TYS - SFO

$122 Find Cheap Flights from Knoxville to San Francisco - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to San Francisco departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$244
Typical prices: $373-$511
Frontier
Wed 8/5Wed 8/12
TYS - SFO • 1 stop
Cheapest one-way
$122
Typical prices: $204-$269
Frontier
Wed 8/5
TYS - SFO • 1 stop
Top airlines
Cheapest • from $244 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and San Francisco. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $365 (round-trip)
Shortest trip • 7h 50m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 37% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 32% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to San Francisco (TYS-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to San Francisco

Wed, Aug 5 - Wed, Aug 12
Frontier Logo
8:19 pm - 12:18 am
TYS
-
SFO
6h 59m
1 stop
Frontier Logo
6:00 am - 7:24 pm
SFO
-
TYS
10h 24m
1 stop
$244Frontier
Wed, Aug 5 - Wed, Aug 12
Frontier Logo
8:19 pm - 12:18 am
TYS
-
SFO
6h 59m
1 stop
Frontier Logo
6:00 am - 7:24 pm
SFO
-
TYS
10h 24m
1 stop
$245Frontier
Mon, Jul 27 - Wed, Aug 5
Frontier Logo
8:19 pm - 12:23 am
TYS
-
SFO
7h 04m
1 stop
Frontier Logo
6:00 am - 7:24 pm
SFO
-
TYS
10h 24m
1 stop
$269Frontier
Fri, Aug 7 - Wed, Aug 12
Frontier Logo
8:19 pm - 12:18 am
TYS
-
SFO
6h 59m
1 stop
Frontier Logo
6:00 am - 7:24 pm
SFO
-
TYS
10h 24m
1 stop
$271Frontier
Mon, Aug 3 - Tue, Aug 11
Frontier Logo
8:19 pm - 12:23 am
TYS
-
SFO
7h 04m
1 stop
Frontier Logo
12:38 pm - 7:24 pm
SFO
-
TYS
27h 46m
1 stop
$272Frontier
Fri, Jul 31 - Tue, Aug 4
Frontier Logo
8:19 pm - 12:23 am
TYS
-
SFO
7h 04m
1 stop
Frontier Logo
12:38 pm - 7:24 pm
SFO
-
TYS
27h 46m
1 stop
$281Frontier
Mon, Aug 10 - Mon, Aug 17
Frontier Logo
8:19 pm - 12:18 am
TYS
-
SFO
6h 59m
1 stop
Frontier Logo
6:00 am - 7:24 pm
SFO
-
TYS
10h 24m
1 stop
$298Frontier
Mon, Aug 10 - Tue, Aug 18
Multiple Airlines Logo
2:47 pm - 3:20 pm
TYS
-
SFO
27h 33m
1 stop
Multiple Airlines Logo
1:07 pm - 1:49 pm
SFO
-
TYS
45h 42m
2 stops
$305Multiple Airlines
Fri, Jul 24 - Sun, Jul 26
Frontier Logo
8:19 pm - 12:23 am
TYS
-
SFO
7h 04m
1 stop
Frontier Logo
9:39 pm - 7:24 pm
SFO
-
TYS
18h 45m
1 stop
$308Frontier
Wed, Jul 15 - Wed, Jul 22
Frontier Logo
8:19 pm - 12:23 am
TYS
-
SFO
7h 04m
1 stop
Frontier Logo
6:00 am - 7:24 pm
SFO
-
TYS
10h 24m
1 stop
$309Frontier
Booking Insights

KAYAK's insights & trends for Knoxville to San Francisco flights

Get data-powered insights and trends into flights from Knoxville to San Francisco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to San Francisco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to San Francisco departing in August.

What is the cheapest month to fly from Knoxville to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to San Francisco is February, where tickets cost $329 (return) on average. On the other hand, the most expensive months are June and May, where the average cost of round-trip tickets is $702 and $658 respectively.

How far in advance should I book a flight from Knoxville to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Knoxville to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Knoxville to San Francisco, you should book around 3 weeks before departure, which saves you about 37% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 20 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$122
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from Knoxville to San Francisco

When to book flights from Knoxville to San Francisco

Are your dates flexible? Find out the best times to travel from Knoxville to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to San Francisco

  • What is the cheapest flight from Knoxville to San Francisco?

    In the last 5 days, the lowest price for a flight from Knoxville to San Francisco was $122 for a one-way ticket and $244 for a round-trip.

  • Do I need a passport to fly between Knoxville and San Francisco?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Knoxville to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to San Francisco?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Knoxville and San Francisco, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to San Francisco, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to San Francisco are Delta and United Airlines. With an average price for the route of $472 and an overall rating of 7.8, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $498 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Knoxville to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Knoxville to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8454 reviews
7.8Entertainment
7.2Food
8.1Boarding
8.5Crew
7.8Comfort
Airline reviews

We sat on the runway for over an hour before departure. That was unwelcome.

