SFO - TYS

$127 Find Cheap Flights from San Francisco to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Knoxville departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Knoxville, as well as popular online travel agencies
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Cheap Flights from San Francisco to Knoxville (SFO-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Knoxville

Sat, Oct 4 - Thu, Oct 9
Frontier Logo
10:49 am - 4:18 pmSFO-TYS
26h 29m1 stop
Frontier Logo
8:22 pm - 7:46 amTYS-SFO
14h 24m1 stop
$265Frontier
Find Deal
Mon, Sep 1 - Thu, Sep 11
Frontier Logo
6:26 am - 6:25 pmSFO-TYS
8h 59m1 stop
Frontier Logo
8:40 pm - 12:16 amTYS-SFO
6h 36m1 stop
$278Frontier
Find Deal
Fri, Sep 26 - Sat, Sep 27
United Airlines Logo
10:45 pm - 10:29 amSFO-TYS
8h 44m1 stop
United Airlines Logo
4:40 pm - 8:54 pmTYS-SFO
7h 14m1 stop
$304United Airlines
Find Deal
Sun, Sep 28 - Tue, Oct 7
American Airlines Logo
6:00 am - 5:36 pmSFO-TYS
8h 36m1 stop
American Airlines Logo
12:35 pm - 5:18 pmTYS-SFO
7h 43m1 stop
$309American Airlines
Find Deal
Wed, Aug 13 - Sat, Aug 23
Delta Logo
6:15 am - 3:34 pmSFO-TYS
6h 19m1 stop
Delta Logo
7:50 am - 2:27 pmTYS-SFO
9h 37m1 stop
$339Delta
Find Deal
Thu, Nov 6 - Tue, Nov 11
United Airlines Logo
11:44 pm - 10:05 amSFO-TYS
7h 21m1 stop
United Airlines Logo
7:00 am - 12:10 pmTYS-SFO
8h 10m1 stop
$363United Airlines
Find Deal
Sun, Sep 28 - Tue, Oct 7
Delta Logo
10:50 pm - 10:56 amSFO-TYS
9h 06m1 stop
Delta Logo
3:48 pm - 11:33 pmTYS-SFO
10h 45m2 stops
$367Delta
Find Deal
Thu, Nov 6 - Tue, Nov 11
American Airlines Logo
6:00 am - 3:37 pmSFO-TYS
6h 37m1 stop
American Airlines Logo
4:27 pm - 11:09 pmTYS-SFO
9h 42m1 stop
$383American Airlines
Find Deal
Sun, Aug 10 - Wed, Aug 20
 Logo
11:59 pm - 4:12 pmSFO-TYS
13h 13m1 stop
 Logo
10:54 am - 5:12 pmTYS-SFO
33h 18m3 stops
Thu, Nov 6 - Mon, Nov 10
 Logo
6:18 pm - 10:26 pmSFO-TYS
25h 08m2 stops
 Logo
7:20 am - 5:18 pmTYS-SFO
12h 58m2 stops
Booking Insights

KAYAK's insights & trends for San Francisco to Knoxville flights

Get data-powered insights and trends into flights from San Francisco to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from San Francisco to Knoxville?

The average price of all round-trip flights from San Francisco to Knoxville clicked on KAYAK for each day over the last 12 months.

When flying from San Francisco to Knoxville, you should consider leaving on a Tuesday and avoid Fridays if you are looking for the best rates. For your return to San Francisco, you’ll find the best rates on Tuesdays and the most expensive ones on Mondays.

What is the cheapest month to fly from San Francisco to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Knoxville is August, where tickets cost $406 (return) on average. On the other hand, the most expensive months are December and June, where the average cost of round-trip tickets is $588 and $538 respectively.

How far in advance should I book a flight from San Francisco to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Knoxville, you should book around 3 weeks before departure, which saves you about 18% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 19 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$127
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 11% increase in price.
Flight from San Francisco to Knoxville

When to book flights from San Francisco to Knoxville

Are your dates flexible? Find out the best times to travel from San Francisco to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Francisco to Knoxville

  • What are the transportation options to get from the McGhee Tyson Airport (TYS) to downtown Knoxville?

    Since there are no public transportation options that offer service from the airport to the downtown area, the best choice for most travelers is to take one of the readily available taxis outside of the terminal building that will make the trip in about 18min.

  • Where should I be looking for my rental car company when I arrive at the airport in Knoxville?

    There are roughly 8 different rental car companies that operate at this airport, and every one of them has a customer service counter on the lower level of the airport terminal building adjacent to the baggage claim area. All vehicles for rent sit just outside of the exit doors from the baggage claim area in the adjacent parking lots.

  • Where should I plan on meeting my rideshare ride after my flight to Knoxville?

