SFO - TYS

$155 Find Cheap Flights from San Francisco to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Knoxville departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Knoxville, as well as popular online travel agencies
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Cheap Flights from San Francisco to Knoxville (SFO-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Knoxville

Mon, Jul 14 - Mon, Jul 21
United Airlines Logo
11:25 pm - 10:17 amSFO-TYS
7h 52m1 stop
United Airlines Logo
7:35 pm - 12:57 amTYS-SFO
8h 22m1 stop
$309United Airlines
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Sat, Oct 4 - Thu, Oct 9
Delta Logo
6:00 am - 6:13 pmSFO-TYS
9h 13m1 stop
Delta Logo
6:05 pm - 11:49 pmTYS-SFO
8h 44m1 stop
$319Delta
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Sun, Aug 10 - Tue, Aug 12
United Airlines Logo
5:00 am - 3:18 pmSFO-TYS
7h 18m1 stop
United Airlines Logo
7:00 am - 12:16 pmTYS-SFO
8h 16m1 stop
$326United Airlines
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Fri, Jul 4 - Fri, Jul 11
American Airlines Logo
10:17 pm - 8:34 amSFO-TYS
7h 17m1 stop
American Airlines Logo
6:22 pm - 12:08 amTYS-SFO
8h 46m1 stop
$339American Airlines
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Thu, Jul 17 - Mon, Jul 21
 Logo
11:59 pm - 4:12 pmSFO-TYS
13h 13m1 stop
 Logo
11:01 am - 10:53 pmTYS-SFO
14h 52m1 stop
Wed, Jul 30 - Sat, Aug 2
American Airlines Logo
7:13 am - 6:02 pmSFO-TYS
7h 49m1 stop
American Airlines Logo
5:05 am - 12:14 pmTYS-SFO
10h 09m1 stop
$341American Airlines
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Thu, Sep 11 - Mon, Sep 15
Frontier Logo
6:00 am - 7:41 pmSFO-TYS
10h 41m1 stop
Frontier Logo
8:26 pm - 12:14 amTYS-SFO
6h 48m1 stop
$360Frontier
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Mon, Jul 21 - Thu, Jul 24
Delta Logo
10:40 pm - 10:14 amSFO-TYS
8h 34m1 stop
Delta Logo
6:19 pm - 12:40 amTYS-SFO
9h 21m1 stop
$384Delta
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Thu, Oct 30 - Sun, Nov 2
Frontier Logo
6:00 am - 4:14 pmSFO-TYS
7h 14m1 stop
Frontier Logo
5:14 pm - 12:14 amTYS-SFO
10h 00m1 stop
$490Frontier
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Wed, Jul 30 - Wed, Aug 6
Alaska Airlines Logo
6:00 am - 9:46 pmSFO-TYS
12h 46m2 stops
Alaska Airlines Logo
12:20 pm - 9:37 pmTYS-SFO
12h 17m2 stops
$728Alaska Airlines
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KAYAK's insights & trends for San Francisco to Knoxville flights

Get data-powered insights and trends into flights from San Francisco to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from San Francisco to Knoxville?

The average price of all round-trip flights from San Francisco to Knoxville clicked on KAYAK for each day over the last 12 months.

When flying from San Francisco to Knoxville, you should consider leaving on a Tuesday and avoid Fridays if you are looking for the best rates. For your return to San Francisco, you’ll find the best rates on Tuesdays and the most expensive ones on Mondays.

What is the cheapest month to fly from San Francisco to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Knoxville is August, where tickets cost $413 (return) on average. On the other hand, the most expensive months are December and June, where the average cost of round-trip tickets is $588 and $553 respectively.

How far in advance should I book a flight from San Francisco to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Knoxville, you should book around 3 weeks before departure. For the absolute cheapest price, our data suggests you should book 19 weeks before departure.

Good to know

Low seasonFebruary
High seasonJuly
Cheapest flight$155
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from San Francisco to Knoxville

When to book flights from San Francisco to Knoxville

Are your dates flexible? Find out the best times to travel from San Francisco to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Francisco to Knoxville

  • What are the transportation options to get from the McGhee Tyson Airport (TYS) to downtown Knoxville?

    Since there are no public transportation options that offer service from the airport to the downtown area, the best choice for most travelers is to take one of the readily available taxis outside of the terminal building that will make the trip in about 18min.

  • Where should I be looking for my rental car company when I arrive at the airport in Knoxville?

