SAN - TYS

$127 Find Cheap Flights from San Diego to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Diego to Knoxville departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to Knoxville, as well as popular online travel agencies
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Flights Deals

Cheap Flight Deals from San Diego to Knoxville (SAN-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Diego to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from San Diego to Knoxville

KAYAK's recommended round-trip deals from the most popular airlines that fly from San Diego to Knoxville.
Discover the best prices for you by selecting your travel dates on KAYAK.
Frontier Logo
6:41 am - 4:35 pmSAN-TYS
6h 54m1 stop
Frontier Logo
5:25 pm - 11:55 pmTYS-SAN
9h 30m1 stop
$238Frontier
Find Deal
Thu, May 29 - Thu, Jun 5
 Logo
6:58 pm - 9:28 pmSAN-TYS
23h 30m2 stops
 Logo
9:34 pm - 7:53 pmTYS-SAN
25h 19m2 stops
Thu, May 29 - Thu, Jun 5
United Airlines Logo
12:35 pm - 10:28 pmSAN-TYS
6h 53m1 stop
United Airlines Logo
7:00 am - 11:23 amTYS-SAN
7h 23m1 stop
$277United Airlines
Find Deal
Tue, Jun 3 - Sat, Jun 7
United Airlines Logo
11:31 am - 11:59 pmSAN-TYS
9h 28m2 stops
United Airlines Logo
7:00 am - 11:23 amTYS-SAN
7h 23m1 stop
$282United Airlines
Find Deal
Tue, Jun 3 - Sat, Jun 7
American Airlines Logo
8:10 am - 7:56 pmSAN-TYS
8h 46m1 stop
American Airlines Logo
9:05 am - 1:38 pmTYS-SAN
7h 33m1 stop
$283American Airlines
Find Deal
Wed, May 21 - Sat, May 31
Delta Logo
11:00 am - 8:05 pmSAN-TYS
6h 05m1 stop
Delta Logo
5:12 pm - 10:38 pmTYS-SAN
8h 26m1 stop
$289Delta
Find Deal
Thu, Jul 17 - Mon, Jul 21
Delta Logo
6:20 am - 6:17 pmSAN-TYS
8h 57m1 stop
Delta Logo
6:05 pm - 11:13 pmTYS-SAN
8h 08m1 stop
$308Delta
Find Deal
Thu, Aug 28 - Tue, Sep 2
American Airlines Logo
2:27 pm - 11:58 pmSAN-TYS
6h 31m1 stop
American Airlines Logo
6:25 pm - 11:56 pmTYS-SAN
8h 31m1 stop
$329American Airlines
Find Deal
Tue, Jun 3 - Sat, Jun 7
Alaska Airlines Logo
3:45 pm - 11:41 amSAN-TYS
16h 56m2 stops
Alaska Airlines Logo
2:56 pm - 8:46 pmTYS-SAN
8h 50m1 stop
$494Alaska Airlines
Find Deal
Fri, May 16 - Mon, May 19
Alaska Airlines Logo
7:15 am - 10:18 amSAN-TYS
24h 03m2 stops
Alaska Airlines Logo
4:35 pm - 9:47 pmTYS-SAN
8h 12m1 stop
$514Alaska Airlines
Find Deal
Thu, Sep 11 - Sun, Sep 14
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KAYAK's insights & trends for San Diego to Knoxville flights

Get data-powered insights and trends into flights from San Diego to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from San Diego to Knoxville?

The average price of all round-trip flights from San Diego to Knoxville clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Knoxville on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from San Diego to Knoxville. For your return ticket, we recommend flying on a Wednesday and avoiding Sundays for the best deals.

What is the cheapest month to fly from San Diego to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Diego to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Diego to Knoxville is January, where tickets cost $316 (return) on average. On the other hand, the most expensive months are December and March, where the average cost of round-trip tickets is $548 and $503 respectively.

How far in advance should I book a flight from San Diego to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Diego to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Diego to Knoxville, you should book around 3 weeks before departure. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low seasonJanuary
High seasonDecember
Cheapest flight$127
Best time to beat the crowds with an average 26% drop in price.
Most popular time to fly with an average 28% increase in price.
Flight from San Diego to Knoxville

When to book flights from San Diego to Knoxville

Are your dates flexible? Find out the best times to travel from San Diego to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Diego to Knoxville

  • What is the cheapest flight from San Diego to Knoxville?

    In the last 3 days, the lowest price for a flight from San Diego to Knoxville was $127 for a one-way ticket and $238 for a round-trip.

  • Do I need a passport to fly between San Diego and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from San Diego to Knoxville?

