STL - EYW

$137 Find Cheap Flights from St. Louis to Key West - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$251
Typical prices: $325-$628
Multiple Airlines
Fri 12/7Sat 12/15
STL - EYW • 1 stop
Cheapest one-way
$137
Typical prices: $334-$469
Multiple Airlines
Sun 12/30
STL - EYW • 2 stops
Nonstop flights
Not available
There are currently no direct flights between St. Louis and Key West. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
20 weeks
in advance
Our data shows that travelers who book at least 20 weeks in advance save around 53% compared to booking last minute.
Insights
Insights
When to travel
January
Cheapest • 26% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Newark (EWR)
Cheapest • Avg $321 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 5h 22m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from St. Louis to Key West (STL-EYW)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Key West

Mon, Dec 7 - Tue, Dec 15
Multiple Airlines Logo
6:20 pm - 10:19 amSTL  Lambert-St Louis-EYW Key West
14h 59m1 stop Orlando
Multiple Airlines Logo
10:59 am - 11:17 amEYW  Key West-STL Lambert-St Louis
25h 18m2 stops Orlando Atlanta Hartsfield-Jackson
$251Multiple Airlines
Mon, Dec 7 - Tue, Dec 15
Multiple Airlines Logo
6:20 pm - 10:19 amSTL  Lambert-St Louis-EYW Key West
14h 59m1 stop Orlando
Multiple Airlines Logo
10:59 am - 11:17 amEYW  Key West-STL Lambert-St Louis
25h 18m2 stops Orlando Atlanta Hartsfield-Jackson
$253Multiple Airlines
Mon, Dec 7 - Sat, Dec 12
Multiple Airlines Logo
6:20 pm - 10:19 amSTL  Lambert-St Louis-EYW Key West
14h 59m1 stop Orlando
Multiple Airlines Logo
6:26 pm - 11:17 amEYW  Key West-STL Lambert-St Louis
41h 51m2 stops Tampa St. Petersburg Atlanta Hartsfield-Jackson
$262Multiple Airlines
Sat, Feb 27 - Tue, Mar 2
American Airlines Logo
7:34 am - 4:14 pmSTL  Lambert-St Louis-EYW Key West
7h 40m1 stop Charlotte Douglas
American Airlines Logo
6:32 pm - 10:50 pmEYW  Key West-STL Lambert-St Louis
5h 18m1 stop Charlotte Douglas
$343American Airlines
Tue, Nov 24 - Tue, Dec 1
American Airlines Logo
5:00 am - 12:37 pmSTL  Lambert-St Louis-EYW Key West
6h 37m1 stop Charlotte Douglas
American Airlines Logo
4:43 pm - 9:50 pmEYW  Key West-STL Lambert-St Louis
6h 07m1 stop Miami
$343American Airlines
Tue, Feb 9 - Sat, Feb 13
Delta Logo
10:13 am - 4:04 pmSTL  Lambert-St Louis-EYW Key West
4h 51m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 11:39 pmEYW  Key West-STL Lambert-St Louis
6h 39m1 stop Atlanta Hartsfield-Jackson
$343Delta
Tue, Dec 22 - Tue, Dec 29
Delta Logo
6:00 am - 1:55 pmSTL  Lambert-St Louis-EYW Key West
6h 55m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:22 pm - 11:55 pmEYW  Key West-STL Lambert-St Louis
6h 33m1 stop Atlanta Hartsfield-Jackson
$343Delta
Sat, Feb 27 - Tue, Mar 2
American Airlines Logo
7:34 am - 4:14 pmSTL  Lambert-St Louis-EYW Key West
7h 40m1 stop Charlotte Douglas
American Airlines Logo
6:32 pm - 10:50 pmEYW  Key West-STL Lambert-St Louis
5h 18m1 stop Charlotte Douglas
$343American Airlines
Thu, Mar 11 - Tue, Mar 23
United Airlines Logo
6:30 am - 2:32 pmSTL  Lambert-St Louis-EYW Key West
7h 02m1 stop Newark
United Airlines Logo
4:45 pm - 10:12 pmEYW  Key West-STL Lambert-St Louis
6h 27m1 stop Houston George Bush Intcntl
$426United Airlines
Fri, Nov 27 - Fri, Dec 4
United Airlines Logo
7:30 am - 3:29 pmSTL  Lambert-St Louis-EYW Key West
6h 59m1 stop Chicago O'Hare Intl
United Airlines Logo
4:10 pm - 10:59 pmEYW  Key West-STL Lambert-St Louis
7h 49m1 stop Chicago O'Hare Intl
$439United Airlines
Booking Insights

Price, demand and travel trends for St. Louis to Key West flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What's the cheapest day of the week to fly from St. Louis to Key West?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from St. Louis to Key West. It’s 29% cheaper than the average day, while Sunday is the most expensive, with prices 44% higher.

