TYS - SAN

$134 Find Cheap Flights from Knoxville to San Diego - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$267
Typical prices: $355-$539
Southwest
Wed 12/12Sun 12/16
TYS - SAN • 1 stop
Cheapest one-way
$134
Typical prices: $202-$379
Southwest
Sun 10/28
TYS - SAN • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Knoxville and San Diego. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
11 weeks
in advance
Our data shows that travelers who book at least 11 weeks in advance save around 44% compared to booking last minute.
Insights
Insights
When to travel
February
Cheapest • 29% price drop
May
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Phoenix Sky Harbor Intl (PHX)
Cheapest • Avg $274 (round-trip)
Nashville Intl (BNA)
Shortest trip • 6h 36m (one-way)
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Insights
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We hope you love your trip to San Diego!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to San Diego (TYS-SAN)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to San Diego

Mon, Oct 26 - Sat, Nov 14
Multiple Airlines Logo
9:42 pm - 10:11 amTYS  Knoxville McGhee Tyson-SAN San Diego
39h 29m2 stops Las Vegas Harry Reid Intl Phoenix Sky Harbor Intl
Multiple Airlines Logo
4:53 pm - 1:19 pmSAN  San Diego-TYS Knoxville McGhee Tyson
17h 26m1 stop Denver Intl
$273Multiple Airlines
Wed, Nov 11 - Wed, Nov 18
American Airlines Logo
7:30 pm - 11:56 pmTYS  Knoxville McGhee Tyson-SAN San Diego
7h 26m1 stop Dallas/Fort Worth
American Airlines Logo
2:18 pm - 11:32 pmSAN  San Diego-TYS Knoxville McGhee Tyson
6h 14m1 stop Dallas/Fort Worth
$299American Airlines
Fri, Dec 11 - Tue, Dec 15
American Airlines Logo
5:32 pm - 11:56 pmTYS  Knoxville McGhee Tyson-SAN San Diego
9h 24m1 stop Dallas/Fort Worth
American Airlines Logo
6:15 am - 4:42 pmSAN  San Diego-TYS Knoxville McGhee Tyson
7h 27m1 stop Dallas/Fort Worth
$303American Airlines
Fri, Oct 9 - Mon, Oct 12
Delta Logo
5:40 am - 9:42 amTYS  Knoxville McGhee Tyson-SAN San Diego
7h 02m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:00 pm - 10:20 amSAN  San Diego-TYS Knoxville McGhee Tyson
9h 20m1 stop Detroit Metropolitan Wayne County
$321Delta
Fri, Dec 11 - Tue, Dec 15
Southwest Logo
7:25 pm - 12:20 amTYS  Knoxville McGhee Tyson-SAN San Diego
7h 55m1 stop Nashville Intl
Southwest Logo
6:35 am - 7:45 pmSAN  San Diego-TYS Knoxville McGhee Tyson
10h 10m2 stops Denver Intl Nashville Intl
$331Southwest
Thu, Oct 15 - Tue, Oct 27
Multiple Airlines Logo
6:00 am - 2:29 pmTYS  Knoxville McGhee Tyson-SAN San Diego
11h 29m1 stop Phoenix Sky Harbor Intl
Multiple Airlines Logo
7:33 pm - 1:11 pmSAN  San Diego-TYS Knoxville McGhee Tyson
38h 38m2 stops Phoenix Sky Harbor Intl Denver Intl
$331Multiple Airlines
Fri, Dec 11 - Tue, Dec 15
Southwest Logo
3:40 pm - 10:15 pmTYS  Knoxville McGhee Tyson-SAN San Diego
9h 35m2 stops Dallas Love Field Denver Intl
Southwest Logo
6:30 am - 7:45 pmSAN  San Diego-TYS Knoxville McGhee Tyson
10h 15m2 stops Dallas Love Field Nashville Intl
$336Southwest
Sat, Dec 12 - Wed, Dec 16
Delta Logo
4:01 pm - 8:00 pmTYS  Knoxville McGhee Tyson-SAN San Diego
6h 59m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:00 am - 5:30 pmSAN  San Diego-TYS Knoxville McGhee Tyson
6h 30m1 stop Atlanta Hartsfield-Jackson
$337Delta
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
11:59 am - 5:53 pmTYS  Knoxville McGhee Tyson-SAN San Diego
8h 54m1 stop Houston George Bush Intcntl
United Airlines Logo
10:30 pm - 9:53 amSAN  San Diego-TYS Knoxville McGhee Tyson
8h 23m1 stop Chicago O'Hare Intl
$437United Airlines
Wed, Nov 11 - Wed, Nov 18
United Airlines Logo
6:45 am - 11:27 amTYS  Knoxville McGhee Tyson-SAN San Diego
7h 42m1 stop Chicago O'Hare Intl
United Airlines Logo
11:21 am - 11:59 pmSAN  San Diego-TYS Knoxville McGhee Tyson
9h 38m2 stops Denver Intl Washington, D.C. Dulles Intl
$442United Airlines
Booking Insights

Price, demand and travel trends for Knoxville to San Diego flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Knoxville to San Diego with more confidence.

