TYS - SAN

$117 Find Cheap Flights from Knoxville to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to San Diego departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to San Diego, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$232
Typical prices: $544-$355
Frontier
Mon 6/1Wed 6/10
TYS - SAN • 1 stop
Cheapest one-way
$116
Typical prices: $153-$277
Frontier
Wed 7/22
TYS - SAN • 1 stop
Top airlines
Cheapest • from $232 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and San Diego. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $334 (round-trip)
Shortest trip • 6h 30m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 25% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 30% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Diego!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to San Diego (TYS-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to San Diego

Mon, Jun 1 - Wed, Jun 10
Frontier Logo
8:32 pm - 8:42 am
TYS
-
SAN
15h 10m
1 stop
Frontier Logo
6:25 am - 7:37 pm
SAN
-
TYS
10h 12m
1 stop
$232Frontier
Mon, Jun 1 - Wed, Jun 10
Multiple Airlines Logo
6:00 am - 11:50 pm
TYS
-
SAN
20h 50m
2 stops
Multiple Airlines Logo
6:25 am - 7:37 pm
SAN
-
TYS
10h 12m
1 stop
$270Multiple Airlines
Mon, Jun 1 - Mon, Jun 8
Frontier Logo
8:32 pm - 8:42 am
TYS
-
SAN
15h 10m
1 stop
Frontier Logo
6:25 am - 7:33 pm
SAN
-
TYS
10h 08m
1 stop
$280Frontier
Mon, Jun 22 - Fri, Jun 26
Frontier Logo
8:32 pm - 9:09 am
TYS
-
SAN
15h 37m
1 stop
Frontier Logo
10:04 am - 7:37 pm
SAN
-
TYS
6h 33m
1 stop
$281Frontier
Mon, Jun 1 - Wed, Jun 10
Multiple Airlines Logo
8:32 pm - 8:42 am
TYS
-
SAN
15h 10m
1 stop
Multiple Airlines Logo
9:43 am - 11:59 am
SAN
-
TYS
47h 16m
2 stops
$309Multiple Airlines
Thu, Jun 4 - Thu, Jun 11
Multiple Airlines Logo
7:00 am - 11:50 pm
TYS
-
SAN
19h 50m
1 stop
Multiple Airlines Logo
9:43 am - 4:40 pm
SAN
-
TYS
27h 57m
2 stops
$319Multiple Airlines
Wed, Jun 24 - Mon, Jun 29
Frontier Logo
8:32 pm - 9:09 am
TYS
-
SAN
15h 37m
1 stop
Frontier Logo
6:25 am - 7:37 pm
SAN
-
TYS
10h 12m
1 stop
$325Frontier
Sun, May 31 - Thu, Jun 4
Multiple Airlines Logo
7:00 am - 8:42 am
TYS
-
SAN
28h 42m
1 stop
Multiple Airlines Logo
9:43 am - 4:40 pm
SAN
-
TYS
27h 57m
2 stops
$329Multiple Airlines
Mon, Jun 1 - Wed, Jun 10
Frontier Logo
8:32 pm - 11:50 pm
TYS
-
SAN
30h 18m
1 stop
Frontier Logo
6:25 am - 7:37 pm
SAN
-
TYS
10h 12m
1 stop
$333Frontier
Wed, Jun 10 - Mon, Jun 15
Frontier Logo
8:32 pm - 9:09 am
TYS
-
SAN
15h 37m
1 stop
Frontier Logo
4:17 pm - 7:37 pm
SAN
-
TYS
48h 20m
2 stops
$334Frontier
Booking Insights

KAYAK's insights & trends for Knoxville to San Diego flights

Get data-powered insights and trends into flights from Knoxville to San Diego to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to San Diego?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to San Diego departing in June.

What is the cheapest month to fly from Knoxville to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to San Diego is July, where tickets cost $288 (return) on average. On the other hand, the most expensive months are March and November, where the average cost of round-trip tickets is $512 and $467 respectively.

How far in advance should I book a flight from Knoxville to San Diego?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Knoxville to San Diego, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Knoxville to San Diego, you should book around 4 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low seasonDecember
Cheapest flight$117
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Knoxville to San Diego

When to book flights from Knoxville to San Diego

Are your dates flexible? Find out the best times to travel from Knoxville to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to San Diego

  • What is the cheapest flight from Knoxville to San Diego?

    In the last 3 days, the lowest price for a flight from Knoxville to San Diego was $116 for a one-way ticket and $232 for a round-trip.

  • Do I need a passport to fly between Knoxville and San Diego?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Knoxville to San Diego?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to San Diego?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Knoxville and San Diego, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to San Diego, Delta or Alaska Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to San Diego are Delta and Alaska Airlines. With an average price for the route of $382 and an overall rating of 7.9, Delta is the most popular choice. Alaska Airlines is also a great choice for the route, with an average price of $436 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Knoxville to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Knoxville to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
Alaska AirlinesOverall score based on 12329 reviews
7.0Entertainment
8.5Crew
7.8Comfort
8.1Boarding
7.1Food
Airline reviews

The seat on the plane out was broken and would not lean back. I have back problems and sitting up straight was hard on my lower back and caused pain for over half the flight. Since I paid extra for First Class so I would not have these issues. This needs to be addressed.

