SFO - TYS

$115 Find Cheap Flights from San Francisco to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Knoxville departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$256
Overall average: $498
Frontier
Do 4/16So 4/19
SFO - TYS • 1 stop
Cheapest one-way
$115
Typical prices: $235-$371
Multiple Airlines
Di 3/3
SFO - TYS • 1 stop
Top airlines
Frontier
Cheapest • from $256 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 27% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
August
Cheapest • 19% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Francisco to Knoxville (SFO-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Knoxville

Do, Apr 16 - So, Apr 19
Frontier Logo
6:00 am - 3:33 pm
SFO
-
TYS
6h 33m
1 stop
Frontier Logo
4:28 pm - 9:08 am
TYS
-
SFO
19h 40m
1 stop
$256Frontier
Di, Mrz 3 - Di, Mrz 10
Multiple Airlines Logo
7:15 pm - 7:03 pm
SFO
-
TYS
20h 48m
1 stop
Multiple Airlines Logo
9:00 am - 8:09 pm
TYS
-
SFO
14h 09m
2 stops
$259Multiple Airlines
Do, Apr 16 - So, Apr 19
Frontier Logo
6:00 am - 3:33 pm
SFO
-
TYS
6h 33m
1 stop
Frontier Logo
4:28 pm - 9:08 am
TYS
-
SFO
19h 40m
1 stop
$301Frontier
Mi, Mrz 11 - Mo, Mrz 16
Multiple Airlines Logo
6:00 am - 10:44 am
SFO
-
TYS
25h 44m
2 stops
Multiple Airlines Logo
4:20 pm - 12:28 am
TYS
-
SFO
11h 08m
1 stop
$321Multiple Airlines
Do, Feb 26 - Mo, Mrz 2
Multiple Airlines Logo
6:15 am - 10:07 pm
SFO
-
TYS
12h 52m
2 stops
Multiple Airlines Logo
8:13 pm - 10:01 pm
TYS
-
SFO
28h 48m
1 stop
$323Multiple Airlines
Mo, Feb 23 - Do, Feb 26
Multiple Airlines Logo
8:48 am - 7:18 pm
SFO
-
TYS
7h 30m
1 stop
Multiple Airlines Logo
5:53 pm - 8:03 am
TYS
-
SFO
41h 10m
2 stops
$325Multiple Airlines
So, Apr 26 - Sa, Mai 2
United Airlines Logo
11:20 pm - 10:50 am
SFO
-
TYS
8h 30m
1 stop
United Airlines Logo
7:00 am - 12:25 pm
TYS
-
SFO
8h 25m
1 stop
$329United Airlines
Fr, Feb 20 - So, Feb 22
Multiple Airlines Logo
8:48 am - 7:27 pm
SFO
-
TYS
7h 39m
1 stop
Multiple Airlines Logo
5:56 pm - 9:39 pm
TYS
-
SFO
30h 43m
2 stops
$338Multiple Airlines
Fr, Feb 27 - So, Mrz 1
Multiple Airlines Logo
6:15 am - 6:06 pm
SFO
-
TYS
8h 51m
1 stop
Multiple Airlines Logo
8:30 am - 8:17 am
TYS
-
SFO
26h 47m
1 stop
$343Multiple Airlines
Mo, Feb 23 - Do, Feb 26
United Airlines Logo
11:59 pm - 10:12 am
SFO
-
TYS
7h 13m
1 stop
United Airlines Logo
7:25 pm - 1:28 am
TYS
-
SFO
9h 03m
1 stop
$365United Airlines
Booking Insights

KAYAK's insights & trends for San Francisco to Knoxville flights

Get data-powered insights and trends into flights from San Francisco to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Francisco to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Knoxville is August, where tickets cost $383 (return) on average. On the other hand, the most expensive months are November and June, where the average cost of round-trip tickets is $573 and $534 respectively.

How far in advance should I book a flight from San Francisco to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Knoxville, you should book around 3 weeks before departure, which saves you about 27% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$115
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly with an average 13% increase in price.
Flight from San Francisco to Knoxville

When to book flights from San Francisco to Knoxville

Are your dates flexible? Find out the best times to travel from San Francisco to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Francisco to Knoxville

  • What are the transportation options to get from the McGhee Tyson Airport (TYS) to downtown Knoxville?

