Which airports can I use when flying from Syracuse to Knoxville?

Flights from Syracuse to Knoxville usually depart from Syracuse Hancock Intl (SYR) and arrive at Knoxville McGhee Tyson (TYS).

What cabin classes can I book on flights from Syracuse to Knoxville?

Two cabin classes are available on flights from Syracuse to Knoxville: • Economy Class • First Class

Which airports do connecting flights from Syracuse to Knoxville pass through?

One-stop flights from Syracuse to Knoxville most commonly connect through: • Charlotte Douglas (CLT) - 31% of one-stop connections • Washington, D.C. Dulles Intl (IAD) - 20% of one-stop connections • New York LaGuardia (LGA) - 14% of one-stop connections • Washington, D.C. Reagan-National (DCA) - 13% of one-stop connections

Can I save money by using flexible dates for flights from Syracuse to Knoxville?

Yes. Flexible dates can save you up to 39% on flights from Syracuse to Knoxville. Wednesday is the cheapest departure day at $308 round-trip on average, while Monday is the most expensive at $497, a difference of $189. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How expensive are last-minute Syracuse to Knoxville flights?

Last-minute fares on this route (booked within two weeks of departure) run 19% above the $367 route average. Book 13 weeks before departure for the lowest fares.

How long is a flight from Syracuse to Knoxville?

A nonstop flight from Syracuse to Knoxville takes 00m, covering 656 miles.

Do I need a passport to fly from Syracuse to Knoxville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Syracuse to Knoxville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $327 to $2,358. That means the highest observed fare was about 7x higher than the lowest one.

How are flight prices from Syracuse to Knoxville looking right now?

One-way fares from Syracuse to Knoxville are currently lower than usual. Average one-way flight prices are about $251, which is 26% below the typical average for this route.

How much time can I save by choosing a different layover airport from Syracuse to Knoxville?

Flying via Washington, D.C. Dulles Intl (IAD) gives the shortest average 1-stop total travel time at 4h 36m, compared with 4h 58m via New York LaGuardia (LGA) and 5h 01m via Detroit Metropolitan Wayne County (DTW).

What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $80 for economy cars. Top options include: • Budget • Alamo • Enterprise Rent-A-Car • Thrifty • Avis

How much should I expect to pay for a Syracuse to Knoxville flight?

Round-trip flights from Syracuse to Knoxville range from $304 to $426, with an average of $367 over the past 12 months. Anything below $304 counts as a good deal.

How much is a round-trip flight from Syracuse to Knoxville?

Round-trip flights from Syracuse to Knoxville typically range from $304 to $426. The lowest price found in the past 5 days was $327, on Delta.

What's the cheapest day of the week to fly from Syracuse to Knoxville?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Syracuse to Knoxville. It’s 17% cheaper than the average day, while Monday is the most expensive, with prices 35% higher.

What’s the cheapest month to fly from Syracuse to Knoxville?

•January is the cheapest month to fly from Syracuse to Knoxville at $260 round-trip. •May ($663) and March ($493) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 155% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Syracuse to Knoxville the cheapest?

Flights from Syracuse to Knoxville are cheapest 13 weeks before departure. Booking in this window typically costs about 35% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Which airline is the cheapest to fly from Syracuse to Knoxville?

Delta ($327) and Allegiant Air ($330) are the cheapest airlines to fly round-trip from Syracuse to Knoxville according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Syracuse to Knoxville?

Charlotte Douglas (CLT) is the most popular layover for the Syracuse to Knoxville route. 31% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via CLT.

What is the cheapest layover airport when flying from Syracuse to Knoxville?

Flights via Detroit Metropolitan Wayne County (DTW) offer the most affordable fares, with an average round-trip price of $379. Based on KAYAK data over the past 3 months.

When flying from Syracuse to Knoxville which airport offers the shortest layover?