What’s the cheapest month to fly from St. Louis to Key West?

•January is the cheapest month to fly from St. Louis to Key West at $329 round-trip.
•October ($682) and March ($560) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 107% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from St. Louis to Key West the cheapest?

Flights from St. Louis to Key West are cheapest 20 weeks before departure. Booking in this window typically costs about 53% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for St. Louis to Key West flights

Low season

May

Cheapest flight

$137
Beat the crowds with an average 40% drop in travelers.
The most popular month to fly with an average 38% increase in travelers.
One-way flight from St. Louis to Key West

When to book flights from St. Louis to Key West

Are your dates flexible? Find out the best times to travel from St. Louis to Key West based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your St. Louis to Key West flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from St. Louis to Key West?

    Two cabin classes are available on flights from St. Louis to Key West:

    • Economy Class
    • First Class

  • How long is a flight from St. Louis to Key West?

    A nonstop flight from St. Louis to Key West takes 00m, covering 1,102 miles.

  • Do I need a passport to fly from St. Louis to Key West?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a St. Louis to Key West flight?

    Round-trip flights from St. Louis to Key West range from $325 to $628, with an average of $444 over the past 12 months. Anything below $325 counts as a good deal.

  • How expensive are last-minute St. Louis to Key West flights?

    Last-minute fares on this route (booked within two weeks of departure) run 44% above the $444 route average. Book 20 weeks before departure for the lowest fares.

  • How are flight prices from St. Louis to Key West looking right now?

    One-way fares from St. Louis to Key West are currently lower than usual. Average one-way flight prices are about $344, which is 18% below the typical average for this route.

  • What car rental options are available at Key West Airport (EYW)?

    Key West Airport (EYW) hosts 5 major car rental companies, with daily rates averaging $67 for economy cars. Top options include:

    • Dollar
    • Hertz
    • Budget
    • Enterprise Rent-A-Car
    • Alamo

  • Which airports can I use when flying from St. Louis to Key West?

    Flights from St. Louis to Key West usually depart from Lambert-St Louis (STL) and arrive at Key West (EYW).

  • Which airports do connecting flights from St. Louis to Key West pass through?

    One-stop flights from St. Louis to Key West most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 48% of one-stop connections
    • Charlotte Douglas (CLT) - 26% of one-stop connections
    • Miami (MIA) - 13% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 10% of one-stop connections

  • Can I save money by using flexible dates for flights from St. Louis to Key West?

    Yes. Flexible dates can save you up to 51% on flights from St. Louis to Key West. Tuesday is the cheapest departure day at $317 round-trip on average, while Sunday is the most expensive at $640, a difference of $323.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from St. Louis to Key West?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 5h 22m, compared with 5h 32m via Charlotte Douglas (CLT) and 5h 34m via Miami (MIA).

  • What is the time difference between St. Louis and Key West?

    Key West is 1 hour ahead of St. Louis (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Key West?

    Some of the most popular sights in Key West are Duval Street, Key West Historic District and Mallory Square. These are among the most viewed places in Key West on KAYAK.

Your guide to booking St. Louis to Key West flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Sunday. On this route, Tuesday flights average $317, about $323 less than Sunday fares (50% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 20 weeks before you fly. On this route, that window historically saves about 53% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your St. Louis to Key West trip for January. Fares historically average $329 round-trip in that month - typically $353 less than the most expensive month, which is October (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Key West Airport.

    • Parrot Key Hotel & Villas
    • Margaritaville Beach House Key West
    • Havana Cabana at Key West

More options for your flight from St. Louis to Key West

Complete your trip to Key West with a hotel stay or car rental

Car rentals in Key West
Hotels in Key West
Vacations in Key West