SFO - TYS

$129 Find Cheap Flights from San Francisco to Knoxville - Compare and Save

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Everything you should know

Cheapest round-trip
$250
Typical prices: $405-$618
Southwest
Fri 1/26Tue 2/6
SFO - TYS • 1 stop
Cheapest one-way
$125
Typical prices: $219-$383
Southwest
Fri 1/26
SFO - TYS • 1 stop
Nonstop flights
There are currently no direct flights between San Francisco and Knoxville. You'll need to take a connecting flight to reach the destination.
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When to book
in advance
Our data shows that travelers who book at least 22 weeks in advance save around 44% compared to booking last minute.
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Insights
When to travel
Cheapest • 26% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $407 (round-trip)
Shortest trip • 7h 27m (one-way)
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Flight Deals

Cheap Flights from San Francisco to Knoxville (SFO-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Knoxville

Tue, Jan 26 - Sat, Feb 6
Southwest Logo
6:35 am - 3:45 pmSFO  San Francisco-TYS Knoxville McGhee Tyson
6h 10m1 stop Denver Intl
Southwest Logo
4:20 pm - 8:25 pmTYS  Knoxville McGhee Tyson-SFO San Francisco
7h 05m1 stop Denver Intl
$250Southwest
Sat, Oct 17 - Wed, Oct 21
American Airlines Logo
5:00 am - 5:36 pmSFO  San Francisco-TYS Knoxville McGhee Tyson
9h 36m1 stop Charlotte Douglas
American Airlines Logo
6:56 am - 12:27 pmTYS  Knoxville McGhee Tyson-SFO San Francisco
8h 31m1 stop Charlotte Douglas
$257American Airlines
Tue, Oct 20 - Sat, Oct 24
Delta Logo
11:30 pm - 9:34 amSFO  San Francisco-TYS Knoxville McGhee Tyson
7h 04m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 10:26 amTYS  Knoxville McGhee Tyson-SFO San Francisco
7h 46m1 stop Atlanta Hartsfield-Jackson
$257Delta
Wed, Oct 28 - Sat, Oct 31
Delta Logo
8:00 am - 5:28 pmSFO  San Francisco-TYS Knoxville McGhee Tyson
6h 28m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:26 am - 2:20 pmTYS  Knoxville McGhee Tyson-SFO San Francisco
9h 54m1 stop Detroit Metropolitan Wayne County
$257Delta
Tue, Jan 19 - Sat, Jan 30
American Airlines Logo
11:12 am - 11:11 pmSFO  San Francisco-TYS Knoxville McGhee Tyson
8h 59m1 stop Dallas/Fort Worth
American Airlines Logo
12:26 pm - 7:32 pmTYS  Knoxville McGhee Tyson-SFO San Francisco
10h 06m1 stop Dallas/Fort Worth
$257American Airlines
Tue, Jan 26 - Sat, Feb 6
Southwest Logo
6:35 am - 3:45 pmSFO  San Francisco-TYS Knoxville McGhee Tyson
6h 10m1 stop Denver Intl
Southwest Logo
6:55 am - 4:45 pmTYS  Knoxville McGhee Tyson-SFO San Francisco
12h 50m2 stops Nashville Intl Los Angeles
$261Southwest
Wed, Oct 28 - Thu, Nov 5
Multiple Airlines Logo
3:05 pm - 8:39 pmSFO  San Francisco-TYS Knoxville McGhee Tyson
26h 34m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
9:33 pm - 12:52 pmTYS  Knoxville McGhee Tyson-SFO San Francisco
18h 19m1 stop Las Vegas Harry Reid Intl
$263Multiple Airlines
Mon, Oct 5 - Wed, Oct 7
United Airlines Logo
11:30 pm - 9:45 amSFO  San Francisco-TYS Knoxville McGhee Tyson
7h 15m1 stop Chicago O'Hare Intl
United Airlines Logo
7:25 pm - 12:59 amTYS  Knoxville McGhee Tyson-SFO San Francisco
8h 34m1 stop Washington, D.C. Dulles Intl
$270United Airlines
Thu, Oct 29 - Mon, Nov 2
American Airlines Logo
1:27 pm - 11:55 pmSFO  San Francisco-TYS Knoxville McGhee Tyson
7h 28m1 stop Charlotte Douglas
American Airlines Logo
5:32 pm - 12:39 amTYS  Knoxville McGhee Tyson-SFO San Francisco
10h 07m1 stop Dallas/Fort Worth
$283American Airlines
Fri, Oct 16 - Sat, Oct 17
United Airlines Logo
12:35 am - 1:14 pmSFO  San Francisco-TYS Knoxville McGhee Tyson
9h 39m1 stop Chicago O'Hare Intl
United Airlines Logo
6:03 pm - 12:30 amTYS  Knoxville McGhee Tyson-SFO San Francisco
9h 27m1 stop Chicago O'Hare Intl
$332United Airlines
Booking Insights

Price, demand and travel trends for San Francisco to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from San Francisco to Knoxville with more confidence.

How much is a round-trip flight from San Francisco to Knoxville?

Round-trip flights from San Francisco to Knoxville start at $250. Prices are below average for this route right now, with typical round-trip fares ranging from $405 to $618. The lowest price found in the past 5 days was $250 on Southwest.

What's the cheapest day of the week to fly from San Francisco to Knoxville?

Monday is the cheapest day of the week to fly from San Francisco to Knoxville, it is 20% cheaper than the average day. Sunday is the most expensive day with flight prices 24% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from San Francisco to Knoxville?

