SYR - TYS

$274 Find Cheap Flights from Syracuse to Knoxville - Compare and Save

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Everything you should know

Cheapest round-trip
$287
Typical prices: $295-$444
American Airlines
Sun 11/4Wed 11/7
SYR - TYS • 1 stop
Cheapest one-way
$274
Typical prices: $268-$449
Delta
Thu 10/4
SYR - TYS • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Syracuse and Knoxville. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
13 weeks
in advance
Our data shows that travelers who book at least 13 weeks in advance save around 42% compared to booking last minute.
Insights
Insights
When to travel
January
Cheapest • 29% price drop
October
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Detroit Metropolitan Wayne County (DTW)
Cheapest • Avg $379 (round-trip)
Washington, D.C. Dulles Intl (IAD)
Shortest trip • 4h 32m (one-way)
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Insights
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Flight Deals

Cheap Flights from Syracuse to Knoxville (SYR-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Syracuse to Knoxville

Tue, Oct 20 - Tue, Oct 27
American Airlines Logo
4:35 pm - 10:54 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
6h 19m1 stop Charlotte Douglas
American Airlines Logo
6:20 am - 12:19 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
5h 59m1 stop Charlotte Douglas
$287American Airlines
Wed, Nov 4 - Sat, Nov 7
American Airlines Logo
4:27 pm - 10:48 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
6h 21m1 stop Charlotte Douglas
American Airlines Logo
6:01 am - 12:13 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
6h 12m1 stop Charlotte Douglas
$287American Airlines
Tue, Oct 20 - Tue, Oct 27
American Airlines Logo
1:13 pm - 6:43 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
5h 30m1 stop Charlotte Douglas
American Airlines Logo
6:11 pm - 11:59 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
5h 48m1 stop Washington, D.C. Reagan-National
$287American Airlines
Fri, Oct 30 - Wed, Nov 4
Allegiant Air Logo
8:51 pm - 8:50 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
23h 59m1 stop Orlando Sanford Intl
Allegiant Air Logo
10:55 am - 9:18 amTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
22h 23m1 stop Fort Lauderdale
$293Allegiant Air
Sat, Nov 14 - Fri, Nov 20
Delta Logo
1:25 pm - 8:05 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
6h 40m1 stop Detroit Metropolitan Wayne County
Delta Logo
5:25 pm - 11:00 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
5h 35m1 stop New York LaGuardia
$303Delta
Thu, Oct 22 - Tue, Oct 27
Delta Logo
6:08 am - 11:02 amSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
4h 54m1 stop New York LaGuardia
Delta Logo
6:23 pm - 11:55 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
5h 32m1 stop Atlanta Hartsfield-Jackson
$303Delta
Wed, Oct 14 - Tue, Oct 27
United Airlines Logo
6:00 am - 10:37 amSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
4h 37m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
4:30 pm - 11:43 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
7h 13m2 stops Newark Washington, D.C. Dulles Intl
$312United Airlines
Wed, Oct 21 - Mon, Oct 26
United Airlines Logo
7:53 pm - 11:59 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
4h 06m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
7:35 pm - 11:43 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
4h 08m1 stop Washington, D.C. Dulles Intl
$323United Airlines
Mon, Nov 2 - Fri, Nov 6
Allegiant Air Logo
7:48 pm - 6:52 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
23h 04m1 stop Orlando Sanford Intl
Allegiant Air Logo
1:49 pm - 7:55 pmTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
6h 06m1 stop Orlando Sanford Intl
$390Allegiant Air
Fri, Oct 30 - Thu, Nov 5
Multiple Airlines Logo
8:51 pm - 4:00 pmSYR  Syracuse Hancock Intl-TYS Knoxville McGhee Tyson
19h 09m1 stop Orlando Sanford Intl
Multiple Airlines Logo
6:33 pm - 11:44 amTYS  Knoxville McGhee Tyson-SYR Syracuse Hancock Intl
17h 11m2 stops Jacksonville Raleigh-Durham
$400Multiple Airlines
Booking Insights

Price, demand and travel trends for Syracuse to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Syracuse to Knoxville with more confidence.