    On your way to Knoxville, you’ll fly out from San Diego. You’ll be landing at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from San Diego to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Diego to Knoxville?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between San Diego and Knoxville, with oneworld being the most commonly used for this route.

  • What is the most popular layover when flying to Knoxville from San Diego?

    Dallas is the most popular layover city among KAYAK users traveling from San Diego to Knoxville.

  • Which is the best airline for flights from San Diego to Knoxville, Delta or Alaska Airlines?

    The two airlines most popular with KAYAK users for flights from San Diego to Knoxville are Delta and Alaska Airlines. With an average price for the route of $392 and an overall rating of 8.0, Delta is the most popular choice. Alaska Airlines is also a great choice for the route, with an average price of $798 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from San Diego to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Diego to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Diego to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from San Diego is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Diego to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to San Diego with another airline. Booking your flights between San Diego and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Diego to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from San Diego up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top 5 airlines serving from San Diego to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from San Diego to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Diego to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 9968 reviews
7.9Comfort
8.2Boarding
7.1Entertainment
7.1Food
8.5Crew
Airline reviews

My youngest didn't have a assigned seat until we biard6the plane.

2.0 MediocreStephanie, Apr 2025SAN - SLC
Read more Alaska Airlines reviews

My youngest didn't have a assigned seat until we biard6the plane.

There was no seating at the gate, no where to charge your devices, super crowded. Boarding in group F meant all luggage space was taken when it was time for me to board. The boarding crew was short with everyone and seemed irritated. The luggage space was insufficient, the seat was too small for me (6'4") and very uncomfortable trip. I was in a middle seat between a person snoring the whole trip and a person with very strong body odor. The flight crew was terse and unfriendly, seemed irritated and impatient. Yelled a lot at people with earbuds in, understandable. Finally, we arrived 10 minutes early, only to sit on the tarmac for 20 minutes and wait for a gate. Worst flight experience I've had in years.

The flight was delayed by 3 hours and 30 minutes without any explanation.

A little delay but nice flight, nice team. Thank you.

They lock the bathrooms too soon before landing! My bladder was bursting for over an hour. Then the plane had to sit on the taxiway for 1 hour. People started rushing to the bathroom. Creating a dangerous situation.

flight was late resulting in us missing our prepaid hotel shuttle

Only problem my credit card had over three pending credit card charges for luggages. I hope these charges do not post. I have already contacted my credit card companies.

Flight was late to board, then overweight. I booked a non stop flight for a reason, ended up having to re-fuel in Texas, arrived three hours late.

My seat was comfortable. There was no TV on the airplane.

Everything was good. Uneventful flight, which is the best kind.

Delta flight was on time, seats were comfortable, and crew was nice.

Thank you for not flipping the plane on the run way. You guys get a 5 star rating for the flight!!!

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

Kind staff. Snacks are small but that’s the new normal.

It was terrible, if they ran flights on time it would make a big difference.

Delta seems to be improving in many areas, except they are super bad with the food available. Bring back normal food service on long flights.

I actually received a notification from kayak on email but not one by text from Delta when my departure gait changed and I almost missed my flight

New boarding doesn't make sense. Filling front first is slow.

Delta flight was great from the check in all the way to arrival. However, I had a very bad experience. I requested a wheelchair and the wheelchair employee that went to pick me up from the plane in Boston to bring me to the baggage claims told me I have to pay him. I was under the impression that it was a free service and I usually give tips but the person forced me to pay and since I said no because I was upset with his demand when my daughter walked in to pick me up he demanded payment from my daughter who paid him thinking maybe now it is a charged service.

Horrible. Grateful to be alive but spent 13 hours at airport only to return back to my familys house and flight changed to next day. They tried to fix a part on plane, had no back up plane and after 10 hours , reattempted the flight and it STILL wasn't fixed. We got a meal voucher and rescheduled flight but there should be some other compensation for the 15 hours spent in airport

The gate was too far away for the connecting flight

Compared with other carriers business class for an overnight was not worth the extra expense.

Easy to board. Flight was super crowded though so I didn't sleep well on that cross country red-eye flight. The aisles seem ot have gotten narrower and the seat smaller whn luggage and people are getting bigger so it would be AWESOME to have more space and breathing room in general ;)

We boarded but then sat there waiting on some missed connection people to get on so we sat for about 15 minutes for that. Then we sat again because the passenger manifest was wrong and they had to figure it out before we could leave. That took about another 20 minutes or so. The crew was working hard to figure it out so it’s not their fault. It ended up being a system glitch where someone was upgraded to first class while another person was also in the same seat and it just created a mess that took a little while to figure out. They literally went to every person on the plane asking their names to see who was sitting in the wrong seat. I also hate the entertainment that must be watched on your phone or tablet. Just give us setback screens. It’s so much better. Almost every Delta flight has this now and it is so nice to have them. The crew did a great job. I have no complaints from them. They were very hard working, even with the mishap and a disgruntled passenger.