    All rideshare companies do their pick-ups on the lower level of the terminal building just outside of the baggage claim area. When you exit the baggage claim area of the terminal building, you will see signage for pick-up locations just to the right.

  • Are there any hotels that have a convenient location close to the terminal buildings at the airport in Knoxville?

    One of the most convenient choices is Hilton Knoxville Airport, which has a location right on the airport property. When you walk out of the terminal building, you will see this hotel just a few steps from the terminal building to your right just before the Economy Parking Lot B.

  • What is the cheapest flight from San Francisco to Knoxville?

    In the last 3 days, the lowest price for a flight from San Francisco to Knoxville was $127 for a one-way ticket and $265 for a round-trip.

  • Do I need a passport to fly between San Francisco and Knoxville?

    No

  • Which airports will I be using when flying from San Francisco to Knoxville?

    San Francisco airport is called San Francisco and the only airport in Knoxville is Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from San Francisco to Knoxville?

    The Embraer 175 is the aircraft model that flies most regularly on the San Francisco to Knoxville flight route.

  • Which airline alliances offer flights from San Francisco to Knoxville?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between San Francisco and Knoxville, with SkyTeam being the most commonly used for this route.

  • What is the most popular layover when flying to Knoxville from San Francisco?

    Dallas is the most popular layover city among KAYAK users traveling from San Francisco to Knoxville.

  • Which is the best airline for flights from San Francisco to Knoxville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from San Francisco to Knoxville are Delta and United Airlines. With an average price for the route of $435 and an overall rating of 8.0, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $573 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from San Francisco to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to San Francisco with another airline. Booking your flights between San Francisco and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from San Francisco to Knoxville

  • A fantastic way to get to the San Francisco International Airport (SFO) from the downtown area without having to drive your own car is to take the BART Yellow Line light rail train that can make the trip from the downtown area to the airport in 29 minutes.
  • If you plan on getting dropped off at the San Francisco International Airport before your flight, a good choice for a drop-off point is the Kiss and Fly location adjacent to the rental car center at the airport. This allows passengers to take their time getting dropped off, and then they can ride aboard the AirTrain Blue Line to the terminal building from the rental car center.
  • Parents who plan on taking their kids through the San Francisco International Airport before a flight to Knoxville should know that the airport offers an interactive play area in terminal two that lets kids have some fun and expend some energy before a long flight.
  • Travelers making their way to Knoxville with a pet or a service animal should know that the San Francisco International Airport offers seven different pet relief areas both outside and inside the terminal buildings at the airport. All of the relief areas have things like drinking bowls and waste gloves with disposal areas.
  • If you plan on flying to Knoxville from the San Francisco International Airport and want a comfortable place to wait for your flight, the San Francisco International Airport offers airline lounges from United Airlines, Alaska Airlines, Delta Airlines, and American Airlines that all offer plenty of comfortable seating options as well as a wide selection of food and beverage choices.

Reviews of the top 4 airlines serving from San Francisco to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7981 reviews
8.5Crew
7.9Entertainment
7.3Food
7.9Comfort
8.2Boarding
Airline reviews

My husband upgraded our seats and I don't know if it was due to the type of planet was or if they didn't upgrade our seats. We were supposed to be in I believe comfort seats and they were just as tight as any other seat- no leg room and we are very tall people but at least it wasn't extremely cold. My husband did put in a complaint about our seating because he paid extra and if we would have known that the space and the tightness would have been the same, we just would have gotten the emergency row emergency row seats that we normally get. We love Delta but both our flights coming home we're not good. Oh I forgot to mention that on our flight to Hawaii our luggage wheels got broke and we had to purse new luggage on vacation then we never had this problem so we didn't know protocol and reported it after we got home only for them to tell is we only had 24hrs to report the damage. Not sure what was going on with Delta this vacation trip.

4.0 OkayMrs., Jul 2025LAX - RDU
Read more Delta reviews

My husband upgraded our seats and I don't know if it was due to the type of planet was or if they didn't upgrade our seats. We were supposed to be in I believe comfort seats and they were just as tight as any other seat- no leg room and we are very tall people but at least it wasn't extremely cold. My husband did put in a complaint about our seating because he paid extra and if we would have known that the space and the tightness would have been the same, we just would have gotten the emergency row emergency row seats that we normally get. We love Delta but both our flights coming home we're not good. Oh I forgot to mention that on our flight to Hawaii our luggage wheels got broke and we had to purse new luggage on vacation then we never had this problem so we didn't know protocol and reported it after we got home only for them to tell is we only had 24hrs to report the damage. Not sure what was going on with Delta this vacation trip.

Crew was excellent. Comfort seats not as nice as other kinds of planes.

