Which airports can I use when flying from San Diego to Knoxville?

Flights from San Diego to Knoxville usually depart from San Diego (SAN) and arrive at Knoxville McGhee Tyson (TYS).

What cabin classes can I book on flights from San Diego to Knoxville?

Only Economy Class is available on flights from San Diego to Knoxville.

Which airports do connecting flights from San Diego to Knoxville pass through?

One-stop flights from San Diego to Knoxville most commonly connect through: • Dallas/Fort Worth (DFW) - 53% of one-stop connections • Denver Intl (DEN) - 17% of one-stop connections • Atlanta Hartsfield-Jackson (ATL) - 14% of one-stop connections • Detroit Metropolitan Wayne County (DTW) - 4% of one-stop connections

Can I save money by using flexible dates for flights from San Diego to Knoxville?

Yes. Flexible dates can save you up to 24% on flights from San Diego to Knoxville. Saturday is the cheapest departure day at $407 round-trip on average, while Friday is the most expensive at $530, a difference of $123. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

How expensive are last-minute San Diego to Knoxville flights?

Last-minute fares on this route (booked within two weeks of departure) run 50% above the $459 route average. Book 19 weeks before departure for the lowest fares.

How long is a flight from San Diego to Knoxville?

A nonstop flight from San Diego to Knoxville takes 00m, covering 1,897 miles.

Do I need a passport to fly from San Diego to Knoxville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from San Diego to Knoxville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $243 to $1,983. That means the highest observed fare was about 8x higher than the lowest one.

How are flight prices from San Diego to Knoxville looking right now?

One-way fares from San Diego to Knoxville are currently lower than usual. Average one-way flight prices are about $174, which is 37% below the typical average for this route.

How much time can I save by choosing a different layover airport from San Diego to Knoxville?

Flying via Dallas Love Field (DAL) gives the shortest average 1-stop total travel time at 6h 50m, compared with 6h 51m via Houston George Bush Intcntl (IAH) and 6h 52m via Atlanta Hartsfield-Jackson (ATL).

What is the time difference between San Diego and Knoxville?

Knoxville is 3 hours ahead of San Diego (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $80 for economy cars. Top options include: • Budget • Alamo • Enterprise Rent-A-Car • Thrifty • Avis

How much should I expect to pay for a San Diego to Knoxville flight?

Round-trip flights from San Diego to Knoxville range from $378 to $558, with an average of $459 over the past 12 months. Anything below $378 counts as a good deal.

What's the cheapest day of the week to fly from San Diego to Knoxville?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from San Diego to Knoxville. It’s 12% cheaper than the average day, while Friday is the most expensive, with prices 15% higher.

What’s the cheapest month to fly from San Diego to Knoxville?

•May is the cheapest month to fly from San Diego to Knoxville at $414 round-trip. •November ($578) and October ($530) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 39% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from San Diego to Knoxville the cheapest?

Flights from San Diego to Knoxville are cheapest 19 weeks before departure. Booking in this window typically costs about 49% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Which airline is the cheapest to fly from San Diego to Knoxville?

Delta ($311) and Southwest ($316) are the cheapest airlines to fly round-trip from San Diego to Knoxville according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from San Diego to Knoxville?

Dallas/Fort Worth (DFW) is the most popular layover for the San Diego to Knoxville route. 53% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via DFW.

What is the cheapest layover airport when flying from San Diego to Knoxville?

Flights via Denver Intl (DEN) offer the most affordable fares, with an average round-trip price of $388. Based on KAYAK data over the past 3 months.

When flying from San Diego to Knoxville which airport offers the shortest layover?

Houston George Bush Intcntl (IAH) had the shortest average connection time for San Diego to Knoxville layovers at 3h 53m over the past 3 months.

$107 CHEAP FLIGHTS from San Diego to Knoxville (SAN - TYS)

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$243

Typical prices: $378-$558

Multiple Airlines

Sun 12/23Wed 1/10

SAN - TYS • 1 stop

Cheapest one-way

$107

Typical prices: $200-$361

Multiple Airlines

Sat 1/6

SAN - TYS • 1 stop

Nonstop flights

Not available

There are currently no direct flights between San Diego and Knoxville. You'll need to take a connecting flight to reach the destination.

