SAN - TYS

$159 Find Cheap Flights from San Diego to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Diego to Knoxville departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Diego to Knoxville, as well as popular online travel agencies
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Flights Deals

Cheap Flights from San Diego to Knoxville (SAN-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Diego to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Diego to Knoxville

Fri, Sep 26 - Mon, Sep 29
 Logo
11:40 am - 10:30 pmSAN-TYS
7h 50m1 stop
 Logo
8:30 am - 2:11 pmTYS-SAN
8h 41m1 stop
Tue, Jul 1 - Tue, Jul 22
 Logo
7:31 pm - 1:12 pmSAN-TYS
14h 41m1 stop
 Logo
4:55 pm - 9:55 amTYS-SAN
20h 00m2 stops
Tue, Aug 26 - Wed, Sep 3
American Airlines Logo
10:45 pm - 11:22 amSAN-TYS
9h 37m1 stop
American Airlines Logo
6:00 am - 9:52 amTYS-SAN
6h 52m1 stop
$277American Airlines
Find Deal
Wed, Aug 20 - Sat, Aug 23
United Airlines Logo
10:54 am - 11:44 pmSAN-TYS
9h 50m2 stops
United Airlines Logo
4:40 pm - 8:25 pmTYS-SAN
6h 45m1 stop
$282United Airlines
Find Deal
Wed, Aug 6 - Sun, Aug 17
Delta Logo
6:15 am - 5:12 pmSAN-TYS
7h 57m1 stop
Delta Logo
6:14 pm - 11:21 pmTYS-SAN
8h 07m1 stop
$283Delta
Find Deal
Mon, Oct 20 - Mon, Oct 27
American Airlines Logo
11:00 pm - 8:27 amSAN-TYS
6h 27m1 stop
American Airlines Logo
6:31 pm - 12:03 amTYS-SAN
8h 32m1 stop
$288American Airlines
Find Deal
Wed, Jul 23 - Mon, Jul 28
Delta Logo
6:15 am - 5:24 pmSAN-TYS
8h 09m1 stop
Delta Logo
7:43 pm - 11:21 pmTYS-SAN
6h 38m1 stop
$293Delta
Find Deal
Sun, Jun 29 - Thu, Jul 3
Frontier Logo
6:25 am - 4:29 pmSAN-TYS
7h 04m1 stop
Frontier Logo
5:25 pm - 11:55 pmTYS-SAN
9h 30m1 stop
$340Frontier
Find Deal
Mon, Sep 22 - Sun, Sep 28
Frontier Logo
6:25 am - 7:41 pmSAN-TYS
10h 16m1 stop
Frontier Logo
8:26 pm - 11:50 pmTYS-SAN
6h 24m1 stop
$345Frontier
Find Deal
Fri, Sep 12 - Fri, Sep 19
United Airlines Logo
10:30 pm - 9:58 amSAN-TYS
8h 28m1 stop
United Airlines Logo
7:00 am - 11:40 amTYS-SAN
7h 40m1 stop
$354United Airlines
Find Deal
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KAYAK's insights & trends for San Diego to Knoxville flights

Get data-powered insights and trends into flights from San Diego to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from San Diego to Knoxville?

The average price of all round-trip flights from San Diego to Knoxville clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Knoxville on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from San Diego to Knoxville. For your return ticket, we recommend flying on a Wednesday and avoiding Sundays for the best deals.

What is the cheapest month to fly from San Diego to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Diego to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Diego to Knoxville is January, where tickets cost $318 (return) on average. On the other hand, the most expensive months are December and March, where the average cost of round-trip tickets is $548 and $503 respectively.

How far in advance should I book a flight from San Diego to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Diego to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Diego to Knoxville, you should book around 3 weeks before departure. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonJanuary
High seasonDecember
Cheapest flight$159
Best time to beat the crowds with an average 26% drop in price.
Most popular time to fly with an average 28% increase in price.
Flight from San Diego to Knoxville

When to book flights from San Diego to Knoxville

Are your dates flexible? Find out the best times to travel from San Diego to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Diego to Knoxville

  • What is the cheapest flight from San Diego to Knoxville?

    In the last 3 days, the lowest price for a flight from San Diego to Knoxville was $159 for a one-way ticket and $268 for a round-trip.

  • Do I need a passport to fly between San Diego and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from San Diego to Knoxville?