    Since there are no public transportation options that offer service from the airport to the downtown area, the best choice for most travelers is to take one of the readily available taxis outside of the terminal building that will make the trip in about 18min.

  • Where should I be looking for my rental car company when I arrive at the airport in Knoxville?

    There are roughly 8 different rental car companies that operate at this airport, and every one of them has a customer service counter on the lower level of the airport terminal building adjacent to the baggage claim area. All vehicles for rent sit just outside of the exit doors from the baggage claim area in the adjacent parking lots.

  • Where should I plan on meeting my rideshare ride after my flight to Knoxville?

    All rideshare companies do their pick-ups on the lower level of the terminal building just outside of the baggage claim area. When you exit the baggage claim area of the terminal building, you will see signage for pick-up locations just to the right.

  • Are there any hotels that have a convenient location close to the terminal buildings at the airport in Knoxville?

    One of the most convenient choices is Hilton Knoxville Airport, which has a location right on the airport property. When you walk out of the terminal building, you will see this hotel just a few steps from the terminal building to your right just before the Economy Parking Lot B.

  • What is the cheapest flight from San Francisco to Knoxville?

    In the last 3 days, the lowest price for a flight from San Francisco to Knoxville was $115 for a one-way ticket and $256 for a round-trip.

  • Do I need a passport to fly between San Francisco and Knoxville?

    No

  • Which airports will I be using when flying from San Francisco to Knoxville?

    San Francisco airport is called San Francisco and the only airport in Knoxville is Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from San Francisco to Knoxville?

    The Embraer 175 is the aircraft model that flies most regularly on the San Francisco to Knoxville flight route.

  • Which airline alliances offer flights from San Francisco to Knoxville?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between San Francisco and Knoxville, with Star Alliance being the most commonly used for this route.

  • What is the most popular layover when flying to Knoxville from San Francisco?

    Dallas is the most popular layover city among KAYAK users traveling from San Francisco to Knoxville.

  • Which is the best airline for flights from San Francisco to Knoxville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from San Francisco to Knoxville are Delta and United Airlines. With an average price for the route of $420 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $552 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from San Francisco to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to San Francisco with another airline. Booking your flights between San Francisco and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from San Francisco to Knoxville

  • A fantastic way to get to the San Francisco International Airport (SFO) from the downtown area without having to drive your own car is to take the BART Yellow Line light rail train that can make the trip from the downtown area to the airport in 29 minutes.
  • If you plan on getting dropped off at the San Francisco International Airport before your flight, a good choice for a drop-off point is the Kiss and Fly location adjacent to the rental car center at the airport. This allows passengers to take their time getting dropped off, and then they can ride aboard the AirTrain Blue Line to the terminal building from the rental car center.
  • Parents who plan on taking their kids through the San Francisco International Airport before a flight to Knoxville should know that the airport offers an interactive play area in terminal two that lets kids have some fun and expend some energy before a long flight.
  • Travelers making their way to Knoxville with a pet or a service animal should know that the San Francisco International Airport offers seven different pet relief areas both outside and inside the terminal buildings at the airport. All of the relief areas have things like drinking bowls and waste gloves with disposal areas.
  • If you plan on flying to Knoxville from the San Francisco International Airport and want a comfortable place to wait for your flight, the San Francisco International Airport offers airline lounges from United Airlines, Alaska Airlines, Delta Airlines, and American Airlines that all offer plenty of comfortable seating options as well as a wide selection of food and beverage choices.

Reviews of the top 4 airlines serving from San Francisco to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8130 reviews
7.8Entertainment
7.2Food
7.9Comfort
8.5Crew
8.1Boarding
Airline reviews

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

10.0 ExcellentDr. Simon, Jan 2026
LAX - JFK
Read more Delta reviews

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

The flight was delayed for about 2 hrs. Other than it, it was good.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

The flight crew where really good. Better then the crew from BNE to SFO

Food should be changed in menu Many muslims travels in this airlime they need to add one Halal meal

left on time, reasonable boarding process arrived early luggage came out quickly

Pushed back only to get deplaned due to a tire damaged by ground crew. They did at least go pretty fast. The bathrooms should be banned under the Geneva convention. No room to even sit straight on the toilet. The under-seat entertainment units block what little leg room there is.