6.0 GoodTerence, Apr 2026
TPA - SAN
Read more Alaska Airlines reviews

The seat on the plane out was broken and would not lean back. I have back problems and sitting up straight was hard on my lower back and caused pain for over half the flight. Since I paid extra for First Class so I would not have these issues. This needs to be addressed.

No headphones provided. No gf food. Only 1 beverage cart run sAN to HNL. Rarely saw crew members

A solidly good experience, but would’ve appreciated more communication with regards to travel delays.

No issues and clear sailing. What a preferred to have sat in one of empty seats other than my assigned seat that would be my only complaint if it was to complain.

Perpetually delayed, flight out was delayed almost 2 hours, flight home was delayed an hour and a half. On the way back no refreshments as an option, yet they gave it out to 1st class. No apology or notice of the delay going out both ways. Seats are nice feature wise, but the adjustable headrests don't stay up anymore. Feels more like a budget airline

Four hour delay. Missed our event. And they offered me $75. Absolutely shameful.

I have been flying commercial for decades. I was in one of the ladder boarding groups, had my bag tagged because they thought there was not going to be enough space for it in the overhead bins. I politely asked one of the attendance if I could try to find a space- she said I could and I did. I then took the bag tag off and gave it to one of the other attendants as I was told to do by the first one. He, in a curt, anal, and disrespectful manner, told me that I needed to take my bag down from the overhead bin and check it. This was a situation I’ve never encountered before. The attendant’s attitude was confrontational and belittling in front of other onlooking passengers as if daring me to challenge him. I am a physician who takes care of patients day in and day out. Not wanting to make a scene, I calmly told him, “do what you need to do.” he took my bag down from the overhead bin, put the back tag back on it, and checked it only to make room for another bag that was also supposed to be technically checked by a following passenger. The same male attendant later came up to me and said “you shouldn’t have showed me the bag tag,” as if conveying that he was just following protocol was a justification for treating me like a kid out of line. I cared about this because it took 15 minutes from my life to then retrieve the bag at baggage claim and it also felt like really poor customer service. I understand the need for protocols. This is also a service industry, and we the passengers are the clients. We should be made to feel welcome and respected and our life in transit made as easy as it can be within reason. This attendant clearly needs to be reminded of that. Of note, an older female fellow passenger sitting next to me agreed with this assessment.

The boarding process could be clearer, there's never a call for group f

good, no complaints but nothing to rave about. It was fine

I love Alaska! We arrived on the later side without seat assignments only to find the had oversold the flight by 1. The attendants worked extra hard to find a way for our party of 7 to stay together and we made it on the flight! Loved the free WiFi also!

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

WiFi didn’t work most of the time. The usb chargers would work only occasionally for 5 mins and wouldn’t charge after that. Had to keep trying repeatedly at each of the seats in the row.

The crew bent over backwards to thank us for flying and make us comfortable. The food service was quick and efficient. The Captain communicated and said goodbye and thank you as we departed. They really stood out!

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

Staff at the check-in counter were friendly, happy and helpful. They tagged our bags and sent us to “bag drop off” but were not very clear about where that was. The airport was busy we headed off in what we thought was the right direction until a gentleman waved us down and actually came after us. He was the baggage handler for Delta and recognized our “deer in the headlights “ look-he brought us to the right area (which was marked as the Southwest Airlines Drop Off) and sent us on our way. Wonderful guy, low key and working with a big smile on his face. Loved it. Loved him.

Arlene was a great flight attendant. I also liked how one of the other flight attendants gave us a heads up about snacks and asked everyone to remove their headphones when it was their turn to order. Good idea.

I haven’t flown economy in over 20 years but it was not bad. Room by my feet for my bag and seat was roomy enough. Surprised in a good way.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

The flight was delayed from take off because only one runway was operational in San Francisco.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Packed in plane small uncomfortable seats elbow to elbow nobody wants to be in that situation for the money they paid

Checking in united could not figure out my star alliance gold. Baggage did not get marked priority and didn't receive boarding passes. When got to SFO lounge personal fixed everything Immediately

Flight left on time, arrived early, pleasant staff provided water, coffee, etc. access to bathrooms was reasonable and were well maintained. blankets were available, lots of entertainment options. LUGGAGE SERVICE WAS GREAT. I got my one checked bag quickly and was able to make a bus connection for a 2 hour bus ride saving me from waiting another 1.5 hours.

Terrible, if possible won't be flying again anytime soon!

Wonderful in-seat entertainment with seatback screens and huge selection of quality movies. The ability to bluetooth connect headphones was amazing.

Horrible service no Wi-Fi connection on both leg of the flight and they are refusing to fix bad service

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

To have arrived on time and not 3 hours late after having already spent $100 to change to an earlier flight, only to arrive back home close to the original flight time.