•February is the cheapest month to fly from San Francisco to Knoxville at $379 round-trip.
•May ($594) and November ($574) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 56% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from San Francisco to Knoxville the cheapest?

Flights from San Francisco to Knoxville are cheapest 22 weeks before departure. Booking in this window typically costs about 44% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Key details for San Francisco to Knoxville flights

Low season

September

Cheapest flight

$125
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from San Francisco to Knoxville

When to book flights from San Francisco to Knoxville

Are your dates flexible? Find out the best times to travel from San Francisco to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your San Francisco to Knoxville flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • What are the transportation options to get from the McGhee Tyson Airport (TYS) to downtown Knoxville?

    Since there are no public transportation options that offer service from the airport to the downtown area, the best choice for most travelers is to take one of the readily available taxis outside of the terminal building that will make the trip in about 18min.

  • Where should I be looking for my rental car company when I arrive at the airport in Knoxville?

    There are roughly 8 different rental car companies that operate at this airport, and every one of them has a customer service counter on the lower level of the airport terminal building adjacent to the baggage claim area. All vehicles for rent sit just outside of the exit doors from the baggage claim area in the adjacent parking lots.

  • Where should I plan on meeting my rideshare ride after my flight to Knoxville?

    All rideshare companies do their pick-ups on the lower level of the terminal building just outside of the baggage claim area. When you exit the baggage claim area of the terminal building, you will see signage for pick-up locations just to the right.

  • Are there any hotels that have a convenient location close to the terminal buildings at the airport in Knoxville?

    One of the most convenient choices is Hilton Knoxville Airport, which has a location right on the airport property. When you walk out of the terminal building, you will see this hotel just a few steps from the terminal building to your right just before the Economy Parking Lot B.

  • Which airports can I use when flying from San Francisco to Knoxville?

    Flights from San Francisco to Knoxville usually depart from San Francisco (SFO) and arrive at Knoxville McGhee Tyson (TYS).

  • What cabin classes can I book on flights from San Francisco to Knoxville?

    Three cabin classes are available on flights from San Francisco to Knoxville:

    • Economy Class
    • Premium Economy Class
    • First Class

  • Which airports do connecting flights from San Francisco to Knoxville pass through?

    One-stop flights from San Francisco to Knoxville most commonly connect through:

    • Dallas/Fort Worth (DFW) - 50% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 18% of one-stop connections
    • Denver Intl (DEN) - 11% of one-stop connections
    • Charlotte Douglas (CLT) - 7% of one-stop connections

    Dallas/Fort Worth (DFW) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from San Francisco to Knoxville?

    Yes. Being flexible with your travel dates can save you up to 35% on the San Francisco to Knoxville route. Monday is the cheapest departure day at $412 round-trip on average, while Sunday is the most expensive at $632, a difference of $220. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How expensive are last-minute San Francisco to Knoxville flights?

    Last-minute fares on this route - booked within 2 weeks of departure - run 16% above the route average of $509. Book 22 weeks before departure for the lowest fares.

  • How long is a flight from San Francisco to Knoxville?

    A nonstop flight from San Francisco to Knoxville takes 0h 00m, covering 2,114 miles.

  • Do I need a passport to fly from San Francisco to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • How are flight prices from San Francisco to Knoxville looking right now?

    One-way fares from San Francisco to Knoxville are currently lower than usual. Average one-way flight prices are about $149, which is 50% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from San Francisco to Knoxville?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 7h 27m, compared with 7h 29m via Dallas/Fort Worth (DFW) and 7h 48m via Chicago O'Hare Intl (ORD).

  • What is the time difference between San Francisco and Knoxville?

    Knoxville is 3 hours ahead of San Francisco (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    • Budget
    • Alamo
    • Thrifty
    • Enterprise Rent-A-Car
    • Payless

  • How much should I expect to pay for a San Francisco to Knoxville flight?

    Round-trip flights from San Francisco to Knoxville range from $405 to $618, with an average of $509 over the past 12 months. Anything below $405 counts as a good deal.

Your guide to booking San Francisco to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Monday departure instead of Sunday. On this route, Monday flights average $412 - about $220 less than Sunday (35% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 22 weeks before you fly. On this route, that window historically saves about 44% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your San Francisco to Knoxville trip for February. Fares historically average $379 round-trip in that month - typically $215 less than the most expensive month, which is May (based on the last 12 months).
  • A fantastic way to get to the San Francisco International Airport (SFO) from the downtown area without having to drive your own car is to take the BART Yellow Line light rail train that can make the trip from the downtown area to the airport in 29 minutes.
  • If you plan on getting dropped off at the San Francisco International Airport before your flight, a good choice for a drop-off point is the Kiss and Fly location adjacent to the rental car center at the airport. This allows passengers to take their time getting dropped off, and then they can ride aboard the AirTrain Blue Line to the terminal building from the rental car center.
  • Parents who plan on taking their kids through the San Francisco International Airport before a flight to Knoxville should know that the airport offers an interactive play area in terminal two that lets kids have some fun and expend some energy before a long flight.
  • Travelers making their way to Knoxville with a pet or a service animal should know that the San Francisco International Airport offers seven different pet relief areas both outside and inside the terminal buildings at the airport. All of the relief areas have things like drinking bowls and waste gloves with disposal areas.
  • If you plan on flying to Knoxville from the San Francisco International Airport and want a comfortable place to wait for your flight, the San Francisco International Airport offers airline lounges from United Airlines, Alaska Airlines, Delta Airlines, and American Airlines that all offer plenty of comfortable seating options as well as a wide selection of food and beverage choices.

More options for your flight from San Francisco to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental