Which airports can I use when flying from La Crosse to San Francisco?

Flights from La Crosse to San Francisco usually depart from La Crosse (LSE) and arrive at San Francisco (SFO).

What cabin classes can I book on flights from La Crosse to San Francisco?

Only Economy Class is available on flights from La Crosse to San Francisco.

Which airports do connecting flights from La Crosse to San Francisco pass through?

Most connecting flights from La Crosse to San Francisco pass through Chicago O'Hare Intl (ORD), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.

Can I save money by using flexible dates for flights from La Crosse to San Francisco?

Yes. Being flexible with your travel dates can save you up to 25% on the La Crosse to San Francisco route. Tuesday is the cheapest departure day at $495 round-trip on average, while Saturday is the most expensive at $656, a difference of $161. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

What popular places can I visit in San Francisco?

Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

Do I need a passport to fly from La Crosse to San Francisco?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from La Crosse to San Francisco changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $494 to $937. That means the highest observed fare was about 89% higher than the lowest one.

What is the time difference between La Crosse and San Francisco?

San Francisco is 2 hours behind La Crosse (Pacific Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at San Francisco Airport (SFO)?

San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates starting from around $15 for economy cars. Top options include: • Thrifty • Europcar • Dollar • Hertz • Fox

How much should I expect to pay for a La Crosse to San Francisco flight?

Round-trip flights from La Crosse to San Francisco range from $488 to $656, with an average of $537 over the past 12 months. Anything below $488 counts as a good deal.

What is the cheapest airline to fly from La Crosse to San Francisco?

American Airlines ($494) offered the cheapest round-trip ticket from La Crosse to San Francisco in the last 5 days.

What is the cheapest layover airport when flying from La Crosse to San Francisco?

Flights via Chicago O'Hare Intl (ORD) offer the most affordable fares, with an average round-trip price of $657. Based on KAYAK data over the past 3 months.

When flying from La Crosse to San Francisco which airport offers the shortest layover?

Chicago O'Hare Intl (ORD) had the shortest average connection time for La Crosse to San Francisco layovers at 282 minutes over the past 3 months.

$494 CHEAP FLIGHTS from La Crosse to San Francisco (LSE - SFO)

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Cheapest round-trip

$494

Typical prices: $488-$656

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Sat 2/3Wed 2/7

LSE - SFO • 1 stop

When to travel

June

Cheapest • 29% price drop

April

Most popular

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Flight Deals

Cheap Flights from La Crosse to San Francisco (LSE-SFO)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from La Crosse to San Francisco

