Which airports can I use when flying from Knoxville to San Diego?

Flights from Knoxville to San Diego usually depart from Knoxville McGhee Tyson (TYS) and arrive at San Diego (SAN).

What cabin classes can I book on flights from Knoxville to San Diego?

Two cabin classes are available on flights from Knoxville to San Diego: • Economy Class • First Class

Which airports do connecting flights from Knoxville to San Diego pass through?

One-stop flights from Knoxville to San Diego most commonly connect through: • Atlanta Hartsfield-Jackson (ATL) - 31% of one-stop connections • Dallas/Fort Worth (DFW) - 31% of one-stop connections • Denver Intl (DEN) - 14% of one-stop connections • Houston George Bush Intcntl (IAH) - 7% of one-stop connections

Can I save money by using flexible dates for flights from Knoxville to San Diego?

Yes. Flexible dates can save you up to 23% on flights from Knoxville to San Diego. Saturday is the cheapest departure day at $397 round-trip on average, while Monday is the most expensive at $510, a difference of $113. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

What popular places can I visit in San Diego?

Some of the most popular sights in San Diego are Gaslamp Quarter, San Diego Convention Center and SeaWorld San Diego. These are among the most viewed places in San Diego on KAYAK.

How expensive are last-minute Knoxville to San Diego flights?

Last-minute fares on this route (booked within two weeks of departure) run 35% above the $434 route average. Book 24 weeks before departure for the lowest fares.

How long is a flight from Knoxville to San Diego?

A nonstop flight from Knoxville to San Diego takes 00m, covering 1,897 miles.

Do I need a passport to fly from Knoxville to San Diego?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

How are flight prices from Knoxville to San Diego looking right now?

One-way fares from Knoxville to San Diego are currently lower than usual. Average one-way flight prices are about $207, which is 24% below the typical average for this route.

How much time can I save by choosing a different layover airport from Knoxville to San Diego?

Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 6h 43m, compared with 7h via Dallas/Fort Worth (DFW) and 7h 01m via Atlanta Hartsfield-Jackson (ATL).

What is the time difference between Knoxville and San Diego?

San Diego is 3 hours behind Knoxville (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at San Diego Airport (SAN)?

San Diego Airport (SAN) hosts 5 major car rental companies, with daily rates averaging $53 for economy cars. Top options include: • Dollar • Payless • Europcar • Thrifty • Fox

How much should I expect to pay for a Knoxville to San Diego flight?

Round-trip flights from Knoxville to San Diego range from $360 to $537, with an average of $434 over the past 12 months. Anything below $360 counts as a good deal.

What's the cheapest day of the week to fly from Knoxville to San Diego?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Knoxville to San Diego. It’s 9% cheaper than the average day, while Monday is the most expensive, with prices 17% higher.

What’s the cheapest month to fly from Knoxville to San Diego?

•February is the cheapest month to fly from Knoxville to San Diego at $303 round-trip. •June ($563) and July ($516) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 85% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Knoxville to San Diego the cheapest?

Flights from Knoxville to San Diego are cheapest 24 weeks before departure. Booking in this window typically costs about 43% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Which airline is the cheapest to fly from Knoxville to San Diego?

American Airlines ($311) and Delta ($311) are the cheapest airlines to fly round-trip from Knoxville to San Diego according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Knoxville to San Diego?

Atlanta Hartsfield-Jackson (ATL) and Dallas/Fort Worth (DFW) are the most popular layovers for the Knoxville to San Diego route. 31% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ATL or DFW.

What is the cheapest layover airport when flying from Knoxville to San Diego?

Flights via Phoenix Sky Harbor Intl (PHX) offer the most affordable fares, with an average round-trip price of $274. Based on KAYAK data over the past 3 months.

When flying from Knoxville to San Diego which airport offers the shortest layover?

Dallas/Fort Worth (DFW) had the shortest average connection time for Knoxville to San Diego layovers at 4h 08m over the past 3 months.

$156 CHEAP FLIGHTS from Knoxville to San Diego (TYS - SAN)

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$247

Typical prices: $360-$537

Multiple Airlines

Thu 11/22Tue 12/4

TYS - SAN • 1 stop

Cheapest one-way

$156

Typical prices: $216-$380

Southwest

Sun 11/18

TYS - SAN • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Knoxville and San Diego. You'll need to take a connecting flight to reach the destination.

Insights

When to book

24 weeks

in advance

Our data shows that travelers who book at least 24 weeks in advance save around 43% compared to booking last minute.