United airlines has the best customer experience from booking to arrival. I always fly United airlines. The mileage program is excellent

Older aircraft, no meal, only food was for purchase. Not impressed United.

Not pleasant trip cross country when the entertainment and WiFi system not working. No entertainment for entirety of route. Staff was rather nonchalant in that they dismissed the problem due to age of plane. It would have been nice to know this up front so I could have come prepared to read or download movies before boarding Coincidentally or not, there was a similar issue with the entertainment system on my previous flight I took on my fist leg of the trip. There are no seat TVs, so you must rely on the app when it works. United can do better. Also, what use it it to pay for boarding group 2 when half of the passengers are in the same line as you?

Premium Plus is a really good idea for longer flights

Stuck on tarmac for two hours plus a 5.5 hour flight. Rude flight attendant. And no meals, not even for purchase!

I learned that seating towards the end of plane that a line forms for the restroom and people use your chair as a hand railing, bumping your seat consistently. I was seated in the aisle. I think that next time if I am towards the back row I would want to sit in the middle or window seat.

It would be nice to have some low carb options in the snacks.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

The flight was on time and arrived early. The crew were friendly and helpful.

Overall experience was great. Flights were almost on time in departing and we arrived at our destination as scheduled. No issues with amenities or flight crew. Everything went well as as expected. Will fly again with American Airlines in the future!

The pilot greased the landing and the crew was fantastic.

delayed due to weather. Could not communicate with family since the wifi was broken

Horrible. Both legs of my flight were delayed more than 6 hours. No compensation, no screens on the plane, and the plane was not clean.

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

The flight was flawless and we even arrived between 20 and 25 minutes early!

Very well recently! Frontier is improving and less harrassing customer on luggages! Positive!

Good for a budget airline! It was easy to get on, staff was really nice. Can’t say anything about the food or entertainment because it wasn’t available, which is fine.

I am writing to express my disappointment with my recent Frontier Airlines flight. I was charged $99 at the gate because my bag was said to be too large, yet once onboard there was no available overhead bin space, and I was required to place the bag under the seat in front of me anyway. This made the charge feel unnecessary and unfair. Additionally, before the flight even took off, I was asked to move from the seat I paid for into a middle seat so another passenger and her cat could have my seat to themselves. I was not offered compensation or an explanation for being moved from a paid seat. Between the unexpected bag fee and being forced to give up my seat, this experience fell well below acceptable customer service standards. I would appreciate a review of this situation and appropriate compensation.

It was costly and difficult to check in. $85 to take a small suitcase with me, carry on or checked and $75 on the return trip, Plus $25 if I didn't check my self in check in $25, because I couldn't do it on the kiosk. Small very uncomfortable seats, waited on the runway for near an hour each way. It was my worst flight to date.

It was ok. It was expensive to check 2 bags ($75.00 per bag), and then it took a long time to wait for shuttle to take us from one terminal to the terminal where the plane was taking off at LAX. And all of this for a flight where we had to pay for any food or drink that was not water.

It didn’t happen. I booked it and then was told it wasn’t available and then forced to pay far higher prices for a worse option

When I wanted to check in 3 hours prior to boarding time, the employees mentioned “a little over an hour delay” so I waited for an hour then I went to go look for food in the terminal and most people from that flight were in the same area looking for food. Finally I decided after food to check to see if it’s anytime closer and now it’s 2 mins until boarding closes?! What are you kidding me? I didn’t receive anything via sms about boarding now nor via email or on the intercom. I luckily made it through, barely, and then there’s no room for my carry on mind you I’m in the very first row so I had to place my purse in one further row back and my carry on sections down. Not sure who pays for better seats to get your stuff placed all over the plane but that was the worst experience I’ve ever had flying with anyone.

This airline sucks. They offer low rates then charge you for everything, the app does not work well, the seats are the most uncomfortable. Maintenance issues on the flight, and you still have to sit through their credit card commercials. People are nice enough but does not make up for overall poor experience.

Cancelled flight after I arrived at airport after 75 min drive and parking. Next flight was 4 days in the future. Had to scramble and buy a much more expensive flight on another carrier.

I liked the turn-style feature at gate 209B at LAX. Very efficient process. The gate staff also made several, clearly directed announcements so I felt very informed.

Everything you need to know for your flight from San Francisco to Knoxville

Information on your arrival and departure airports