Insights

When to book

19 weeks

in advance

Our data shows that travelers who book at least 19 weeks in advance save around 49% compared to booking last minute.

Insights

When to travel

May

Cheapest • 10% price drop

June

Most popular

Good to know

Top layover airports

Denver Intl (DEN)

Cheapest • Avg $388 (round-trip)

Dallas Love Field (DAL)

Shortest trip • 6h 50m (one-way)

Insights

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KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Knoxville!

Flight Deals

Cheap Flights from San Diego to Knoxville (SAN-TYS)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from San Diego to Knoxville

Fri, Dec 4 - Mon, Dec 7

9:05 am - 8:25 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 20m1 stop Las Vegas Harry Reid Intl

8:00 am - 11:58 pmTYS Knoxville McGhee Tyson-SAN San Diego

18h 58m2 stops Austin Bergstrom Denver Intl

$263Multiple Airlines

Fri, Dec 4 - Mon, Dec 7

9:05 am - 8:25 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 20m1 stop Las Vegas Harry Reid Intl

9:15 pm - 8:02 amTYS Knoxville McGhee Tyson-SAN San Diego

13h 47m1 stop Las Vegas Harry Reid Intl

$303Multiple Airlines

Wed, Dec 2 - Tue, Dec 8

12:31 pm - 11:24 pmSAN San Diego-TYS Knoxville McGhee Tyson

7h 53m1 stop Minneapolis St Paul

5:40 am - 11:54 amTYS Knoxville McGhee Tyson-SAN San Diego

9h 14m1 stop Atlanta Hartsfield-Jackson

$311Delta

Tue, Dec 1 - Tue, Dec 8

9:50 pm - 10:01 amSAN San Diego-TYS Knoxville McGhee Tyson

9h 11m1 stop Atlanta Hartsfield-Jackson

4:01 pm - 9:19 pmTYS Knoxville McGhee Tyson-SAN San Diego

8h 18m1 stop Atlanta Hartsfield-Jackson

$311Delta

Thu, Dec 3 - Tue, Dec 8

6:50 am - 5:00 pmSAN San Diego-TYS Knoxville McGhee Tyson

7h 10m1 stop Chicago O'Hare Intl

10:57 am - 5:15 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 18m2 stops Chicago O'Hare Intl Denver Intl

$316United Airlines

Wed, Dec 2 - Tue, Dec 8

6:35 am - 3:30 pmSAN San Diego-TYS Knoxville McGhee Tyson

5h 55m1 stop Denver Intl

7:05 am - 1:30 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 25m2 stops Nashville Intl Denver Intl

$316Southwest

Wed, Dec 2 - Tue, Dec 8

8:15 am - 7:50 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 35m2 stops Las Vegas Harry Reid Intl Nashville Intl

7:05 am - 1:40 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 35m2 stops Nashville Intl Austin Bergstrom

$341Southwest

Mon, Nov 23 - Thu, Nov 26

10:40 am - 8:54 pmSAN San Diego-TYS Knoxville McGhee Tyson

7h 14m1 stop Chicago O'Hare Intl

5:45 am - 11:43 amTYS Knoxville McGhee Tyson-SAN San Diego

8h 58m1 stop Washington, D.C. Dulles Intl

$343United Airlines

Mon, Nov 30 - Sat, Dec 12

9:45 pm - 8:49 amSAN San Diego-TYS Knoxville McGhee Tyson

8h 04m1 stop Charlotte Douglas

4:17 pm - 8:50 pmTYS Knoxville McGhee Tyson-SAN San Diego

7h 33m1 stop Charlotte Douglas

$354American Airlines

Sat, Nov 14 - Tue, Nov 17

6:15 am - 6:46 pmSAN San Diego-TYS Knoxville McGhee Tyson

9h 31m1 stop Charlotte Douglas

8:13 am - 1:08 pmTYS Knoxville McGhee Tyson-SAN San Diego

7h 55m1 stop Charlotte Douglas

$354American Airlines

Recent last minute flight deals from San Diego to Knoxville

Wed, Nov 4 - Wed, Nov 11

7:41 am - 6:46 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 05m1 stop Chicago O'Hare Intl

5:30 am - 12:11 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 41m1 stop Dallas/Fort Worth