Insights

When to travel

February

Cheapest • 30% price drop

May

Most popular

Good to know

Top layover airports

Phoenix Sky Harbor Intl (PHX)

Cheapest • Avg $274 (round-trip)

Nashville Intl (BNA)

Shortest trip • 6h 43m (one-way)

Insights

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to San Diego!

Flight Deals

Cheap Flights from Knoxville to San Diego (TYS-SAN)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Knoxville to San Diego

Sun, Nov 22 - Fri, Dec 4

6:20 am - 11:57 pmTYS Knoxville McGhee Tyson-SAN San Diego

20h 37m1 stop Denver Intl

9:05 am - 8:25 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 20m1 stop Las Vegas Harry Reid Intl

$247Multiple Airlines

Sun, Nov 22 - Thu, Dec 3

6:20 am - 11:57 pmTYS Knoxville McGhee Tyson-SAN San Diego

20h 37m1 stop Denver Intl

6:30 am - 1:43 pmSAN San Diego-TYS Knoxville McGhee Tyson

28h 13m2 stops Denver Intl Austin Bergstrom

$264Multiple Airlines

Sat, Dec 12 - Wed, Dec 16

2:55 pm - 9:12 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 17m1 stop Dallas/Fort Worth

1:11 pm - 12:35 amSAN San Diego-TYS Knoxville McGhee Tyson

8h 24m1 stop Dallas/Fort Worth

$311American Airlines

Thu, Dec 3 - Tue, Dec 8

6:50 am - 1:15 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 25m1 stop Charlotte Douglas

7:15 am - 4:39 pmSAN San Diego-TYS Knoxville McGhee Tyson

6h 24m1 stop Dallas/Fort Worth

$311American Airlines

Sat, Dec 12 - Tue, Dec 15

7:59 am - 12:12 pmTYS Knoxville McGhee Tyson-SAN San Diego

7h 13m1 stop Minneapolis St Paul

8:00 am - 8:14 pmSAN San Diego-TYS Knoxville McGhee Tyson

9h 14m1 stop Atlanta Hartsfield-Jackson

$311Delta

Sat, Dec 12 - Wed, Dec 16

5:40 am - 9:55 amTYS Knoxville McGhee Tyson-SAN San Diego

7h 15m1 stop Atlanta Hartsfield-Jackson

11:37 am - 9:33 pmSAN San Diego-TYS Knoxville McGhee Tyson

6h 56m1 stop Detroit Metropolitan Wayne County

$311Delta

Sat, Dec 12 - Wed, Dec 16

6:00 am - 11:27 amTYS Knoxville McGhee Tyson-SAN San Diego

8h 27m1 stop Chicago O'Hare Intl

12:35 pm - 11:59 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 24m1 stop Washington, D.C. Dulles Intl

$311United Airlines

Sat, Dec 12 - Wed, Dec 16

5:35 pm - 10:33 pmTYS Knoxville McGhee Tyson-SAN San Diego

7h 58m1 stop Chicago O'Hare Intl

8:40 am - 8:47 pmSAN San Diego-TYS Knoxville McGhee Tyson

9h 07m2 stops Denver Intl Chicago O'Hare Intl

$316United Airlines

Thu, Dec 3 - Tue, Dec 8

5:15 pm - 11:10 pmTYS Knoxville McGhee Tyson-SAN San Diego

8h 55m1 stop Nashville Intl

8:00 am - 7:50 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 50m2 stops Sacramento Intl Nashville Intl

$336Southwest

Thu, Dec 3 - Mon, Dec 7

7:05 am - 1:40 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 35m2 stops Nashville Intl Austin Bergstrom