Washington, D.C. Dulles Intl (IAD) had the shortest average connection time for Syracuse to Knoxville layovers at 2h 58m over the past 3 months.

$160 CHEAP FLIGHTS from Syracuse to Knoxville (SYR - TYS)

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$327

Typical prices: $304-$426

Delta

Fri 4/6Fri 4/13

SYR - TYS • 1 stop

Cheapest one-way

$160

Typical prices: $268-$449

Allegiant Air

Thu 3/1

SYR - TYS • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Syracuse and Knoxville. You'll need to take a connecting flight to reach the destination.

Insights

When to book

13 weeks

in advance

Our data shows that travelers who book at least 13 weeks in advance save around 35% compared to booking last minute.

Insights

When to travel

January

Cheapest • 29% price drop

October

Most popular

Good to know

Top layover airports

Detroit Metropolitan Wayne County (DTW)

Cheapest • Avg $379 (round-trip)

Washington, D.C. Dulles Intl (IAD)

Shortest trip • 4h 36m (one-way)

Insights

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We hope you love your trip to Knoxville!

Flight Deals

Cheap Flights from Syracuse to Knoxville (SYR-TYS)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Syracuse to Knoxville

Tue, Apr 6 - Tue, Apr 13

5:10 pm - 9:34 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

4h 24m1 stop Detroit Metropolitan Wayne County

5:00 pm - 11:13 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

6h 13m1 stop New York LaGuardia

$327Delta

Wed, Dec 9 - Sat, Dec 12

12:10 pm - 4:45 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

4h 35m1 stop New York LaGuardia

5:40 am - 11:15 amTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

5h 35m1 stop Atlanta Hartsfield-Jackson

$327Delta

Tue, Nov 24 - Tue, Dec 1

6:07 am - 11:03 amSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

4h 56m1 stop New York LaGuardia

11:07 am - 4:39 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

5h 32m1 stop New York LaGuardia

$327Delta

Mon, Dec 21 - Fri, Dec 25

6:56 pm - 8:36 amSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

13h 40m1 stop Fort Lauderdale

11:13 am - 10:55 amTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

23h 42m1 stop Sarasota Bradenton Intl

$330Allegiant Air

Sat, Jan 30 - Sun, Jan 31

4:26 pm - 8:41 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

4h 15m1 stop Charlotte Douglas

6:48 pm - 12:17 amTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

5h 29m1 stop Washington, D.C. Reagan-National

$333American Airlines

Fri, Feb 26 - Mon, Mar 1

6:07 am - 11:18 amSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

5h 11m1 stop Washington, D.C. Reagan-National

7:40 am - 2:43 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

7h 03m1 stop Philadelphia

$339American Airlines

Tue, Nov 24 - Thu, Nov 26

5:40 am - 11:30 amSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

5h 50m1 stop Washington, D.C. Dulles Intl

6:00 am - 2:12 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

8h 12m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$344United Airlines

Tue, Nov 24 - Thu, Nov 26

5:40 am - 11:30 amSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

5h 50m1 stop Washington, D.C. Dulles Intl

6:00 am - 2:12 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

8h 12m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$344United Airlines

Sat, Dec 19 - Wed, Dec 23

11:45 am - 7:35 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

7h 50m1 stop Tampa St. Petersburg

9:49 pm - 8:46 amTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

10h 57m1 stop Orlando Sanford Intl

$347Allegiant Air

Sat, Dec 19 - Fri, Dec 25

7:11 pm - 5:43 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

22h 32m2 stops Fort Lauderdale Jacksonville

11:13 am - 10:55 amTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

23h 42m1 stop Sarasota Bradenton Intl

$387Multiple Airlines

Recent last minute flight deals from Syracuse to Knoxville

Wed, Nov 4 - Wed, Nov 11

6:00 am - 10:58 amSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

4h 58m1 stop Washington, D.C. Reagan-National

3:55 pm - 10:41 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

