TYS - SAN

$121 Find Cheap Flights from Knoxville to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to San Diego departing on 7/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to San Diego, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Knoxville to San Diego (TYS-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to San Diego

Mon, Jul 21 - Thu, Aug 7
 Logo
11:01 am - 11:06 pmTYS-SAN
15h 05m2 stops
 Logo
9:40 pm - 1:38 pmSAN-TYS
12h 58m1 stop
Mon, Aug 11 - Fri, Aug 15
 Logo
2:28 pm - 11:06 pmTYS-SAN
11h 38m1 stop
 Logo
7:01 pm - 10:04 amSAN-TYS
12h 03m2 stops
Tue, Jul 1 - Tue, Jul 22
American Airlines Logo
6:40 pm - 11:26 pmTYS-SAN
7h 46m1 stop
American Airlines Logo
2:27 pm - 11:52 pmSAN-TYS
6h 25m1 stop
$277American Airlines
Find Deal
Sat, Aug 9 - Sat, Aug 16
American Airlines Logo
5:06 am - 9:14 amTYS-SAN
7h 08m1 stop
American Airlines Logo
2:48 pm - 12:19 amSAN-TYS
6h 31m1 stop
$278American Airlines
Find Deal
Tue, Aug 26 - Sun, Aug 31
Delta Logo
1:00 pm - 6:01 pmTYS-SAN
8h 01m1 stop
Delta Logo
8:00 am - 5:19 pmSAN-TYS
6h 19m1 stop
$282Delta
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Fri, Jul 4 - Wed, Jul 9
Delta Logo
7:47 am - 1:55 pmTYS-SAN
9h 08m1 stop
Delta Logo
11:00 am - 8:05 pmSAN-TYS
6h 05m1 stop
$283Delta
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Tue, Jul 1 - Tue, Jul 22
United Airlines Logo
5:46 pm - 11:44 pmTYS-SAN
8h 58m2 stops
United Airlines Logo
9:50 pm - 10:27 amSAN-TYS
9h 37m1 stop
$372United Airlines
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Fri, Jul 4 - Thu, Jul 10
United Airlines Logo
7:00 am - 1:57 pmTYS-SAN
9h 57m2 stops
United Airlines Logo
10:41 am - 10:35 pmSAN-TYS
8h 54m1 stop
$378United Airlines
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Thu, Jul 3 - Sun, Jul 6
Frontier Logo
5:25 pm - 11:55 pmTYS-SAN
9h 30m1 stop
Frontier Logo
6:25 am - 4:29 pmSAN-TYS
7h 04m1 stop
$380Frontier
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Sun, Oct 5 - Fri, Oct 10
Frontier Logo
8:26 pm - 11:50 pmTYS-SAN
6h 24m1 stop
Frontier Logo
10:20 am - 7:37 pmSAN-TYS
6h 17m1 stop
$560Frontier
Find Deal
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KAYAK's insights & trends for Knoxville to San Diego flights

Get data-powered insights and trends into flights from Knoxville to San Diego to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Knoxville to San Diego?

The average price of all round-trip flights from Knoxville to San Diego clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Knoxville to San Diego, look for departures on Wednesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from San Diego, Wednesday is the cheapest day to fly and Sunday is the most expensive.

What is the cheapest month to fly from Knoxville to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to San Diego is January, where tickets cost $288 (return) on average. On the other hand, the most expensive months are April and May, where the average cost of round-trip tickets is $483 and $463 respectively.

How far in advance should I book a flight from Knoxville to San Diego?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Knoxville to San Diego, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Knoxville to San Diego, you should book around 3 weeks before departure. For the absolute cheapest price, our data suggests you should book 6 weeks before departure.

Good to know

Low seasonFebruary
High seasonAugust
Cheapest flight$121
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from Knoxville to San Diego

When to book flights from Knoxville to San Diego

Are your dates flexible? Find out the best times to travel from Knoxville to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to San Diego

  • What is the cheapest flight from Knoxville to San Diego?

    In the last 3 days, the lowest price for a flight from Knoxville to San Diego was $121 for a one-way ticket and $256 for a round-trip.