How much is a round-trip flight from Syracuse to Knoxville?

Round-trip flights from Syracuse to Knoxville start at $287. Prices are below average for this route right now, with typical round-trip fares ranging from $295 to $444. The lowest price found in the past 5 days was $287 on American Airlines.

What's the cheapest day of the week to fly from Syracuse to Knoxville?

Wednesday is the cheapest day of the week to fly from Syracuse to Knoxville, it is 16% cheaper than the average day. Sunday is the most expensive day with flight prices 34% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Syracuse to Knoxville?

  • January is the cheapest month to fly from Syracuse to Knoxville at $260 round-trip.
  • May ($663) and March ($493) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 155% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Syracuse to Knoxville the cheapest?

Flights from Syracuse to Knoxville are cheapest 13 weeks before departure. Booking in this window typically costs about 42% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Syracuse to Knoxville flights

Low season

June

Cheapest flight

$274
Best time to beat the crowds but there is an average 6% increase in price.
Most popular time to fly with an average 4% increase in price.
Flight from Syracuse to Knoxville

When to book flights from Syracuse to Knoxville

Are your dates flexible? Find out the best times to travel from Syracuse to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Syracuse to Knoxville flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Syracuse to Knoxville?

    Flights from Syracuse to Knoxville usually depart from Syracuse Hancock Intl (SYR) and arrive at Knoxville McGhee Tyson (TYS).

  • What cabin classes can I book on flights from Syracuse to Knoxville?

    Two cabin classes are available on flights from Syracuse to Knoxville:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Syracuse to Knoxville pass through?

    One-stop flights from Syracuse to Knoxville most commonly connect through:

    • Charlotte Douglas (CLT) - 35% of one-stop connections
    • Washington, D.C. Dulles Intl (IAD) - 23% of one-stop connections
    • Washington, D.C. Reagan-National (DCA) - 12% of one-stop connections
    • New York LaGuardia (LGA) - 12% of one-stop connections

    Charlotte Douglas (CLT) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Syracuse to Knoxville?

    Yes. Being flexible with your travel dates can save you up to 38% on the Syracuse to Knoxville route. Wednesday is the cheapest departure day at $308 round-trip on average, while Sunday is the most expensive at $489, a difference of $181. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How expensive are last-minute Syracuse to Knoxville flights?

    Last-minute fares on this route - booked within 2 weeks of departure - run 34% above the route average of $364. Book 13 weeks before departure for the lowest fares.

  • How long is a flight from Syracuse to Knoxville?

    A nonstop flight from Syracuse to Knoxville takes 0h 00m, covering 656 miles.

  • Do I need a passport to fly from Syracuse to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Syracuse to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $287 to $1,992. That means the highest observed fare was about 7x higher than the lowest one.

  • How are flight prices from Syracuse to Knoxville looking right now?

    One-way fares from Syracuse to Knoxville are currently in line with typical prices for this route. Average one-way fares are about $342.

  • How much time can I save by choosing a different layover airport from Syracuse to Knoxville?

    Flying via Washington, D.C. Dulles Intl (IAD) gives the shortest average 1-stop total travel time at 4h 32m, compared with 4h 55m via New York LaGuardia (LGA) and 5h 00m via Atlanta Hartsfield-Jackson (ATL).

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    • Budget
    • Alamo
    • Thrifty
    • Enterprise Rent-A-Car
    • Payless

  • How much should I expect to pay for a Syracuse to Knoxville flight?

    Round-trip flights from Syracuse to Knoxville range from $295 to $444, with an average of $364 over the past 12 months. Anything below $295 counts as a good deal.

Your guide to booking Syracuse to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Wednesday departure instead of Sunday. On this route, Wednesday flights average $308 - about $181 less than Sunday (37% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 13 weeks before you fly. On this route, that window historically saves about 42% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Syracuse to Knoxville trip for January. Fares historically average $260 round-trip in that month - typically $403 less than the most expensive month, which is May (based on the last 12 months).

More options for your flight from Syracuse to Knoxville

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