Which airports can I use when flying from La Crosse to Louisville?

Flights from La Crosse to Louisville usually depart from La Crosse (LSE) and arrive at Louisville Intl (SDF).

What cabin classes can I book on flights from La Crosse to Louisville?

Only Economy Class is available on flights from La Crosse to Louisville.

Which airports do connecting flights from La Crosse to Louisville pass through?

Most connecting flights from La Crosse to Louisville pass through Chicago O'Hare Intl (ORD), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.

Can I save money by using flexible dates for flights from La Crosse to Louisville?

Yes. Being flexible with your travel dates can save you up to 17% on the La Crosse to Louisville route. Tuesday is the cheapest departure day at $408 round-trip on average, while Wednesday is the most expensive at $491, a difference of $83. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

What popular places can I visit in Louisville?

Some of the most popular sights in Louisville are Louisville Waterfront Park and Masonic Widows and Orphans Home. These are among the most viewed places in Louisville on KAYAK.

Do I need a passport to fly from La Crosse to Louisville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from La Crosse to Louisville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $568 to $944. That means the highest observed fare was about 66% higher than the lowest one.

What is the time difference between La Crosse and Louisville?

Louisville is 1 hour ahead of La Crosse (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Louisville Intl Airport (SDF)?

Louisville Intl Airport (SDF) hosts 5 major car rental companies, with daily rates starting from around $32 for economy cars. Top options include: • Hertz • Dollar • Alamo • Thrifty • Budget

What is the cheapest airline to fly from La Crosse to Louisville?

American Airlines ($568) offered the cheapest round-trip ticket from La Crosse to Louisville in the last 5 days.

What is the cheapest layover airport when flying from La Crosse to Louisville?

Flights via Chicago O'Hare Intl (ORD) offer the most affordable fares, with an average round-trip price of $449. Based on KAYAK data over the past 3 months.

When flying from La Crosse to Louisville which airport offers the shortest layover?

Chicago O'Hare Intl (ORD) had the shortest average connection time for La Crosse to Louisville layovers at 206 minutes over the past 3 months.

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Cheapest round-trip

$568

Typical prices: $408-$491

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LSE - SDF • 1 stop

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Cheap Flights from La Crosse to Louisville (LSE-SDF)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Recent round-trip flight deals from La Crosse to Louisville