  • Do I need a passport to fly between Knoxville and San Diego?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Knoxville to San Diego?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to San Diego?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Knoxville and San Diego, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to San Diego, Delta or Alaska Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to San Diego are Delta and Alaska Airlines. With an average price for the route of $374 and an overall rating of 8.0, Delta is the most popular choice. Alaska Airlines is also a great choice for the route, with an average price of $503 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from Knoxville to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Knoxville to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 10000 reviews
7.1Food
7.1Entertainment
8.1Boarding
7.8Comfort
8.5Crew
Airline reviews

Horrible! No blanket or pillow available! We had bulkhead seats but the seats were worn out and no cushion old. No meal or even a sandwich for our 5 hour flight just a little bag of pretzels. Crabby attendant female with long brown hair. We will not book Alaska Airlines again

4.0 OkayAnonymous, Jun 2025KOA - SAN
Read more Alaska Airlines reviews

Horrible! No blanket or pillow available! We had bulkhead seats but the seats were worn out and no cushion old. No meal or even a sandwich for our 5 hour flight just a little bag of pretzels. Crabby attendant female with long brown hair. We will not book Alaska Airlines again

I do wish the the actual airplane I flew on was bigger. But, I made it work.

I loved that we boarded orderly and quickly, that I had an opportunity to check my bag free at the gate, that there was plenty of seat/leg room, there was smooth takeoff and landing, the attendants were pleasant and helpful, and that we arrived on time!!

We were in first class. Food was surprisingly good. Boarding was easy. Seats were lumpy. No video screen ...really? Service was good. Phone support was good

The staff and crew were excellent. The entire flight process was so friendly and smooth.

flight was canceled. don't cancel flights if you want a better score.

Missed connection due to waiting on tarmac for gate. Rebooking took 30 minutes in line with 2 people in line in front. Horrible inefficient careless staff.

The flight was canceled and very little help given at the check in desk. Everyone at the desk says: just go on the app and see how they rebooked you. I mean come on it’s embarrassing customer service.

The registration was chaotic. The kiosks didn't work for most people, and most had to do registration and receive boarding slips with a person. It took about an hour to get through he process, and I was worrying that I will be late to the flight. However, the personnel was great - courteous, professional, and was able to work through the problems.

I upgraded my seat and the service and boarding were wonderful. My flight attendant was very helpful when I experienced nausea on the flight (a first time experience). Flight arrived early which was nice. The only negative was many airlines have screens to provide some on flight entertainment, this aircraft did not. I had planned to read and listen to an audiobook on my flights, so no big deal on my part. The USB plug ins were broken on both my seat and the center seat, so I was not able to charge my phone during the flight, I will add 2 of the three USBs were broken on ride from San Diego as well. I would attribute this to the design, it is a very awkward angle to plug in, so frequent and perhaps not so gentle attempts to plug in have caused them to break.

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

The entertainment and wifi mostly didn't work on this flight.

Terrible entertainment system - kept freezing and audio kept cutting out. Snacks were mediocre at best for a 5 hour flight.

I am still upset that my bag was lost on a recent trip to Rome ; we were inconvenienced and out €150 Euros ; delta has refused to reimburse us

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Seats are much much more comfortable than United, which is what I usually fly

If I pay extra for "comfort+" I expect leg room where I can stretch my legs. I was seated with an attendant's seat blocking my feet. Knee space was fine but my feet had less room than the non-"comfort+" seats. Also, don't go cheap on food when you have flights of 3+ hours. It's insulting.

Only one side of the heafphone jack work. Crew was friendly and helpful.

Great. Flight departed early and arrived early. Deplaning and baggage claim ww were quick.

They separated our seats and moved us to the back of the plane. Hundreds of dollars and thousands of miles used and this was my platinum member experience.

Boarding was mayhem. Late boarding by 15 minutes because of lack of staff (missing 1 flight attendant. We had to wait for an arrival of another plane before we could board). Flight was a little rough, but cannot blame on airlines.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

United out of SFO is having issues with catering so none of our meals were loaded on the plane and no offer of compensation for our tickets purchased was offered.