American Airlines is a miserable experience. It is predictably miserable, in the sense that every time I fly American, I brace myself for the certainty that it will be unpleasant and uncomfortable. But it is unpredictable in the sense that I never know if the flight will be on time or delayed nine hours (both happened to me this week). I never know if I will be able to sit in the seat that I selected when I purchased the ticket or if I will be told by Customer Service (!!!) that I must relocate from first class to a seat in the back of the aircraft with no explanation (both happened to me this week). Will the food be frozen and half defrosted, or scalding hot? Will the drinks be warm? Will the flight attendants be surly and mean? Will the toilets be cramped and foul? Will the seats be narrow and uncomfortable? Will there be a real electric outlet at the seat, or just an unreliable USB-2 port? Will there be enough seats in the boarding lounge or just a few? Will the boarding process be smooth and efficient, or will the gate agents mess it up and delay it needlessly for 30 or 40 minutes? Will the catering and cleaning crew be prompt or will they take an extra 30 minutes? Will the brakes on the aircraft work properly, or will the pilot delay takeoff for four hours while the ground crew attends to what can only be described as routine maintenance that should have been done the night before? I've eexperienced every one of these unpleasant things this year, 2026. The only thing I can reliably count on is that American will find a new way to make the experience of flying as miserable as they possibly can.

Wifi was spotty. Tray table was very dirty when I sat down.

The WiFi would not connect enough for me to do my actual work. It permaspooled, disconnected, said it was connected, then wouldn't open an email... it was frustrating. I am not a tall person, 5'4" - and I felt cramped with little room to reach into my bag under the seat in front of me. I feel sorry for anyone taller than me having to fly. the one positive thing I will add, is the overhead bins are roomy enough to manage more bags than other carriers.

Going non stop to lax like I paid for. Not stopping in MCI for gas. Too long of delays

Delayed for mechanical and no updates on what was happening and how long the delay might be.

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

The experience at checkin for my American Airlines flight from Sacramento to LAX was very good including the assistance I received in getting my bags checked in and boarding passes printed. Was pleasantly surprised the my bags were checked through all the way to my destination at Clark International Airport in Angeles, Philippines.

Frontier scheduled a 40 minute connection in DEN. What they failed to mention was that they “close the doors” 20 mins prior to departure, which means you only have 20 mins. Not enough time. Possibly against DOT regulations. Filing complaint.

Flight was scheduled at 9:40pm. Got delayed to 10 am, the next day. crazy

The bag check, flight check-in, and onboard experience convinced my wife and me that we will actively go out of our way to avoid flying Frontier Airlines in the future. At bag check, we were informed that check-in could only be completed via the Frontier mobile app. Unfortunately, the app was extremely frustrating—sending us through repetitive, confusing loops that repeatedly forced us to decline add-on services with nearly every click. While most airline apps upsell, this one felt intentionally exhausting. As the process dragged on, we became genuinely concerned that my phone battery would die before check-in could be completed. We approached the bag check staff—who were standing together talking—and explained both our frustration and our predicament. They laughed. Later, my wife described the interaction as “gaslighting,” which felt accurate. We were then informed it would cost $25 per person simply to have our boarding passes printed. From that point forward, the tone of the experience was consistently hostile. The bag check employees were condescending and combative, behaving more like bullies than customer service staff. Unfortunately, that same attitude continued onboard. One flight attendant argued with me when I attempted to stow my backpack in the overhead bin. I explained that we had each paid $75 to check our bags specifically so we would not need to use carry-on space and could have adequate legroom. She demanded to see my ticket, pointed out that it said “no carry-on”—which I acknowledged—and I reiterated that this was precisely why we paid to check our bags. Her response was, “I don’t make the rules.” She then walked away, but not before asking if I “truly wanted to fly back to Chicago today?”—an unnecessary and unmistakable threat. It is also worth noting that despite booking our tickets together in the same transaction, we were not seated together. Upon our return to Chicago—where we could once again sit together—we compared onboard experiences. We both remarked on how unhappy the flight attendants appeared and how each of us was separately asked whether we would like to purchase a beverage. We declined. At no point was water mentioned as an option, leaving us with the clear impression that even water came at a cost—or that complimentary water, if available at all, was deliberately left unmentioned. Overall, the experience was shocking and deeply disappointing, but it was also a profound learning experience—one we will not forget and will not repeat. -Steve

Plane was hot and miserable and the crew was rude!

12 hour delay required getting on and off plane 3 times - would have at least liked to have been offered a snack or drink

They didn’t offer a water, even after I asked

They switched our terminal 3 times and we were delayed for four plus hours!!!

It was an early flight and most people napped/slept and the crew let us which was nice.

The crew acted like they had never done this and kept barking passive aggressive orders at people. + the security line + the delay + sitting on the tarmac for 2 hours + none of the apps or signage updating with correct times

More inflight connection. And leg space is horrible. And the paying for baggage I'd ridiculous!!!

Everything you need to know for your flight from Knoxville to San Diego

Information on your arrival and departure airports