Wed, Feb 3 - Sun, Feb 7

5:34 am - 11:14 amLSE La Crosse-SFO San Francisco

7h 40m1 stop Chicago O'Hare Intl

2:03 pm - 11:54 pmSFO San Francisco-LSE La Crosse

7h 51m1 stop Chicago O'Hare Intl

$494American Airlines

Tue, Oct 6 - Sat, Oct 10

6:50 pm - 12:30 amLSE La Crosse-SFO San Francisco

7h 40m1 stop Chicago O'Hare Intl

3:18 pm - 11:59 pmSFO San Francisco-LSE La Crosse

6h 41m1 stop Chicago O'Hare Intl

$498American Airlines

Tue, Oct 6 - Sat, Oct 10

12:23 pm - 8:11 pmLSE La Crosse-SFO San Francisco

9h 48m1 stop Chicago O'Hare Intl

5:00 am - 6:20 pmSFO San Francisco-LSE La Crosse

11h 20m2 stops Charlotte Douglas Chicago O'Hare Intl

$503American Airlines

Tue, Oct 6 - Sat, Oct 10

7:00 am - 6:02 pmLSE La Crosse-SFO San Francisco

13h 02m2 stops Chicago O'Hare Intl Dallas/Fort Worth

11:13 am - 11:59 pmSFO San Francisco-LSE La Crosse

10h 46m2 stops Dallas/Fort Worth Chicago O'Hare Intl

$508American Airlines

Sat, Oct 24 - Sat, Oct 31

6:50 pm - 12:30 amLSE La Crosse-SFO San Francisco

7h 40m1 stop Chicago O'Hare Intl

9:12 am - 6:20 pmSFO San Francisco-LSE La Crosse

7h 08m1 stop Chicago O'Hare Intl

$552American Airlines

Thu, Nov 19 - Sun, Nov 22

6:50 pm - 12:16 amLSE La Crosse-SFO San Francisco

7h 26m1 stop Chicago O'Hare Intl

7:13 am - 6:20 pmSFO San Francisco-LSE La Crosse

9h 07m1 stop Chicago O'Hare Intl

$558American Airlines

Thu, Nov 19 - Sun, Nov 22

6:50 pm - 12:16 amLSE La Crosse-SFO San Francisco

7h 26m1 stop Chicago O'Hare Intl

3:04 pm - 12:20 amSFO San Francisco-LSE La Crosse

7h 16m1 stop Chicago O'Hare Intl

$558American Airlines

Wed, Feb 3 - Sun, Feb 7

5:34 am - 3:35 pmLSE La Crosse-SFO San Francisco

12h 01m2 stops Chicago O'Hare Intl Los Angeles

8:37 am - 7:57 pmSFO San Francisco-LSE La Crosse

9h 20m1 stop Chicago O'Hare Intl

$565American Airlines

Tue, Nov 24 - Sat, Dec 5

6:50 pm - 12:16 amLSE La Crosse-SFO San Francisco

7h 26m1 stop Chicago O'Hare Intl

8:47 am - 6:16 pmSFO San Francisco-LSE La Crosse

7h 29m1 stop Chicago O'Hare Intl

$591American Airlines

Booking Insights

Price, demand and travel trends for La Crosse to San Francisco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from La Crosse to San Francisco with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from La Crosse to San Francisco?

Round-trip flights from La Crosse to San Francisco start at $494. Prices are typical for this route right now, with typical round-trip fares ranging from $488 to $656. The lowest price found in the past 5 days was $494 on American Airlines.

Find deals

Low season	January
High season	April
Cheapest flight	$494

Flight from La Crosse to San Francisco

When to book flights from La Crosse to San Francisco

Are your dates flexible? Find out the best times to travel from La Crosse to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from La Crosse to San Francisco?
Only Economy Class is available on flights from La Crosse to San Francisco.
Do I need a passport to fly from La Crosse to San Francisco?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
How much should I expect to pay for a La Crosse to San Francisco flight?
Round-trip flights from La Crosse to San Francisco range from $488 to $656, with an average of $537 over the past 12 months. Anything below $488 counts as a good deal.
Have flight prices from La Crosse to San Francisco changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $494 to $937. That means the highest observed fare was about 89% higher than the lowest one.
What car rental options are available at San Francisco Airport (SFO)?
San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates starting from around $15 for economy cars. Top options include:
• Thrifty
• Europcar
• Dollar
• Hertz
• Fox
Which airports can I use when flying from La Crosse to San Francisco?
Flights from La Crosse to San Francisco usually depart from La Crosse (LSE) and arrive at San Francisco (SFO).
Which airports do connecting flights from La Crosse to San Francisco pass through?
Most connecting flights from La Crosse to San Francisco pass through Chicago O'Hare Intl (ORD), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.
Can I save money by using flexible dates for flights from La Crosse to San Francisco?
Yes. Being flexible with your travel dates can save you up to 25% on the La Crosse to San Francisco route. Tuesday is the cheapest departure day at $495 round-trip on average, while Saturday is the most expensive at $656, a difference of $161. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
What is the time difference between La Crosse and San Francisco?
San Francisco is 2 hours behind La Crosse (Pacific Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.
What popular places can I visit in San Francisco?
Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

If your dates can be flexible, aim for a Tuesday departure instead of Saturday. On this route, Tuesday flights average $495 - about $161 less than Saturday (25% savings) based on the last 12 months.
If you can choose when to travel, plan your La Crosse to San Francisco trip for June. Fares historically average $379 round-trip in that month - typically $518 less than the most expensive month, which is November (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to San Francisco Airport.
- Grand Hyatt At Sfo

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Everything you should know

Cheap Flights from La Crosse to San Francisco (LSE-SFO)

Recent round-trip flight deals from La Crosse to San Francisco

Recent one-way flight deals from La Crosse to San Francisco

Recent last minute flight deals from La Crosse to San Francisco

Price, demand and travel trends for La Crosse to San Francisco flights

How much is a round-trip flight from La Crosse to San Francisco?

What is the cheapest airline to fly from La Crosse to San Francisco?

What is the cheapest layover airport when flying from La Crosse to San Francisco?

When flying from La Crosse to San Francisco which airport offers the shortest layover?

Key details for La Crosse to San Francisco flights

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Your La Crosse to San Francisco flight questions, answered

Your guide to booking La Crosse to San Francisco flights

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