TYS - SYR

$157 Find Cheap Flights from Knoxville to Syracuse - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Syracuse departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$287
Typical prices: $301-$483
Delta
Wed 8/26Wed 9/2
TYS - SYR • 1 stop
Cheapest one-way
$157
Allegiant Air
Sun 10/18
TYS - SYR • 1 stop
Top airlines
Cheapest • from $287 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Syracuse. You'll need at least 1 connection.
Insights
Insights
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Insights
Top layover airports
Cheapest • Avg $320 (round-trip)
Shortest trip • 4h 21m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 33% price drop
Most popular
Good to know
Good to know
+1
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Good to know
Good to know
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Syracuse (TYS-SYR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Syracuse that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Syracuse

Wed, Aug 26 - Wed, Sep 2
Delta Logo
11:38 am - 4:40 pm
TYS
-
SYR
5h 02m
1 stop
Delta Logo
6:10 am - 1:34 pm
SYR
-
TYS
7h 24m
1 stop
$287Delta
Sat, Oct 3 - Sun, Oct 11
Multiple Airlines Logo
6:43 pm - 7:02 pm
TYS
-
SYR
24h 19m
1 stop
Multiple Airlines Logo
10:58 am - 9:31 pm
SYR
-
TYS
34h 33m
2 stops
$288Multiple Airlines
Thu, Oct 1 - Sun, Oct 4
Allegiant Air Logo
8:44 pm - 8:50 am
TYS
-
SYR
12h 06m
1 stop
Allegiant Air Logo
11:28 am - 10:35 am
SYR
-
TYS
23h 07m
1 stop
$298Allegiant Air
Sat, Oct 3 - Sun, Oct 11
Multiple Airlines Logo
6:43 pm - 7:02 pm
TYS
-
SYR
24h 19m
1 stop
Multiple Airlines Logo
10:58 am - 9:31 pm
SYR
-
TYS
34h 33m
2 stops
$300Multiple Airlines
Fri, Sep 11 - Sun, Sep 13
American Airlines Logo
4:46 pm - 11:36 pm
TYS
-
SYR
6h 50m
1 stop
American Airlines Logo
7:44 pm - 11:51 pm
SYR
-
TYS
4h 07m
1 stop
$303American Airlines
Sat, Aug 29 - Thu, Sep 3
American Airlines Logo
6:41 pm - 11:45 pm
TYS
-
SYR
5h 04m
1 stop
American Airlines Logo
5:17 pm - 10:58 pm
SYR
-
TYS
5h 41m
1 stop
$303American Airlines
Sat, Oct 3 - Sun, Oct 11
Delta Logo
1:40 pm - 9:01 pm
TYS
-
SYR
7h 21m
1 stop
Delta Logo
6:00 am - 10:54 am
SYR
-
TYS
4h 54m
1 stop
$303Delta
Wed, Oct 14 - Sun, Oct 18
Delta Logo
6:00 am - 11:27 am
TYS
-
SYR
5h 27m
1 stop
Delta Logo
6:08 am - 11:16 am
SYR
-
TYS
5h 08m
1 stop
$303Delta
Fri, Sep 11 - Fri, Sep 18
Delta Logo
5:45 pm - 11:58 pm
TYS
-
SYR
6h 13m
1 stop
Delta Logo
6:54 pm - 11:55 pm
SYR
-
TYS
5h 01m
1 stop
$303Delta
Thu, Oct 15 - Mon, Oct 19
American Airlines Logo
6:00 am - 10:24 am
TYS
-
SYR
4h 24m
1 stop
American Airlines Logo
7:43 pm - 11:55 pm
SYR
-
TYS
4h 12m
1 stop
$319American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Syracuse flights

Get data-powered insights and trends into flights from Knoxville to Syracuse to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to Syracuse?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Syracuse departing in August.

Flight prices are below average for this route right now.

Flights to Syracuse from Knoxville usually cost between $308 and $407 in August.
The lowest price found in the past 5 days was $287 on Delta (Aug 26-Sep 2).

What is the cheapest month to fly from Knoxville to Syracuse?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Syracuse, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Syracuse is December, where tickets cost $248 (return) on average. On the other hand, the most expensive months are February and January, where the average cost of round-trip tickets is $583 and $419 respectively.

Good to know

Low season

January

Cheapest flight

$157
Best time to beat the crowds but there is an average 13% increase in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Knoxville to Syracuse

When to book flights from Knoxville to Syracuse

Are your dates flexible? Find out the best times to travel from Knoxville to Syracuse based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Syracuse

  • What is the cheapest flight from Knoxville to Syracuse?

    In the last 5 days, the lowest price for a flight from Knoxville to Syracuse was $157 for a one-way ticket and $287 for a round-trip.

  • Do I need a passport to fly between Knoxville and Syracuse?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Knoxville to Syracuse?

    Knoxville and Syracuse are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Syracuse Hancock Intl.

  • Which aircraft models fly most regularly from Knoxville to Syracuse?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Syracuse?

