SAT - TYS

$145 Find Cheap Flights from San Antonio to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Antonio to Knoxville departing on 6/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Antonio to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Antonio to Knoxville, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$267
Typical prices: $449-$294
American Airlines
Wed 9/2Sat 9/5
SAT - TYS • 1 stop
Cheapest one-way
$145
Typical prices: $169-$287
Frontier
Thu 6/18
SAT - TYS • 1 stop
Top airlines
Cheapest • from $267 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between San Antonio and Knoxville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $251 (round-trip)
Shortest trip • 4h 16m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 17% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 21% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Antonio to Knoxville (SAT-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Antonio to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Antonio to Knoxville

Wed, Sep 2 - Sat, Sep 5
American Airlines Logo
12:29 pm - 7:00 pm
SAT
-
TYS
5h 31m
1 stop
American Airlines Logo
6:50 pm - 10:54 pm
TYS
-
SAT
5h 04m
1 stop
$267American Airlines
Thu, Jul 16 - Wed, Jul 22
Frontier Logo
7:49 pm - 7:24 pm
SAT
-
TYS
22h 35m
1 stop
Frontier Logo
8:19 pm - 6:54 pm
TYS
-
SAT
23h 35m
1 stop
$271Frontier
Tue, Oct 20 - Tue, Oct 27
Southwest Logo
11:55 am - 6:30 pm
SAT
-
TYS
5h 35m
1 stop
Southwest Logo
7:00 am - 10:15 am
TYS
-
SAT
4h 15m
1 stop
$277Southwest
Thu, Jun 18 - Mon, Jun 22
Frontier Logo
7:51 pm - 7:37 pm
SAT
-
TYS
22h 46m
1 stop
Frontier Logo
8:32 pm - 6:56 pm
TYS
-
SAT
23h 24m
1 stop
$278Frontier
Tue, Jun 23 - Tue, Jun 30
Delta Logo
5:25 am - 11:09 am
SAT
-
TYS
4h 44m
1 stop
Delta Logo
5:40 am - 11:10 am
TYS
-
SAT
6h 30m
1 stop
$279Delta
Thu, Jul 16 - Wed, Jul 22
Frontier Logo
7:49 pm - 7:24 pm
SAT
-
TYS
22h 35m
1 stop
Frontier Logo
8:19 pm - 6:54 pm
TYS
-
SAT
23h 35m
1 stop
$280Frontier
Tue, Jul 28 - Tue, Aug 4
Southwest Logo
6:10 am - 2:05 pm
SAT
-
TYS
6h 55m
2 stops
Southwest Logo
7:00 am - 10:20 am
TYS
-
SAT
4h 20m
1 stop
$282Southwest
Tue, Jul 28 - Tue, Aug 4
Southwest Logo
12:05 pm - 8:25 pm
SAT
-
TYS
7h 20m
2 stops
Southwest Logo
7:00 am - 12:50 pm
TYS
-
SAT
6h 50m
2 stops
$287Southwest
Fri, Sep 25 - Sun, Sep 27
Multiple Airlines Logo
12:38 pm - 8:09 pm
SAT
-
TYS
6h 31m
1 stop
Multiple Airlines Logo
5:38 pm - 11:58 am
TYS
-
SAT
19h 20m
1 stop
$288Multiple Airlines
Sat, Oct 3 - Tue, Oct 13
Delta Logo
8:00 am - 2:50 pm
SAT
-
TYS
5h 50m
1 stop
Delta Logo
7:20 pm - 12:28 am
TYS
-
SAT
6h 08m
1 stop
$289Delta
Booking Insights

KAYAK's insights & trends for San Antonio to Knoxville flights

Get data-powered insights and trends into flights from San Antonio to Knoxville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from San Antonio to Knoxville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from San Antonio to Knoxville departing in September.

What is the cheapest month to fly from San Antonio to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Antonio to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Antonio to Knoxville is January, where tickets cost $283 (return) on average. On the other hand, the most expensive months are April and March, where the average cost of round-trip tickets is $483 and $433 respectively.

How far in advance should I book a flight from San Antonio to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Antonio to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Antonio to Knoxville, you should book around 5 weeks before departure, which saves you about 17% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Good to know

Low seasonMarch
Cheapest flight$145
Best time to beat the crowds but there is an average 20% increase in price.
Most popular time to fly and prices are also 22% lower on average.
Flight from San Antonio to Knoxville

When to book flights from San Antonio to Knoxville

Are your dates flexible? Find out the best times to travel from San Antonio to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Antonio to Knoxville

  • What is the cheapest flight from San Antonio to Knoxville?

    In the last 7 days, the lowest price for a flight from San Antonio to Knoxville was $145 for a one-way ticket and $267 for a round-trip.

  • Do I need a passport to fly between San Antonio and Knoxville?

    No, a passport isn't needed to fly from San Antonio to Knoxville. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from San Antonio to Knoxville?

    San Antonio and Knoxville are both served by 1 main airport. You will leave San Antonio from San Antonio and will be arriving at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from San Antonio to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Antonio to Knoxville?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between San Antonio and Knoxville, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from San Antonio to Knoxville, Delta or Southwest?

    The two airlines most popular with KAYAK users for flights from San Antonio to Knoxville are Delta and Southwest. With an average price for the route of $341 and an overall rating of 7.9, Delta is the most popular choice. Southwest is also a great choice for the route, with an average price of $355 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from San Antonio to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Antonio to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Antonio to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from San Antonio is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Antonio to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to San Antonio with another airline. Booking your flights between San Antonio and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Antonio to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from San Antonio up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from San Antonio to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from San Antonio to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Antonio to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4265 reviews
7.0Food
8.0Comfort
8.6Crew
8.1Boarding
7.5Entertainment
Airline reviews

if I was good. Not happy that I have to pay extra money to get the seat I need for lake room, but I guess that’s a sign of the times.

8.0 ExcellentBobby, May 2026
MSY - BNA
Read more Southwest reviews

if I was good. Not happy that I have to pay extra money to get the seat I need for lake room, but I guess that’s a sign of the times.

First time I've had to use the disabled accommodations. And I could not have had a better experience with Southwest, i was having trouble getting from one terminal to another due to my heart failure. And the next thing I know a Southwest agent had made sure. I had a wheelchair at all my flights. Can't thank them enough.

The new seat assignment thing is wierd. If you don’t pay for a seat they always assign you a middle seat regardless of how many people are on the flight. Idk… the new company that bought Southwest is trying to make it more profitable, but I’m just not seeing it. The flight attendants aren’t having as much fun anymore. It just feels like the airline is slowly dying. IMO. We shall see if Southwest is the next Toy’s R Us.

The Air hostess were very rude on my flight from Houston to Austin . Their regular communication itself felt a they are shouting at people.

Plane was late. Zero service for 2+ hour flight and it was not that bumpy.

I have roller bag with food and medication told me I couldn't bring on my 2nd flight today. 15 years flying with SW never an issue with that bag.

Great flight. Good snacks and drinks. Grateful it was free. The flight from Nashville to louisville, i think her name was Tracy (not sure that's right) super awesome, nice and cheerful. She really enjoyed being at work today! She was the person who scanned the boarding pass on flight wn941. She should be recommended for a raise !

Southwest was greaat! The most expensive but the least upsetting for those we were flying to see.

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

I elected to pay for the upgrades and found very little difference

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

Clean planes and not take my comfort class seat away.

Weather caused a long delay, but the efficiency and updates from the pilot were helpful. We were able to make our connection fortunately.

Planes were clean, no water or snacks on either flight.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

MY FAMILY'S LUGGAGE WAS LOST FROM ROME TO BARI. I WAS THE ONLY ONE THAT RECEIVED MY LUGGAGE FROM ROME TO BARI. AFTER DEPLANING IN BARI, WE WASTED A LOT OF TIME AT BAG CLAIMS LOST AND FOUND REPORTING THE CLAIM AND PLEADING FOR THE BAGS TO BE DELIVERED THE NEXT DAY. WE WERE TOLD THAT IT TAKES 3 DAYS MINIMUM TO DELIVER. MY DAUGHTER AND MY GIRLFRIEND NEEDED THEIR PERSONAL THINGS AND WE WERE STAYING 3 HOURS AWAY FROM THE BARI AIRPORT. WE HAD TO DRIVE 3 HOURS TO THE AIRPORT TO COLLECT OUR LOST LUGGAGE THE NEXT DAY. WE ARE NOT HAPPY WITH THE EXPERIENCE

We had a delay, but thankfully I made it to my connection. Overall it went smooth

Left an hour and a half after the listed time. Up side was it had TV screens on the seat.

Great flight. Got to watch a movie. Smooth flight and early arrival at ORD.

Poor communication, flight was delayed for preventable reasons. I missed my connection.

Fine. The issues I had were associated with luggage being delayed from Turkey to Tanzania

I've been flying American mostly, and it's been very frustrating. This united flight makes me realize maybe the issue isn't flying, but the airline. United was a significantly better experience. The plane was more comfortable, with a normal amount of leg room (vs the ridiculous reductions AA has made), more comfortable seats, screens to watch movies. It was a much better experience!

We had excellent customer service despite the chaos at George Bush airport in Houston!

It isvvery small flight. No leg room . No space to put my personal item at feet.

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

They lost my baggage and I am still struggling to the information and update

Flight delays for communication overall not a good experience uncomfortable on the plane. Person in front of me reclined his seat, putting them inches from my lap.

Cancelled BOYH legs of our flight home 30 min before initial boarding

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

My flight got delayed a total of five times. And the boarding gate changed four times. most of the time the platform was not up-to-date with the changes taking place. The most discouraging part of the entire trip by far.

Returned home with a blood clot from flight homes and the uncomfortable aircraft I was on.

The crew was very kind, but no in-flight entertainment monitors and a 2 hour and 30 minute delay was extremely frustrating.

Everything you need to know for your flight from San Antonio to Knoxville

Information on your arrival and departure airports