - Fri, Sep 18

6:00 am - 12:20 pmSAT San Antonio-TYS Knoxville McGhee Tyson

5h 20m2 stops Houston Hobby Nashville Intl

7:10 am - 2:15 pmTYS Knoxville McGhee Tyson-SAT San Antonio

8h 05m2 stops Nashville Intl Atlanta Hartsfield-Jackson

$620Southwest

Thu, Aug 27 - Sun, Aug 30

8:55 am - 5:34 pmSAT San Antonio-TYS Knoxville McGhee Tyson

7h 39m1 stop Charlotte Douglas

1:46 pm - 6:39 pmTYS Knoxville McGhee Tyson-SAT San Antonio

5h 53m1 stop Dallas/Fort Worth

$681American Airlines

Booking Insights

Price, demand and travel trends for San Antonio to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from San Antonio to Knoxville with more confidence.

Prices

Airlines

Layovers

What's the cheapest day of the week to fly from San Antonio to Knoxville?

Wednesday is the cheapest day of the week to fly from San Antonio to Knoxville, it is 25% cheaper than the average day. Friday is the most expensive day with flight prices 19% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from San Antonio to Knoxville?

May is the cheapest month to fly from San Antonio to Knoxville at $292 round-trip.
March ($518) and April ($478) are the most expensive months.
The price difference between flying in the cheapest and most expensive months is 77% on average.

This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from San Antonio to Knoxville the cheapest?

Flights from San Antonio to Knoxville are cheapest 25 weeks before departure. Booking in this window typically costs about 56% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Low season	February
High season	November
Cheapest flight	$107

Best time to beat the crowds with an average 4% drop in price.

Most popular time to fly and prices are also 3% lower on average.

Flight from San Antonio to Knoxville

When to book flights from San Antonio to Knoxville

Are your dates flexible? Find out the best times to travel from San Antonio to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from San Antonio to Knoxville?
Flights from San Antonio to Knoxville usually depart from San Antonio (SAT) and arrive at Knoxville McGhee Tyson (TYS).
What cabin classes can I book on flights from San Antonio to Knoxville?
Two cabin classes are available on flights from San Antonio to Knoxville:

• Economy Class
• First Class
Which airports do connecting flights from San Antonio to Knoxville pass through?
One-stop flights from San Antonio to Knoxville most commonly connect through:

• Atlanta Hartsfield-Jackson (ATL) - 49% of one-stop connections
• Dallas/Fort Worth (DFW) - 35% of one-stop connections
• Nashville Intl (BNA) - 7% of one-stop connections
• Dallas Love Field (DAL) - 4% of one-stop connections

Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.
Can I save money by using flexible dates for flights from San Antonio to Knoxville?
Yes. Being flexible with your travel dates can save you up to 37% on the San Antonio to Knoxville route. Wednesday is the cheapest departure day at $277 round-trip on average, while Friday is the most expensive at $438, a difference of $161. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How expensive are last-minute San Antonio to Knoxville flights?
Last-minute fares on this route - booked within 2 weeks of departure - run 49% above the route average of $367. Book 25 weeks before departure for the lowest fares.
How long is a flight from San Antonio to Knoxville?
A nonstop flight from San Antonio to Knoxville takes 0h 00m, covering 945 miles.
Do I need a passport to fly from San Antonio to Knoxville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
Have flight prices from San Antonio to Knoxville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $264 to $990. That means the highest observed fare was about 4x higher than the lowest one.
How are flight prices from San Antonio to Knoxville looking right now?
One-way fares from San Antonio to Knoxville are currently lower than usual. Average one-way flight prices are about $156, which is 30% below the typical average for this route.
How much time can I save by choosing a different layover airport from San Antonio to Knoxville?
Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 4h 40m, compared with 4h 41m via Dallas Love Field (DAL) and 4h 54m via Houston George Bush Intcntl (IAH).
What is the time difference between San Antonio and Knoxville?
Knoxville is 1 hour ahead of San Antonio (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?
Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
· Budget
· Alamo
· Thrifty
· Enterprise Rent-A-Car
· Payless
How much should I expect to pay for a San Antonio to Knoxville flight?
Round-trip flights from San Antonio to Knoxville range from $288 to $474, with an average of $367 over the past 12 months. Anything below $288 counts as a good deal.

If your dates can be flexible, aim for a Wednesday departure instead of Friday. On this route, Wednesday flights average $277 - about $161 less than Friday (37% savings) based on the last 12 months.
For the best chance at a low fare, aim to book around 25 weeks before you fly. On this route, that window historically saves about 56% versus last-minute pricing (KAYAK booking data, last 12 months).
If you can choose when to travel, plan your San Antonio to Knoxville trip for May. Fares historically average $292 round-trip in that month - typically $226 less than the most expensive month, which is March (based on the last 12 months).

Everything you need to know for your flight from San Antonio to Knoxville

Airports

Cabin class

Complete your trip

Direct Flights

Flights to other cities

Origins

Other airports

Return flight deals

Information on your arrival and departure airports

San Antonio (SAT)

Knoxville (TYS)

SAT - TYS

$107 Find Cheap Flights from San Antonio to Knoxville - Compare and Save

Everything you should know

Cheap Flights from San Antonio to Knoxville (SAT-TYS)

Recent round-trip flight deals from San Antonio to Knoxville

Recent one-way flight deals from San Antonio to Knoxville

Recent last minute flight deals from San Antonio to Knoxville

Price, demand and travel trends for San Antonio to Knoxville flights

What's the cheapest day of the week to fly from San Antonio to Knoxville?

What is the cheapest month to fly from San Antonio to Knoxville?

When are prices from San Antonio to Knoxville the cheapest?

What is the cheapest airline to fly from San Antonio to Knoxville?

What is the most popular layover airport when flying from San Antonio to Knoxville?

What is the cheapest layover airport when flying from San Antonio to Knoxville?

When flying from San Antonio to Knoxville which airport offers the shortest layover?

Key details for San Antonio to Knoxville flights

Low season

High season

Cheapest flight

When to book flights from San Antonio to Knoxville

Your San Antonio to Knoxville flight questions, answered

Your guide to booking San Antonio to Knoxville flights

Everything you need to know for your flight from San Antonio to Knoxville

Information on your arrival and departure airports

Cabin class types available on flights from San Antonio to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Find direct flights to and from San Antonio and Knoxville

Flights to other popular destinations

Flights from domestic origins to Knoxville

Choose which airport to fly into in Knoxville

Find deals for your return flight