$509American Airlines

Tue, Nov 3 - Mon, Nov 9

12:38 pm - 10:02 pmSAN San Diego-TYS Knoxville McGhee Tyson

6h 24m1 stop Atlanta Hartsfield-Jackson

7:22 pm - 11:32 pmTYS Knoxville McGhee Tyson-SAN San Diego

7h 10m1 stop Atlanta Hartsfield-Jackson

$509Delta

Wed, Nov 4 - Tue, Nov 10

10:16 am - 9:57 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 41m1 stop Houston George Bush Intcntl

1:56 pm - 6:34 pmTYS Knoxville McGhee Tyson-SAN San Diego

7h 38m1 stop Chicago O'Hare Intl

$509United Airlines

Wed, Nov 4 - Tue, Nov 10

12:05 pm - 9:57 pmSAN San Diego-TYS Knoxville McGhee Tyson

6h 52m1 stop Houston George Bush Intcntl

1:56 pm - 8:24 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 28m2 stops Chicago O'Hare Intl Los Angeles

$514United Airlines

Tue, Nov 3 - Mon, Nov 9

8:15 am - 7:45 pmSAN San Diego-TYS Knoxville McGhee Tyson

8h 30m2 stops Las Vegas Harry Reid Intl Nashville Intl

7:25 pm - 12:25 amTYS Knoxville McGhee Tyson-SAN San Diego

8h 00m1 stop Nashville Intl

$514Southwest

Wed, Nov 4 - Tue, Nov 10

6:45 am - 7:50 pmSAN San Diego-TYS Knoxville McGhee Tyson

10h 05m2 stops Phoenix Sky Harbor Intl Nashville Intl

7:05 am - 1:40 pmTYS Knoxville McGhee Tyson-SAN San Diego

9h 35m2 stops Nashville Intl Austin Bergstrom

$519Southwest

Sat, Oct 31 - Sat, Nov 7

4:53 pm - 2:11 pmSAN San Diego-TYS Knoxville McGhee Tyson

18h 18m1 stop Denver Intl

6:23 pm - 4:08 pmTYS Knoxville McGhee Tyson-SAN San Diego

24h 45m2 stops Tampa St. Petersburg Denver Intl

$520Multiple Airlines

Sun, Nov 1 - Tue, Nov 10

6:15 am - 3:26 pmSAN San Diego-TYS Knoxville McGhee Tyson

6h 11m1 stop Atlanta Hartsfield-Jackson

7:00 am - 11:38 amTYS Knoxville McGhee Tyson-SAN San Diego

7h 38m1 stop Atlanta Hartsfield-Jackson

$589Delta

Sun, Nov 1 - Fri, Nov 6

8:20 pm - 8:52 pmSAN San Diego-TYS Knoxville McGhee Tyson

21h 32m1 stop Las Vegas Harry Reid Intl

12:49 pm - 3:58 pmTYS Knoxville McGhee Tyson-SAN San Diego

30h 09m2 stops Houston Hobby Denver Intl

$595Multiple Airlines

Wed, Nov 4 - Wed, Nov 11

7:40 am - 11:32 pmSAN San Diego-TYS Knoxville McGhee Tyson

12h 52m2 stops Seattle/Tacoma Intl Dallas/Fort Worth

2:55 pm - 10:13 amTYS Knoxville McGhee Tyson-SAN San Diego

22h 18m2 stops Dallas/Fort Worth Seattle/Tacoma Intl

$751Alaska Airlines

Booking Insights

Price, demand and travel trends for San Diego to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

What's the cheapest day of the week to fly from San Diego to Knoxville?: Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from San Diego to Knoxville. It’s 12% cheaper than the average day, while Friday is the most expensive, with prices 15% higher.
What’s the cheapest month to fly from San Diego to Knoxville? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from San Diego to Knoxville, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •May is the cheapest month to fly from San Diego to Knoxville at $414 round-trip.
•November ($578) and October ($530) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 39% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.
When are flights from San Diego to Knoxville the cheapest?: Flights from San Diego to Knoxville are cheapest 19 weeks before departure. Booking in this window typically costs about 49% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Low season	October
High season	June
Cheapest flight	$107

Beat the crowds with an average 24% drop in travelers.

The most popular month to fly with an average 36% increase in travelers.