6:35 am - 8:50 pmSAN San Diego-TYS Knoxville McGhee Tyson

11h 15m1 stop Baltimore/Washington

$342Southwest

Recent last minute flight deals from Knoxville to San Diego

Thu, Nov 5 - Thu, Nov 12

6:30 am - 11:57 pmTYS Knoxville McGhee Tyson-SAN San Diego

20h 27m1 stop Denver Intl

8:20 pm - 10:35 pmSAN San Diego-TYS Knoxville McGhee Tyson

23h 15m1 stop Las Vegas Harry Reid Intl

$452Multiple Airlines

Thu, Nov 5 - Thu, Nov 12

6:30 am - 11:57 pmTYS Knoxville McGhee Tyson-SAN San Diego

20h 27m1 stop Denver Intl

8:20 pm - 5:46 pmSAN San Diego-TYS Knoxville McGhee Tyson

18h 26m2 stops Las Vegas Harry Reid Intl Chicago O'Hare Intl

$475Multiple Airlines

Thu, Nov 5 - Thu, Nov 12

7:05 am - 12:10 pmTYS Knoxville McGhee Tyson-SAN San Diego

8h 05m2 stops Nashville Intl Dallas Love Field

6:45 am - 6:45 pmSAN San Diego-TYS Knoxville McGhee Tyson

9h 00m2 stops Phoenix Sky Harbor Intl Denver Intl

$599Southwest

Tue, Nov 3 - Sat, Nov 7

8:13 am - 1:08 pmTYS Knoxville McGhee Tyson-SAN San Diego

7h 55m1 stop Charlotte Douglas

12:28 pm - 9:39 pmSAN San Diego-TYS Knoxville McGhee Tyson

6h 11m1 stop Dallas/Fort Worth

$621American Airlines

Tue, Nov 3 - Sat, Nov 7

9:00 am - 12:56 pmTYS Knoxville McGhee Tyson-SAN San Diego

6h 56m1 stop Denver Intl

6:20 am - 6:00 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 40m2 stops Los Angeles Houston George Bush Intcntl

$626United Airlines

Tue, Nov 3 - Sat, Nov 7

1:56 pm - 6:34 pmTYS Knoxville McGhee Tyson-SAN San Diego

7h 38m1 stop Chicago O'Hare Intl

6:20 am - 6:00 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 40m2 stops Los Angeles Houston George Bush Intcntl

$626United Airlines

Tue, Nov 3 - Sat, Nov 7

7:05 am - 1:40 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 35m2 stops Nashville Intl Austin Bergstrom

5:45 pm - 3:00 pmSAN San Diego-TYS Knoxville McGhee Tyson

18h 15m2 stops Las Vegas Harry Reid Intl Dallas Love Field

$643Southwest

Tue, Nov 3 - Fri, Nov 6

8:13 am - 1:08 pmTYS Knoxville McGhee Tyson-SAN San Diego

7h 55m1 stop Charlotte Douglas

1:01 pm - 11:32 pmSAN San Diego-TYS Knoxville McGhee Tyson

7h 31m1 stop Dallas/Fort Worth

$761American Airlines

Tue, Nov 3 - Fri, Nov 6

5:30 am - 3:50 pmTYS Knoxville McGhee Tyson-SAN San Diego

13h 20m2 stops Dallas/Fort Worth Seattle/Tacoma Intl

8:07 pm - 6:35 pmSAN San Diego-TYS Knoxville McGhee Tyson

19h 28m2 stops Portland Dallas/Fort Worth

$771Alaska Airlines

Mon, Nov 2 - Fri, Nov 6

4:59 pm - 10:43 pmTYS Knoxville McGhee Tyson-SAN San Diego

8h 44m1 stop Chicago O'Hare Intl

8:07 pm - 6:35 pmSAN San Diego-TYS Knoxville McGhee Tyson

19h 28m2 stops Portland Dallas/Fort Worth

$786Alaska Airlines

Booking Insights

Price, demand and travel trends for Knoxville to San Diego flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

What's the cheapest day of the week to fly from Knoxville to San Diego?: Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Knoxville to San Diego. It’s 9% cheaper than the average day, while Monday is the most expensive, with prices 17% higher.
What’s the cheapest month to fly from Knoxville to San Diego? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Knoxville to San Diego, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •February is the cheapest month to fly from Knoxville to San Diego at $303 round-trip.
•June ($563) and July ($516) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 85% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.
When are flights from Knoxville to San Diego the cheapest?: Flights from Knoxville to San Diego are cheapest 24 weeks before departure. Booking in this window typically costs about 43% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Low season	September
High season	May
Cheapest flight	$156

Beat the crowds with an average 30% drop in travelers.

The most popular month to fly with an average 52% increase in travelers.