It was a great flight and the stewards and stewardess were all kind and accommodating!! The seats were comfortable and entertainment screen excellent!

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

There was a security issue at the airport and we were unable to land. We circled endlessly and then landed at another airfield for fuel. We then circled the airport again, almost landed but didn’t fully touch down before circling again. I am thankful to the crew for keeping us safe- the issue was the airline and staff at the airport getting us seats on our connecting flights. That part was hours of searching for someone and getting in double my steps.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

737-800 in first class was pretty dumpy. Seat had an uncomfortable angle, storage under the seat was blocked so even my very modest backpack didn't fit, power outlet was flaky. Weird tiny seat pockets that couldn't hold a gallon ziploc bag, emesis bag missing, etc. etc. No in-flight service due to turbulence. Crew was excellent, boarding was smooth despite a full flight.

Delta flight was on time, seats were comfortable, and crew was nice.

I learned that seating towards the end of plane that a line forms for the restroom and people use your chair as a hand railing, bumping your seat consistently. I was seated in the aisle. I think that next time if I am towards the back row I would want to sit in the middle or window seat.

The best airline I have ever travel , really good customer service, attention and service !!

Everything was great. Only thing that could’ve made it better was buy on board options for hot food, but the snacks were decent. The flight attendants were great. I had no complaints. I was able to make it to my destination safely

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

Very comfortable (upgraded to business class). The audio on my screen didn’t work, but I managed to play the audio through my phone while watching the screen.

Boarding seemed to be organized bedlam. For what ever reason, preboarding took longer than 20 minutes. Made the plane 20 minutes late taking off. Luckily we arrived on time. Flight crew seemed very friendly. Only slight turbulence.

The personnel were professional and friendly. The Boeing 737 Max 9 is too claustrophobic and was very warm at both airport gates, and still warm in the air.

While the staff was pleasant and helpful, the following observations are for your awareness. There was some delay on the tarmac on take off and landing. The paid lunch/food offerings were limited. Entertainment was only available on WiFi at a cost.

get E+, a must for 5 hours flight if you are tall

Compared with other carriers business class for an overnight was not worth the extra expense.

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Delayed flight, so I switched fights to SFO to Phoenix , Phoenix to DSM. Excellent service through American Airlines

AA re-routed flight from HNL to LAX due to delay. My group of 3 with reserved seats in row 9 was broken up, with one assigned to a middle seat, another in the last row of the plane. Not happy. No explanation to the delay. No apologies. No compensation. Would have been nice to be offered an Admiral Club admission or a voucher for the extra 3 hours of layover in LAX. Could not hear the boarding gate announcements in LAX. Adjacent gate was boarding at the same time. Loud speakers were competing against each other. Barely made my boarding group.

Almost a 6 hour flight and the only food option is a cheese plate… and chips. Also how is it there are no options for texting on American. I’ll be going back to delta and united.

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

The chair cushions may need an upgrade. I have been noticing they are so worn out, thin so you’d sit in a dip 😄. Other than that, all was an enjoyable trip. Thanks AA!

Cramped seats. FAA should make airlines have more legroom, for even short people complain

Eventless. It was a good flight and good crew. Can’t complaint.

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

British Airways staff are very polite and willing to help.

Severe turbulence. Captain never came on to reassure passengers after things settled down.

My first flight was delayed 5 hours. The 2nd flight was canceled til the next day and the never even tried to compensate for it. Worse I was delayed again on the flight the rebooked me on.

Cancelled flight after I arrived at airport after 75 min drive and parking. Next flight was 4 days in the future. Had to scramble and buy a much more expensive flight on another carrier.

I liked the turn-style feature at gate 209B at LAX. Very efficient process. The gate staff also made several, clearly directed announcements so I felt very informed.

The seats were awful, hard plastic covered in sheet vinyl. The airline tries to scam you into paying extra to get seat together when the flight wasn’t full. They were going to separate a family with young children but my wife who had a row to herself gave up her seat so the young mom could be with her young boys. I’m never giving this airline my money again.

It was a short flight so no food or entertainment….

Frontier had yet another flight cancellation. Have never made a complete round trip with this airline without at least one leg getting cancelled. Miserable flights - dirty, uncomfortable planes that apparently always have issues since I've had multiple delays and cancellations with them.

Flight was delayed 3 times, would have been nice to have received text message instead of email notifications. Frontier app wasn’t even updated accordingly, no gate number disclosed. No agent at front desk of gate to inform of delay. Very confused and left if the dark

They changed the timing , first delayed by 4 hours then went back to 40 mins late, we had to run back to airport to not miss our flight. This is ridiculous

No frills for sure. No gate announcements about flight delay, not even water to drink on the flight.

Everything you need to know for your flight from San Francisco to Knoxville

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