One-way flight from San Diego to Knoxville

When to book flights from San Diego to Knoxville

Are your dates flexible? Find out the best times to travel from San Diego to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from San Diego to Knoxville?
Only Economy Class is available on flights from San Diego to Knoxville.
How long is a flight from San Diego to Knoxville?
A nonstop flight from San Diego to Knoxville takes 00m, covering 1,897 miles.
Do I need a passport to fly from San Diego to Knoxville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a San Diego to Knoxville flight?
Round-trip flights from San Diego to Knoxville range from $378 to $558, with an average of $459 over the past 12 months. Anything below $378 counts as a good deal.
How expensive are last-minute San Diego to Knoxville flights?
Last-minute fares on this route (booked within two weeks of departure) run 50% above the $459 route average. Book 19 weeks before departure for the lowest fares.
Have flight prices from San Diego to Knoxville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $243 to $1,983. That means the highest observed fare was about 8x higher than the lowest one.
How are flight prices from San Diego to Knoxville looking right now?
One-way fares from San Diego to Knoxville are currently lower than usual. Average one-way flight prices are about $174, which is 37% below the typical average for this route.
What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?
Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $80 for economy cars. Top options include:

• Budget
• Alamo
• Enterprise Rent-A-Car
• Thrifty
• Avis
Which airports can I use when flying from San Diego to Knoxville?
Flights from San Diego to Knoxville usually depart from San Diego (SAN) and arrive at Knoxville McGhee Tyson (TYS).
Which airports do connecting flights from San Diego to Knoxville pass through?
One-stop flights from San Diego to Knoxville most commonly connect through:

• Dallas/Fort Worth (DFW) - 53% of one-stop connections
• Denver Intl (DEN) - 17% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 14% of one-stop connections
• Detroit Metropolitan Wayne County (DTW) - 4% of one-stop connections
Can I save money by using flexible dates for flights from San Diego to Knoxville?
Yes. Flexible dates can save you up to 24% on flights from San Diego to Knoxville. Saturday is the cheapest departure day at $407 round-trip on average, while Friday is the most expensive at $530, a difference of $123.

Cheaper weekend fares like these are typical of routes dominated by weekday business travel.
How much time can I save by choosing a different layover airport from San Diego to Knoxville?
Flying via Dallas Love Field (DAL) gives the shortest average 1-stop total travel time at 6h 50m, compared with 6h 51m via Houston George Bush Intcntl (IAH) and 6h 52m via Atlanta Hartsfield-Jackson (ATL).
What is the time difference between San Diego and Knoxville?
Knoxville is 3 hours ahead of San Diego (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Saturday departure and avoid flying on Friday. On this route, Saturday flights average $407, about $123 less than Friday fares (23% savings) based on the last 12 months.
For the best chance at a low fare, aim to book around 19 weeks before you fly. On this route, that window historically saves about 49% versus last-minute pricing (KAYAK booking data, last 12 months).
If you can choose when to travel, plan your San Diego to Knoxville trip for May. Fares historically average $414 round-trip in that month - typically $164 less than the most expensive month, which is November (based on the last 12 months).

More options for your flight from San Diego to Knoxville

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SAN - TYS

$107 Find Cheap Flights from San Diego to Knoxville - Compare and Save

Everything you should know

Cheap Flights from San Diego to Knoxville (SAN-TYS)

Recent round-trip flight deals from San Diego to Knoxville

Recent one-way flight deals from San Diego to Knoxville

Recent last minute flight deals from San Diego to Knoxville

Price, demand and travel trends for San Diego to Knoxville flights

What's the cheapest day of the week to fly from San Diego to Knoxville?

What’s the cheapest month to fly from San Diego to Knoxville?

When are flights from San Diego to Knoxville the cheapest?

Which airline is the cheapest to fly from San Diego to Knoxville?

What’s the most popular layover airport when flying from San Diego to Knoxville?

What is the cheapest layover airport when flying from San Diego to Knoxville?

When flying from San Diego to Knoxville which airport offers the shortest layover?

Key details for San Diego to Knoxville flights

Low season

High season

Cheapest flight

When to book flights from San Diego to Knoxville

Your San Diego to Knoxville flight questions, answered

Your guide to booking San Diego to Knoxville flights

More options for your flight from San Diego to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from San Diego to Knoxville

Find direct flights to and from San Diego and Knoxville

Flights from domestic origins to Knoxville

Flights to other popular destinations

Find deals for your return flight