LSE - SFO

$544 Find Cheap Flights from La Crosse to San Francisco

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from La Crosse to San Francisco departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from La Crosse to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from La Crosse to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$544
American Airlines
Wed 12/10Sat 12/13
LSE - SFO • 1 stop
Cheapest one-way
Multiple Airlines
Tue 10/28
LSE - SFO • multi-stop
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We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from La Crosse to San Francisco (LSE-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from La Crosse to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from La Crosse to San Francisco

Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
6:00 am - 11:26 amLSE-SFO
7h 26m1 stop
American Airlines Logo
11:15 pm - 9:24 amSFO-LSE
8h 09m1 stop
$544American Airlines
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Wed, Dec 10 - Fri, Dec 12
American Airlines Logo
6:00 am - 11:26 amLSE-SFO
7h 26m1 stop
American Airlines Logo
12:25 am - 5:32 pmSFO-LSE
15h 07m2 stops
$550American Airlines
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Wed, Nov 12 - Sun, Nov 16
American Airlines Logo
6:00 am - 11:25 amLSE-SFO
7h 25m1 stop
American Airlines Logo
6:00 am - 5:32 pmSFO-LSE
9h 32m1 stop
$553American Airlines
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Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
10:00 am - 7:14 pmLSE-SFO
11h 14m2 stops
American Airlines Logo
12:10 pm - 11:52 pmSFO-LSE
9h 42m2 stops
$555American Airlines
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Wed, Nov 12 - Sun, Nov 16
American Airlines Logo
6:00 am - 3:03 pmLSE-SFO
11h 03m2 stops
American Airlines Logo
11:18 pm - 9:20 amSFO-LSE
8h 02m1 stop
$559American Airlines
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Wed, Nov 12 - Sun, Nov 16
American Airlines Logo
6:00 am - 3:03 pmLSE-SFO
11h 03m2 stops
American Airlines Logo
6:00 am - 5:32 pmSFO-LSE
9h 32m2 stops
$615American Airlines
Find Deal
Fri, Mar 13 - Mon, Mar 16
American Airlines Logo
6:14 am - 10:53 amLSE-SFO
6h 39m1 stop
American Airlines Logo
11:59 pm - 2:18 pmSFO-LSE
12h 19m2 stops
$697American Airlines
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Fri, Mar 13 - Mon, Mar 16
American Airlines Logo
1:03 pm - 8:58 pmLSE-SFO
9h 55m2 stops
American Airlines Logo
11:59 pm - 2:18 pmSFO-LSE
12h 19m2 stops
$702American Airlines
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Fri, Mar 27 - Mon, Mar 30
American Airlines Logo
4:46 pm - 11:20 pmLSE-SFO
8h 34m1 stop
American Airlines Logo
10:40 pm - 10:58 amSFO-LSE
10h 18m2 stops
$733American Airlines
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Fri, Mar 27 - Mon, Mar 30
American Airlines Logo
4:46 pm - 11:20 pmLSE-SFO
8h 34m1 stop
American Airlines Logo
5:00 am - 2:18 pmSFO-LSE
7h 18m1 stop
$764American Airlines
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Booking Insights

KAYAK's insights & trends for La Crosse to San Francisco flights

Get data-powered insights and trends into flights from La Crosse to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from La Crosse to San Francisco?

The average price of all round-trip flights from La Crosse to San Francisco clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from La Crosse to San Francisco, look for departures on Saturdays and avoid leaving on a Wednesday, as it's usually the priciest day. When flying back from San Francisco, Saturday is the cheapest day to fly and Friday is the most expensive.

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Good to know

Cheapest flight$544
Flight from La Crosse to San Francisco

When to book flights from La Crosse to San Francisco

Are your dates flexible? Find out the best times to travel from La Crosse to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from La Crosse to San Francisco

  • What is the cheapest flight from La Crosse to San Francisco?

    In the last 3 days, the lowest price for a flight from La Crosse to San Francisco was $544 for a round-trip ticket.

  • Do I need a passport to fly between La Crosse and San Francisco?

    No, a passport isn't needed to fly from La Crosse to San Francisco. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from La Crosse to San Francisco?

    On your way to San Francisco, you’ll fly out from La Crosse. You’ll be landing at San Francisco.

  • Which aircraft models fly most regularly from La Crosse to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from La Crosse to San Francisco?

    oneworld is the only airline alliance operating flights between La Crosse and San Francisco.

  • How does KAYAK find such low prices on flights from La Crosse to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from La Crosse to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from La Crosse to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from La Crosse is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from La Crosse to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to La Crosse with another airline. Booking your flights between La Crosse and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from La Crosse to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from La Crosse up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from La Crosse to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from La Crosse to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from La Crosse to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11033 reviews
6.4Food
7.5Boarding
6.9Entertainment
7.2Comfort
8.0Crew
Airline reviews

We are too tired and frustrated to comment politely at this point

6.0 Goodnancy, Oct 2025PHX - SAN
Read more American Airlines reviews

We are too tired and frustrated to comment politely at this point

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

There is no room, no gluten free options, or any free internet/entertainment. You have to bring your own tablet or smartphone because there are no screens.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

Everything you need to know for your flight from La Crosse to San Francisco

Information on your arrival and departure airports

La Crosse (LSE)
San Francisco (SFO)

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