6.0 GoodAnonymous, Jun 2026
SEA - SFO
Read more Delta reviews

We sat on the runway for over an hour before departure. That was unwelcome.

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

WiFi didn’t work most of the time. The usb chargers would work only occasionally for 5 mins and wouldn’t charge after that. Had to keep trying repeatedly at each of the seats in the row.

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

The staff was extremely helpful and friendly at all times! They went above and beyond to get us into an earlier flight in San Diego to make our connection in SFO possible, because our original flight did actually not make it! I did so much appreciate the UA team and how they made this possible. We also didn’t have seats together on the long flight to Singapore, but they found us seats together last moment with no additional cost! Nobody sat next to us, so that we were able to sleep! Thanks to UA for improving their service and Underpricer for booking this trip! Please be careful: 1,5 hrs for transfer in San Francisco might not be enough time in the future

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

6 1/2 hours from Tampa to SFO on a Boeing 737. Cramped. No Service. No real food. One pass for coffee at the beginning and a second pass THREE hours later. And check-in in Tampa was nasty even by United standards. And I am at almost TWO million miles on United. It's a non-stop. But terrible service.

First class ticket gets you no seat back entertainment? I have to bring my own laptop to see a movie? And most of their movies have ADS? No thank you. Worse: Tiny snacks only on a 2 hr flight?

Late plane. Only one crew on the ground so we b had to wait for Denver flight to come in, board, and depart. At 78 yrs of age I was not pleased trying to get my connection. What really made me angry was the notification you sent me to hurry up or I would miss my connection. Why tell me to hurry up when you got me in late. It was not a good way of treating customers.

No complaints other than luggage carousel was incorrectly guiding passengers to the wrong carousel on the screen.

The flight was delayed from take off because only one runway was operational in San Francisco.

The internet service I paid for didn’t work at all and the flight crew was not very friendly.

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Long 5 hour and 45 min flight and only one drink service and cookie snack

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

We boarded after several delays due to mechanical failure and a gate change. The seat cushion in the exit row was very compressed and offered no cushion, making the four-hour journey reasonably uncomfortable. The WiFi worked for a few people, but for most, it did not, and you cannot get entertainment unless you can connect—American Airlines flights do not have seatback screens, and you must use your mobile phone.

For coast to coast travel the A321 and even the NEO, even in first class will never be excellent. That would take a B787 or 777 to accomplish.

Charges unexpected. For seat that didnt recline. Please reverse extra seat and carryon charge. Bad business that is a bait and switch.

I couldn’t check in because the app didn’t work. It took 3 Frontier employees at the counter to get me checked in. Flight left 3 hours after departure time

Horrible! The short distance flight ended up taking 5 hrs! There was a 3 hr delay for the flight to take off and there was a 70 min wait on the tarmac for some bogus reason that the pilot said the gate he was supposed to board was taken up. After a 30 min wait he said the plane that was supposed to push out of the gate called a medical emergency and 40 min later he ended up boarding another gate. For the initial 3 hr delay there was no information/alert about the gate or delay in the app or the boards up until the boarding time and even beyond! Had to walk all the way to the end of the terminal to find the frontier staff to ask what was going on. Avoid this airline at all costs! If you have carryon bags or checked bags , their prices come equivalent to the prices of more reliable airlines. They are the worst in timeliness at 60% (reported as delayed) this year (check the data) by a high margin even compared to the second worst airline. If you are ok with having a miserable flight experience with the odds close to flip of a coin, feel free to try them. If you value your time , money and flying experience, stay away.

Our flight was delayed by four hours without notice, the app for getting my boarding pass is super confusing, and I wasn’t able to check a suitcase without paying for a higher cost package

First the gate was a total nightmare-no chairs anywhere! So over crowded and only one bathroom and nightmare of food service - took forever and NOT one place to sit. No inflight entertainment and had to pay 60.00 for a small carry on. I will never fly Frontier again!

Flight was 3 hours late leaving. Poor communication from the staff about delays. Impossible to get in touch with customer service (by design). And it actually didn't come out to be much cheaper than a non-budget airline! Not worth the headache, I'm never flying Frontier again

See my previous comment which is mostly about our flight from Phoenix to SFO

The check in at the airport was awful. Told I need to pay for a bag. The item was taken at screening. I went back to get my $ back and they gave me a coupon with a QR code that doesn’t work. Worst costumer service ever!!!!!

4 hour delay because they used our aircraft to fly a different segment (per the captain)

absolutely horrific. delayed flights, overbooking. over charging. nightmare service beyond words. stay away.

Everything you need to know for your flight from Knoxville to San Francisco

Information on your arrival and departure airports