Had a short delay once we boarded the aircraft in Chicago, but it was fixed in no time flat then we were on our way. The pilot was able to make up the time lost and we landed 5 minute later then schedualed . Great service

Pilot Erika DeLong made us feel safe and at ease in a frankly scary time to be flying. Her warm smile and greeting and excellent command of the aircraft in foggy bumpy weather helped us all to calm our nerves and get us home safely.

Plenty of room for me and the cat in Premium Economy. Seat was comfortable. Boarding was a breeze. The lady at the special check-in desk was great, super helpful and professional.

Wish movie and music choices changed more often. Mostly same from a month or two ago when I last flew.

It was good. Just that the seats could not be reclined. The people behind were not ready to let the chairs be reclined

Plane left & arrived early- 5 Crew great. Wi fi - paid for 2, only 1 worked - so so. Waste of $. Coolie was good

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

The plane was late and then sat on the runway for almost 45 minutes before taking off.

We kept being told that the flight was full and that all overhead compartments were full and therefore had to check in our hand luggage. We were some of the last people to board and noticed that there was still sufficient space in the overhead compartments. We were obliged to check in hand luggage when there was space and so had to wait at luggage retrieval which took a while to then noticed damage to our luggage - not a great experience!

This was an overnight flight. There was no meal service in first class, just a simple snack basket was offered along with beverages. There should have been some type of continental breakfast prior to arrival in PHL. As an Executive Platinum American Airlines Advantage member, I received no name recognition from the first class flight attendant. When disembarking at PHL, the flight attendants were more interested in their cell phones than saying "thank you" to the passengers as they disembarked.

The flight was quick and to the point. The crew just did their job w/o excessive talking and everything was just perfect.

Awkward carry on process. Forced to check all carry on. No overhead space of worthiness. Left delayed, but made up the time. Crew was amicable.

At least it was a short flight. Greyhound with wings.

late again! but its my only option to not take 9 hours to get to Memphis

Delays on all NY flights. There was no communication on why but they didn’t say it was weather. Other carriers were not delayed.

Amazingly comfy flight - I had upgraded for a reasonable price and it was worth it. The food also was good.

The seats were awful, hard plastic covered in sheet vinyl. The airline tries to scam you into paying extra to get seat together when the flight wasn’t full. They were going to separate a family with young children but my wife who had a row to herself gave up her seat so the young mom could be with her young boys. I’m never giving this airline my money again.

It was a short flight so no food or entertainment….

Frontier had yet another flight cancellation. Have never made a complete round trip with this airline without at least one leg getting cancelled. Miserable flights - dirty, uncomfortable planes that apparently always have issues since I've had multiple delays and cancellations with them.

Flight was delayed 3 times, would have been nice to have received text message instead of email notifications. Frontier app wasn’t even updated accordingly, no gate number disclosed. No agent at front desk of gate to inform of delay. Very confused and left if the dark

They changed the timing , first delayed by 4 hours then went back to 40 mins late, we had to run back to airport to not miss our flight. This is ridiculous

No frills for sure. No gate announcements about flight delay, not even water to drink on the flight.

I loked walking out on the tarmac to board and no first class. I didn't like that they have no snacks or onboard wifi to bide your time.

It was a redeye flight, so every passenger just wanted to sleep, but through the entire flight, the flight crew made announcements over the loudspeaker at maximum volume every few minutes making sleep impossible. For example: it’s 2am, and the crew decides to give an extremely detailed announcement about snacks and beverages for sale. And 3am is the perfect time to wake up everyone with a lengthy announcement about how to get a coffee refill and how to take advantage of new offer from frontier for a credit card.

The takeoff was the smoothest I've ever experienced on any airline and this is the first time I've flown on frontier so this was an extremely pleasant surprise!

A lady asked to stop the flight after the tunnel pulled away and we began to depart a flight that was already hours late. The attendance respectfully stopped the the plane and had the tunnel return. After the tunnel returned the passenger claimed to have changed her mind . The tunnel was then put in reverse and the passenger remained on the plane .. They should have sent the sick passenger off the plane like initially replaced. They existed a couple off the plane prior to that situation.. So.. all and all.. it was a long and flight.. .

Everything you need to know for your flight from San Diego to Knoxville

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