    On your way to Knoxville, you’ll fly out from San Diego. You’ll be landing at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from San Diego to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Diego to Knoxville?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between San Diego and Knoxville, with oneworld being the most commonly used for this route.

  • What is the most popular layover when flying to Knoxville from San Diego?

    Dallas is the most popular layover city among KAYAK users traveling from San Diego to Knoxville.

  • Which is the best airline for flights from San Diego to Knoxville, Delta or Alaska Airlines?

    The two airlines most popular with KAYAK users for flights from San Diego to Knoxville are Delta and Alaska Airlines. With an average price for the route of $391 and an overall rating of 8.0, Delta is the most popular choice. Alaska Airlines is also a great choice for the route, with an average price of $798 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from San Diego to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Diego to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Diego to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from San Diego is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Diego to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to San Diego with another airline. Booking your flights between San Diego and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Diego to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from San Diego up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from San Diego to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from San Diego to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Diego to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 10000 reviews
7.8Comfort
8.5Crew
8.1Boarding
7.1Entertainment
7.1Food
Airline reviews

The plane was delayed a bit. It wasn't a huge problem though, as we were heading back home.

8.0 ExcellentCarlos, Jun 2025SAN - AUS
Read more Alaska Airlines reviews

The plane was delayed a bit. It wasn't a huge problem though, as we were heading back home.

Flight was great. Boarding was crazy because another flight was boarding late next to ours so everyone was standing and in the way.

very good but no blankets for overnight flight or tv screens…

We were in 1st Class. Excellent service. Easy boarding. No too difficult to speak with someone on the phone. Breakfast was not eatable for me. No screen to watch movies. I don't have or want a tablet. This is first class there should be screens. Even if I had a tablet there was no place to put it. There is a place to put a tablet in economy. Seats were a bit lumpy.

A cheerful and effective crew. Tasty pre-order food options.

My youngest didn't have a assigned seat until we biard6the plane.

There was no seating at the gate, no where to charge your devices, super crowded. Boarding in group F meant all luggage space was taken when it was time for me to board. The boarding crew was short with everyone and seemed irritated. The luggage space was insufficient, the seat was too small for me (6'4") and very uncomfortable trip. I was in a middle seat between a person snoring the whole trip and a person with very strong body odor. The flight crew was terse and unfriendly, seemed irritated and impatient. Yelled a lot at people with earbuds in, understandable. Finally, we arrived 10 minutes early, only to sit on the tarmac for 20 minutes and wait for a gate. Worst flight experience I've had in years.

The flight was delayed by 3 hours and 30 minutes without any explanation.

A little delay but nice flight, nice team. Thank you.

They lock the bathrooms too soon before landing! My bladder was bursting for over an hour. Then the plane had to sit on the taxiway for 1 hour. People started rushing to the bathroom. Creating a dangerous situation.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

737-800 in first class was pretty dumpy. Seat had an uncomfortable angle, storage under the seat was blocked so even my very modest backpack didn't fit, power outlet was flaky. Weird tiny seat pockets that couldn't hold a gallon ziploc bag, emesis bag missing, etc. etc. No in-flight service due to turbulence. Crew was excellent, boarding was smooth despite a full flight.

Delta flight was on time, seats were comfortable, and crew was nice.

Thank you for not flipping the plane on the run way. You guys get a 5 star rating for the flight!!!

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

Kind staff. Snacks are small but that’s the new normal.

It was terrible, if they ran flights on time it would make a big difference.

Delta seems to be improving in many areas, except they are super bad with the food available. Bring back normal food service on long flights.

it was so bad. I tried to board my flight from vancouver to saskatoon. And to my surprise they did not board me cause the flight was changed and no email was send to me. and on my boarding pass which i got from seattle says different flight. I did not knew anyone from Vancouver, air canada crew was rude, i asked for today flight but they were rude and i had early morning dental appointment in saskatoon. I was so much in pain and my whole day is wasted today. and i suffered alot. They did provide me hotel but they did not provide me any food. I am really really disappointed first time had so bad experience with air canada. I may think twice to book it again. If i can get any reply or any composition that would be great. Thanks

Very comfortable (upgraded to business class). The audio on my screen didn’t work, but I managed to play the audio through my phone while watching the screen.

