TYS - SYR

$132 Find Cheap Flights from Knoxville to Syracuse - Compare and Save

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Everything you should know

Cheapest round-trip
$303
Typical prices: $288-$413
American Airlines
Sun 10/7Sun 10/14
TYS - SYR • 1 stop
Cheapest one-way
$139
Typical prices: $283-$449
Allegiant Air
Wed 10/10
TYS - SYR • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Syracuse. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
December
Cheapest • 29% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
New York LaGuardia (LGA)
Cheapest • Avg $320 (round-trip)
Washington, D.C. Dulles Intl (IAD)
Shortest trip • 4h 23m (one-way)
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Insights
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Flight Deals

Cheap Flights from Knoxville to Syracuse (TYS-SYR)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Syracuse

Wed, Oct 7 - Wed, Oct 14
American Airlines Logo
6:05 pm - 11:59 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
5h 54m1 stop Washington, D.C. Reagan-National
American Airlines Logo
6:00 am - 10:25 amSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
4h 25m1 stop Washington, D.C. Reagan-National
$303American Airlines
Wed, Oct 14 - Sun, Oct 18
Delta Logo
5:15 pm - 10:57 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
5h 42m1 stop New York LaGuardia
Delta Logo
6:22 am - 10:20 amSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
3h 58m1 stop Detroit Metropolitan Wayne County
$303Delta
Wed, Oct 7 - Wed, Oct 14
United Airlines Logo
6:00 am - 2:19 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
8h 19m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
United Airlines Logo
6:00 am - 10:37 amSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
4h 37m1 stop Washington, D.C. Dulles Intl
$308United Airlines
Thu, Oct 15 - Mon, Oct 19
Delta Logo
5:18 pm - 11:18 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
6h 00m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:08 am - 11:02 amSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
4h 54m1 stop New York LaGuardia
$319Delta
Fri, Oct 16 - Sun, Oct 18
Delta Logo
5:02 pm - 10:57 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
5h 55m1 stop New York LaGuardia
Delta Logo
6:22 am - 10:20 amSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
3h 58m1 stop Detroit Metropolitan Wayne County
$319Delta
Sat, Oct 10 - Sat, Oct 17
American Airlines Logo
6:06 pm - 10:40 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
4h 34m1 stop Charlotte Douglas
American Airlines Logo
7:43 pm - 11:55 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
4h 12m1 stop Charlotte Douglas
$323American Airlines
Fri, Nov 6 - Sun, Nov 8
American Airlines Logo
7:50 am - 2:44 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
6h 54m1 stop Philadelphia
American Airlines Logo
6:02 am - 10:30 amSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
4h 28m1 stop Charlotte Douglas
$339American Airlines
Thu, Oct 15 - Mon, Oct 19
American Airlines Logo
10:00 am - 3:38 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
5h 38m1 stop Charlotte Douglas
American Airlines Logo
5:36 pm - 9:33 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
3h 57m1 stop Washington, D.C. Reagan-National
$339American Airlines
Sat, Oct 17 - Sun, Oct 18
Allegiant Air Logo
4:41 pm - 9:28 amTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
16h 47m1 stop Fort Lauderdale
Allegiant Air Logo
9:45 pm - 9:39 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
23h 54m2 stops Nashville Intl Orlando Sanford Intl
$385Allegiant Air
Sat, Oct 24 - Sat, Oct 31
United Airlines Logo
6:00 am - 11:53 amTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
5h 53m1 stop Chicago O'Hare Intl
United Airlines Logo
6:00 am - 1:13 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
7h 13m1 stop Chicago O'Hare Intl
$387United Airlines
Booking Insights

Price, demand and travel trends for Knoxville to Syracuse flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Knoxville to Syracuse with more confidence.

How much is a round-trip flight from Knoxville to Syracuse?

Round-trip flights from Knoxville to Syracuse start at $303. Prices are typical for this route right now, with typical round-trip fares ranging from $288 to $413. The lowest price found in the past 5 days was $303 on American Airlines.

What is the cheapest month to fly from Knoxville to Syracuse?

  • December is the cheapest month to fly from Knoxville to Syracuse at $248 round-trip.
  • February ($583) and January ($419) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 135% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Knoxville to Syracuse flights

Low season

January

Cheapest flight

$139
Best time to beat the crowds but there is an average 20% increase in price.
Most popular time to fly with an average 4% increase in price.
Flight from Knoxville to Syracuse

When to book flights from Knoxville to Syracuse

Are your dates flexible? Find out the best times to travel from Knoxville to Syracuse based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Syracuse flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Knoxville to Syracuse?

    Flights from Knoxville to Syracuse usually depart from Knoxville McGhee Tyson (TYS) and arrive at Syracuse Hancock Intl (SYR).

  • What cabin classes can I book on flights from Knoxville to Syracuse?

    Two cabin classes are available on flights from Knoxville to Syracuse:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Knoxville to Syracuse pass through?

    One-stop flights from Knoxville to Syracuse most commonly connect through:

    • Charlotte Douglas (CLT) - 26% of one-stop connections
    • Washington, D.C. Dulles Intl (IAD) - 18% of one-stop connections
    • Washington, D.C. Reagan-National (DCA) - 13% of one-stop connections
    • Philadelphia (PHL) - 13% of one-stop connections

    Charlotte Douglas (CLT) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Knoxville to Syracuse?

    Yes. Being flexible with your travel dates can save you up to 38% on the Knoxville to Syracuse route. Tuesday is the cheapest departure day at $293 round-trip on average, while Sunday is the most expensive at $472, a difference of $179. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How long is a flight from Knoxville to Syracuse?

    A nonstop flight from Knoxville to Syracuse takes 0h 00m, covering 656 miles.

  • Do I need a passport to fly from Knoxville to Syracuse?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Knoxville to Syracuse changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $319 to $1,615. That means the highest observed fare was about 5x higher than the lowest one.

  • How are flight prices from Knoxville to Syracuse looking right now?

    One-way fares from Knoxville to Syracuse are currently lower than usual. Average one-way flight prices are about $254, which is 31% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Knoxville to Syracuse?

    Flying via Washington, D.C. Dulles Intl (IAD) gives the shortest average 1-stop total travel time at 4h 23m, compared with 4h 32m via Philadelphia (PHL) and 4h 36m via Charlotte Douglas (CLT).

  • What car rental options are available at Syracuse Hancock Intl Airport (SYR)?

    Syracuse Hancock Intl Airport (SYR) hosts 5 major car rental companies, with daily rates starting from around $29 for economy cars. Top options include:
    • Hertz
    • Dollar
    • Budget
    • Alamo
    • Avis

  • How much should I expect to pay for a Knoxville to Syracuse flight?

    Round-trip flights from Knoxville to Syracuse range from $288 to $413, with an average of $350 over the past 12 months. Anything below $288 counts as a good deal.

Your guide to booking Knoxville to Syracuse flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Tuesday departure instead of Sunday. On this route, Tuesday flights average $293 - about $179 less than Sunday (38% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Knoxville to Syracuse trip for December. Fares historically average $248 round-trip in that month - typically $335 less than the most expensive month, which is February (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Syracuse Hancock Intl Airport.
    - Livaway Suites Syracuse
    - DoubleTree by Hilton Hotel Syracuse
    - Comfort Inn and Suites Syracuse-Carrier Circle

More options for your flight from Knoxville to Syracuse

Complete your trip to Syracuse with a hotel stay or car rental

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