SAT - TYS

$122 Find Cheap Flights from San Antonio to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Antonio to Knoxville departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Antonio to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Antonio to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$237
Overall average: $358
American Airlines
Thu 2/5Mon 2/9
SAT - TYS • 1 stop
Cheapest one-way
$101
Typical prices: $159-$420
Frontier
Thu 1/15
SAT - TYS • 1 stop
Top airlines
American Airlines
Cheapest • from $237 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 20% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
October
Cheapest • 27% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Antonio to Knoxville (SAT-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Antonio to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Antonio to Knoxville

Thu, Feb 5 - Mon, Feb 9
American Airlines Logo
6:41 am - 3:56 pm
SAT
-
TYS
8h 15m1 stop
American Airlines Logo
4:41 pm - 10:58 pm
TYS
-
SAT
7h 17m1 stop
$237American Airlines
Thu, Feb 5 - Sun, Feb 8
Delta Logo
5:20 am - 11:08 am
SAT
-
TYS
4h 48m1 stop
Delta Logo
11:58 am - 5:22 pm
TYS
-
SAT
6h 24m1 stop
$253Delta
Thu, Feb 5 - Sun, Feb 8
Multiple Airlines Logo
10:35 am - 6:28 pm
SAT
-
TYS
6h 53m1 stop
Multiple Airlines Logo
1:39 pm - 5:03 pm
TYS
-
SAT
28h 24m2 stops
$259Multiple Airlines
Mon, Feb 16 - Mon, Feb 23
American Airlines Logo
8:30 am - 5:16 pm
SAT
-
TYS
7h 46m1 stop
American Airlines Logo
5:40 am - 9:33 am
TYS
-
SAT
4h 53m1 stop
$268American Airlines
Fri, Feb 6 - Sun, Feb 8
American Airlines Logo
4:40 pm - 10:47 pm
SAT
-
TYS
5h 07m1 stop
American Airlines Logo
4:41 pm - 9:52 pm
TYS
-
SAT
6h 11m1 stop
$269American Airlines
Wed, Mar 11 - Sun, Mar 15
Southwest Logo
6:00 am - 11:50 am
SAT
-
TYS
4h 50m1 stop
Southwest Logo
1:35 pm - 12:30 am
TYS
-
SAT
11h 55m1 stop
$279Southwest
Wed, Mar 11 - Sun, Mar 15
Southwest Logo
11:10 am - 8:05 pm
SAT
-
TYS
7h 55m2 stops
Southwest Logo
1:35 pm - 12:30 am
TYS
-
SAT
11h 55m1 stop
$284Southwest
Sat, Jan 24 - Sun, Jan 25
United Airlines Logo
4:04 pm - 11:44 pm
SAT
-
TYS
6h 40m1 stop
United Airlines Logo
6:45 am - 12:24 pm
TYS
-
SAT
6h 39m1 stop
$295United Airlines
Fri, Feb 13 - Mon, Feb 16
Multiple Airlines Logo
10:26 am - 1:04 pm
SAT
-
TYS
25h 38m1 stop
Multiple Airlines Logo
9:36 pm - 9:30 am
TYS
-
SAT
12h 54m1 stop
$296Multiple Airlines
Sat, Jan 24 - Sun, Jan 25
United Airlines Logo
11:43 am - 8:52 pm
SAT
-
TYS
8h 09m2 stops
United Airlines Logo
6:59 am - 10:47 am
TYS
-
SAT
4h 48m1 stop
$304United Airlines
Booking Insights

KAYAK's insights & trends for San Antonio to Knoxville flights

Get data-powered insights and trends into flights from San Antonio to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Antonio to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Antonio to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Antonio to Knoxville is October, where tickets cost $254 (return) on average. On the other hand, the most expensive months are March and June, where the average cost of round-trip tickets is $488 and $378 respectively.

How far in advance should I book a flight from San Antonio to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Antonio to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Antonio to Knoxville, you should book around 5 weeks before departure, which saves you about 20% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$101
Best time to beat the crowds with an average 24% drop in price.
Most popular time to fly and prices are also 28% lower on average.
Flight from San Antonio to Knoxville

When to book flights from San Antonio to Knoxville

Are your dates flexible? Find out the best times to travel from San Antonio to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Antonio to Knoxville

  • What is the cheapest flight from San Antonio to Knoxville?

    In the last 3 days, the lowest price for a flight from San Antonio to Knoxville was $101 for a one-way ticket and $237 for a round-trip.

  • Do I need a passport to fly between San Antonio and Knoxville?

    No, a passport isn't needed to fly from San Antonio to Knoxville. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from San Antonio to Knoxville?

    San Antonio and Knoxville are both served by 1 main airport. You will leave San Antonio from San Antonio and will be arriving at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from San Antonio to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Antonio to Knoxville?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between San Antonio and Knoxville, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from San Antonio to Knoxville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from San Antonio to Knoxville are Delta and United Airlines. With an average price for the route of $328 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $358 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from San Antonio to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Antonio to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Antonio to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from San Antonio is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Antonio to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to San Antonio with another airline. Booking your flights between San Antonio and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Antonio to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from San Antonio up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from San Antonio to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from San Antonio to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Antonio to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8025 reviews
7.8Entertainment
7.2Food
8.1Boarding
8.5Crew
7.9Comfort
Airline reviews

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

2.0 MediocreWilliam, Jan 2026
LGA - BOS
Read more Delta reviews

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Flight was late from Newark to Atlanta, I asked flight attendant to please let my family of 3 out first when we landed to Atlanta because we were late for our connecting flight to Quito. She didn't and we were late for 5 minutes we couldn't board the plane and spend hours trying to get another flight with customer service for the next day.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Late delayed flight delays boarding and delays leaving and delays on arrival too. Cramped plane no room no food.

DTW line is too long. The flights from DTW to BWI are always delayed for unknown reasons.

Delta canceled our flight and we had to scramble to find another airline to get home. Phoenix is not a delta hub so they didn’t have another plane. It would have been a red eye though Salt Lake City. Getting in at 5am. No bueno.

This flight was no comparison to our prior flight. I'm thinking it all has to do with the age of the aircraft.

This flight was a first class choice and left much to be desired. Seat backs on seats were falling apart and torn. Seats actually didn't come to a "full & upright position". Pull out table was sprung. Not any significant leg room. All in all we were on an obviously older plane and felt overcharged for what we received as first class.

Flight was delayed several times. At one point, they "pulled back" 15 minutes from the delayed boarding and sent a text saying we would board sooner than previously advised. The flight then was delayed again. And when we boarded, there was an unspecified technical issue which had us waiting in the plane for about an hour.

Unbelievably poor service from flight attendants. They didn’t even do water service on a four hour flight. Just disrespectful.

Lately I like the planes have been exceptionally filthy. There’s lines of dust and dirt all across the ceiling in the vents, and the cracks in between the seats are literally full of food. It’s definitely not the quality of service that I was used to with United. I’m also very disappointed with the Wi-Fi! All I wanna do is knock out a few work jobs while I’m trapped in my seat And it spools so bad. They did provide me with a refund, but the process of getting that refund is so complicated. It’s unfortunate.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

Flight was good and crew was super polite. However, there were around 5 kids screaming the WHOLE 2 hours. I understand kids have to come but parents need to do something to control their children. They make the experience terrible, especially after finishing 16 hour shifts at the hospital I needed some sleep, which I did not get.

Once we got in the air the pilot made up some of the time of the delay. So that was really nice.

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

Overall it was good. I missed my connection but I was put on another flight.

Gate agent did not hold flight for connection, provided no assistance to get new flight

Smooth flight. Boarding was chaotic. Could not hear the gate agent over the intercom. People were lined up in the wrong lines. Groups one and two were told to board through line one and group 3 through line 2. All very confusing. Once in the air, the flight was smooth. There was no entertainment option on this aircraft, even though it was a larger aircraft.

We boarded but then sat there waiting on some missed connection people to get on so we sat for about 15 minutes for that. Then we sat again because the passenger manifest was wrong and they had to figure it out before we could leave. That took about another 20 minutes or so. The crew was working hard to figure it out so it’s not their fault. It ended up being a system glitch where someone was upgraded to first class while another person was also in the same seat and it just created a mess that took a little while to figure out. They literally went to every person on the plane asking their names to see who was sitting in the wrong seat. I also hate the entertainment that must be watched on your phone or tablet. Just give us setback screens. It’s so much better. Almost every Delta flight has this now and it is so nice to have them. The crew did a great job. I have no complaints from them. They were very hard working, even with the mishap and a disgruntled passenger.

We never made it due to delays on both ends. Gate attendant said it was mechanical but the system said otherwise, so no compensation. That’s not right.

The pilot greased the landing and the crew was fantastic.

delayed due to weather. Could not communicate with family since the wifi was broken

Attendants were pleasant and the flight was smooth and relaxed.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

Things were delayed a little. But that didn’t affect my plans. It was fine. I was surprised it was so full thanksgiving day. The crew were friendly and professional.

The flight was delayed multiple times, again no fault of American but again the extra cost, for everything makes it feel like a cheap airline! Especially when flights are outrageously expensive already

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

I have a gluten allergy so did have any food

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Everything you need to know for your flight from San Antonio to Knoxville

Information on your arrival and departure airports