One-way flight from Knoxville to San Diego

When to book flights from Knoxville to San Diego

Are your dates flexible? Find out the best times to travel from Knoxville to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Knoxville to San Diego?
Two cabin classes are available on flights from Knoxville to San Diego:

• Economy Class
• First Class
How long is a flight from Knoxville to San Diego?
A nonstop flight from Knoxville to San Diego takes 00m, covering 1,897 miles.
Do I need a passport to fly from Knoxville to San Diego?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Knoxville to San Diego flight?
Round-trip flights from Knoxville to San Diego range from $360 to $537, with an average of $434 over the past 12 months. Anything below $360 counts as a good deal.
How expensive are last-minute Knoxville to San Diego flights?
Last-minute fares on this route (booked within two weeks of departure) run 35% above the $434 route average. Book 24 weeks before departure for the lowest fares.
How are flight prices from Knoxville to San Diego looking right now?
One-way fares from Knoxville to San Diego are currently lower than usual. Average one-way flight prices are about $207, which is 24% below the typical average for this route.
What car rental options are available at San Diego Airport (SAN)?
San Diego Airport (SAN) hosts 5 major car rental companies, with daily rates averaging $53 for economy cars. Top options include:

• Dollar
• Payless
• Europcar
• Thrifty
• Fox
Which airports can I use when flying from Knoxville to San Diego?
Flights from Knoxville to San Diego usually depart from Knoxville McGhee Tyson (TYS) and arrive at San Diego (SAN).
Which airports do connecting flights from Knoxville to San Diego pass through?
One-stop flights from Knoxville to San Diego most commonly connect through:

• Atlanta Hartsfield-Jackson (ATL) - 31% of one-stop connections
• Dallas/Fort Worth (DFW) - 31% of one-stop connections
• Denver Intl (DEN) - 14% of one-stop connections
• Houston George Bush Intcntl (IAH) - 7% of one-stop connections
Can I save money by using flexible dates for flights from Knoxville to San Diego?
Yes. Flexible dates can save you up to 23% on flights from Knoxville to San Diego. Saturday is the cheapest departure day at $397 round-trip on average, while Monday is the most expensive at $510, a difference of $113.

Cheaper weekend fares like these are typical of routes dominated by weekday business travel.
How much time can I save by choosing a different layover airport from Knoxville to San Diego?
Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 6h 43m, compared with 7h via Dallas/Fort Worth (DFW) and 7h 01m via Atlanta Hartsfield-Jackson (ATL).
What is the time difference between Knoxville and San Diego?
San Diego is 3 hours behind Knoxville (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.
What popular places can I visit in San Diego?
Some of the most popular sights in San Diego are Gaslamp Quarter, San Diego Convention Center and SeaWorld San Diego. These are among the most viewed places in San Diego on KAYAK.

If your dates are flexible, aim for a Saturday departure and avoid flying on Monday. On this route, Saturday flights average $397, about $113 less than Monday fares (22% savings) based on the last 12 months.
For the best chance at a low fare, aim to book around 24 weeks before you fly. On this route, that window historically saves about 43% versus last-minute pricing (KAYAK booking data, last 12 months).
If you can choose when to travel, plan your Knoxville to San Diego trip for February. Fares historically average $303 round-trip in that month - typically $260 less than the most expensive month, which is June (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to San Diego Airport.

• Courtyard by Marriott San Diego Downtown Little Italy
• Bay Club Hotel & Marina
• Sheraton San Diego Resort

More options for your flight from Knoxville to San Diego

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TYS - SAN

$156 Find Cheap Flights from Knoxville to San Diego - Compare and Save

Everything you should know

Cheap Flights from Knoxville to San Diego (TYS-SAN)

Recent round-trip flight deals from Knoxville to San Diego

Recent one-way flight deals from Knoxville to San Diego

Recent last minute flight deals from Knoxville to San Diego

Price, demand and travel trends for Knoxville to San Diego flights

What's the cheapest day of the week to fly from Knoxville to San Diego?

What’s the cheapest month to fly from Knoxville to San Diego?

When are flights from Knoxville to San Diego the cheapest?

Which airline is the cheapest to fly from Knoxville to San Diego?

What’s the most popular layover airport when flying from Knoxville to San Diego?

What is the cheapest layover airport when flying from Knoxville to San Diego?

When flying from Knoxville to San Diego which airport offers the shortest layover?

Key details for Knoxville to San Diego flights

Low season

High season

Cheapest flight

When to book flights from Knoxville to San Diego

Your Knoxville to San Diego flight questions, answered

Your guide to booking Knoxville to San Diego flights

More options for your flight from Knoxville to San Diego

Complete your trip to San Diego with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Knoxville to San Diego

Find direct flights to and from Knoxville and San Diego

Flights from domestic origins to San Diego

Flights to other popular destinations

Find deals for your return flight