How much is a round-trip flight from Knoxville to San Diego?

Round-trip flights from Knoxville to San Diego start at $267. Prices are below average for this route right now, with typical round-trip fares ranging from $355 to $539. The lowest price found in the past 5 days was $267 on Southwest.

What's the cheapest day of the week to fly from Knoxville to San Diego?

Saturday is the cheapest day of the week to fly from Knoxville to San Diego, it is 11% cheaper than the average day. Monday is the most expensive day with flight prices 10% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Knoxville to San Diego?

  • February is the cheapest month to fly from Knoxville to San Diego at $303 round-trip.
  • June ($551) and July ($516) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 81% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Knoxville to San Diego the cheapest?

Flights from Knoxville to San Diego are cheapest 11 weeks before departure. Booking in this window typically costs about 44% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Knoxville to San Diego flights

Low season

January

Cheapest flight

$134
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Knoxville to San Diego

When to book flights from Knoxville to San Diego

Are your dates flexible? Find out the best times to travel from Knoxville to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to San Diego flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Knoxville to San Diego?

    Flights from Knoxville to San Diego usually depart from Knoxville McGhee Tyson (TYS) and arrive at San Diego (SAN).

  • What cabin classes can I book on flights from Knoxville to San Diego?

    Three cabin classes are available on flights from Knoxville to San Diego:

    • Economy Class
    • Premium Economy Class
    • First Class

  • Which airports do connecting flights from Knoxville to San Diego pass through?

    One-stop flights from Knoxville to San Diego most commonly connect through:

    • Dallas/Fort Worth (DFW) - 34% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 29% of one-stop connections
    • Denver Intl (DEN) - 16% of one-stop connections
    • Charlotte Douglas (CLT) - 5% of one-stop connections

    Dallas/Fort Worth (DFW) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Knoxville to San Diego?

    On the Knoxville to San Diego route, being flexible with your departure day can save you up to 20%. Saturday is the cheapest day at $384 round-trip on average, while Monday is the most expensive at $476: a $92 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • What popular places can I visit in San Diego?

    Some of the most popular sights in San Diego are Gaslamp Quarter, San Diego Convention Center and SeaWorld San Diego. These are among the most viewed places in San Diego on KAYAK.

  • How expensive are last-minute Knoxville to San Diego flights?

    Last-minute fares on this route - booked within 2 weeks of departure - run 32% above the route average of $429. Book 11 weeks before departure for the lowest fares.

  • How long is a flight from Knoxville to San Diego?

    A nonstop flight from Knoxville to San Diego takes 0h 00m, covering 1,897 miles.

  • Do I need a passport to fly from Knoxville to San Diego?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Knoxville to San Diego changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $267 to $2,146. That means the highest observed fare was about 8x higher than the lowest one.

  • How are flight prices from Knoxville to San Diego looking right now?

    One-way fares from Knoxville to San Diego are currently lower than usual. Average one-way flight prices are about $209, which is 22% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Knoxville to San Diego?

    Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 6h 36m, compared with 6h 59m via Dallas/Fort Worth (DFW) and 7h 00m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between Knoxville and San Diego?

    San Diego is 3 hours behind Knoxville (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at San Diego Airport (SAN)?

    San Diego Airport (SAN) hosts 5 major car rental companies, with daily rates starting from around $14 for economy cars. Top options include:
    • Dollar
    • Payless
    • Europcar
    • Thrifty
    • Fox

  • How much should I expect to pay for a Knoxville to San Diego flight?

    Round-trip flights from Knoxville to San Diego range from $355 to $539, with an average of $429 over the past 12 months. Anything below $355 counts as a good deal.

Your guide to booking Knoxville to San Diego flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Saturday departure instead of Monday. On this route, Saturday flights average $384 - about $92 less than Monday (19% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 11 weeks before you fly. On this route, that window historically saves about 44% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Knoxville to San Diego trip for February. Fares historically average $303 round-trip in that month - typically $248 less than the most expensive month, which is June (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Diego Airport.
    - Courtyard by Marriott San Diego Downtown Little Italy
    - Bay Club Hotel & Marina
    - Sheraton San Diego Resort

More options for your flight from Knoxville to San Diego

Complete your trip to San Diego with a hotel stay or car rental

Car rentals in San Diego
Hotels in San Diego
Vacations in San Diego