I was supposed to be on business class at first class from Denver back to Miami due to weather changes. I missed my connection and it’s put on a flight to Fort Lauderdale. Instead of honoring my business class/1st class ticket, they put me in coach, but there were two first class seats open. I think it’s absolutely disgusting that I paid for first class $1300 ticket and they put me in economy and they had to open seats available and I have still not been refunded the difference. I ended up having to eat a snack box instead of the meal I was supposed to get and did not get home till 2 AM so I think that’s a little pathetic that I had to live off crackers for dinner And my poor dog ate some cheese and salami. Oh yes, apparently when they switched me to the new flight they forgot to mention I had a service dog

Boarding seemed to be organized bedlam. For what ever reason, preboarding took longer than 20 minutes. Made the plane 20 minutes late taking off. Luckily we arrived on time. Flight crew seemed very friendly. Only slight turbulence.

The personnel were professional and friendly. The Boeing 737 Max 9 is too claustrophobic and was very warm at both airport gates, and still warm in the air.

While the staff was pleasant and helpful, the following observations are for your awareness. There was some delay on the tarmac on take off and landing. The paid lunch/food offerings were limited. Entertainment was only available on WiFi at a cost.

get E+, a must for 5 hours flight if you are tall

The first flight was better in terms of the aircraft.

The gate was too far away for the connecting flight

Compared with other carriers business class for an overnight was not worth the extra expense.

The chair cushions may need an upgrade. I have been noticing they are so worn out, thin so you’d sit in a dip 😄. Other than that, all was an enjoyable trip. Thanks AA!

Cramped seats. FAA should make airlines have more legroom, for even short people complain

Flight was full, and would have preferred an aisle seat, but due to getting a late ticket ,the seat I had was adequate. The flight crew were very help full and hard working. Food and drink were excellent for the 11hr flight. Overall I was pleased with flight, and would recommend British Airways again.

Eventless. It was a good flight and good crew. Can’t complaint.

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

The plane was late and then sat on the runway for almost 45 minutes before taking off.

We kept being told that the flight was full and that all overhead compartments were full and therefore had to check in our hand luggage. We were some of the last people to board and noticed that there was still sufficient space in the overhead compartments. We were obliged to check in hand luggage when there was space and so had to wait at luggage retrieval which took a while to then noticed damage to our luggage - not a great experience!

This was an overnight flight. There was no meal service in first class, just a simple snack basket was offered along with beverages. There should have been some type of continental breakfast prior to arrival in PHL. As an Executive Platinum American Airlines Advantage member, I received no name recognition from the first class flight attendant. When disembarking at PHL, the flight attendants were more interested in their cell phones than saying "thank you" to the passengers as they disembarked.

The flight was quick and to the point. The crew just did their job w/o excessive talking and everything was just perfect.

Awkward carry on process. Forced to check all carry on. No overhead space of worthiness. Left delayed, but made up the time. Crew was amicable.

Cancelled flight after I arrived at airport after 75 min drive and parking. Next flight was 4 days in the future. Had to scramble and buy a much more expensive flight on another carrier.

I liked the turn-style feature at gate 209B at LAX. Very efficient process. The gate staff also made several, clearly directed announcements so I felt very informed.

The seats were awful, hard plastic covered in sheet vinyl. The airline tries to scam you into paying extra to get seat together when the flight wasn’t full. They were going to separate a family with young children but my wife who had a row to herself gave up her seat so the young mom could be with her young boys. I’m never giving this airline my money again.

It was a short flight so no food or entertainment….

Frontier had yet another flight cancellation. Have never made a complete round trip with this airline without at least one leg getting cancelled. Miserable flights - dirty, uncomfortable planes that apparently always have issues since I've had multiple delays and cancellations with them.

Flight was delayed 3 times, would have been nice to have received text message instead of email notifications. Frontier app wasn’t even updated accordingly, no gate number disclosed. No agent at front desk of gate to inform of delay. Very confused and left if the dark

They changed the timing , first delayed by 4 hours then went back to 40 mins late, we had to run back to airport to not miss our flight. This is ridiculous

No frills for sure. No gate announcements about flight delay, not even water to drink on the flight.

I loked walking out on the tarmac to board and no first class. I didn't like that they have no snacks or onboard wifi to bide your time.

It was a redeye flight, so every passenger just wanted to sleep, but through the entire flight, the flight crew made announcements over the loudspeaker at maximum volume every few minutes making sleep impossible. For example: it’s 2am, and the crew decides to give an extremely detailed announcement about snacks and beverages for sale. And 3am is the perfect time to wake up everyone with a lengthy announcement about how to get a coffee refill and how to take advantage of new offer from frontier for a credit card.

Everything you need to know for your flight from San Diego to Knoxville

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