    There are roughly 8 different rental car companies that operate at this airport, and every one of them has a customer service counter on the lower level of the airport terminal building adjacent to the baggage claim area. All vehicles for rent sit just outside of the exit doors from the baggage claim area in the adjacent parking lots.

  • Where should I plan on meeting my rideshare ride after my flight to Knoxville?

    All rideshare companies do their pick-ups on the lower level of the terminal building just outside of the baggage claim area. When you exit the baggage claim area of the terminal building, you will see signage for pick-up locations just to the right.

  • Are there any hotels that have a convenient location close to the terminal buildings at the airport in Knoxville?

    One of the most convenient choices is Hilton Knoxville Airport, which has a location right on the airport property. When you walk out of the terminal building, you will see this hotel just a few steps from the terminal building to your right just before the Economy Parking Lot B.

  • What is the cheapest flight from San Francisco to Knoxville?

    In the last 3 days, the lowest price for a flight from San Francisco to Knoxville was $155 for a one-way ticket and $309 for a round-trip.

  • Do I need a passport to fly between San Francisco and Knoxville?

    No

  • Which airports will I be using when flying from San Francisco to Knoxville?

    San Francisco airport is called San Francisco and the only airport in Knoxville is Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from San Francisco to Knoxville?

    The Embraer 175 is the aircraft model that flies most regularly on the San Francisco to Knoxville flight route.

  • Which airline alliances offer flights from San Francisco to Knoxville?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between San Francisco and Knoxville, with oneworld being the most commonly used for this route.

  • What is the most popular layover when flying to Knoxville from San Francisco?

    Dallas is the most popular layover city among KAYAK users traveling from San Francisco to Knoxville.

  • Which is the best airline for flights from San Francisco to Knoxville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from San Francisco to Knoxville are Delta and United Airlines. With an average price for the route of $433 and an overall rating of 8.0, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $583 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from San Francisco to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to San Francisco with another airline. Booking your flights between San Francisco and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from San Francisco to Knoxville

  • A fantastic way to get to the San Francisco International Airport (SFO) from the downtown area without having to drive your own car is to take the BART Yellow Line light rail train that can make the trip from the downtown area to the airport in 29 minutes.
  • If you plan on getting dropped off at the San Francisco International Airport before your flight, a good choice for a drop-off point is the Kiss and Fly location adjacent to the rental car center at the airport. This allows passengers to take their time getting dropped off, and then they can ride aboard the AirTrain Blue Line to the terminal building from the rental car center.
  • Parents who plan on taking their kids through the San Francisco International Airport before a flight to Knoxville should know that the airport offers an interactive play area in terminal two that lets kids have some fun and expend some energy before a long flight.
  • Travelers making their way to Knoxville with a pet or a service animal should know that the San Francisco International Airport offers seven different pet relief areas both outside and inside the terminal buildings at the airport. All of the relief areas have things like drinking bowls and waste gloves with disposal areas.
  • If you plan on flying to Knoxville from the San Francisco International Airport and want a comfortable place to wait for your flight, the San Francisco International Airport offers airline lounges from United Airlines, Alaska Airlines, Delta Airlines, and American Airlines that all offer plenty of comfortable seating options as well as a wide selection of food and beverage choices.

Reviews of the top 4 airlines serving from San Francisco to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7964 reviews
8.5Crew
8.2Boarding
7.3Food
7.9Entertainment
7.9Comfort
Airline reviews

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

8.0 ExcellentMathew, Jun 2025SAN - JFK
Read more Delta reviews

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

737-800 in first class was pretty dumpy. Seat had an uncomfortable angle, storage under the seat was blocked so even my very modest backpack didn't fit, power outlet was flaky. Weird tiny seat pockets that couldn't hold a gallon ziploc bag, emesis bag missing, etc. etc. No in-flight service due to turbulence. Crew was excellent, boarding was smooth despite a full flight.

Delta flight was on time, seats were comfortable, and crew was nice.

Thank you for not flipping the plane on the run way. You guys get a 5 star rating for the flight!!!

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

Kind staff. Snacks are small but that’s the new normal.

It was terrible, if they ran flights on time it would make a big difference.

Delta seems to be improving in many areas, except they are super bad with the food available. Bring back normal food service on long flights.

Very comfortable (upgraded to business class). The audio on my screen didn’t work, but I managed to play the audio through my phone while watching the screen.

Flight was late as pilot crew had to land at different airport in their previous flight. Passengers boarded and had to wait for pilots inside plane. Series of incomplete and unnecessary announcements by an annoying voice, rather than complete, informative announcements.