Wed, Nov 25 - Sun, Nov 29

12:26 pm - 9:37 pmLSE La Crosse-SDF Louisville Intl

8h 11m1 stop Chicago O'Hare Intl

6:30 pm - 11:56 amSDF Louisville Intl-LSE La Crosse

18h 26m1 stop Chicago O'Hare Intl

$568American Airlines

Wed, Nov 25 - Sun, Nov 29

12:26 pm - 9:37 pmLSE La Crosse-SDF Louisville Intl

8h 11m1 stop Chicago O'Hare Intl

6:30 pm - 11:56 amSDF Louisville Intl-LSE La Crosse

18h 26m1 stop Chicago O'Hare Intl

$568American Airlines

Wed, Nov 25 - Sun, Nov 29

12:26 pm - 12:15 amLSE La Crosse-SDF Louisville Intl

10h 49m2 stops Chicago O'Hare Intl Dallas/Fort Worth

6:24 am - 6:20 pmSDF Louisville Intl-LSE La Crosse

12h 56m1 stop Chicago O'Hare Intl

$605American Airlines

Wed, Nov 25 - Sun, Nov 29

6:50 pm - 4:01 pmLSE La Crosse-SDF Louisville Intl

20h 11m1 stop Chicago O'Hare Intl

10:01 am - 6:20 pmSDF Louisville Intl-LSE La Crosse

9h 19m1 stop Chicago O'Hare Intl

$609American Airlines

Wed, Nov 25 - Sun, Nov 29

12:26 pm - 9:37 pmLSE La Crosse-SDF Louisville Intl

8h 11m1 stop Chicago O'Hare Intl

6:30 pm - 11:56 amSDF Louisville Intl-LSE La Crosse

18h 26m1 stop Chicago O'Hare Intl

$627American Airlines

Wed, Nov 25 - Sun, Nov 29

12:26 pm - 12:15 amLSE La Crosse-SDF Louisville Intl

10h 49m2 stops Chicago O'Hare Intl Dallas/Fort Worth

6:30 pm - 11:56 amSDF Louisville Intl-LSE La Crosse

18h 26m1 stop Chicago O'Hare Intl

$715American Airlines

Wed, Nov 25 - Sun, Nov 29

12:26 pm - 12:20 amLSE La Crosse-SDF Louisville Intl

10h 54m2 stops Chicago O'Hare Intl Charlotte Douglas

6:30 pm - 11:56 amSDF Louisville Intl-LSE La Crosse

18h 26m1 stop Chicago O'Hare Intl

$724American Airlines

Wed, Nov 25 - Sun, Nov 29

12:26 pm - 12:15 amLSE La Crosse-SDF Louisville Intl

10h 49m2 stops Chicago O'Hare Intl Dallas/Fort Worth

5:02 am - 11:56 amSDF Louisville Intl-LSE La Crosse

7h 54m2 stops Charlotte Douglas Chicago O'Hare Intl

$913American Airlines

Booking Insights

Price, demand and travel trends for La Crosse to Louisville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from La Crosse to Louisville with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from La Crosse to Louisville?

Round-trip flights from La Crosse to Louisville start at $568. Prices are above average for this route right now, with typical round-trip fares ranging from $408 to $491. The lowest price found in the past 5 days was $568 on American Airlines.

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When to book flights from La Crosse to Louisville

Are your dates flexible? Find out the best times to travel from La Crosse to Louisville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from La Crosse to Louisville?
Flights from La Crosse to Louisville usually depart from La Crosse (LSE) and arrive at Louisville Intl (SDF).
What cabin classes can I book on flights from La Crosse to Louisville?
Only Economy Class is available on flights from La Crosse to Louisville.
Which airports do connecting flights from La Crosse to Louisville pass through?
Most connecting flights from La Crosse to Louisville pass through Chicago O'Hare Intl (ORD), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.
Can I save money by using flexible dates for flights from La Crosse to Louisville?
Yes. Being flexible with your travel dates can save you up to 17% on the La Crosse to Louisville route. Tuesday is the cheapest departure day at $408 round-trip on average, while Wednesday is the most expensive at $491, a difference of $83. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
What popular places can I visit in Louisville?
Some of the most popular sights in Louisville are Louisville Waterfront Park and Masonic Widows and Orphans Home. These are among the most viewed places in Louisville on KAYAK.
Do I need a passport to fly from La Crosse to Louisville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
Have flight prices from La Crosse to Louisville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $568 to $944. That means the highest observed fare was about 66% higher than the lowest one.
What is the time difference between La Crosse and Louisville?
Louisville is 1 hour ahead of La Crosse (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Louisville Intl Airport (SDF)?
Louisville Intl Airport (SDF) hosts 5 major car rental companies, with daily rates starting from around $32 for economy cars. Top options include:
• Hertz
• Dollar
• Alamo
• Thrifty
• Budget

If your dates can be flexible, aim for a Tuesday departure instead of Wednesday. On this route, Tuesday flights average $408 - about $83 less than Wednesday (17% savings) based on the last 12 months.
If you're arriving late at night and need somewhere to stay, check out these hotels close to Louisville Intl Airport.
- Best Western Louisville Airport Expo
- Days Inn by Wyndham Louisville Airport Fair and Expo Center
- Baymont by Wyndham Louisville Airport South

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Everything you should know

Cheap Flights from La Crosse to Louisville (LSE-SDF)

Recent round-trip flight deals from La Crosse to Louisville

Recent one-way flight deals from La Crosse to Louisville

Price, demand and travel trends for La Crosse to Louisville flights

How much is a round-trip flight from La Crosse to Louisville?

What is the cheapest airline to fly from La Crosse to Louisville?

What is the cheapest layover airport when flying from La Crosse to Louisville?

When flying from La Crosse to Louisville which airport offers the shortest layover?

When to book flights from La Crosse to Louisville

Your La Crosse to Louisville flight questions, answered

Your guide to booking La Crosse to Louisville flights

More options for your flight from La Crosse to Louisville

Complete your trip to Louisville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from La Crosse to Louisville

Find direct flights to and from La Crosse and Louisville

Flights from domestic origins to Louisville

Flights to other popular destinations