6h 46m1 stop Philadelphia

$386American Airlines

Wed, Nov 4 - Wed, Nov 11

7:35 pm - 11:59 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

4h 24m1 stop Washington, D.C. Dulles Intl

6:45 am - 2:12 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

7h 27m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$391United Airlines

Thu, Nov 5 - Tue, Nov 10

6:00 am - 11:12 amSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

5h 12m1 stop Philadelphia

11:36 am - 4:59 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

5h 23m1 stop Washington, D.C. Reagan-National

$457American Airlines

Thu, Nov 5 - Tue, Nov 10

11:37 am - 5:37 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

6h 00m1 stop Charlotte Douglas

6:01 am - 12:17 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

6h 16m1 stop Charlotte Douglas

$465American Airlines

Wed, Nov 4 - Wed, Nov 11

10:17 am - 8:54 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

10h 37m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

1:56 pm - 11:43 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

9h 47m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$490United Airlines

Thu, Nov 5 - Tue, Nov 10

5:40 am - 11:30 amSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

5h 50m1 stop Washington, D.C. Dulles Intl

6:45 am - 2:12 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

7h 27m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$504United Airlines

Thu, Nov 5 - Sun, Nov 8

6:00 am - 10:45 amSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

4h 45m1 stop Atlanta Hartsfield-Jackson

5:40 am - 11:06 amTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

5h 26m1 stop Atlanta Hartsfield-Jackson

$634Delta

Thu, Nov 5 - Sun, Nov 8

10:08 am - 10:37 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

12h 29m1 stop Fort Lauderdale

5:22 pm - 6:02 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

24h 40m1 stop Orlando Sanford Intl

$704Allegiant Air

Thu, Nov 5 - Sun, Nov 8

10:08 am - 10:37 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

12h 29m1 stop Fort Lauderdale

5:37 pm - 6:02 pmTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

24h 25m2 stops Memphis Orlando Sanford Intl

$832Allegiant Air

Thu, Nov 5 - Sun, Nov 8

10:08 am - 10:37 pmSYR Syracuse Hancock Intl-TYS Knoxville McGhee Tyson

12h 29m1 stop Fort Lauderdale

7:00 am - 11:44 amTYS Knoxville McGhee Tyson-SYR Syracuse Hancock Intl

28h 44m2 stops Orlando Sanford Intl Raleigh-Durham

$838Multiple Airlines

Booking Insights

Price, demand and travel trends for Syracuse to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Syracuse to Knoxville? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Syracuse to Knoxville departing in april.
What's the cheapest day of the week to fly from Syracuse to Knoxville?: Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Syracuse to Knoxville. It’s 17% cheaper than the average day, while Monday is the most expensive, with prices 35% higher.
What’s the cheapest month to fly from Syracuse to Knoxville? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Syracuse to Knoxville, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •January is the cheapest month to fly from Syracuse to Knoxville at $260 round-trip.
•May ($663) and March ($493) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 155% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.
When are flights from Syracuse to Knoxville the cheapest?: Flights from Syracuse to Knoxville are cheapest 13 weeks before departure. Booking in this window typically costs about 35% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Low season	June
High season	October
Cheapest flight	$160

Beat the crowds with an average 48% drop in travelers.

The most popular month to fly with an average 73% increase in travelers.

One-way flight from Syracuse to Knoxville

When to book flights from Syracuse to Knoxville

Are your dates flexible? Find out the best times to travel from Syracuse to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Syracuse to Knoxville?
Two cabin classes are available on flights from Syracuse to Knoxville:

• Economy Class
• First Class
How long is a flight from Syracuse to Knoxville?
A nonstop flight from Syracuse to Knoxville takes 00m, covering 656 miles.
Do I need a passport to fly from Syracuse to Knoxville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Syracuse to Knoxville flight?
Round-trip flights from Syracuse to Knoxville range from $304 to $426, with an average of $367 over the past 12 months. Anything below $304 counts as a good deal.
How expensive are last-minute Syracuse to Knoxville flights?
Last-minute fares on this route (booked within two weeks of departure) run 19% above the $367 route average. Book 13 weeks before departure for the lowest fares.
Have flight prices from Syracuse to Knoxville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $327 to $2,358. That means the highest observed fare was about 7x higher than the lowest one.
How are flight prices from Syracuse to Knoxville looking right now?
One-way fares from Syracuse to Knoxville are currently lower than usual. Average one-way flight prices are about $251, which is 26% below the typical average for this route.
What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?
Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $80 for economy cars. Top options include:

• Budget
• Alamo
• Enterprise Rent-A-Car
• Thrifty
• Avis
Which airports can I use when flying from Syracuse to Knoxville?
Flights from Syracuse to Knoxville usually depart from Syracuse Hancock Intl (SYR) and arrive at Knoxville McGhee Tyson (TYS).
Which airports do connecting flights from Syracuse to Knoxville pass through?
One-stop flights from Syracuse to Knoxville most commonly connect through:

• Charlotte Douglas (CLT) - 31% of one-stop connections
• Washington, D.C. Dulles Intl (IAD) - 20% of one-stop connections
• New York LaGuardia (LGA) - 14% of one-stop connections
• Washington, D.C. Reagan-National (DCA) - 13% of one-stop connections
Can I save money by using flexible dates for flights from Syracuse to Knoxville?
Yes. Flexible dates can save you up to 39% on flights from Syracuse to Knoxville. Wednesday is the cheapest departure day at $308 round-trip on average, while Monday is the most expensive at $497, a difference of $189.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Syracuse to Knoxville?
Flying via Washington, D.C. Dulles Intl (IAD) gives the shortest average 1-stop total travel time at 4h 36m, compared with 4h 58m via New York LaGuardia (LGA) and 5h 01m via Detroit Metropolitan Wayne County (DTW).

If your dates are flexible, aim for a Wednesday departure and avoid flying on Monday. On this route, Wednesday flights average $308, about $189 less than Monday fares (38% savings) based on the last 12 months.
For the best chance at a low fare, aim to book around 13 weeks before you fly. On this route, that window historically saves about 35% versus last-minute pricing (KAYAK booking data, last 12 months).
If you can choose when to travel, plan your Syracuse to Knoxville trip for January. Fares historically average $260 round-trip in that month - typically $403 less than the most expensive month, which is May (based on the last 12 months).

More options for your flight from Syracuse to Knoxville

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SYR - TYS

$160 Find Cheap Flights from Syracuse to Knoxville - Compare and Save

Everything you should know

Cheap Flights from Syracuse to Knoxville (SYR-TYS)

Recent round-trip flight deals from Syracuse to Knoxville

Recent one-way flight deals from Syracuse to Knoxville

Recent last minute flight deals from Syracuse to Knoxville

Price, demand and travel trends for Syracuse to Knoxville flights

How much is a round-trip flight from Syracuse to Knoxville?

What's the cheapest day of the week to fly from Syracuse to Knoxville?

What’s the cheapest month to fly from Syracuse to Knoxville?

When are flights from Syracuse to Knoxville the cheapest?

Which airline is the cheapest to fly from Syracuse to Knoxville?

What’s the most popular layover airport when flying from Syracuse to Knoxville?

What is the cheapest layover airport when flying from Syracuse to Knoxville?

When flying from Syracuse to Knoxville which airport offers the shortest layover?

Key details for Syracuse to Knoxville flights

Low season

High season

Cheapest flight

When to book flights from Syracuse to Knoxville

Your Syracuse to Knoxville flight questions, answered

Your guide to booking Syracuse to Knoxville flights

More options for your flight from Syracuse to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Syracuse to Knoxville

Find direct flights to and from Syracuse and Knoxville

Flights from domestic origins to Knoxville

Flights to other popular destinations

Find deals for your return flight