Breakfast was not loaded at SFO due to catering company change. Seems like a major airline at a major hub would have thought of something else or warned passengers to pick up food before boarding a 3 hour flight.

Boarding seemed to be organized bedlam. For what ever reason, preboarding took longer than 20 minutes. Made the plane 20 minutes late taking off. Luckily we arrived on time. Flight crew seemed very friendly. Only slight turbulence.

They hired a new catering company the same day of my flight. They botched the job by not delivering the right carts and after THREE HOURS waiting, the flight crew timed out (flight was 19 hours long and FAA rules state crew can’t work more than 14 hours long). So they CANCELED OUR FLIGHT!! Worst experience ever. Avoid UAL at all costs.

The personnel were professional and friendly. The Boeing 737 Max 9 is too claustrophobic and was very warm at both airport gates, and still warm in the air.

While the staff was pleasant and helpful, the following observations are for your awareness. There was some delay on the tarmac on take off and landing. The paid lunch/food offerings were limited. Entertainment was only available on WiFi at a cost.

get E+, a must for 5 hours flight if you are tall

Liked fold flat bed. Didn’t like having no window. Didn’t like poor choice of food and being served dinner very late, hours after take off of a 7:40pm flight. Servers not friendly. Food horrible in business class.

Compared with other carriers business class for an overnight was not worth the extra expense.

The chair cushions may need an upgrade. I have been noticing they are so worn out, thin so you’d sit in a dip 😄. Other than that, all was an enjoyable trip. Thanks AA!

Cramped seats. FAA should make airlines have more legroom, for even short people complain

Eventless. It was a good flight and good crew. Can’t complaint.

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

British Airways staff are very polite and willing to help.

The plane was late and then sat on the runway for almost 45 minutes before taking off.

We kept being told that the flight was full and that all overhead compartments were full and therefore had to check in our hand luggage. We were some of the last people to board and noticed that there was still sufficient space in the overhead compartments. We were obliged to check in hand luggage when there was space and so had to wait at luggage retrieval which took a while to then noticed damage to our luggage - not a great experience!

This was an overnight flight. There was no meal service in first class, just a simple snack basket was offered along with beverages. There should have been some type of continental breakfast prior to arrival in PHL. As an Executive Platinum American Airlines Advantage member, I received no name recognition from the first class flight attendant. When disembarking at PHL, the flight attendants were more interested in their cell phones than saying "thank you" to the passengers as they disembarked.

The flight was quick and to the point. The crew just did their job w/o excessive talking and everything was just perfect.

Awkward carry on process. Forced to check all carry on. No overhead space of worthiness. Left delayed, but made up the time. Crew was amicable.

Cancelled flight after I arrived at airport after 75 min drive and parking. Next flight was 4 days in the future. Had to scramble and buy a much more expensive flight on another carrier.

I liked the turn-style feature at gate 209B at LAX. Very efficient process. The gate staff also made several, clearly directed announcements so I felt very informed.

The seats were awful, hard plastic covered in sheet vinyl. The airline tries to scam you into paying extra to get seat together when the flight wasn’t full. They were going to separate a family with young children but my wife who had a row to herself gave up her seat so the young mom could be with her young boys. I’m never giving this airline my money again.

It was a short flight so no food or entertainment….

Frontier had yet another flight cancellation. Have never made a complete round trip with this airline without at least one leg getting cancelled. Miserable flights - dirty, uncomfortable planes that apparently always have issues since I've had multiple delays and cancellations with them.

Flight was delayed 3 times, would have been nice to have received text message instead of email notifications. Frontier app wasn’t even updated accordingly, no gate number disclosed. No agent at front desk of gate to inform of delay. Very confused and left if the dark

They changed the timing , first delayed by 4 hours then went back to 40 mins late, we had to run back to airport to not miss our flight. This is ridiculous

No frills for sure. No gate announcements about flight delay, not even water to drink on the flight.

I loked walking out on the tarmac to board and no first class. I didn't like that they have no snacks or onboard wifi to bide your time.

It was a redeye flight, so every passenger just wanted to sleep, but through the entire flight, the flight crew made announcements over the loudspeaker at maximum volume every few minutes making sleep impossible. For example: it’s 2am, and the crew decides to give an extremely detailed announcement about snacks and beverages for sale. And 3am is the perfect time to wake up everyone with a lengthy announcement about how to get a coffee refill and how to take advantage of new offer from frontier for a credit card.

Everything you need to know for your flight from San Francisco to Knoxville

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