    SkyTeam, and oneworld are the airline alliances operating flights between Knoxville and Syracuse, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Syracuse, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Syracuse are Delta and American Airlines. With an average price for the route of $343 and an overall rating of 7.8, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $338 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Knoxville to Syracuse?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Syracuse.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Syracuse?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Syracuse from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Syracuse?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Syracuse with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and SYR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Syracuse?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Syracuse from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Syracuse

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Syracuse. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Syracuse? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8487 reviews
7.2Food
8.1Boarding
7.8Comfort
8.5Crew
7.8Entertainment
Airline reviews

Flight from Savannah arrived very late and we did not take off till 2 hours after scheduled departure!

2.0 MediocreBruce, Jul 2026
BOS - LGA
Read more Delta reviews

Flight from Savannah arrived very late and we did not take off till 2 hours after scheduled departure!

My flight was canceled, and instead of rebooking me on a non-stop first-class flight for the same day, which I originally had, Delta rebooked me on a one-stop flight for the following day. When I checked the Delta app, I noticed that there were available flights for both the same day and the next day. I believe this indicates poor management on their part.

My flight home from Knoxville, TN, included a layover in Atlanta. I boarded the aircraft in Zone 5 and although there was limited overhead space, I was able to put my 'backpack' style roller-bag above my seat. Unfortunately, due to continued bad weather, we had to deplane. There were many people who would have missed their connection, so they rebooked. When we were re-boarding, the gate agent welcomed zone 5 and then made an announcement: All roller-bags for zone 5 passengers and higher will need to be gate checked. I promptly pushed the telescoping handle in and held my bag like a backpack. I was able to bring it on board, which was a relief. Upon entering the aircraft it became apparent that there was easily 40% open overhead space. There were audible signs of angry passengers who felt duped into checking their bags when in fact there were noticeably LESS passengers on the aircraft and TONS of overhead space. I'm not sure what kinds of parameters are used to determine when to cut off roller-bags from being brought on board, but it seemed deceptive and underhanded to have so many people get stuck checking their bags when clearly there was ample room for at least one more zone.

So terrible. My flight was 4 hours delayed and we weren't notified til last second within an hour of boarding. WE had to sit on the plane for 4 hours. ridiculous.

The CRJ-900 was clean but the overhead air vents were broken in our First Class row, making the cabin very hot until about 30 mins into the flight. The flight attendants were both extremely apologetic and accommodating though so that is why I rated the flight as very good. They checked on us many times and truly showed they cared. The snacks for an hour and a half flight could be better. Would be nice if there was a small plated meal over convenient store snacks. WiFi also was not working. And it would be nice if Delta had adjustable headrests on these planes.

The plane was old and thus the seats were not good. No cushion left whatsoever, and it all was a bit worn out.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

Delta does a great job with entertainment and free wifi. I can still be in touch with my colleagues while in the air.

From Atlanta to Cabo I would have hoped on a plane that size I would have been able to breathe and wiggle my feet a little! The leg room in that plane is non existent and I am only 5”4’. And the air vent either wasn’t working very well or just could not blow air from the ceiling to the seat area as I was suffocating through the entire flight! And please don’t say I would have been more comfortable in first class because I cannot afford those rates and have always travelled Main Cabin without issues !

Flight cancelled going to FLL and flight from Miami delayed 6 hours. Had to rebook or miss connection.

They cancelled our flight two times after rebooking us for a later flight. We never got on the plane. We found another solution by driving.

Not to have gotten delayed by 2+ hours for the fourth straight American flight. They're the worst.

Long delays, lack of information about the status of the flight. The flight was delayed 4 times.

Bags took over and hour to come out. Delays due to wind caused rebooking.

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

I didn’t like anything, being platinum pro get you absolutely nowhere and does not increase the customer service treatment whatsoever anymore. My flight was canceled and they put me on a flight eight hours later that would’ve got me back in the middle of the night. They could’ve easily move me up to an hour Prior on an earlier flight. My second flight was unreasonable to take, the third flight was also canceled due to mechanical issues like the first flight. I don’t know what’s going on with American, but they are falling apart, after seven flight changes I finally got home, Unreasonable.

This was a horrible American Airlines experience, and it discourages me from flying with them again. It may have stemmed from a mechanical delay, but it appeared that the team was unprepared to respond to the delay. After boarding, we waited an hour before finally taking off. After landing at our destination, we waited an additional hour on the tarmac waiting for a gate (at 8:00pm) to be assigned and cleared. The flight crew did their best, but they were clearly tired and also ready to be done for the day. Because of the delay, I missed a connecting flight. It was a very poor experience.

Fantastic! If it had not been for a check-in agent in Knoxville I may have not gotten my passes on British Airways. I couldn’t check-in online because British Airways had messed us the info on my tickets to London & Inverness. AA’s was great! British Airways was a continuous series of delays and frustrations.

Wheelchair was waiting for me,changed to a better seat which was great as it's hard for me to walk

Everything you need to know for your flight from Knoxville to Syracuse

Information on your arrival and departure airports