A bit rush for transit. Food and entertainment are not available

The gate was too far away for the connecting flight

Generally good. The aisles have gotten narrower which can slow down boarding. Flight crew was great! Healthier complimentary snacks would be appreciated. Due to earthquake in San Francisco we had to circle in air space for a bit but then had a smooth landing. I laud the flight crew for their patience ;)

The agents was very rude and they charged me $50 for a carry-on bag saying that it was too big and then I saw someone going on a plane with the same size bag as me

For the most part united was a good experience, how ever when they came by with the snacks and water, they completely passed by my wife and I. As we were in separate rows. On a 5 hr flight we were not offered water

Fantastic crew. Flight was delayed at last minute but we were given updates every 20 minutes and the crew was so friendly and considerate. I miss the touch screens on the back of the seats, wish they would bring that back though.

Awful. Worst airline I have ever been on. Crew were among the rudest people I have ever dealt with. United staff members were rude and disrespectful. My flight was delayed, causing me to miss a connecting flight. I understand things happen, but when staff start lying about what actually happened, that is when I have an issue. Just be honest, really it isn’t that hard. I’m being very honest with this review and I don’t find this difficult what so ever. In fact, because of United Airlines, my Christmas holiday was off to a really rocky start. As someone who has traveled across the world, it has only been United that I have had a truly awful experience.

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

Long 5 hour and 45 min flight and only one drink service and cookie snack

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

I didn’t like anything, being platinum pro get you absolutely nowhere and does not increase the customer service treatment whatsoever anymore. My flight was canceled and they put me on a flight eight hours later that would’ve got me back in the middle of the night. They could’ve easily move me up to an hour Prior on an earlier flight. My second flight was unreasonable to take, the third flight was also canceled due to mechanical issues like the first flight. I don’t know what’s going on with American, but they are falling apart, after seven flight changes I finally got home, Unreasonable.

Bigger seats. Board back to front! Disembark front to back!

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

Plane was pretty clean, staff was friendly and helpful, flight left about on time arrived early. Took a long time to board and get off the plane - carry on items didn't have enough room so people had to move all around to find places.

Since you have to pay for overhead bags then they shouldn't be running out of space and asking individuals who paid to remove stuff from the overhead

Cancelled flight after I arrived at airport after 75 min drive and parking. Next flight was 4 days in the future. Had to scramble and buy a much more expensive flight on another carrier.

Book with frontier airlines with the mentality that they'll cancel your flight, kick you off and lose your luggage. Anything besides that is a win. Compare prices with other airlines (to include luggage) and if frontier is still worth it, book it but know all of their policies.

You get what you pay for nothing essentially but a hard uncomfortable seat that doesn’t recline and kids screaming all around you and chaotic boarding and limited check bag weight allowance when compared to other airlines

I never got to experience the flight because they delayed my first flight and I missed this one. Then Frontier didn't want to help me rebook a flight to get me to my final destination.

The Boarding process in Denver was chaotic, and since the line was so long, we were lined up very far from the gate. If there were any announcements from the gate staff, we didn't hear them. The flight attendants were spectacular. The only negative part of the flight was sitting by a 2 1/2 year old who was unruly and unfortunately had parents that matched his behaviors. Also, the restaurants in Denver on the E concourse, they didn't have food (passengers could only order 1 item on the entire menu) or the restaurants had 12-14 people waiting for orders to be prepared and another 6 people waiting to order. If you have a layover in Denver and need to grab food, be prepared to visit the shops with pre-packaged sandwiches, or you can visit another concourse but it may take a while to transit throughout the airport.

I liked the turn-style feature at gate 209B at LAX. Very efficient process. The gate staff also made several, clearly directed announcements so I felt very informed.

Although an hour and a half early was told by staff at check in they had overbooked and could not check us in for the flight.

The crew was delayed because they came on another flight that was delayed due to weather 10pm flight left at 1.30 am The airline made no effort to align alternate crew

Plane was down graded and I lost my uncharged exit row with more leg room. No mention or offer of refund from podium. Flight attendant was nice to explain this happens often and that I could request a refund via online form submission. I did this and have heard nothing back.

Everything you need to know for your flight from Knoxville to San Diego

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